New Cell Discovery_Analysis Paper_Reodique

NAGA COLLEGE FOUNDATION INC.
M.T. Villanueva Avenue, Naga City

GRADUATE STUDIES
1st Semester, School Year 2024 – 2025
Title: The Importance of New Cell Therapies in Treating Incurable Neurological

Diseases
Incurable neurological diseases are characterized by progressive damage to the brain

and nervous system, leading to significant morbidity, mortality, and healthcare costs.
Current treatments for these diseases often focus on managing symptoms, such as
motor function, cognitive decline, and pain. However, these treatments do not address
the underlying causes of the diseases, and their efficacy is often limited by their ability
to slow down disease progression rather than halt it. The traditional treatment options
for these diseases often focus on managing symptoms, but there is an increasing need
for more effective and targeted therapies. New cell therapies, including stem cell
therapy and gene editing, offer promising avenues for treating incurable neurological
diseases.
A study published in the journal Nature Medicine found that stem cells can promote
the survival and function of dopamine-producing neurons in PD patients. Another study
published in the Journal of Neurology, Neurosurgery, and Psychiatry found that stem
cells can reduce inflammation and improve motor function in patients with multiple
sclerosis (MS). Another study published in the journal Cell Stem Cell found that stem
cells can promote the growth and differentiation of new neurons in the hippocampus of
AD patients. For instance, a study published in the journal Nature Immunology found
that a new type of immune cell, known as immature neutrophils, has the ability to
promote repair in the optic nerve and spinal cord. Another study published in the
Journal of Clinical Neuroscience found that stem cells can promote motor function
recovery in patients with PD.
New cell therapies, which involve the use of stem cells or genetically modified cells to
replace or repair damaged cells, offer a promising approach to treating incurable
neurological diseases. Stem cells have the ability to differentiate into various cell types,
including neurons, oligodendrocytes, and astrocytes, which are crucial for maintaining
the structure and function of the nervous system. It suggest that new cell therapies hold
significant potential for treating incurable neurological diseases. The use of stem cells,
particularly mesenchymal and induced pluripotent stem cells, has shown promise in
improving motor function, reducing symptoms, and slowing down disease progression in
patients with Parkinson's disease, ALS, and multiple sclerosis. Additionally, neural stem
cell therapies have shown potential in promoting neuroregeneration and improving
functional outcomes in patients with stroke.
The development of new cell therapies offers a promising approach to treating

incurable neurological diseases. While further research is needed to fully understand
the efficacy and safety of these therapies, the findings of this analysis suggest that they
hold significant potential for improving patient outcomes and enhancing quality of life.
As researchers continue to explore the potential of new cell therapies, it is essential to
ensure that these treatments are developed with careful consideration of ethical and
regulatory concerns. New cell therapies offer promising avenues for treating incurable
neurological diseases. While these therapies face several challenges, they have the
potential to provide targeted and effective treatments that can improve quality of life for
patients with these diseases. Further research is needed to overcome the challenges
associated with new cell therapies and to develop safe and effective treatments for
incurable neurological diseases.
1
NAGA COLLEGE FOUNDATION INC.
M.T. Villanueva Avenue, Naga City
GRADUATE STUDIES
1st Semester, School Year 2024 – 2025
References:
Blesch et al. (2018). Stem cell-based therapy for spinal cord injury: a review of the
current state and future directions. Journal of Neurotrauma, 35(10), 1537-1545.
Choi et al. (2019). CRISPR-Cas9 gene editing for genetic disorders: a review of the
current state and future directions. Journal of Human Genetics, 64(10), 931-938.
Eggan et al. (2019). Induced pluripotent stem cells in regenerative medicine: a review of
the current state and future directions. Journal of Clinical Investigation, 129(5),
1524-1532.
Kim et al. (2020). Stem cell-based therapy for Parkinson's disease: A systematic review.
Journal of Parkinson's Disease, 10(1), 1-14.
Zhang et al. (2020). Mesenchymal stem cell therapy for multiple sclerosis: A systematic
review. Journal of Neuroimmunology, 335, 137-144.
Gao et al. (2020). Stem cell-based therapy for Alzheimer's disease: A systematic
review. Journal of Alzheimer's Disease, 72(2), 537-548.
Chen et al. (2020). Stem cell-based therapy for Parkinson's disease: A systematic
review. Journal of Clinical Neuroscience, 67, 131-138.
Prepared by: Ella Mae P. Reodique

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NAGA COLLEGE FOUNDATION INC.

M.T. Villanueva Avenue, Naga City

Title: The Importance of New Cell Therapies in Treating Incurable Neurological

Incurable neurological diseases are characterized by progressive damage to the brain

The development of new cell therapies offers a promising approach to treating

Prepared by: Ella Mae P. Reodique

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