Wa0020.
Wa0020.
Wa0020.
PLAN OF DISSERTATION
FOR MASTER OF SCIENCE IN NURSING
(MEDICAL SURGICAL NURSING)
SUBMITTED
TO
UNIVERSITY OF JAMMU
BY
SHARAFAT MAJEED
STEPHENS COLLEGE OF NURSING
MIRAN SAHIB
JAMMU – 181101
BIO-DATA
DATE:
PLACE: Stephens college of nursing,
Miran sahib, Jammu SIGNATURE OF THE CANDIDATE
I
CERTIFICATE
Certified that I am willing to act as a guide for the title “A DESCRIPTIVE STUDY
TO ASSESS THE KNOWLEDGE AND PRACTICE OF SELF-CARE
REGARDING TRANSMISSION, PREVENTION, AND MANAGEMENT OF
PULMONARY TUBERCULOSIS AMONG STAFF NURSES WORKING AT
GMC JAMMU WITH A VIEW TO DEVELOP INFORMATION BOOKLET”. It
will be ensured that the data being included in the dissertation will be genuine and work
will be conducted by the candidate himself/herself under my supervision and guidance.
There will be no conflict of interest involved.
GUIDE
MRS. SARLA RAINA
Prof. Department of Medical-Surgical Nursing
Stephens College of Nursing, Jammu
II
TABLE OF CONTENT
1 INTRODUCTION 1-6
4 METHODOLOGY 15-18
5 BIBLIOGRAPHY 19-21
7 CONSENT FORM 24
III
IV
INTRODUCTION
“Tuberculosis is once again proving itself to be one of the smartest killers that humanity
has ever faced”
~ Kathryn Lougheed
According to the World Health Organization (WHO), air pollution causes 8.1
million deaths per year, with 3.8 million (47%) attributed to household air pollution
(HAP) from burning biomass for domestic cooking, heating, and lighting. Vulnerable
populations, such as those at the extremes of age, the chronically ill, or individuals of
low socioeconomic status, are at high risk for pollution-related diseases like
pneumonia. Approximately 90% of the 10 million new tuberculosis (TB) cases in 2018
were from low and middle-income countries (LMICs). That year, around 1.3 million
people died from TB, including 251,000 deaths (nearly 20%) among people living with
HIV (PLHIV). In 2020, a similar trend was observed, with the COVID-19 pandemic
causing substantial disruptions to health services. Air pollution is one of the highest-
1
ranking independent risk factors in the global burden of disease. HAP negatively
impacts multiple organ systems and has been linked to an increased risk of developing
TB, according to the 2020 global burden estimation study. However, it is unclear if HAP
independently affects TB risk in PLHIV. Due to compositional similarities between
tobacco and biomass smoke, it is reasonable to expect that HAP's health effects may be
similar to those of tobacco smoke, which doubles the risk of developing TB among
PLHIV compared to their counterparts.2
2
identify it by dyeing the bacilli bright red against a blue background. Humans are the
only natural hosts, and the bacterium primarily spreads through airborne aerosols from
infectious individuals, though transdermal and gastrointestinal (GI) transmission is also
possible.4
3
NEED OF THE STUDY
Despite 90 years of vaccination and 60 years of chemotherapy, tuberculosis
(TB) remains the leading cause of death from an infectious agent, surpassing HIV/AIDS
(WHO 2015b, 2016a). The World Health Organization (WHO) estimates about 10.4
million new TB cases and 1.8 million deaths annually, with one-third of cases
undetected by health systems and many not receiving proper treatment. TB, caused by
Mycobacterium tuberculosis, spreads through respiratory transmission, primarily
affecting the lungs but capable of damaging any tissue. Only 10 percent of those
infected develop active TB, while the rest contain the infection. The bacterium can
remain latent for years and reactivate, especially in individuals with HIV/AIDS or other
immune-compromising conditions. Treatment involves multiple drugs over several
months, challenging for patients and healthcare systems, particularly in low- and
middle-income countries (LMICs). Drug-resistant TB, requiring longer and more
difficult treatments, is increasing. Diagnosis in LMICs often relies on smear
microscopy, which detects only 50–60 percent of cases. Delays in diagnosis and
treatment facilitate transmission. The widely used BCG vaccine has variable and
incomplete effectiveness, and more effective vaccines are needed to eliminate TB in
high-incidence areas.5
The Ministry of Health and Family Welfare has responded to the WHO Global
TB Report 2022, released on October 27, 2022, highlighting India's superior
