I.

Long Essay (Answer 1 out of 3) 1 x 10 = 10

II. Short Essay (Answer 5 out of 7) 5 x 6 = 30
III. Short Answer (Answer all 10) 10 x 2 = 20
IV. Multiple Choice (Answer all 10) 10 x 1 = 10

Total = 70 Marks
I. Multiple Choice
1.Sterilization techniques was introduced by:
a.Louis Pasteur b.Robert Koch
c.Antony Van Leewenhock d.Alexander Fleming
2.All of the following vaccines are developed by Louis Pasteur except:
a.Small Pox b.Cholera
c.Rabies d. Anthrax
3.-------------Bacteria has their peptidoglycan layer
a. Gram +veb. Gram -ve
c. Both 1&2d. None of the above
4.Generation time of bacteria is-----------------
a. 20 hrsb. 20 mins
c. 20 secd. All of the above
5.Which of the following objective of compound Microscope is used for the study of stained
Preparation of bacteria
a. Low Powerb. High Power
c. Oil Immersiond. All the above

6.The process by which, an article, surface or medium is made free from all living micro-
organisms including spores.
a.Sterilizationb.Disinfections
c.Filterisationd.Drying
7.One of the first chemicals to be used for disinfection
a. Ethylene oxide.b.Formaldehyde gas
c.Phenol.d.Benzoyl peroxide
8.The optimum temperature at which most of pathogenic bacteria grow best is called
a. Thermophilic b. Psychrophillic
c. Mesophilic d. Capnophilic
9.Which among the following is an example of dry heat sterilisation
a. Inspissation b. Tyndallisation
b. Hot air oven d. Autoclaving
10.Which type of radiation is used in Cold sterilization
a.Gamma rays b. X rays
c. Infra red rays d. UV rays
11.Which of the following is an example of anaerobic medium
a. MacConkey agar b. Thioglycollate medium
c. Blood agar d. Sabourauds Dextrose agar

12.Clinical infections produce following type of immunity:

a. Natural active b. Natural passive
c. Artificial active d. Artificial passive

13. The smallest unit of antigenicity is known as:

a. Paratope b.Hapten
c.Adjuvant d. None of these

14. Which of the following antibody is strongly effective in agglutination?

a.Ig M b. Ig G
c.Ig A d. Ig D

15. Which of the following test is a tube agglutination test?

A. Widal test B. VDRL
C. Kahn test D. ASO test
16. The antigen used in Weil- Felix test is obtained from
A. Pseudomonas B. E coli
C. Proteus D. Staphylococcus
17. In the first week, typhoid is diagnosed by
A. Widal test B. Stool culture
C. Urine culture D. Blood culture
18. Traveller’s diarrhea is caused by
A. EPEC B. EHEC
C. ETEC D. EIEC
19. Vibrio cholerae was discovered by
A. Robert Koch B. John Snow
C. Louis Pasteur D. Eberth and Gaffky
20. What is the transport medium for cholera
A. Tellurite medium B. Chacko- Nair medium
C. Venkatraman- Ramakrishnan medium D. McLeod’s medium
21. Generation time of tuberculous bacillus is
A. 15 days B. 15 minutes
C. 15 hours D. 15 seconds
22. Leprosy bacilli can be grown in
A. Food pad of mice, nine- branded armadillo B. Tail of guinea pig
C. Testes of albino rats D. Hansen’s media
23. Mitsuda reaction is read after
A. 4 hours B. 4 days
C. 4 weeks D. 4 months

