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ORIGINAL INVESTIGATION
Mersin Üniversitesi Tıp Fakültesi, Anesteziyoloji ve Reanimasyon Anabilim Dalı, Mersin, Turkey
KEYWORDS Abstract
Hip arthroplasty; Background and objective: Pain control is one of the major concerns after major hip surgeries.
Nerve blocks; Suprainguinal fascia iliaca compartment block (S-FICB) is an alternative analgesic technique
Epidural analgesia that can be considered as an effective and less invasive method than epidural analgesia (EA). In
this retrospective study, we compared postoperative analgesic efficacy of single shot ultrasound
guided S-FICB and EA after major hip surgery.
Methods: We retrospectively examined 150 patients who underwent major hip surgeries and
who received S-FICB or EA. Seventy-two patients submitted to EA and 78 patients who received
S-FICB were included and their medical records retrospectively reviewed. Morphine consump-
tions, VAS scores, and side effects were recorded. Patients under antiplatelet or anticoagulant
theraphy were also registered. Morphine consumption and VAS scores were the primary end-
points, succes rate and complications were the secondary endpoints of our study. P-values less
than 0.05 were considered statistically significant.
Results: Morphine consumption was lower at the emergence in the EA group but there was no
statistically significant difference between the two groups according to total opioid consumption
(0 [0-0] vs 0 [0-0]; p = 0.52). There was no difference between VAS scores in the first 18 hours.
Hypotension was significantly higher in the EA group (9 vs 21; p = 0.04).
Conclusion: In conclusion, S-FICB can provide comparable analgesia with EA in the early post-
operative period after hip surgery but VAS scores were found lower in the EA group than S-FICB
group after 18th hour. Hypotension has occured more frequently in patients receiving EA.
© 2021 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. This
is an open access article under the CC BY-NC-ND license (http://creativecommons.org/
licenses/by-nc-nd/4.0/).
∗ Corresponding author.
E-mails: dryalamaoglu@hotmail.com, drazizoglu@mersin.edu.tr (M. Azizoğlu).
https://doi.org/10.1016/j.bjane.2021.07.006
© 2021 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. This is an open access article under the CC BY-NC-ND
license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Brazilian Journal of Anesthesiology 2022;72(3):342---349
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M. Azizoğlu and Ş. Rumeli
Figure 1 Flow diagram of the patient selection for the comparison between the two groups.
follow-up period. Patients were mobilized on the first post- to morphine equivalent (7.5 mg IV meperidine = 1 mg IV
operative day. If the patients complained of weakness, the morphine). Vital signs were tracked by using patient follow
epidural washout method with saline was used and the infu- chart which recorded hourly by nurse in the ICU or ward.
sion rate was decreased. Hypotension (systolic blood pressure < 90), hypoxia (SpO2 <
S-FICB: Single-shot US guided S-FICB was administered 90%), and nausea-vomiting complaints which required any
after intubation and before surgery was initiated. An injec- treatment were reported. Walking ability was evaluated to
tion 0.40---0.60 mL.kg-1 of 0.25% bupivacaine was given using test quadriceps weakness on the second day, in patients with
the US-guided longitudinal suprainguinal approach described complaints associated with walking were evaluated with
by Desmet et al.8 Additional volume was administered if suf- manual muscle test. Postoperative length of hospital stay
ficient local anesthetic distribution was not observed. If VAS and adverse events attributed to opioid use were compared.
score was > 3 after extubation, it was considered a failed In addition, medical history of antiplatelet or anticoagulant
block. Acetaminophen was administered at 20 mg.kg-1 every drug use and the number of patients for whom the analgesic
6 hours, except for patients without pain during the first intervention failed were also recorded.
postoperative 48 hours. In addition, if VAS score was > 3 at
any time postoperatively, PCA was set to 0.5 mg morphine on
demand with 15-minute lockout interval or equivalent dose
Statistical analysis
of meperidine.
All patients were monitorized at least 30 minutes in the
Sample size was calculated with using data for EA in a pre-
PACU after surgery. Therefore, first assessment was carried
vious study and was found 67 patients per group needed
out and pain measurement, morphine consumption, and side
to detect 30% change of morphine consumption between EA
effects at ‘‘zero hour’’ were also recorded in the PACU.
and S-FICB patients with a power of 80% and a risk of 0.05 for
Patients who had pain were given 0.5 mg intravenous mor-
type 1 error.9 Shapiro-Wilk test was used for normality and
phine with the target VAS: Three in this period. Pain levels
comparisons were performed using the Mann-Whitney U test
and morphin consumptions were evaluated by an anesthetist
between the two groups because of non-normally distributed
(SA) in the postoperative pain management team at the
data. Fisher’s exact test was used to compare for categorical
intensive care unit (ICU) and ward. Standard VAS (0---10 cm)
variables. Continous variables were expressed as median and
was used for pain assessment. VAS scores were recorded
interquartiles, categorical variables were expressed as fre-
while at rest (VAS-R) and during active movement (VAS-
quency and percentage. Statistical analysis was performed
M) at postoperative 6th , 12th , 24th , and 48th hours. Daily
with www.e-picos.com New York Software and Medcalc Sta-
morphine consumption at postoperative 6th , 12th , 24th , and
tistical Package program. A p-value < 0.05 was determined
48th hours were also recorded. Meperidine was converted
statistically significant.
