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    Syndrome of Inappropriate Antidiuretic Hormone (Siadh) : Reported by Jo Jo Ale

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    8hg
    The document discusses Syndrome of Inappropriate Antidiuretic Hormone (SIADH), which is characterized by excessive release of antidiuretic hormone (ADH) that alters fluid and electrolyte balance. Complications include heart failure from fluid overload and cerebral edema from water intoxication. Causes include lung tumors, head injuries, and various medications. Symptoms include oliguria, edema, weight gain, nausea, and possible seizures or coma. Treatment focuses on correcting the underlying cause, using drugs to block ADH effects, and diuretics. Nursing care addresses excess fluid volume, risk for injury from seizures, and educating on water restriction and weight monitoring.

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    Syndrome of Inappropriate Antidiuretic Hormone (Siadh) : Reported by Jo Jo Ale

    Uploaded by

    8hg
    440 views9 pages
    The document discusses Syndrome of Inappropriate Antidiuretic Hormone (SIADH), which is characterized by excessive release of antidiuretic hormone (ADH) that alters fluid and electrolyte balance. Complications include heart failure from fluid overload and cerebral edema from water intoxication. Causes include lung tumors, head injuries, and various medications. Symptoms include oliguria, edema, weight gain, nausea, and possible seizures or coma. Treatment focuses on correcting the underlying cause, using drugs to block ADH effects, and diuretics. Nursing care addresses excess fluid volume, risk for injury from seizures, and educating on water restriction and weight monitoring.

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    (Siadh)

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    The document discusses Syndrome of Inappropriate Antidiuretic Hormone (SIADH), which is characterized by excessive release of antidiuretic hormone (ADH) that alters fluid and electrolyte balance. Complications include heart failure from fluid overload and cerebral edema from water intoxication. Causes include lung tumors, head injuries, and various medications. Symptoms include oliguria, edema, weight gain, nausea, and possible seizures or coma. Treatment focuses on correcting the underlying cause, using drugs to block ADH effects, and diuretics. Nursing care addresses excess fluid volume, risk for injury from seizures, and educating on water restriction and weight monitoring.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPT or read online from Scribd
    Download as ppt
    440 views9 pages

    Syndrome of Inappropriate Antidiuretic Hormone (Siadh) : Reported by Jo Jo Ale

    Uploaded by

    8hg
    The document discusses Syndrome of Inappropriate Antidiuretic Hormone (SIADH), which is characterized by excessive release of antidiuretic hormone (ADH) that alters fluid and electrolyte balance. Complications include heart failure from fluid overload and cerebral edema from water intoxication. Causes include lung tumors, head injuries, and various medications. Symptoms include oliguria, edema, weight gain, nausea, and possible seizures or coma. Treatment focuses on correcting the underlying cause, using drugs to block ADH effects, and diuretics. Nursing care addresses excess fluid volume, risk for injury from seizures, and educating on water restriction and weight monitoring.

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    SIADH is characterized by excessive release of antidiuretic hormone (ADH) that alters fluid and electrolyte balances and can cause complications like heart failure and cerebral edema. Key symptoms include oliguria, edema, and hyponatremia.

    Common causes and risk factors for SIADH include lung tumors, head injuries, pituitary surgery, various cancers, pulmonary diseases, and certain medications.

    Common symptoms of SIADH include oliguria, edema, weight gain, anorexia, nausea, vomiting, muscle weakness, twitching, lethargy, restlessness, possible seizures, confusion, and coma.

    Syndrome of Inappropriate

    Antidiuretic Hormone
    (SIADH)

    Reported By
    Jo jo Ale
    Syndr ome of Ina ppr opri ate
    An tidi ur etic H or mone (SI ADH )

     Definition:
     Is an abnormal condition characterized by
    excessive release of antidiuretic hormone
    (ADH) that alters the body’s fluid and
    electrolyte balances.
     Complications:
     Heart failure R/T fluid overload
     Cerebral edema secondary to water
    intoxication from fluid retention
     Causes / Etiology / Risk  Use of (iatrogenics): –
    Factors: Barbiturates,
     Lung tumor; head injury; anesthetics, thiazide
    pituitary surgery; diuretics –
    pancreatic & prostatic Chlorpropamide,
    cancer; Hodgkin’s vincristine,
    disease; pulmonary cyclophosphamide,
    disease; viral/bacterial clofibrate,
    COPD; bronchogenic metoclopramide,
    carcinoma, psychosis; morphine,
    myxedema; positive isoproteronal
    pressure ventilation
    Sym ptoma tolo g y
     Oliguria
     Edema (rare [water retention, water overload >
    4 L - increase CVP, increase PWP – much of
    free-water])
     Weight gain is within cellular boundaries
     Anorexia
     Nausea and vomiting
     Muscle weakness, Muscle twitching, Lethargy,
    Restlessness, Possible seizure, Confusion,
    Coma
    Pathophysiolo g y

    Etiology

    Increase secretion of ADH in the


    Blood stream

    Increases the permeability to water in the


    nephrons of kidneys

    Water absorption/retention
    Assessment / Diagnostics:

     Urine specific gravity > 1.030

     Dilutional of euvolemic hyponatremia (< 135


    mEq/L): mild (< 135); moderate (< 130);
    severe (< 125)
     Serum hypoosmolarity (< 280 mOsm/kg H2O)
     Normal renal function
     CT scan, MRI
    Treatment:
     correction of underlying cause of SIADH (e.g.,
    tumor surgery, radiation, chemotherapy)
     Drugs: – Cornivaptan (Vaprisol) is anti-ADH only
    in IV form so cannot be used in outpatient setting
     Diuretics such as furosemide (Lasix)
     Ototoxication
     Demeclocycline – to block renal response to ADH
     not used during the acute phase overdose
     may cause diabetes insipidus
    Nursing Diagnoses

    • Excess Fluid Volume R/T ↑ ADH


    • Risk for Injury R/T seizure
    • Altered Urinary Elimination r/t excess
    ADH level
    • Knowledge Deficit: Disease process
    r/t unfamiliarity of the illness
    Teaching:
    • 1. Need to maintain water restriction
    at home to prevent water
    intoxication.
    • 2. Get daily weight. Call Dr. if ↑ in
    weight is ≥ 1 kg/day.

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