Course Specification of Pharmaceutics I

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Republic of Yemen

Minster of Higher Education ‫الجوهىريت اليونيت‬


and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

Course Specification of Pharmaceutics I


I. Course Identification and General Information:
Course Title:
1 Pharmaceutics I
2 Course Number & Code: Ph234
C.H Total
Theoretical Practical Training Seminar
3 Credit hours: 3hrs
2 2 3

Study level/ semester at which this Second year/First semester


4
course is offered:
5 Pre –requisite (if any): Physical pharmacy- Pharmaceutical calculations
6 Co –requisite (if any):
Program (s) in which the course is Bachelor of Pharmacy
7
offered:
8 Language of teaching the course: English
The department in which the course Pharmaceutics and Industrial Pharmacy
9 is offered:

10 Location of teaching the course: Faculty of Pharmacy-Sana’a University


11 Prepared by: Prof. Dr. Abdulwali Ahmed Saif
12 Date of approval:

II. Course description:


This course aims to provide the students with the basic knowledge of pharmaceutics and different pharmaceutical
dosage forms and the route of drug administration. It focused on the advantages and disadvantages, additives
methods of formulation and methods of evaluation of solutions and colloids as pharmaceutical liquid dosage forms.

‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

1
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

III. Intended learning outcomes (ILOs) of the course:


At the end of this course, the students will be able to:

1. Recognize the characteristics of different pharmaceutical dosage forms and routes of drug administration.
2. Describe the advantages and disadvantages of pharmaceutical liquid dosage forms.
3. Recognize the different additives used in manufacturing of pharmaceutical solutions and colloids.
4. Describe methods of preparation of pharmaceutical solutions and colloids.
5. Discuss the method of evaluation of pharmaceutical solutions and colloids.
6. Distinguish pharmaceutical liquid dosage forms.
7. Determine the appropriate methods for preparation of solutions and colloids.
8. Select the suitable method for evaluation of pharmaceutical liquid dosage forms.
9. Propose best approaches to solve the problems encountered in formulation pharmaceutical liquid dosage
forms.
10. Select and practice different methods for preparation of pharmaceutical liquid dosage forms.
11. Formulate different pharmaceutical liquid dosage forms.
12. Label the different formulations of pharmaceutical liquid dosage forms.
13. Evaluate the formulations of pharmaceutical liquid dosage forms.
14. Implement writing and presentation skills.
15. Work independently or collaboratively to prepare seminars/ presentations or write reports.
16. Effectively use internet resources to search for up-to-date information to solve emerging problems.

IV. Intended learning outcomes (ILOs) of the course:


(A) Knowledge and Understanding:
Knowledge and
Alignment of Course Intended Learning Outcomes (CILOs) to Program Intended Learning Outcomes (PILOs) in :
Understanding.
Program Intended Learning Outcomes (Sub- Course Intended Learning Outcomes (CILOs) in:
PILOs) in: Knowledge and Understanding
Knowledge and Understanding
After completing this program, students will be able to: After completing this course, students will be able to:

A1- Recognize the principles of physical, a1- Recognize the characteristics of different pharmaceutical
chemical, clinical, social, behavioral, health dosage forms and routes of drug administration.
and pharmaceutical sciences.
A2- Recognize the physicochemical properties, a2- Describe the advantages and disadvantages of
preparation, structure activity relationship pharmaceutical liquid dosage forms.
‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

