Anaphy Lec
Anaphy Lec
Anaphy Lec
MODULE 10
Ascending Tracts – transmit information via action potentials
TYPES OF ASCENDING TRACTS
1. Spinothalamic – pain, temperature, light touch
2. Dorsal Column – touch, deep pressure, vibration
3. Spinocerebellar – proprioception to the cerebellum
SENSORY AREAS OF CEREBRAL CORTEX
1. Primary Sensory Areas – where sensations are perceived
• Association Areas – process of recognition
2. General Sensory Area – receives information from sensory fibers
MOTOR NEURONS IN VOLUNTARY MOVEMENTS
1. Upper Motor Neuron – have cell bodies in cerebral cortex
2. Lower Motor Neurons – have cell bodies in spinal cord
AREAS OF CEREBRAL CORTEX
1. Primary Motor Cortex – control voluntary motor movements
2. Premotor Area – motor functions are organized before initiation
3. Prefrontal Area – regulation of emotional behavior
Descending Tracts – control different types of movement
• Direct Pathway – extends upper motor neurons in cerebral cortex
° Lateral Corticospinal – muscle tone and skilled movements
° Anterior Corticospinal – movement of trunk muscles
• Indirect Pathway – no direct connection exist between cortical
and spinal neurons
° Rubrospinal – movement coordination
° Reticulospinal – posture adjustment
° Vestibulospinal – posture and balance
° Tectospinal – movement in response to visual reflexes
Basal Nuclei – vital in planning motor movements
FEEDBACK LOOPS
• Stimulatory Circuit – initiate an action
• Inhibitory Circuit – inhibit random movements
Commissures – share the received sensory information
• Corpus Callosum – nerve tracts at the base of longitudinal fissure
° Right Cerebral Hemisphere – receive sensory input in the left half
of the body
• Left Cerebral Hemisphere – receives input in the right half of the
body
Speech – hast two cortical areas
1. Sensory Speech – functions in understanding and formulating
coherent speech
2. Motor Speech – controls movement necessary for speech
Electroencephalogram – electrodes place on a person’s scalp to
record brain’s electrical activity
TYPES OF BRAIN WAVE
• Alpha Waves – normal person is awake but in a quiet resting rate
• Beta Waves – occur during intense mental activity
• Delta Waves – occur during sleep, in infants and patients with
severe brain disorder
• Theta Waves – common in children, may occur in adults
THREE STAGES OF MEMORY
1. Working Memory – task associated memory
2. Short Term Memory – can retain information for few minutes
• Consolidation – gradual process of stronger synaptic connections
3. Long Term Memory – can store information or become
permanent
• Declarative Memory – retention of facts
• Procedural Memory – development of motor skills; small amount
of memory is lost over time
Memory Engrams – long-term retention of given piece of
information
Limbic system – influences long-term declarative memory
Meninges – protective wrap around brain
TYPES OF MENINGES
1. Dura Mater – adheres tightly to cranial bone
• Dural Folds – hold the brain in place within skull
• Dural Venous Sinuses – collect blood from the small veins of brain
Epidural Space – space of vertebral canal
2. Arachnoid Mater – wispy second layer
• Subdural Space – space between dura and arachnoid mater
3. Pia Mater – tightly bound to surface of brain
• Subarachnoid Space – space between arachnoid and pia mater
Ventricle – fluid filled cavities of CNS
• Lateral Ventricle – cavity within cerebral hemisphere
• Third Ventricle – cavity located in diencephalon
• Cerebral Aqueduct – connect third and fourth ventricle
• Fourth Ventricle – located at the base of cerebellum
Cerebrospinal Fluid – provides a cushion around CNS
Arachnoid Granulation – arachnoid tissue that penetrates the
sagittal sinus
Cranial Nerves – have 12 pairs divided by two categories
• Sensory Function – divide into special senses and more general
senses
• Motor Function – subdivided into somatic and parasympathetic
motor
ANS – carry action potentials from CNS to periphery
STRUCTURE
• Preganglionic Neuron – first neuron that innervates from CNS
• Postganglionic Neuron – second neuron that extends to effector
organ
• Autonomic Ganglia – preganglionic neurons synapse with
postganglionic neuron
DIVISIONS OF ANS
1. Sympathetic
2. Parasympathetic
Enteric Nervous System – consist of plexuses within the wall of
digestive tract
MODULE 2
Cells – basic unit of life
Organelles – specialized structures in cells
Cytoplasm – jelly substance that holds organelles
FUNCTIONS OF CELL
• Cell metabolism and energy use
• Synthesis of molecules
• Communication
• Reproduction and inheritance
Cell Membrane – outermost component that forms a selective
barrier
MOLECULAR STRUCTURE
Major Molecules
• Phospholipids – form a double layer which contains 2 regions:
Polar (head) and Non-polar (tail)
• Protein – float among phospholipid molecules as membrane
channels
Other Components
• Cholesterol – limit the amount of phospholipid
• Carbohydrates – modify the functions of CHON
ORGANELLES AND THEIR FUNCTIONS
• Nucleus – site of RNA synthesis
• Ribosomes – site of protein synthesis