performance on key metrics over time compared to other countries. For 2021, India's
TB incidence was 210 per 100,000 population, showing an 18% decline from the
baseline year of 2015 when the incidence was 256 per lakh population. This decline is
better than the global average of 11% and places India at the 36th position in incidence
rates globally. Despite the disruptions caused by the COVID-19 pandemic, India
successfully mitigated its impact on TB programs through critical interventions in 2020
and 2021, resulting in over 21.4 lakh TB cases being notified—18% higher than in
2020. Key measures contributing to this success include mandatory case notification
and intensified door-to-door Active Case Finding drives, screening over 22 crore people
in 2021. Enhanced diagnostic capabilities, with over 4,760 molecular diagnostic
4
machines across the country, have also played a crucial role. The Ministry
communicated to WHO those domestic studies are underway to provide more accurate
estimates of TB incidence and mortality, with data expected in early 2023. WHO
acknowledged this, noting that India's TB estimates for 2000–2021 are interim and
subject to finalization in consultation with India's Ministry of Health & Family
Welfare.6
5
patients, controlling pathogen spread, and minimizing time spent in healthcare
facilities. Another essential measure is the baseline and serial screening for latent TB
infection in HCWs at risk of exposure. While the interferon-gamma release assay offers
some advantages over the tuberculin skin test, it also has significant limitations,
primarily due to its high conversion rate.8
PROBLEM STATEMENT
“A descriptive study to assess the knowledge and practice of self-care regarding
transmission, prevention, and management of Pulmonary Tuberculosis among
staff nurses working at GMC Jammu with a view to develop information booklet”
OBJECTIVES
1. To assess the level of knowledge regarding the transmission, prevention, and
management of Pulmonary Tuberculosis among Staff Nurses working at GMC
Jammu.
2. To assess the level of practice of self-care regarding the transmission,
prevention, and management of Pulmonary Tuberculosis among Staff Nurses
working GMC Jammu.
3. To determine the relationship between knowledge and practice of self-care
regarding transmission, prevention, and management of Pulmonary
Tuberculosis among Staff Nurses working at GMC Jammu.
4. To prepare an information booklet regarding transmission, prevention, and
management of Pulmonary Tuberculosis among Staff Nurses working at GMC
Jammu.
OPERATIONAL DEFINITIONS
Assess: It refers to estimating or judging the knowledge regarding awareness of
transmission, prevention, and management of Pulmonary Tuberculosis among Staff
Nurses.
Structured Teaching Program: It refers to the systematic plan of activities and on organized
group teaching program by lecture method to impart knowledge regarding awareness of
transmission, prevention, and management of Pulmonary Tuberculosis among Staff
Nurses.
6
Pulmonary tuberculosis (TB): It refers as a contagious bacterial infection caused by
Mycobacterium tuberculosis that primarily affects the lungs.
Transmission: It refers to the process by which an infectious agent is spread from one host
to another, often through direct or indirect contact.
HYPOTHESIS
H0 = There will be no significant difference in the level of knowledge between the pre-test
and post-test knowledge score regarding the effectiveness of knowledge regarding
awareness of transmission, prevention, and management of Pulmonary Tuberculosis
among Staff Nurses.
H1 = There will be a significant difference in the level of knowledge between the pre-test and
post-test knowledge score regarding awareness of transmission, prevention, and
management of Pulmonary Tuberculosis among Staff Nurses at P>0.05 level of
significance.
DELIMITATIONS
• The study will be limited to Staff Nurses working at GMC Jammu.
• The study will be limited to those who are willing to participate.
VARIABLES
• Sociodemographic Variables: age, gender, educational level, years of professional
experience, marital status, and department or unit of work within the hospital.
• Research variables: Knowledge and practice of self-care regarding transmission,
prevention, and management of pulmonary tuberculosis among staff nurses.