2
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

(SAR), toxicity and the modern methods of


analysis of various substances of chemical
and natural products of therapeutic potential
as well as the basic principle of drug
discovery, design and development
A4 Recognize the pharmaceutical dosage form a3- Recognize the different additives used in manufacturing
design and the quality control of of pharmaceutical solutions and colloids.
pharmaceutical formulations according to a4- Describe methods of preparation of pharmaceutical
GMP and pharmacopeia requirements to solutions and colloids.
support the pharmaceutical industries and a5- Discuss the method of evaluation of pharmaceutical
research. solutions and colloids.
Teaching And Assessment Methods For Achieving Learning Outcomes:
Alignment of Learning Outcomes of Knowledge and Understanding to Teaching and Assessment Methods:
Course Intended Learning Outcomes (CILOs) in Teaching strategies/methods Methods of assessment
Knowledge and Understanding to be used
completing this course, students will be able to: Lectures, brainstorming and Attendance, written exams,
group discussion reports, project and small
a1- Recognize the characteristics of different projects
pharmaceutical dosage forms and routes of
drug administration.
a2- Describe the advantages and disadvantages of
pharmaceutical liquid dosage form.
a3- Recognize the different additives used in
manufacturing of pharmaceutical solutions.
a4- Describe methods of preparation of
pharmaceutical solutions.
a5- Discuss the method of evaluation of
pharmaceutical solutions.

(B) Intellectual Skills:


Alignment of Course Intended Learning Outcomes (CILOs) to Program Intended Learning Outcomes (PILOs) in: Intellectual skills
Program Intended Learning Outcomes (Sub- Course Intended Learning Outcomes (CILOs) of
PILOs) in Intellectual skills Intellectual Skills
After completing this program, students will be able to: After completing this course, students will be able to:

‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

3
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

B1 Consolidate the chemical, biochemical and b1- Distinguish pharmaceutical liquid dosage forms.
physiological principles to construct the
pharmacophores of the structure and their
effect on the stability, pharmacokinetic and
pharmacodynamic profiles of the drug.
B3 Design different types of safe and effective b2- Determine the appropriate methods for preparation of
pharmaceutical dosage forms and develop solutions and colloids.
novel methods of qualitative and
quantitative analytical and biological
analysis for pharmaceutical and b3- Select the suitable method for evaluation of
pharmaceutical liquid dosage forms.
biopharmaceutical products that support
pharmaceutical research.
b4- Propose best approaches to solve the problems
encountered in formulation pharmaceutical liquid
dosage forms.

Teaching And Assessment Methods For Achieving Learning Outcomes:


Alignment of Learning Outcomes of Intellectual Skills to Teaching Methods and Assessment Methods:
Course Intended Learning Outcomes (CILOs) in Teaching strategies/methods Methods of assessment
Intellectual Skills. to be used
After completing this course, students will be able to: Lectures, solving problem, Written and oral exams and
b1- Distinguish pharmaceutical liquid dosage brainstorming and group small projects
forms. discussion
b2- Determine the appropriate methods for
preparation of solutions and colloids.
b3- Select the suitable method for evaluation of
pharmaceutical liquid dosage forms.

b4- Propose best approaches to solve the problems


encountered in formulation pharmaceutical
liquid dosage forms.

(C) Professional and Practical Skills:


Alignment of Course Intended Learning Outcomes (CILOs) to Program Intended Learning Outcomes (PILOs) in: Professional and
Practical Skills
Program Intended Learning Outcomes (Sub- Course Intended Learning Outcomes
PILOs) in Professional and Practical Skills (CILOs) in Professional and Practical Skills
After completing this program, students will be able to: After completing this course, students will be able to:

‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

4
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

C1- Operate different pharmaceutical equipments and c1- Select and practice different methods for
instruments and use emerging technologies in design, preparation of pharmaceutical liquid dosage
synthesis, pre-formulation, formulation, packaging, forms.
storage and analysis of pharmaceutical products
according to GLP, GSP and cGMP guidelines.
C3- Extract, isolate, purify, identify and formulate the natural c2- Formulate different pharmaceutical liquid
products and assure their rational use. dosage forms.

C5- Conduct research studies and utilize the results in c3- Label the different formulations of
different pharmaceutical fields. pharmaceutical liquid dosage forms.
c4- Evaluate the formulations of pharmaceutical
liquid dosage forms.
Teaching And Assessment Methods For Achieving Learning Outcomes:
Alignment of Learning Outcomes of Professional and Practical Skills to Teaching and Assessment Methods:
Course Intended Learning Outcomes (CILOs) in Teaching Methods of assessment
Professional and Practical Skills strategies/methods to
be used
After completing this course, students will be able to: Lectures, tutorials, Attendance, homework,
practical, discussion written, practical, oral
c1- Select and practice different methods for preparation of and brain storming exams, report, project
pharmaceutical liquid dosage forms. and observation.
c2- Formulate different pharmaceutical liquid dosage forms.
c3- Label the different formulations of pharmaceutical liquid
dosage forms.
c4- Evaluate the formulations of pharmaceutical liquid dosage
forms.