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Brazilian Journal of Anesthesiology 2022;72(3):342---349
S-FICB, suprainguinal fascia iliaca compartment block; EA, epidural analgesia; ASA, American Society of Anesthesiologists; COPD, Chronic
Obstructive Pulmonary Disease.
Values were presented as median [Q1---Q3] or %.
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M. Azizoğlu and Ş. Rumeli
Table 5 Comparison to success rate and side effects in the patient groups.
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M. Azizoğlu and Ş. Rumeli
washout technique.27,28 The intermittent bolus method was rehabilitation after unilateral total-hip arthroplasty. Reg Anesth
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surgery within the first 48 hours to reduce mortality.29 How- 5. Chelly JE, Ghisi D, Fanelli A. Continuous peripheral nerve
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using anticoagulant therapy without delay. Neuraxial block 1:i86---96.
is contraindicated in patients receiving antiplatelet or 6. Horlocker TT, Vandermeuelen E, Kopp SL, et al. Regional
anticoagulant, whereas peripheral nerve block may be Anesthesia in the Patient Receiving Antithrombotic or Throm-
administered in compressible regions.6 The injection site for bolytic Therapy American Society of Regional Anesthesia and
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used in patients using antiplatelet or anticoagulant drugs dinal Supra-Inguinal Fascia Iliaca Compartment Block Reduces
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should be monitored more closely due to the development 9. Milligan KR, Convery PN, Weir P, et al. The Efficacy and Safety of
of hematoma in addition to the described complications. Epidural Infusions of Levobupivacaine With and Without Cloni-
dine for Postoperative Pain Relief in Patients Undergoing Total
We conducted a retrospective study, and it was major lim-
Hip Replacement. Anesth Analg. 2000;91:393---7.
itation of our study. Data was collected from well-structured 10. Stevanovska MT, Durnev V, Srceva MJ, et al. Continuous femoral
follow-up records kept by the postoperative pain manage- nerve block versus fascia iliaca compartment block as postop-
ment team. Nevertheless, we could report only clinically erative analgesia in patients with hip fracture. Pril (Makedon
observed side effects. Secondly, urinary retention could not Akad Nauk Umet Odd Med Nauki). 2014;35:85---93.
be evaluated because urinary catheter was inserted as stan- 11. Takeda Y, Fukunishi S, Nishio S, et al. Evaluating the Effect of
dard during the follow-up period. Additionally, there was no Intravenous Acetaminophen in Multimodal Analgesia After Total
standard preoperative analgesia management for hip frac- Hip Arthroplasty: A Randomized Controlled Trial. J Arthroplasty.
ture patients. Finally, VAS scores and opioid consumption 2019;34:1155---61.
amounts were recorded only once during the emergence 12. Steenberg J, Møller AM. Systematic review of the effects of
fascia iliaca compartment block on hip fracture patients before
period.
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In conclusion, single-shot S-FICB may provide similar post- study on combined general anesthesia with either continuous
operative pain control as compared to EA in the first 18 fascia iliaca block or epidural anesthesia in patients undergo-
hours after hip surgery. However, VAS scores were lower in ing lower limb orthopedic surgeries. Ain-Shams J Anesthesiol.
the EA group than S-FICB group after the 18th hour. There 2016;9:76---82.
was no statistically significant difference between the two 15. Dalens B, Vanneuville G, Tanguy A. Comparison of the fascia ili-
groups according to total opioid consumption in the first 48 aca compartment block with the 3-in-1 block in children. Anesth
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16. Kumar K, Pandey RK, Bhalla AP, et al. Comparison of
receiving EA but other side effects were similar between
conventional infrainguinal versus modified proximal suprain-
two groups. guinal approach of Fascia Iliaca Compartment Block for
postoperative analgesia in Total Hip Arthroplasty. A prospec-
tive randomized study. Acta Anaesthesiol Belg. 2015;66:
Conflicts of interest 95---100.
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The authors declare no conflicts of interest. outcomes in the context of mode of anaesthesia for patients
undergoing hip fracture surgery: systematic review and meta-
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