24. Which of the following is true about VDRL test

A. Non- specific B. Slide flocculation test
C. Best followed for drug therapy D. All of the above
25. Weil- Felix reaction is useful in diagnosis of
A. Rickettsial infection B. Viral infection
C. Fungal infection D. Parasitic infection
26. All of the following parasites are protozoa except:
A. Entamoeba histolytica B. Plamodium vivax
C. Balantidium coli D. Echinococcus granulosus
27.Cysts of Entamoeba histolytica are formed in:
A. The lumen of the intestine. B.Thetissuses
 C. The soil D.All of the above
28. Extraintestinal amoebiasis may occur in:
A. Liver B.Lung
C. Brain D.All of the above
29. Leishmania donovani causes
A. Sleeping sickness B.Kala-azar
C. Malaria D. Chaga’s disease
30. Which of the following is intermediate host in malaria?
A. Man B.Femaleanopheles’ mosquito
C. Culex mosquito D.None of the above
31. The common name for Taenia saginata is:
A. The beef tapeworm B.The pork tapeworm
C. The armed tapeworm D.None of the above
32. The larval form of Echinococcus granulosus is named as:
A. Cysticercuscellulosae B.Cysticercusbovis
C. Hydatid cyst D.None of the above

33. Which of the following trematodes live in liver?

A. Fasciolopsisbuski B.Fasciola hepatica
C.Paragonimuswestermani D.Schistosoma haematobium

34. The common name for Ascaris lumbricoides is:

A. Roundworm B.Hookworm
C.Threadworm D.None of the above
35. The common name for Ancylostoma duodenale is:
A. Roundworm B.Hookworm
C. Threadworm D.None of the above
36. Enterobius vermicularis infection in humans may occur by:
A. Raw or inadequately cooked pork B.Autoinfection
C. Penetration of skin by infective larvaeC.None of the above

37. Live vaccines are available for the following except

A. Influenza B.Measles
C. Polio D. Rabies
38. Vector for Dengue fever is
A. Culex B.Anopheles
C. Aedes D. Ticks
39. All of the following are RNA viruses expect:
A. HIV B.Polio
C. Hepatitis A D.Hepatitis B
40. Which of the following viral infections are transmitted sexually:
A. Hepatitis B B. Herpes simplex- 2
C. HIV D. All of these
41. Which of the following vaccine is used in pulse- polio programme:
A. Salk B. Sabin
C. Both A and B D.None of these
42. In pulse polio programme vaccine is given to following age group:
A. 0-5 years B.0-10 years
C. 0-15 years D.All age groups
43. Shape of Rabies virus is like:
A. Bullet B. Rod
C. Brick D.Space vehicle
44. Kissing disease is caused by:
A. Herpes simplex- 1 B.Epstein- Barr virus
C. Cytomegalovirus D. Varicella zoster virus
45. Presence of Reverse transcriptase is a characteristic feature of:
A. Retroviruses B. Reoviruses
C. Rhabdoviruses D. Arboviruses
46. Risk of transmission of HIV infection is highest with:

A. Tissue/ organ donation B.Needle injuries

C.Sexual intercourse D.Blood transfusion
47. Following is a genus of dermatophytes:
A. Epidermophyton B. Trichophyton
C. Microsporum D. All of these
48. Which of the following fungus can cause oral thrush :
A. Candida albicans B. Cryptococcus neoformans
C. Aspergilus D. Mucor
49. Cryptococcus neoformans have been isolated from :
A. Pigeon droppings B. Cat’s faeces
C. Decaying woods D. All of these
50. Aflatoxin is produced by :
A. Aspergillus niger B.Aspergillus fumigatus
C. Aspergillus flavus D. Any of these

GENERAL MICROBIOLOGY

Short Answer

1. List the contributions of Louis Pasteur.

2. Koch’s postulates
3. Negative Staining
4. Name four staining techniques.
5. Name two methods of dry heat sterilization
6. Name four articles sterilized in autoclave
7. What is anaerobic media? Give two examples
8. Name four culture methods

Short notes

1. Robert Koch
2. Bacterial growth curve.
3. Flagella.
4. Pasteurization.
5. Methods of anaerobic cultivation.

Short Essay
 1. Antibiotic Sensitivity Test
2. Classify culture media and describe in detail anaerobic culture methods.
Essay
1. Describe the morphology of a bacterial cell with the help of a neat diagram and
mention the functions of various appendages.
2. Define Sterilization. Discuss about physical methods of sterilization.

Immunology

Short notes
1. Define immunity.
2. Define hapten. Give examples.
3. Diagrammatic representation of IgG.

