Ciprofloxacine

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CIPROFLOXACIN - CIPRO ®

200 mg\100 ml

USUAL DILUENTS
D5W
Standard Dilutions [Amount of drug] [Infusion volume] [Infusion rate]
If 'Ready-to-Use' prep not available:
[200 mg] [100 ml] [1 hour]

Primary:
-------Ready to Use------------
Ciprofloxacin in 5% dextrose injection, USP is available in 200 mg and 400 mg strengths. The 2 mg/mL infusion
solution is supplied in latex-free flexible containers as follows:
SIZE STRENGTH
100 mL, 5% Dextrose 200 mg

STABILITY / MISCELLANEOUS
STABILITY DATA:

Stability Stability Reconstituted P-Insert


Drug Refrigerated Room Temp. Vial/Powder Notes Updated
Protect from light,
Store in a avoid excessive
refrigerator, 2 to 8°C Store at 20 to 25°C heat, protect from
Ciprofloxacin (36 to 46°F) (68 to 77°F) Solution freezing. 08 26 16

EXP: 14 DAYS (RT/REF).


Cipro 400mg ivpb produces the same levels as 500mg tablet.

DOSAGE AND ADMINISTRATION – ADULTS


Ciprofloxacin injection should be administered to adults by intravenous infusion over a period of 60 minutes at dosages
described in the Dosage Guidelines table. Slow infusion of a dilute solution into a larger vein will minimize patient
discomfort and reduce the risk of venous irritation. (See Preparation of Ciprofloxacin Injection for Administration
section.)
The determination of dosage for any particular patient must take into consideration the severity and nature of the
infection, the susceptibility of the causative microorganism, the integrity of the patient’s host-defense mechanisms, and
the status of renal and hepatic function.
ADULT DOSAGE GUIDELINES

Infection* Severity Dose Frequency Usual Duration


Urinary Tract Mild/Moderate 200 mg q12h 7-14 Days
Severe/Complicated 400 mg q12h 7-14 Days
Lower Respiratory Mild/Moderate 400 mg q12h 7-14 Days
Tract Severe/Complicated 400 mg q8h 7-14 Days
Nosocomial Mild/Moderate/Severe 400 mg q8h 10-14 Days
Pneumonia

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