A Capstone Project Report

A Capstone Project Report
“Liver Disease Prediction Model Using Machine
Learning”
From JAN/2024 to MAY/2024
CAP-769
Project Group Code: CARGC0066
SUBMITTED BY
Sushant Kumar Reg. No.: 12213958

Kajal Singh Reg. No.: 12210674
Tenzin Choten Reg. No.: 12204977
UNDER THE GUIDANCE OF

Ms. Ranjit Kaur 28632
Assistant Professor, School of Computer Application
Submitted in partial fulfilment of the requirements for the

award of degree of
Master Of Computer Application
Submitted to
LOVELY PROFESSIONAL UNIVERSITY.

PHAGWARA, PUNJAB
Declaration by student
To whom so ever it may concern

We, Sushant Kumar, Kajal Singh, and Tenzin Choten, hereby declare that the work done by us on “Liver
Disease Prediction Model Using Machine Learning” under the supervision of Ms. Ranjit Kaur, Asst.
Professor, Lovely professional University, Phagwara, Punjab, is a record of original work for the partial
fulfilment of the requirements for the award of the degree, Master of Computer Application.
Name of the Student (Registration Number):
Sushant Kumar (12213958)
Kajal Singh (12210674)
Tenzin Choten (12204977)
Signature of the student
Dated:
Declaration by the supervisor
To whom so ever it may concern

This is to certify Tenzin Choten, Kajal Singh, and Sushant Kumar from Lovely Professional University,
Phagwara, Punjab, has worked on “Liver Disease Prediction Model Using Machine Learning” under my
supervision from. It is further stated that the work carried out by the student is a record of original work
to the best of my knowledge for the partial fulfilment of the requirements for the award of the degree,
Master of Computer Application.
Name of Supervisor: Ms. Ranjit Kaur (28632),
Assistant Professor, School of Computer Application
Signature of Supervisor
Acknowledgement
The successful completion of this research paper would not have been possible without the invaluable
support and contributions of several individuals and institutions. We would like to express our sincere
gratitude to all of them.
First and foremost, We are deeply grateful to our esteemed supervisor, Ms. Ranjit Kaur, Assit. Professor
at Lovely Professional University. Her profound knowledge in the field of Machine Learning proved
instrumental in guiding us throughout this journey. Ms. Kaur's insightful suggestions, constructive
criticism, and unwavering encouragement helped us refine our research question, develop a robust
methodology, and navigate the complexities of the research process. Her dedication to our academic
growth and her belief in our abilities instilled in us the confidence to persevere through challenges
We would also like to extend our sincere appreciation to Lovely Professional University for providing the
perfect environment for academic exploration and research. The university's exceptional library resources,
including access to a vast collection of scholarly articles and databases, were invaluable for gathering
relevant information and strengthening the foundation of my research. Additionally, the supportive faculty
and staff were always available to answer my questions and offer guidance whenever needed.
ABSTRACT
Liver diseases represent a significant public health challenge worldwide, with diverse etiologies
and complex pathophysiological mechanisms. Early detection and accurate prediction of liver
disease progression are crucial for guiding clinical decision-making and improving patient
outcomes. In this research paper, we propose the development and evaluation of a comprehensive
liver disease prediction model leveraging machine learning algorithms and multiomic data
integration. The research aims to address existing gaps in predictive modeling for liver diseases,
including limited integration of multiomic data, sparse representation of rare disease subtypes, and
challenges in model interpretability and generalizability. The proposed methodology involves data
collection from publicly available sources, feature selection and engineering, model development
and evaluation using algorithms such as Logistic Regression, Random Forest, K-Nearest
Neighbors (KNN), Decision Tree, and Support Vector Machines (SVM), and validation on
independent cohorts of liver disease patients. Furthermore, the research seeks to enhance model
interpretability and explainability through feature importance analysis and visualization
techniques, and translate the findings into clinical practice through collaboration with healthcare
providers and stakeholders. By bridging the gap between data science and clinical medicine, this
research aims to advance the field of liver disease prediction and contribute to improved diagnosis,
prognosis, and personalized management of liver diseases.
CONTENTS
ABSTRACT i
LIST OF FIGURES 10
LIST OF TABLES 10
CHAPTER – 1: INTRODUCTION 12
1.1 Introduction
1.2 Importance of research
1.3 Scope of Research

CHAPTER – 2: REVIEW OF LITERATURE 19
2.1 Review of Literature
CHAPTER – 3: IMPLEMENTATION OF PROJECT 21
3.1 Machine Learning Workflow
3.2 Data Preparation Technique
3.3 ML Model Selection
3.4 System Requirement and input/output
3.4 Determining Key Features

CHAPTER – 4: RESULTS AND DISCUSSION 35
4.1 Performance Assessment Model
4.2 Final Remarks
FINAL CHAPTER: CONCLUSION AND FUTURE SCOPE 38
List of Tables
Serial Table no Caption Page no
no
1 Table 3.1 Information about Data 19-20
2 Table 4.1 Model Evaluation 33
List of Figures/ Charts
Serial Figure Caption Page No.

No. No.
1. Fig 3.1 Machine learning workflow 19
2. Fig 3.2 Sample Dataset 20
3. Fig 3.3 Attribute Visualization 23
4. Fig 3.4 No of Male and Female 23
5 Fig 3.5 Correlation matrix as a heatmap 32
6. Fig 4.1 Evaluation of liver disease prediction model 33
performance
7. Fig 4.2 Comparative analysis of liver disease 34

prediction model performance
8. Fig 4.3 Discrimination ability of liver disease 34
prediction model

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A Capstone Project Report

“Liver Disease Prediction Model Using Machine

From JAN/2024 to MAY/2024

Project Group Code: CARGC0066

Sushant Kumar Reg. No.: 12213958

UNDER THE GUIDANCE OF

Submitted in partial fulfilment of the requirements for the

Master Of Computer Application

LOVELY PROFESSIONAL UNIVERSITY.

To whom so ever it may concern

Name of the Student (Registration Number):

Sushant Kumar (12213958)

Kajal Singh (12210674)

Tenzin Choten (12204977)

Signature of the student

To whom so ever it may concern

Name of Supervisor: Ms. Ranjit Kaur (28632),

Assistant Professor, School of Computer Application

1.2 Importance of research

1.3 Scope of Research

CHAPTER – 3: IMPLEMENTATION OF PROJECT 21

3.1 Machine Learning Workflow

3.2 Data Preparation Technique

3.3 ML Model Selection

3.4 System Requirement and input/output

3.4 Determining Key Features

List of Figures/ Charts

Serial Figure Caption Page No.

7. Fig 4.2 Comparative analysis of liver disease 34

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