Short Essay

1. Active immunity
2. Antigens
3. Sources of infection.

SYSTEMIC BACTERIOLOGY

Short answer
1. What is MRSA?
2. Name the non-suppurative complications of Streptococcus pyogenes.
3. Describe the morphology of Corynebacterium diphtheriae.
4. Define zoonosis with examples.
5. Nagler’s reaction.
6. What is significant bacteriuria?
7. Name four organisms causing UTI.
8. TCBS.
9. DOTS.
10. VDRL.

Short notes
1. Coagulase test.
2. Laboratory diagnosis of Neisseria meningitidis.
3. Elek’stoxigenicity test.
4. Prophylaxis of tetanus.
5. Pathogenesis of bacillary dysentery.
6. Classification of Vibrio.
7. Lab diagnosis of pulmonary tuberculosis.
8. Laboratory diagnosis of syphilis.

Short Essay
 1. Describe the morphology, pathogenesis and laboratory diagnosis of Treponema
pallidum.
2. Describe in detail the classification of Shigella, pathogenesis and laboratory diagnosis
of Shigella dysenteriae.

Essay
1. Classify Streptococci. Write in detail the pathogenesis, clinical features, laboratory
diagnosis and treatment of Streptococcus pyogenes.
2. Enumerate the Mycobacteria. Describe the morphology, pathogenesis & laboratory
diagnosis of Mycobacterium tuberculosis. Add a note on BCG vaccine.

VIROLOGY
Short answer
1. Mention differences between bacteria and viruses.
2. Name 4 RNA viruses.
3. What is pulse polio immunization?
4. MMR vaccine.
5. Dengue Haemorrhagic fever.
6. What is hydrophobia?
7. SARS
8. What are retroviruses?

Short notes
1. Herpes simplex virus.
2. Cultivation of virus.
3. Mumps virus.
4. Dengue virus.
5. Prophylaxis of rabies.
Short Essay
1. Classify Hepatitis viruses. Describe the morphology, pathogenesis, laboratory
diagnosis of Hepatitis B virus infection.
2. Describe the morphology, pathogenesis, lab diagnosis and prophylaxis of Rabies
virus.

Essay
1. Classify Human Herpes viruses. Describe the pathogenesis and laboratory diagnosis
of Herpes simplex.
2. Describe the structure, pathogenesis, clinical features and lab diagnosis of human
immunodeficiency virus infection.
MYCOLOGY
Short answer
1. What are the functions of KOH in direct microscopy?

2. Antifungal agents.
3. List the fungi causing opportunistic mycoses
4. Otomycoses
Short notes
 1. Laboratory diagnosis of fungal infection.
2. Candida albicans.
3. Cryptococcus neoformans.
Short Essay
1. Classify superficial mycoses & write in detail about dermatophytes.
2. Name the opportunistic fungal infection .Describe in detail the pathogenesis & lab
diagnosis of candidiasis

PARASITOLOGY
Short answer
1. Draw a neat labelled diagram of Giardia lamblia.
2. Pathogenesis of Blackwater fever.
3. Clinical features in Malaria.
4. Enumerate the differences betweenTaeniasaginata& Taeniasolium?
5. Casoni’s test
6. Name the intestinal nematodes?
7. NIH swab
Short notes
1. Giardiasis
2. Prophylaxis of Malaria
3. Laboratory diagnosis of Taenia solium infection with a note on prophylaxis
4. Laboratory diagnosis of Ascaris lumbricoides.
5. Larva migrans
Short Essay
1. Discuss the morphology, life cycle, pathogenicity and laboratory diagnosis of
Entamoeba histolytica.
2. Describe the morphology, life cycle, and pathogenesis and laboratory diagnosis of
Taenia saginata?
Essay
1. Classify Sporozoa. Describe the life cycle, pathogenesis & laboratory diagnosis of
Plasmodium falciparum.
2. Describe the morphology, life cycle, pathogenesis , clinical features and laboratory
diagnosis ofAscaris lumbricoides?