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    ZAK +2 Revision Test - 4

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    ZAK +2 Revision Test - 4

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    ZAK +2 Revision Test - 4

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    ZAK TEST SERIES PLUS TWO – 2022

    Molecular basis of inheritance


    Score: 30
    Time: 1 hr
    PART I
    A. Answer any three questions from 1 to 4. Each carries 1 score. (3x1=3)
    1. A very simple but famous double Helix model for the structure of DNA is
    proposed by
    a. Maurice Wilkins and Rosalind Franklin b. Friedrich Meischer
    c. Erwin Chargaff d. James Watson and Francis Crick
    2. Nitrogen base -----A----- is common for both DNA and RNA and thymine is
    present in DNA. ---B------ is present in RNA at the place of Thymine.
    (Name A and B)
    3. Lac-operon is an example for inducible operon. Here inducer is ---------
    4. Name two organisms whose genetic material is RNA.
    B. Answer all questions from 5 to 6. Each carries 1 score. (2x1=2)
    5. A typical nucleosome contains ------ bp of DNA helix.
    a. 100 b. 200 c. 75 d. 10
    6. Two major steps of protein synthesis are A and B. Name A and B
    PART II
    A. Answer any two questions from 7 to 9. Each carries 2 scores. (2x2=4)
    7. Observe the given diagram

    a) Name the structure.


    b) Mention A,B and C in the diagram.
    8. The sequence of the coding strand in a transcription unit is written as follows:
    5'-ATGCATGCATGCATGCATGCATGCATGC-3'
    Write down the sequence of mRNA.
    9. Expand the following a) HGP b) BAC
    B. Answer any two questions from 10 to 13. Each carries 2 scores. (2x2=4)
    10. Write down a) Initiation codon b) Termination codons
    11.

    a) Name a ,b and c b) Who proposed this?

    12. Differentiate the terms Euchromatin and Heterochromatin.


    13. Write down the functions of following –
    a) m-RNA b) t- RNA
    PART III
    A. Answer any three questions from 14 to 17. Each carries 3 scores. (3x3=9)
    14. A + Injected to mice → Mice live
    S strain + Injected to mice → B
    Heat killed S strain + Injected to mice → C
    {D + R strain (live)} + Injected to mouse → Mice die
    a) Mention A,B, C and D in the above expt.
    b) Who has done this expt? Write down the aim of this experiment.
    c) Name the bacteria used in this expt.
    15. a) Identify the given schematic structure (1)

    b) Name A,B and C (1)


    c) Differentiate the terms exons and introns (1)
    .
    16. Replication fork formed during DNA- replication is given.

    a) Compare DNA replication in A and B.


    b) What is meant by okazaki fragments.
    c) Write down the role of enzymes DNA polymerase and DNA ligase in DNA
    replication.
    17. a) Steps of DNA finger printing is given. Arrange them in correct order.(2)
    i) Isolation of DNA
    ii)Transferring (blotting) of separated DNA fragments to synthetic membranes,
    such as nitrocellulose or nylon
    iii) Detection of hybridised DNA fragments by autoradiography
    iv) Digestion of DNA by restriction endonucleases
    v) Separation of DNA fragments by electrophoresis
    vi) Hybridisation using labelled VNTR probe
    b) Name the scientist who initially developed the DNA fingerprinting. Write down
    two benefits of DNA fingerprinting. (1)
    B. Answer the following. It carries 3 score. (1x3=3)
    18. Genetic code is nearly universal. Write down the other features of genetic code.
    PART IV
    Answer any one questions from 19 to 20. Each carries 5 scores. (1x5=5)
    19. Diagram shows the three steps of transcription in prokaryotes.

    a) Name the steps A,B and C (1)


    b) Write down the role of sigma factor ,RNA polymerase and rho factor in
    transcription.(2)
    c) Mention two differences between prokaryotic transcription and eukaryotic
    transcription.(2)
    20. Two stages of Lac operon is given

    a) Identify the different stages of Lac operon – (i) and (ii) (1)
    b) Mention the roles of operator and promoter in an operon. (2)
    c) Name the enzymes A,B and C (1)
    d) Write down the functions of A and B (1)

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