(D) General / Transferable Skills:


General and
Alignment of Course Intended Learning Outcomes (CILOs) to Program Intended Learning Outcomes (PILOs) in:
Transferable skills
Program Intended Learning Outcomes (PILOs) in Course Intended Learning Outcomes (CILOs) in
General / Transferable skills General / Transferable skills
After completing this program, students will be able to: After completing this course, students will be able to:
D2 Employ proper documentation and filing systems in d1- Implement writing and presentation skills
different pharmaceutical fields.
d2- Work independently or collaboratively to prepare
seminars/ presentations or write reports.

‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

5
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

D3 Develop financial, market management, writing, d3- Effectively use internet resources to search for up-to-
presentation and time management skills as well as date information to solve emerging problems.
creativity, critical thinking, problem solving and
decision making abilities.

Teaching And Assessment Methods For Achieving Learning Outcomes:


Alignment of Learning Outcomes of General and Transferable skills to Teaching and Assessment Methods:
Course Intended Learning Outcomes (CILOs) in Teaching strategies/methods Methods of assessment
General and Transferable Skills to be used
After completing this course, students will be able to: Lectures , practical, discussion Written, practical, oral
and brain storm exams, report, project and
d1- Implement writing and presentation skills. observation.

d2- Work independently or collaboratively to prepare


seminars/ presentations or write reports.

d3- Effectively use internet resources to search for up-to-


date information to solve emerging problems.

V. Course Content:
1 – Course Topics/Items:
a – Theoretical Aspect
Sub-topic List Number Contac
Order Topic List / Units CILOs (symbols)
of weeks t hours

1 Introduction to pharmaceutics a1, b1, c1, d1-3 Definition, types 1 2


Classification of dosage forms 2
2 and route of administration a1, b1, c1, d1-3 Excipients 1

Preformulation studies a3, a4, b2, b4, 2


3 Compatiblity, evaluation 1
d1-3
4 Galenical formulations a1, b1, d1-3 Dosage forms 1 2
Types of liquid pharmaceutical Definition, types, Advantages, 2
5
dosage forms
a1, a2, b1, d1-3 disadvantages,
1

6
Pharmaceutical solvents and
a1, a3, b1-2, d1-3
Definition, types, Advantages, 1 2
excipients disadvantages,

‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

6
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

7 Mid-term exam a1-4, b1, b2, b4 1 2


Definition, types, Advantages, 2 4
disadvantages, solvents,
Pharmaceutical Aqueous
excipients, methods of
8 Solutions a2-5, b1-4, d1-3 formulation and methods of
evaluation of pharmaceutical
aqueous solutions.
Definition, types, Advantages, 2 4
disadvantages, solvents,
Pharmaceutical non-aqueous
excipients, methods of
9 Solutions (elixirs, ) a2-5, b1-4, d1-3 formulation and methods of
evaluation of pharmaceutical
non-aqueous solutions.
Definition, types, Advantages,
disadvantages, solvents,
excipients, methods of 2 4
10 Pharmaceutical colloids a2-5, b1-4, d1-3 formulation and methods of
evaluation of pharmaceutical
colloids.
11 Final-term exam a1-5, b1-4 1 2
Number of Weeks /and Units Per Semester 16 32

b- Practical Aspect:
Number of Contact
Order Practical Tasks
CILOs (symbols) weeks hours

1.
Formulate, practice preparation, label and
c1-4, d1-3
3 6
evaluate topical aqueous solutions.
Formulate, practice preparation, label and
3 6
2.
evaluate oral aqueous solutions.
c1-4, d1-3

