Chapter wise NPP of Selected Question (Neet:2024-2025)

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1. A very important feature of respiration is that –

(a) It liberates energy (b) It provides O2
(c) Utilize CO2 (d) Synthesize complex compounds
2. What is the function of molecular oxygen in cellular respiration?
(a) It causes the breakdown of citric acid.
(b) To combine with glucose to produce carbon dioxide.
(c) To combine with carbon from organic molecules to produce carbon dioxide.
(d) To combine with hydrogen from organic molecules to produce water.
3. Sugars are not as good as fats as a source of energy for cellular respiration, because sugars
(a) produce toxic amino groups when broken down.
(b) contain more hydrogen.
(c) usually bypass glycolysis and the Krebs cycle.
(d) contain fewer hydrogen atoms and electrons.
4. For bacteria to continue growing rapidly when they are shifted from an environment containing O2 to an
anaerobic environment, they must
(a) produce more ATP per mole of glucose during glycolysis.
(b) produce ATP during oxidation of glucose.
(c) increase the rate of glycolysis.
(d) increase the rate of TCA cycle.
5. The major reason that glycolysis is not as energy productive as respiration is that
(a) NAD+ is regenerated by alcohol or lactate production, without the high-energy electrons passing through the
electron transport chain.
(b) it is the pathway common to fermentation and respiration.
(c) it does not take place in a specialized membrane-bound organelle.
(d) pyruvate is more reduced than CO2; it still contains much of the energy from glucose.
6. Protein is used as respiratory substrate only when
(a) Carbohydrates are absent (b) Fats are absent
(c) Both carbohydrates and fats are exhausted (d) Fats and carbohydrates are abundant
7. The expressions given below shows the summary equations.

8. Conversion of pyruvic acid into ethyl alcohol is mediated by -

(a) Phosphatase (b) Dehydrogenase
(c) Decarboxylase & dehydrogenase (d) Catalase
9. Which enzyme break downs the fructose-1,6-diphosphate?
(a) Hexokinase (b) Phosphatase
(c) Aldolase (d) None of these
10. Pyruvate (pyruvic) dehydrogenase is used in converting
(a) pyruvate to glucose (b) glucose to pyruvate
(c) pyruvic acid to lactic acid (d) pyruvate to acetyl coA
11. Last electron receptor in respiration is
(a) CO2 (b) O2
(c) H2 (d) NADH
12. When 2-pyruvic acids forms two lactic acid by anaerobic respiration then –
(a) One ATP is lost (b) 3 ATP is lost
(c) 6 ATP is lost (d) None of these
13. Inside an active mitochondrion, most electrons follow which pathway ?

14. Which of the following is coenzyme-II ?

(a) NAD (b) NADP
(c) FAD (d) None of these
15. Excess of ATP inhibits the enzyme -
(a) Phosphofructokinase (b) Hexokinase
(c) Aldolase (Lyases) (d) Pyruvate decarboxylase
16. During the formation of bread, it becomes porous due to release of CO2 by the action of :
(a) Yeast (b) Bacterial
(c) Virus (d) Protozoans
17. Respiration is
(a) anabolic + exergonic (b) catabolic + exergonic
(c) catabolic + endergonic (d) anabolic + endergonic
18. Which one is the product of aerobic respiration ?
(a) Malic acid (b) Ethyl alcohol
(c) Lactic acid (d) Pyruvic acid
19. In glycolysis, during oxidation electrons are removed by–
(a) Molecular oxygen (b) ATP
(c) Glyceraldehyde (d) NAD+
20. How many moles of carbon dioxide are produced by the complete oxidation of 1 mole of pyruvate?
(a) 1 (b) 2
(c) 3 (d) 4
21. During the early stages of alcoholic fermentation there is a high rate of growth of yeast. After some time the rate
decreases. Which of the following conditions in the culture medium is least likely to have caused this?
(a) Depletion of glucose (b) Depletion of oxygen
(c) Depletion of mineral salts (d) Accumulation of waste products
22. Certain organism are allowed to respire anaerobically for some time. If they are transferred to an oxygen
containing medium, the rate of aerobic respiration of these organisms is always faster as compared to the rate of
respiration of organisms which are given O2 since the beginning. This might be due to one of the following reasons.
(a) Due to faster rate of oxidation, the end products accumulate in the aerobic organisms reduces the rate of its
respiration
(b) In anaerobically respiring animals there are extra enzymes to increase the rate of the oxidation
(c) In anaerobically respiring animals the end product produced is common with that of aerobic respiration and
therefore the rate of oxidation is hastened
(d) In aerobically respiring organisms an intermediate product of anaerobic respiration is further oxidized.
23. When protein molecules are used as fuel for aerobic cellular respiration, _____ are produced as waste.
(a) amino groups (b) fatty acids
(c) sugar molecules (d) molecules of lactic acid
24. Why is glycolysis considered one of the first metabolic pathways to have evolved ?
(a) It relies on fermentation, which is characteristic of the archaebacteria and eubacteria.
(b) It produces much less ATP than does the electron transport chain and chemiosmosis.
(c) It relies totally on enzymes that are produced by free ribosomes, and bacteria have only free ribosomes and no
bound ribosomes.
(d) It is nearly universal, is located in the cytosol, and does not involve O2.
25. In which of the following reaction of glycolysis, a molecule of water is removed from the substrate ?

