Diagnostic Agents
Diagnostic Agents
Diagnostic Agents
INTRODUCTION
Diagnostic agents are the substances used to examine the body in order to detect
impairment of its normal functions. Usually these agents find no other use in medicine.
Diagnostic agents are divided according to the use as
CLASSIFICATION
CH3(CH2)2COHN CH2.CH.COONa
Ι Ι
Sodium -3- butyramido - α - ethyl -2,4-6 - triiodo
xiii) hydrocinnamate
N - CH2 - CH - COOH
CH3
Ι Ι
NH2
3 - [Acetyl - (3 - amino - 2,4,6 - triiodophenyl)
xiv) amino] - 2- methyl propanoic acid
Gastric Function
Congo Red
NH2
NH2
N=N N=N
SO3Na SO3Na
3,3' - [(Biphenyl) - 4,4' - diyl bis (azo)] bisamino - 1 - napthalene sulphonic acid
Liver Function
A. Indocyanine Green
CH3 CH3
H3C CH3
N N
SO3(CH2)4
(CH2)4 SO3 Na
Use: It is used to determine cardiac output, hepatic function and liver blood flow. It is also used
to measure plasma volume and regional blood flow in various organs including kidney, eye and
lungs.
NaO O O
COONa
Use: It is used in ophthalmic practice for detecting corneal lesions and foreign bodies in the eyes.
Pancreatic Function
Bentiromide
NH - CO