3. Mid-term exam c1-4 1 2

4.
Formulate, practice preparation, label and
c1-4, d1-3
3 6
evaluate topical non-aqueous solutions.
5.
Formulate, practice preparation, label and
c1-4, d1-3
3 6
evaluate oral non-aqueous solutions.
6.
Formulate, practice preparation, label and
c1-4, d1-3
2 4
evaluate colloidal solutions.
7. Final-term exam c1-4 1 2

‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

7
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

Number of Weeks /and Units Per Semester 16 32

I- a-Teaching strategies of the course:


Lecture method, Group Discussion, Problem solving sessions tutorials, brainstorming and Practical sessions.

b- Assessment Methods:

Oral Exam, Quizzes, Attendance, Participation, Short answers, reports, homework, and Written exam
Practical works, practical exam and practical reports.

VII. Assignments:
No. Assignments Aligned CILOs (symbols) Week Due Mark
1 Homework Assignments a1-4, b1-4, d1-3
Sporadic through the semester 10
2 Reports c1-4, d1-3

II- Schedule of Assessment Tasks for Students During the Semester:


Aligned Course
Proportion of
Week Learning
No. Assessment Method Mark Final
Due
Assessment Outcomes (CILOs
symbols)
Attendance, Participation and All 7% a2, a4,b1-2,d1-3
1. 10
quizzes Weeks
Sporadic 7% a1, a3, a5 b3-4, d1-3
Oral Tests and Homework- through
2. 10
assignments the
semester
All 10% c1-4
3. Attendance, Practical Reports 15
Weeks
4. Practical mid-semester exam 7th 15 10% c1-4
5. Theoretical mid-semester exam 7th 30 20% a1-4, b1, b2, b4

‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

8
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

6. Final Exam (theoretical) 16th 50 33% a1-5, b1-4


th
7. Final Exam (practical) 16 20 13% c1-4
Total 150 100%

VI. Students' Support:


Office Hours/week Other Procedures (if any)

2 hours per week

VII. Learning Resource (MLA style or APA style)s:


1- Required Textbook(s) ( maximum two )
1. Notes on Pharmaceutics prepared by the department staff.
2. Jones, D., 2008, ''FASTtrack Pharmaceutics- dosage form and design'' 1st edition, Pharmaceutical
Press, London.
3. Ansel; H.C., (2011) Pharmaceutical Dosage Forms and drug Delivery Systems’. 9th ed ,Lea &
Febiger; Philadelphia; London.
4. Aulton, M.E. (ed). (2013) Pharmaceutics, the design and manufacture of medicines. 4th edition,
Churchill Livingstone, Edinburgh.

2- Recommended Readings and Reference Materials

1. Loyd, V Allen J.,2013, Remington: The Science and Practice of Pharmacy 22nd edition,
Pharmaceutical Press, London.
2. Florence, A.T. and Attwood, D., 2006, ''Physicochemical principles of pharmacy'', 4th edition,
Pharmaceutical Press, London.
3. Banker, G.S.and Rhodes, C.T, (1999) Modern Pharmaceutics, 3rd edn. Marcel Dekker.

3- Electronic Materials and Web Sites etc.


www.pubmed.com
http://www.sciencedirect.com
4- Other Learning Material:
J. Pharm. Sci
Published articles related to the discussed topics
‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

9
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

I. Facilities Required:
- Well-equipped lecture halls with data show facilities, whiteboards,
1 - Accommodation: net connection, etc.
- Well-equipped laboratories with all required equipment and reagents.
2 - Computing resources: - Computer laboratory with internet facilities.

II. Course Improvement Processes:


1- Strategies for obtaining student feedback on effectiveness of teaching
 Student-based assessment of the effectiveness of teaching using a questionnaire designed by the
Quality Assurance Unit at the end of the semester.
 Meeting with students and faculty (once per semester).
2- Other strategies for evaluation of teaching by the instructor or by the department.
 Assessment of the course syllabus and contents by the teachers using a questionnaire designed by the
Quality Assurance Unit of the university at the end of the semester.
 Regular meeting and discussion of the course content between the Head of Department and the
teaching staff of the course (for theory and practice).