26. Conversion of fructose–6–phosphate to fructose 1, 6-diphosphate is catalysed by

(a) Phosphofructose kinase (b) Aldolase
(c) Hexokinase (d) None of these
27. Acetyl CoA is produced from pyruvate by
(a) oxidative decarboxylation (b) oxidative photophosphorylation
(c) oxidative hydrogenation (d) oxidative photorespiration
28. The carrier which transfer the electrons in electron transport system is
(a) phytochrome (b) cytochrome
(c) quantasomes (d) fucoxanthin
29. Which group of the following scientists discovered the EMP pathway of glycolysis?
(a) Embden, Meyerhof and Parnas (b) Emerson, Hoffman and Peterson
(c) Embden, Morrison and Pitcher (d) Avery, McLeod and McCarthy
30. The formation of Acetyl Co-A from pyruvic acid is the result of its –
(a) Reduction (b) Dehydration
(c) Phosphorylation (d) Oxidative decarboxylation
31. Oxidation of one molecule of glucose in aerobic respiration results in the formation of –
(a) 36 ATP molecules (b) 38 ATP molecules
(c) 3 ATP molecules (d) 15 ATP molecules
32. Which of the following reactions is incorrectly paired with its location ?
(a) ATP synthesis/inner membrane of the mitochondrion.
(b) Fermentation/cell cytosol
(c) Glycolysis/cell cytosol
(d) Krebs cycle/cristae of mitochondrion
33. Glucose, made from six radioactively labeled carbon atoms, is fed to yeast cells in the absence of oxygen. How
many molecules of radioactive alcohol (C2H5OH) are formed from each molecule of glucose ?
(a) 0 (b) 1
(c) 2 (d) 3
34. Enzyme cytochrome oxidase can be inhibited by –
(a) Iodoacetate (b) Azides & Cyanides
(c) Oligonlycins (d) Dinitrophenol
35. Number of oxygen atoms required for aerobic oxidation of pyruvate –
(a) 6 (b) 8
(c) 10 (d) 12
36. Which of the following conversions represents a reduction reaction ?