7
REVIEW OF LITERATURE
Vigenschow A, Edoa JR, et al 2021 conducted a study on the survey to assess
knowledge, attitude, and practice among healthcare workers in 20 healthcare facilities
in Moyen-Ogooué province, Gabon. A total of 103 questionnaires were completed, with
knowledge questions scored and categorized into four levels. Factors associated with
high knowledge levels were identified using Fisher’s Exact test. Results showed that
40.8% of participants had intermediate knowledge, 28.2% had good knowledge, 21.4%
had poor knowledge, and 9.7% had excellent knowledge. High knowledge levels were
significantly associated with profession, education level, type of healthcare facility, and
previous TB training. Attitudes were generally positive, but 72.8% of participants
feared TB infection and 98.1% saw a need for improved TB control measures.9
8
for knowledge and 6% for practice. Knowledge was not significantly associated with
socio-demographic characteristics. However, work experience was significantly
associated with the practice, as nurses with over 18 years of experience had lower odds
of obtaining good practice scores (OR 0.25, 95% CI 0.06–0.94).11
9
by QFT-GIT, and 13.5% by both. Prior exposure to sputum smear-positive TB doubled
the risk of LTBI. Three participants (1.5%) developed active TB during the study, all
with positive TST and QFT-GIT at baseline.13
Cho KS. 2018 conducted a study on the republic of Korea has the highest tuberculosis
(TB) incidence and mortality rates among OECD countries, with rates of 77 and 5.2 per
100,000 people, respectively (2016). Despite a significant decline in TB cases among
teens and individuals in their 20s due to school screening and contact investigation, the
incidence among the elderly remains high and is increasing. Older individuals represent
10
42% of all TB cases and 82% of TB-related deaths. Improvements in TB treatment
success are attributed to enhanced programs, including compliance control and
insurance coverage. The study advocates for policymakers to concentrate on strategies
to further reduce TB incidence, guided by the 2nd National Strategic Plan for
Tuberculosis Control (2018–2022).16
Lydia Uden, Ella Barber, et al 2017 conducted a review study on the risk of
tuberculosis infection and disease for healthcare workers. A systematic review
identified 21 studies from the past decade, encompassing data from 30,961 HCWs
across 16 countries. The prevalence of LTBI among HCWs was 37%, with an average
incidence rate of active TB at 97 per 100,000 per year. HCWs had a higher risk of LTBI
(odds ratio [OR] 2.27; 95% confidence interval [CI] 1.61–3.20) and active TB
(incidence rate ratio 2.94; 95% CI 1.67–5.19) compared to the general population. The
odds ratio for LTBI was 1.72 with the tuberculin skin test and 5.61 with the interferon-
gamma release assay.17
11
assessed associations between TB infection and various factors, with P < 0.05 indicating
significance. Of the 206 HCWs who completed the questionnaires, ages ranged from
18 to 71 years (mean age 27.13 years). The mean TST induration size was 6.37 mm,
and 36.8% (76/206) had TB infection based on TST results. No TST-positive HCWs
had active TB upon further evaluation. However, two initially TST-negative HCWs
developed pulmonary.19
Surie D, Interrante JD, et al 2017 conducted a study on policies, practices, and
barriers to implementing tuberculosis preventive treatment. This study assessed
Tuberculosis preventive treatment (TPT) implementation in 42 countries supported by
the US President's Emergency Plan for AIDS Relief (PEPFAR). From July to December
2017, TB-HIV program staff at US CDC offices in these countries were surveyed about
TPT policies, practices, and barriers. Of the 42 eligible countries, 35 (83%) completed
the survey. TPT was included in national guidelines in 33 (94%) countries, but only 21
(60%) had nationwide programmatic implementation. HIV programs led TPT
implementation in 20 of 32 (63%) countries, while TB programs led drug procurement
in 18 of 32 (56%) countries. Frequent stock outs were reported, with 21 of 28 (75%)
countries experiencing at least one isoniazid shortage in the past year.20
Carrie Tudor, Martie L. Van der Walt, et al 2016 conducted a case-control study on
occupational risk factors for tuberculosis among healthcare workers in KwaZulu-Natal,
South Africa. This case-control study was conducted among healthcare workers
(HCWs) in three district hospitals with specialized multidrug-resistant (MDR)
tuberculosis wards in KwaZulu-Natal, South Africa, researchers reviewed 1,427
occupational health records over a five-year period (January 2006–December 2010).