3- Processes for improvement of teaching.


 Revision of the course specification and its teaching strategies every three academic years after
consideration of all issues raised by the teachers and/or students during regular meetings and
discussions.
 Exploring any possible defects in the course that might be encountered by the teaching staff and
their mitigation in subsequent improved versions of course specification.
4- Processes for verifying standards of students' achievement
 Checking of a sample of students' work by an independent faculty member.
 Periodic exchange and check marking of a sample of students' assignments with a faculty member
from another institution.
 Adoption of scoring rubrics to assess the students' achievement (both for ongoing or summative
assessments).
 Regular follow-up of laboratory logbooks to assess the practical achievement of students.

‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

10
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

5- Procedures for periodically reviewing of course effectiveness and planning for improvement
 Student rating and feedback
 Peer rating and feedback
 Regular meeting of the Curriculum Committee of the faculty.
6- Course development plans
 Conducting regular workshops for the staff for improving their course specification skills.
 Regular revision of course specification and syllabus items.

VIII. Course Policies: (including plagiarism, academic honesty, attendance etc)

The University Regulations on academic misconduct will be strictly enforced. Please refer to -----------
1 Class Attendance:
 Attendance of all lectures and practical sessions is required. Unexcused absence exceeding 25% of the
lectures or practical sessions will disqualify the student from entering the final exam.
2 Tardy:
- Roll will be called in the very beginning of each lecture and practical class. Retardation for more than three
weeks without a reasonable excursion, the student involved shall not be allowed to attend the class any longer and
consequently shall be considered to be absent.

3 Exam Attendance/Punctuality:
 Exam attendance is obligatory unless being excused by the department and faculty.
 Absence from assignments or exams will be dealt with according to the general policy of the university.

4 Assignments & Projects:


 Assignments: Written and oral; Laboratory logbook signed by the responsible demonstrator.
 Projects: Not applicable.

5 Cheating:
 Punishment of cheating will be according to the general policy of the university in this respect.

6 Plagiarism:
 Plagiarism in written essays, reports, etc. is not accepted, and students who plagiarize the works of others
will be punished according to the general policy of the university.

7 Other policies:
‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

11
‫‪Republic of Yemen‬‬
‫‪Minster of Higher Education‬‬ ‫الجوهىريت اليونيت‬
‫‪and Scientific Research‬‬ ‫وزارة التعلين العالي والبحث العلوي‬
‫‪Sana’a University‬‬ ‫جاهعت ‪ -‬صنعاء‬
‫‪Faculty of Pharmacy‬‬ ‫كليت الصيدلت‬
‫‪Quality Assurance Unit‬‬ ‫وحدة ضواى الجىدة‬

‫‪‬‬ ‫‪General policies of the Students' Affairs of the University and the Quality Assurance Unit.‬‬

‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ا‪.‬د‪ .‬القاضن دمحم عباش‬ ‫ا‪.‬م‪.‬د‪ .‬هدي العواد‬ ‫ا‪.‬د‪.‬احود ضباتي‬ ‫ا‪.‬د‪.‬احود ضباتي‬ ‫ا‪.‬د‪ .‬عبدالىلي أحود ضيف ا‪.‬د‪ .‬هحوىد البريهي‬

‫‪12‬‬
‫‪Republic of Yemen‬‬
‫‪Minster of Higher Education‬‬ ‫الجوهىريت اليونيت‬
‫‪and Scientific Research‬‬ ‫وزارة التعلين العالي والبحث العلوي‬
‫‪Sana’a University‬‬ ‫جاهعت ‪ -‬صنعاء‬
‫‪Faculty of Pharmacy‬‬ ‫كليت الصيدلت‬
‫‪Quality Assurance Unit‬‬ ‫وحدة ضواى الجىدة‬

‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ا‪.‬د‪ .‬القاضن دمحم عباش‬ ‫ا‪.‬م‪.‬د‪ .‬هدي العواد‬ ‫ا‪.‬د‪.‬احود ضباتي‬ ‫ا‪.‬د‪.‬احود ضباتي‬ ‫ا‪.‬د‪ .‬عبدالىلي أحود ضيف ا‪.‬د‪ .‬هحوىد البريهي‬