37. Link between glycolysis & TCA cycle is –

(a) Pyruvic acid (b) Acetyl Co-A
(c) Citric acid (d) None of these
38. Acceptor of acetyl Co-A in Kreb's-cycle is
(a) Malic acid (b) Fumaric acid
(c) a-ketoglutaric acid (d) Oxalo acetic acid
39. What is the energy coin of a cell ?
(a) DNA (b) RNA
(c) ATP (d) Minerals
40. Pyruvate dehydrogenase complex is used in converting –
(a) Pyruvate to glucose (b) Glucose to pyruvate
(c) Pyruvic acid to lactic acid (d) Pyruvate to acetyl Co-A
41. Which of the following is a more accurate statement about respiration ?
(a) O2 must always be available for respiration.
(b) O2 combines with carbon to form CO2.
(c) O2 combines with hydrogen to form H2O.
(d) Air is inhaled and exhaled only from stomata.
42. The process of oxidative phosphorylation takes place in –
(a) Mitochondria (b) Chloroplasts
(c) Ribosomes (d) Cytoplasm
43. During which stage in the complete oxidation of glucose are the highest number of energy deriving molecules
(ATP) formed from ADP –
(a) Conversion of pyruric acid to acetyl CoA (b) Electron transport chain
(c) Glycolysis (d) Krebs cycle
44. Chemiosmotic theory of ATP synthesis is based on –
(a) Proton gradient (b) Accumulation of K ions
(c) Accumulation of Na ions (d) Membrane potential
45. In mitochondrial electron transport system, for every two pairs of electrons that pass from NADH molecules
through a sequential series of cytochrome enzymes to molecular oxygen generate
(a) 3 ATP (b) 4 ATP
(c) 6 ATP (d) 2 ATP
46. Which of the following statements regarding mitochondrial membrane is not correct ?
(a) The inner membrane is highly convoluted forming a series of infoldings
(b) The outer membrane resembles a sieve
(c) The outer membrane is permeable to all kinds of molecules
(d) The enzymes of the electron transfer chain are embedded in the outer membrane
47. Which of the following types of mammalian cell does not carry out oxidative phosphorylation?
(a) Cardiac muscle cells (b) Erythrocytes
(c) Neurons (d) Oxyntic cells
48. “Mitchell’s chemiosmotic theory” belongs to
(a) Kreb’s cycle (b) oxidative phosphorylation
(c) glycolysis (d) None of the above
49. What is the final pathway followed by all carbon atoms derived from carbohydrates, lipids and proteins when
they are oxidised during respiration?
(a) The Calvin cycle (b) The electron transport system
(c) The Krebs cycle (d) The ornithine cycle
50. The oxidation of a molecule of FADH2 yields less ATP than a molecue of NADH yields because FADH2
(a) carries fewer electrons.
(b) is formed in the cytosol and energy is lost when it shuttles its electrons across the mitochondrial membrane.
(c) passes its electrons to a transport molecule later in the chain and at a lower energy level.
(d) is the last molecule produced by the Krebs cycle, and little energy is left to be captured.
51. Which of the following substances is not an essential component of the tricarboxylic acid cycle?
(a) FAD (b) Succinyl CoA
(c) NADP (d) Citric acid
52. If CO2 is given off in respiration, why does the amount of CO2 in the atmosphere remains relatively constant ?
(a) CO2 forms carbonate rocks.
(b) CO2 is buffer.
(c) CO2 is converted in photosynthesis to carbohydrates.
(d) CO2 splits up during photosynthesis.
53. Decarboxylation is not involved in
(a) electron transport system (b) glycolysis
(c) Kreb’s cycle (d) alcoholic fermentation
54. The electron carrier molecules Q and cytochrome c
(a) are reduced as they pass electrons on to the next molecule.
(b) contain heme prosthetic groups.
(c) shuttle protons to ATP synthase.
(d) are mobile carriers that transfer electrons between the electron carrier complexes.
55. The number of carbon atom in citric acid is
(a) 8 (b) 6
(c) 10 (d) 2
56. Which one of the following is complex V of the ETS of inner mitochondrial membrane?
(a) NADH dehydrogenase (b) Cytochrome c oxidase
(c) Ubiquinone (d) ATP synthase
57. Which of the following processes make direct use of oxygen?
(a) Glycolysis (b) Fermentation
(c) Electron transport (d) Krebs citric acid cycle
58. Which intermediate compound is involved in the synthesis of amino acids?
(a) Malic acid (b) Citric acid
(c) a-ketoglutaric acid (d) Isocitric acid
59. FAD is electron acceptor during oxidation of which of the