• Rough E.R – has ribosomes
• Smooth E.R – site of lipid synthesis
• Golgi Apparatus – modifies CHON structure
• Secretory Vesicle – contains materials produced in cell
• Lysosome – digest material taken into the cell
• Peroxisome – breaks down fatty acids in cell
• Mitochondria – major site of ATP synthesis
• Microtubule – supports cytoplasm
• Centrioles – facilitate the movement of chromosomes
• Cilia – move substances over surfaces of certain cells
• Flagella – proper sperm cells
• Microvilli – increase surface area of certain cells
MOVEMENT THROUGH CELL MEMBRANE
• Passive Membrane Transport – does not require the cell to
expend energy
• Active Membrane Transport – require the cell to expend energy
• Diffusion – movement of solute from higher concentration to
lower concentration
• Concentration Gradient – concentration of solute minus the
concentration of that solute
• Osmosis – diffusion of water across permeable membrane
• Facilitated Diffusion – moves substances from higher to lower
concentration; does not require ATP
• Carrier-Mediated Transport – movement of substance across
membrane by carrier molecule
• Active Transport – substance from lower to higher and requires
ATP
• Secondary Active Transport – use the energy of one substance to
move another substance
Endocytosis – movement of materials into cells by formation of
vesicle
• Receptor Mediated Endocytosis – involves cell receptors
• Phagocytosis – movement of solid material into cells (cell-eating)
• Pinocytosis – ingested is much smaller (cell-drinking)
Exocytosis – secretion of materials from cells
Cytoskeleton – cells framework that enables cell to change shape
TYPES OF CYTOSKELETON
1. Microtubules – largest diameter cytoskeleton
2. Intermediate Filaments – medium diameter cytoskeleton
3. Microfilaments – smallest diameter of cytoskeleton
DNA – double helix nucleus
• Cytosine – Guanine
• Thymine – Adenine
Gene Expression – DNA direct protein synthesis; has two stages
1. Transcription – DNA is read
2. Translation – mRNA is converted into amino acids
Cell Cycle – events that produce new cells; two phases:
1. Interphase – DNA replicates
2. Cell Division – formation of two daughter cells
a. Prophase – two chromatids joined at centromere
b. Metaphase – chromosomes align at the center of cell
c. Anaphase – chromatids separate at centromere
d. Telophase – two nuclei assume their normal structure
Differentiation – cells developed specialized structures
Apoptosis – aka programmed cell death
MODULE 1
Anatomy – study of the structures of the body
Physiology – study of the functions and processes of the body
LEVELS OF ORGANIZATION FOR HUMAN BODY
1. Chemical – involves how atom interact
2. Cell – basic unit of life
3. Tissue – group of similar cells
4. Organ – composed of two or more tissue types
5. Organ system – group of organs classified as unit
6. Organism – complex of organ system
ORGANS OF HUMAN BODY
1. Integumentary – regulates temperature in skin
2. Skeletal – allows body movements
3. Muscular – maintains posture
4. Nervous – detect sensations and control movements
5. Endocrine – influences metabolism
6. Cardiovascular – transport nutrients
7. Lymphatic – removes foreign substance
8. Digestive – performs mechanical and and chemical processes of
digestion
9. Respiratory – exchanges oxygen and carbon dioxide
10. Urinary – removes waste products
11. Reproductive – produces oocytes and sperm cells
ESSENTIAL CHARACTERISTICS OF LIFE
1. Organization – relationship of many individual parts of an
organism
2. Metabolism · ability to use energy to perform vital functions
3. Responsiveness – ability of an organism to sense changes
4. Growth – refers to increase in size of organism
5. Development – changes an organism undergoes
6. Reproduction – formation of new cells
Homeostasis – condition in which body functions are maintained
• Negative Feedback Mechanism – regulates most system of the
body
• Positive Feedback Mechanism – when initial stimulus further
stimulates the response
Anatomical Position – person standing upright
Directional Terms – refer to anatomical position
• Right – body’s right side
• Left – body’s left side
• Inferior – below
• Superior – above
• Anterior – front of the body
• Posterior – back of the body
• Dorsal – back
• Ventral – belly
• Proximal – Closer
• Distal – farther
• Lateral – away from the midline of the body
• Medial – toward the midline of the body
• Superficial – on the surface
• Deep – away from the surface
PLANES
• Sagittal – vertically through the body
• Median – passes through the midline of the body
• Transverse – runs parallel
• Frontal – runs vertically
SECTIONS
• Longitudinal – cut along the length of organ
• Cross Section – cut completely through an organ
• Oblique – cut is made diagonally
TRUNK CAVITIES
• Thoracic Cavity – surrounded by rib cage
• Abdominal Cavity – bounded by abdominal muscles
• Pelvic Cavity – small space enclosed by the bones of pelvis
SEROUS MEMBRANE
• Visceral – contact with organs
• Parietal – contact with the walls of cavity