‫‪13‬‬
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

Course Plan of Pharmaceutics I

I. - Information about Faculty Member Responsible for the Course:


Prof. Dr. Abdulwali Office Hours
Name of Faculty Member Ahmed Saif

Location & Telephone No. SAT SUN MON TUE WED THU

E-mail

II. Course Identification and General Information:


Course Title:
1- Pharmaceutics I
2- Course Number & Code: Ph234
C.H
Total
3- Credit hours: 3hrs Th. Seminar Pr. F. Tr.
2 - 1 3
4- Study level/year at which this course is offered: Second year/First semester
5- Pre –requisite (if any): Physical Pharmacy
6- Co –requisite (if any):
7- Program (s) in which the course is offered Bachelor of Pharmacy
8- Language of teaching the course: English
9- System of Study: Semesters
10- Mode of delivery: Regular
11- Location of teaching the course: Faculty of Pharmacy-Sana’a University

VIII. Course description:


This course aims to provide the students with the basic knowledge of pharmaceutics and different pharmaceutical
dosage forms and the route of drug administration. It focused on the advantages and disadvantages, additives
methods of formulation and methods of evaluation of solutions and colloids as pharmaceutical liquid dosage forms.

‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

14
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

IX. Intended learning outcomes (ILOs) of the course:


At the end of this course, the students will be able to:

17. Recognize the characteristics of different pharmaceutical dosage forms and routes of drug administration.
18. Describe the advantages and disadvantages of pharmaceutical liquid dosage forms.
19. Recognize the different additives used in manufacturing of pharmaceutical solutions and colloids.
20. Describe methods of preparation of pharmaceutical solutions and colloids.
21. Discuss the method of evaluation of pharmaceutical solutions and colloids.
22. Distinguish pharmaceutical liquid dosage forms.
23. Determine the appropriate methods for preparation of solutions and colloids.
24. Select the suitable method for evaluation of pharmaceutical liquid dosage forms.
25. Propose best approaches to solve the problems encountered in formulation pharmaceutical liquid dosage
forms.
26. Select and practice different methods for preparation of pharmaceutical liquid dosage forms.
27. Formulate different pharmaceutical liquid dosage forms.
28. Label the different formulations of pharmaceutical liquid dosage forms.
29. Evaluate the formulations of pharmaceutical liquid dosage forms.
30. Implement writing and presentation skills.
31. Work independently or collaboratively to prepare seminars/ presentations or write reports.
32. Effectively use internet resources to search for up-to-date information to solve emerging problems.

X. Course Content:
1 – Course Topics/Items:
a – Theoretical Aspect
Sub-topic List Number Contac
Order Topic List / Units CILOs (symbols)
of weeks t hours

1 Introduction to pharmaceutics a1, b1, c1, d1-3 Definition, types 1 2


Classification of dosage forms 2
2 and route of administration a1, b1, c1, d1-3 Excipients 1

Preformulation studies a3, a4, b2, b4, 2


3 Compatiblity, evaluation 1
d1-3
4 Galenical formulations a1, b1, d1-3 Dosage forms 1 2

‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

15
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

Types of liquid pharmaceutical Definition, types, Advantages, 2


5
dosage forms
a1, a2, b1, d1-3 disadvantages,
1

6
Pharmaceutical solvents and
a1, a3, b1-2, d1-3
Definition, types, Advantages, 1 2
excipients disadvantages,
7 Mid-term exam a1-4, b1, b2, b4 1 2
Definition, types, Advantages, 2 4
disadvantages, solvents,
Pharmaceutical Aqueous
excipients, methods of
8 Solutions a2-5, b1-4, d1-3 formulation and methods of
evaluation of pharmaceutical
aqueous solutions.
Definition, types, Advantages, 2 4
disadvantages, solvents,
Pharmaceutical non-aqueous
excipients, methods of
9 Solutions (elixirs, ) a2-5, b1-4, d1-3 formulation and methods of
evaluation of pharmaceutical
non-aqueous solutions.
Definition, types, Advantages,
disadvantages, solvents,
excipients, methods of 2 4
10 Pharmaceutical colloids a2-5, b1-4, d1-3 formulation and methods of
evaluation of pharmaceutical
colloids.
11 Final-term exam a1-5, b1-4 1 2
Number of Weeks /and Units Per Semester 16 32

b- Practical Aspect:
Number of Contact
Order Practical Tasks
CILOs (symbols) weeks hours