60. Oxidation of succinate to fumarate in the Kereb's cycle is due to

(a) Loss of electron from it (b) Removal of hydrogen from it
(c) Addition of oxygen to it (d) None of the above
61. In electron transport system (ETS), which of the following cytochrome reacts with oxygen ?
(a) Cyt b (b) Cyt a3
(c) Cyt b6 (d) Cyt f
62. In an electron transport chain in terminal oxidation the cytochrome which donates electrons to O2 is
(a) Cytochrome b (b) Cytochrome c
(c) Cytochrome a3 (d) Cytochrome a
63. Which statement concerning ATP synthesis is true?
(a) ATP can be synthesized through substrate level phosphorylation, photophosphorylation and oxidative
phosphorylation.
(b) The proton-motive force is the establishment of proton gradients and electrochemical potentials across the inner
membrane.
(c) Proton-motive force is essential for back flow of H+ from outer chamber of matrix of mitochondria through
proton channel (F0) of F0 – F1 particle to produce ATP.
(d) All of the above
64. Which of the following processes make direct use of oxygen?
(a) Glycolysis (b) Fermentation
(c) Electron transport (d) Krebs citric acid cycle
65. Which one of the following is complex V of the ETS of inner mitochondrial membrane ?
(a) NADH dehydrogenase (b) Cytochrome c oxidase
(c) Ubiquinone (d) ATP synthetase
66. Which of the following is a 4-carbon compound?
(a) Oxaloacetic acid (b) Citric acid
(c) Phosphoglyceric acid (d) Phosphoenol pyruvate
67. Electron transport chain is inhibited by
(a) rotenone and amytal (b) antimycin-A
(c) cyanide (CN–), azide (N3 –) and carbon monoxide (CO) (d) All of the above
68. RQ (respiratory quotient) is defined as

69. Which of the following is necessary for respiration in plants ?

(a) Carbon dioxide (b) Oxygen
(c) Chlorophyll (d) Light
70. Which of the following pair is a combination of lowest and highest energy molecules ?
(a) Glucose and pyruvic acid (b) Acetyl CoA and palmitic acid
(c) Glucose and malic acid (d) Malic acid and acetyl CoA
71. R.Q. for glucose (Carbohydrates) is
(a) 1 (b) 0.5
(c) 2 (d) 0.05
72. If R. Q. is less than 1.0 in a respiratory metabolism, it would mean that
(a) Carbohydrates are used as respiratory substrate
(b) Organic acids are used as respiratory substrate
(c) The oxidation of the respiratory substrate consumed more oxygen than the amount of CO2 released
(d) The oxidation of the respiratory substrate consumed less oxygen than the amount of CO2 released
73. The R.Q. value of Oxalic acid is
(a) 1.0 (b) 0.7
(c) 1.5 (d) ¥
74. In animal cells, the first stage of glucose breakdown is
(a) Krebs cycle (b) glycolysis
(c) oxidative phosphorylation (d) electron transport chain
75. R.Q. in anaerobic respiration is
(a) 0 (b) ∞
(c) 1 (d) 1
76. Chemiosmotic theory of ATP synthesis in the chloroplasts and mitochondria is based on
(a) membrane potential (b) accumulation of Na ions
(c) accumulation of K ions (d) proton gradient
77. During the stage in the complete oxidation of glucose are the greatest number of ATP molecules formed from
ADP
(a) glycolysis
(b) krebs cycle
(c) conversion of pyruvic acid to acetyl Co-A
(d) electron transport chain
78. How many ATP molecules could maximally be generated from one molecule of glucose, if the complete oxidation
of one mole of glucose to CO2 and H2O yields 686 kcal and the useful chemical energy available in the high energy
phosphate bond of one mole of ATP is 12 kcal ?
(a) Thirty (b) Fifty-seven
(c) One (d) Two
79. All enzymes of TCA cycle are located in the mitochondrial matrix except one which is located in inner
mitochondrial membranes in eukaryotes and in cytosol in prokaryotes. This enzyme is
(a) isocitrate dehydrogenase (b) malate dehydrogenase
(c) succinate dehydrogenase (d) lactate dehydrogenase.
80. The energy-releasing process in which the substrate is oxidised without an external electron acceptor is called
(a) fermentation (b) photorespiration
(c) aerobic respiration (d) glycolysis
81. In TCA cycle the conversion of succinyl Co-A to succinic acid requires
(a) Acetyl Co-A + GTP + Ip (b) Acetyl Co-A + GDP + iP
(c) Co-A + GTP + iP (d) GDP + iP
82. The chemiosmotic coupling hypothesis of oxidative phosphorylation proposes that adenosine triphosphate (ATP)
is formed because:
(a) high energy bonds are formed in mitochondrial proteins
(b) ADP is pumped out of the matrix into the intermembrane space
(c) a proton gradient forms across the inner membrane
(d) there is a change in the permeability of the inner mitochondrial membrane toward adenosine diphosphate (ADP)
83. The energy - releasing metabolic process in which substrate is oxidised without an external electron acceptor is
called:
(a) glycolysis (b) fermentation
(c) aerobic respiration (d) photorespiration
84. Respiratory enzymes are located in
(a) Mitochondrial matrix (mitochondria) (b) Perimitochondrial space
(c) Cristae (d) Outer membrane
85. The correct sequence of electron acceptor in ATP synthesis is
(a) Cyt a a b c (b) Cyt b c a a3
(c) Cyt b c a3 a (d) Cyt c b a a3
86. FADH2 is produced during the following reaction
(a) Succinic acid to fumaric acid (b) Fumaric acid to malic acid
(c) Succinyl Co-A to succinic acid (d) Isocitric acid to oxaloacetic acid
87. Oxalosuccinic acid, an intermediary compound of Krebs cycle is a
(a) 6 carbon compound (b) 5 carbon compound
(c) 3 carbon compound (d) 4 carbon compound
88. Match Column - I with Column - II
Column - I Column - II
A. 4C Compound 1. Acetyl CoA
B. 2C Compound 2. Pyruvate
C. 5C Compound 3. Citric acid
D. 3C Compound 4. a-ketoglutaric acid
5. Malic acid