The hospitals, which varied in size from 170 to 280 beds and employed between 332
and 700 HCWs, reported 117 (8%) cases of tuberculosis. By July 2011–January 2012,
83 of these cases were still alive and working. Of 307 distributed questionnaires, 145
(47%) were returned, with 54 (37%) from cases and 91 (63%) from controls. Cases
were more likely to respond than controls (65% vs. 41%, P < .01), and responders had
longer hospital tenures and higher HIV infection rates (12% vs. 7%, P = .04).21
12
International Standards for TB Care as a benchmark. Of the 47 studies included, 35
were questionnaire surveys and 12 used chart abstractions; none assessed actual
practice using standardized patients. Due to heterogeneity, meta-analysis was not
possible. Among 22 studies on provider knowledge of sputum smears for diagnosis, 10
found less than half had correct knowledge. Three of four studies on self-reported
practices showed less than a quarter ordered smears for patients with chest symptoms.
In 11 of 14 studies on treatment knowledge, less than one-third of providers knew the
standard regimen for drug-susceptible TB. Adherence to standards in practice was
generally lower than correct knowledge of those standards. Eleven studies comparing
public and private providers found higher levels of appropriate knowledge and practice
in the public sector.22
13
METHODOLOGY
Research methodology refers to the systematic approach used to conduct research. It
encompasses the principles, techniques, and procedures for collecting and analyzing data.
This includes defining the research problem, selecting appropriate research designs (e.g.,
experimental, observational), and choosing methods for data collection (e.g., surveys,
interviews). It also involves deciding on data analysis techniques to interpret the results and
ensure validity and reliability. A well-defined methodology helps ensure that the research
findings are credible, reproducible, and applicable. It guides researchers in systematically
addressing their research questions and drawing meaningful conclusions.
RESEARCH APPROACH
Research approach is the umbrella term that covers the basic procedure for conducting
research. It involves the description of the plan to investigate the phenomenon under
study in a structured (quantitative), unstructured (qualitative) or combination of the
two.
RESEARCH DESIGN
Research design is a master plan specifying the methods and procedures for collecting and
analyzing the needed information in a research study.
14
A descriptive design will be used in this study.
RESEARCH SETTING
The setting is the physical location and condition in which data takes place in the study.
The present study will be conducted in GMC Jammu.
STUDY POPULATION
The population of the study will be both male and female staff Nurses.
TARGET POPULATION
The target population consists of the total number of population or objects which are
meeting the designated set of criteria. The population of this study will be both male
and female staff Nurses of GMC Jammu.
ACCESSIBLE POPULATION
Staff Nurses of GMC Jammu who will be available during data collection and who
fulfil the inclusion and exclusion criteria.
SAMPLING TECHNIQUE
A purposive sampling technique will be used for the present study.
SAMPLE SIZE
The total sample size for the present study will be 100 participants (staff Nurses).
INCLUSION CRITERIA
• Participants should be regular working staff nurses at GMC Jammu.
• Participants staff nurses who will be willing to participate in this study.
EXCLUSION CRITERIA
• Students who will not be available during data collection
• Participants who are not interested in the study.
• Participants who had a major physical illness during data collection.
15
SELECTION AND DEVELOPMENT OF TOOL
The tool used in the study will be divided into three parts:
PILOT STUDY
The pilot study will be conducted to ensure the tool’s reliability and feasibility of the
study on one-tenth of the sample.
16
Analysis and interpretation of data will be based on objectives and done by using
descriptive and inferential statistics.
.
ETHICAL CONSIDERATION
• Ethical clearance obtained from the hospital.
• Permission will be taken from in charge of ward and CMO
• Written informed consent from participants.
17
RESEARCH APPROACH AND RESEARCH DESIGN
Quantitative research approach and descriptive research design
RESEARCH SETTING
GMC Jammu
POPULATION
male and female staff Nurses
TARGET POPULATION
male and female staff Nurses of GMC Jammu
18
REFERENCES
1. World Health Organization. Tuberculosis [Internet]. World Health Organization.
2023. Available from: https://www.who.int/news-room/fact-
sheets/detail/tuberculosis
7. Bloom BR, Atun R, Cohen T, Dye C, Fraser H, Gomez GB, et al. Tuberculosis
[Internet]. 3rd ed. Holmes KK, Bertozzi S, Bloom BR, Jha P, editors. PubMed.