8.
Formulate, practice preparation, label and
c1-4, d1-3
3 6
evaluate topical aqueous solutions.
Formulate, practice preparation, label and
3 6
9.
evaluate oral aqueous solutions.
c1-4, d1-3

10. Mid-term exam c1-4 1 2

11.
Formulate, practice preparation, label and
c1-4, d1-3
3 6
evaluate topical non-aqueous solutions.
12.
Formulate, practice preparation, label and
c1-4, d1-3
3 6
evaluate oral non-aqueous solutions.
‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

16
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

13.
Formulate, practice preparation, label and
c1-4, d1-3
2 4
evaluate colloidal solutions.
14. Final-term exam c1-4 1 2
Number of Weeks /and Units Per Semester 16 32

VI- a-Teaching strategies of the course:


Lecture method, Group Discussion, Problem solving sessions tutorials, brainstorming and Practical sessions.

b- Assessment Methods:

Oral Exam, Quizzes, Attendance, Participation, Short answers, reports, homework, and Written exam
Practical works, practical exam and practical reports.

VII. Assignments:
No. Assignments Aligned CILOs (symbols) Week Due Mark
1 Homework Assignments a1-5, b1-4, d1-3
Sporadic through the semester 10
2 Reports c1-4, d1-3

VIII- Schedule of Assessment Tasks for Students During the Semester:


Aligned Course
Proportion of
Week Learning
No. Assessment Method Mark Final
Due
Assessment Outcomes (CILOs
symbols)
Attendance, Participation and All 7% a2, a4,b1-2,d1-3
8. 10
quizzes Weeks
Sporadic 7% a1, a3, a5 b3-4, d1-3
Oral Tests and Homework- through
9. 10
assignments the
semester
All 10% c1-4
10. Attendance, Practical Reports 15
Weeks
‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

17
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

11. Practical mid-semester exam 7th 15 10% c1-4


12. Theoretical mid-semester exam 7th 30 20% a1-4, b1, b2, b4
13. Final Exam (theoretical) 16th 50 33% a1-5, b1-4
14. Final Exam (practical) 16th 20 13% c1-4
Total 150 100%

IX. Students' Support:


Office Hours/week Other Procedures (if any)

2 hours per week

X. Learning Resource (MLA style or APA style)s:


5- Required Textbook(s) ( maximum two )
5. Notes on Pharmaceutics prepared by the department staff.
6. Jones, D., 2008, ''FASTtrack Pharmaceutics- dosage form and design'' 1st edition, Pharmaceutical
Press, London.
7. Ansel; H.C., (2011) Pharmaceutical Dosage Forms and drug Delivery Systems’. 9th ed ,Lea &
Febiger; Philadelphia; London.
8. Aulton, M.E. (ed). (2013) Pharmaceutics, the design and manufacture of medicines. 4th edition,
Churchill Livingstone, Edinburgh.

6- Recommended Readings and Reference Materials

4. Loyd, V Allen J.,2013, Remington: The Science and Practice of Pharmacy 22nd edition,
Pharmaceutical Press, London.
5. Florence, A.T. and Attwood, D., 2006, ''Physicochemical principles of pharmacy'', 4th edition,
Pharmaceutical Press, London.
6. Banker, G.S.and Rhodes, C.T, (1999) Modern Pharmaceutics, 3rd edn. Marcel Dekker.