89. Match Column - I with Column - II

Column I Column II
A. EMP pathway 1. Mitochondrial matrix
B. TCA cycle 2. Cytoplasm
C. ETC 3. Inner mitochondrial membrane
ABC
(a) 1 2 3
(b) 2 1 3
(c) 2 3 1
(d) 3 2 1
90. Which of the following statement(s) is /are not true ?
1. One ATP molecule yields 32 kJ of energy.
2. When tripalmitin is used as a substrate, the RQ is 0.7.
3. Energy released by one molecule of glucose on complete oxidation corresponds to 1292 kJ.
(a) only (1) (b) (2) and (3)
(c) (1) and (3) (d) Only (2)
91. During Kreb’s cycle
1. acetyl Co-A combines with 4 carbon oxaloacetic acid to produce 6 carbon citric acid.
2. malic acid undergoes reduction to produce oxaloacetic acid.
3. in presence of Mn2+ and dehydrogenase enzyme, a-ketoglutaric acid is converted into succinyl CoA.
4. in presence of a-ketoglutaric acid dehydrogenase enzyme, a-ketoglutaric acid is converted into oxaloacetic acid.
(a) (1), (2) and (3) (b) (1) and (2)
(c) (2) and (4) (d) (1) and (3)
92. The ultimate electron acceptor of respiration in an aerobic organism is
(a) cytochrome (b) oxygen
(c) hydrogen (d) glucose
93. Phosphorylation of glucose during glycolysis is catalysed by
(a) phosphoglucomutase (b) phosphoglucoisomerase
(c) hexokinase (d) phosphorylase
94. Pyruvic acid, the key product of glycolysis can have many metabolic fates. Under aerobic condition it forms
(a) lactic acid (b) CO2 + H2O
(c) acetyl Co - A + CO2 (d) ethanol + CO2
95. Electron Transport System (ETS) is located in mitochondrial
(a) outer membrane (b) inter membrane space
(c) inner membrane (d) matrix
96. Which of the following exhibits the highest rate of respiration?
(a) Growing shoot apex (b) Germinating seed
(c) Root tip (d) Leaf bud
97. Choose the correct statement:
(a) Pyruvate is formed in the mitochondrial matrix.
(b) During the conversion of succinyl Co-A to succinic acid a molecule of ATP is synthesized.
(c) Oxygen is vital in respiration for removal of hydrogen.
(d) There is complete breakdown of glucose in fermentation.
98. Mitochondria are called powerhouses of the cell. Which of the following observations support this statement?
(a) Mitochondria synthesise ATP
(b) Mitochondria have a double membrane
(c) The enzymes of the Krebs' cycle and the cytochromes are found in mitochondria
(d) Mitochondria are found in almost all plants and animal cells.
99. The end product of oxidative phosphorylation is
(a) NADH (b) oxygen
(c) ADP (d) ATP + H2O
100. Match the following columns.
Column I Column II
A. Molecular oxygen 1. a-ketoglutaric acid
B. Electron acceptor 2. Hydrogen acceptor
C. Pyruvate dehydrogenase 3. Cytochrome-c
D. Decarboxylation 4. Acetyl Co-A
ANSWER KEY