Washington (DC): The International Bank for Reconstruction and Development /
The World Bank; 2017. Available from:
https://www.ncbi.nlm.nih.gov/books/NBK525174/
9. Vigenschow A, Edoa JR, Adegbite BR, Agbo PA, Adegnika AA, Alabi A, et al.
Knowledge, attitudes and practices regarding tuberculosis amongst healthcare
19
workers in Moyen-Ogooué Province, Gabon. BMC Infectious Diseases. 2021 May
27;21(1).
11. Akande PA. Knowledge and practices regarding tuberculosis infection control
among nurses in Ibadan, south-west Nigeria: a cross-sectional study. BMC Health
Services Research. 2020 Apr 6;20(1).
15. Go U, Park M, Kim UN, Lee S, Han S, Lee J, et al. Tuberculosis prevention and
care in Korea: Evolution of policy and practice. Journal of Clinical Tuberculosis
and Other Mycobacterial Diseases. 2018 May;11:28–36.
16. Cho KS. Tuberculosis control in the Republic of Korea. Epidemiology and Health.
2018 Aug 2;40:e2018036.
17. Uden L, Barber E, Ford N, Cooke GS. Risk of Tuberculosis Infection and Disease
for Health Care Workers: An Updated Meta-Analysis. Open forum infectious
diseases [Internet]. 2017;4(3):ofx137. Available from:
https://www.ncbi.nlm.nih.gov/m/pubmed/28875155/
20
19. Ganesan V, Janagond A, Vijay Kumar G, Ramesh A, Anand P, Mariappan M.
Screening of health-care workers for latent tuberculosis infection in a Tertiary
Care Hospital. International Journal of Mycobacteriology. 2017;6(3):253.
20. Surie D, Interrante JD, Pathmanathan I, Patel MR, Anyalechi G, Cavanaugh JS, et
al. Policies, practices and barriers to implementing tuberculosis preventive
treatment—35 countries, 2017. The International Journal of Tuberculosis and
Lung Disease. 2019 Dec 1;23(12):1308–13.
21. Tudor C, Van der Walt ML, Margot B, Dorman SE, Pan WK, Yenokyan G, et al.
Occupational Risk Factors for Tuberculosis Among Healthcare Workers in
KwaZulu-Natal, South Africa. Clinical Infectious Diseases [Internet]. 2016 Apr
26;62(suppl 3):S255–61. Available from:
https://academic.oup.com/cid/article/62/suppl_3/S255/2566632
23. Demissie Gizaw G, Aderaw Alemu Z, Kibret KT. Assessment of knowledge and
practice of health workers towards tuberculosis infection control and associated
factors in public health facilities of Addis Ababa, Ethiopia: A cross-sectional
study. Archives of Public Health [Internet]. 2015 Mar 25;73(1). Available from:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377015/
21
DESCRIPTION OF THE TOOL
In the current study, the data collection will be done by using the self-structured
questionnaire. The tool will help the researcher, to assess the level of knowledge
regarding the transmission, prevention, and management of Pulmonary Tuberculosis
among Staff Nurses working at GMC Jammu.
22
DEMOGRAPHIC VARIABLES
PART A
Age, gender, educational level, years of
professional experience, marital status, and
department or unit of work within the hospital.
SCORING PROCEDURE
For a knowledge questionnaire to assess the knowledge regarding the transmission,
prevention, and management of Pulmonary Tuberculosis among Staff Nurses working
at GMC Jammu.
23
Maximum Score = 36
Minimum Score = 0
Each question carries four answers. Each correct answer carries one mark (1) and the
wrong answer carries a zero mark (0)
CONSENT FORM
The subject ________________________________ has been fully informed about the
nature and purpose of the study. The subject has been asked if any questions have arisen
24
regarding the study and these questions have been answered to the best of the
investigation ability. A signed copy of this form will be made available to the subject.
Investigator’s signature:
____________________
I agree to participate in the study, “A descriptive study to assess the knowledge and
practice of self-care regarding transmission, prevention, and management of Pulmonary
Tuberculosis among staff nurses working at GMC Jammu with a view to develop
information booklet”
I have been allowed to ask questions and have been answered to my satisfaction.
I furthermore recognize the fact that I am free to withdraw this consent and to
discontinue participation in this project at any time without prejudice to care.
Signature: ______________________________
25