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    Organic Synthesis

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    zozoxo
    This document outlines various synthesis routes for transforming chemical compounds including: 1) Using hydrogen gas and a nickel catalyst to produce an alkane from an alkene via electrophilic addition. 2) Producing a primary amine from an alkene using bromine, UV light, ammonia, or sodium hydroxide via nucleophilic substitution or elimination. 3) Generating an alkene from a bromoalkane using sodium hydroxide or sodium bromide and hydrochloric acid via nucleophilic substitution.

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    Organic Synthesis

    Uploaded by

    zozoxo
    133 views1 page
    This document outlines various synthesis routes for transforming chemical compounds including: 1) Using hydrogen gas and a nickel catalyst to produce an alkane from an alkene via electrophilic addition. 2) Producing a primary amine from an alkene using bromine, UV light, ammonia, or sodium hydroxide via nucleophilic substitution or elimination. 3) Generating an alkene from a bromoalkane using sodium hydroxide or sodium bromide and hydrochloric acid via nucleophilic substitution.

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    This document outlines various synthesis routes for transforming chemical compounds including: 1) Using hydrogen gas and a nickel catalyst to produce an alkane from an alkene via electrophilic addition. 2) Producing a primary amine from an alkene using bromine, UV light, ammonia, or sodium hydroxide via nucleophilic substitution or elimination. 3) Generating an alkene from a bromoalkane using sodium hydroxide or sodium bromide and hydrochloric acid via nucleophilic substitution.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    133 views1 page

    Organic Synthesis

    Uploaded by

    zozoxo
    This document outlines various synthesis routes for transforming chemical compounds including: 1) Using hydrogen gas and a nickel catalyst to produce an alkane from an alkene via electrophilic addition. 2) Producing a primary amine from an alkene using bromine, UV light, ammonia, or sodium hydroxide via nucleophilic substitution or elimination. 3) Generating an alkene from a bromoalkane using sodium hydroxide or sodium bromide and hydrochloric acid via nucleophilic substitution.

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    Download as DOCX, PDF, TXT or read online from Scribd
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    Synthesis Routes

    H2 150c Nickel catalyst (Electrophilic addition)

    ALKANE
    Br2 UV light NH3/ Ethanol reflux (Nucleophilic substitution) NaOH/ Ethanol reflux (Elimination)

    PRIMARY AMINE

    BROMOALKANE
    NaOH Reflux (Nucleophilic substitution)
    NaBr/HCl H2SO4 Reflux (Nucleophilic substitution)

    ALKENE
    HBr 20c (Electrophilic addition) Br2 20c (Electrophilic addition)

    ALCOHOL
    K2Cr2O7 H2SO4 Heat then distil (Oxidation) LiAlH4 (dry ether) Heat (Reduction) HCN Ethanol Reflux (Nucleophilic substitution)

    DIBROMOALKANE

    LiAlH4 (dry ether) Heat (Reduction)

    ALDEHYDE/KETONE
    K2Cr2O7 H2SO4 Reflux (Oxidation)

    HYDROXYNITRILE

    Alcohol, H+ catalyst Reflux (Esterification)

    NITRILE
    HCl Reflux PCl5 20c

    CARBOXYLIC ACID
    H2O 20c H+ catalyst Reflux

    ESTER

    Alcohol 20c

    ACYL CHOLIDE
    NH3 20c Amine 20c

    PRIMARY AMIDE

    N-Substituted Amide

    Muhammad Ajij

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