7- Electronic Materials and Web Sites etc.


www.pubmed.com
http://www.sciencedirect.com
‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

18
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

8- Other Learning Material:


J. Pharm. Sci
Published articles related to the discussed topics

XI. Facilities Required:


- Well-equipped lecture halls with data show facilities, whiteboards,
1 - Accommodation: net connection, etc.
- Well-equipped laboratories with all required equipment and reagents.
3 - Computing resources: - Computer laboratory with internet facilities.

XII. Course Improvement Processes:


6- Strategies for obtaining student feedback on effectiveness of teaching
 Student-based assessment of the effectiveness of teaching using a questionnaire designed by the
Quality Assurance Unit at the end of the semester.
 Meeting with students and faculty (once per semester).
7- Other strategies for evaluation of teaching by the instructor or by the department.
 Assessment of the course syllabus and contents by the teachers using a questionnaire designed by the
Quality Assurance Unit of the university at the end of the semester.
 Regular meeting and discussion of the course content between the Head of Department and the
teaching staff of the course (for theory and practice).

8- Processes for improvement of teaching.


 Revision of the course specification and its teaching strategies every three academic years after
consideration of all issues raised by the teachers and/or students during regular meetings and
discussions.
 Exploring any possible defects in the course that might be encountered by the teaching staff and
their mitigation in subsequent improved versions of course specification.
9- Processes for verifying standards of students' achievement
 Checking of a sample of students' work by an independent faculty member.
 Periodic exchange and check marking of a sample of students' assignments with a faculty member
from another institution.
 Adoption of scoring rubrics to assess the students' achievement (both for ongoing or summative
‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

19
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

assessments).
 Regular follow-up of laboratory logbooks to assess the practical achievement of students.
10- Procedures for periodically reviewing of course effectiveness and planning for improvement
 Student rating and feedback
 Peer rating and feedback
 Regular meeting of the Curriculum Committee of the faculty.
6- Course development plans
 Conducting regular workshops for the staff for improving their course specification skills.
 Regular revision of course specification and syllabus items.

XIII. Course Policies: (including plagiarism, academic honesty, attendance etc)

The University Regulations on academic misconduct will be strictly enforced. Please refer to -----------
1 Class Attendance:
 Attendance of all lectures and practical sessions is required. Unexcused absence exceeding 25% of the
lectures or practical sessions will disqualify the student from entering the final exam.
2 Tardy:
- Roll will be called in the very beginning of each lecture and practical class. Retardation for more than three
weeks without a reasonable excursion, the student involved shall not be allowed to attend the class any longer and
consequently shall be considered to be absent.

3 Exam Attendance/Punctuality:
 Exam attendance is obligatory unless being excused by the department and faculty.
 Absence from assignments or exams will be dealt with according to the general policy of the university.

4 Assignments & Projects:


 Assignments: Written and oral; Laboratory logbook signed by the responsible demonstrator.
 Projects: Not applicable.

5 Cheating:
 Punishment of cheating will be according to the general policy of the university in this respect.

6 Plagiarism:
 Plagiarism in written essays, reports, etc. is not accepted, and students who plagiarize the works of others
‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

20
Republic of Yemen
Minster of Higher Education ‫الجوهىريت اليونيت‬
and Scientific Research ‫وزارة التعلين العالي والبحث العلوي‬
Sana’a University ‫ صنعاء‬- ‫جاهعت‬
Faculty of Pharmacy ‫كليت الصيدلت‬
Quality Assurance Unit ‫وحدة ضواى الجىدة‬

will be punished according to the general policy of the university.

7 Other policies:
 General policies of the Students' Affairs of the University and the Quality Assurance Unit.

‫رئيص الجاهعت‬ ‫عويدة هركس التطىير وضواى الجىدة‬ ‫عويد الكليت‬ ‫رئيص القطن‬ ‫نائب العويد لشؤوى الجىدة‬ ‫الو ىصف‬
‫ القاضن دمحم عباش‬.‫د‬.‫ا‬ ‫ هدي العواد‬.‫د‬.‫م‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫احود ضباتي‬.‫د‬.‫ا‬ ‫ هحوىد البريهي‬.‫د‬.‫ عبدالىلي أحود ضيف ا‬.‫د‬.‫ا‬

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