Heavy Metals in Human Health

HEAVY METALS IN
HUMAN HEALTH
WHAT IS HEAVY METAL?
Heavy metals are individual metals and metal

compounds that can impact human health.
These are all naturally occurring substances

which are often present in the environment at
low levels. In larger amounts, they can be
dangerous.
Eight common heavy

metals
Arsenic
Barium
Cadmium
Chromium
Lead
Mercury
Selenium
Silver
Arsenic
Aside from occurring naturally in the

environment, arsenic can be released in
larger quantities through volcanic activity,
erosion of rocks, forest fires, and human
activity.
The wood preserving industry uses about

90% of the industrial arsenic in the U.S.
Arsenic is also found in paints, dyes,

metals, drugs, soaps and semi-conductors.
Animal feeding operations and certain

fertilizers and pesticides can release high
amounts of arsenic to the environment as
can industry practices such as copper or
lead smelting, mining, and coal burning.
Health effects
Arsenic is odorless and

tasteless. Inorganic arsenic is
a known carcinogen and can
cause cancer of the skin,
lungs, liver and bladder.
Lower level exposure can

cause nausea and vomiting,
decreased production of red
and white blood cells,
abnormal heart rhythm,
damage to blood vessels,
and a sensation of pins and
needles in hands and feet.
nausea and vomiting
Ingestion of very
high levels can
possibly result in
death.
Long-term low level

exposure can cause
a darkening of the
skin and the
appearance of small
corns or warts
on the palms, soles,
and torso.
Arsenic-induced
hyperkeratosis
of the hands
Regulatory limits
Environmental Protection
Agency (EPA) - 0.01 parts
per million (ppm) in
drinking water.
Occupational Safety and

Health Administration
(OSHA) - 10 micrograms
per cubic meter of
workplace air (10 g/ m3)
for 8 hour shifts and 40
hour work weeks.
Barium
Barium is a very abundant,
naturally occurring metal and is
used for a variety of industrial
purposes. Barium compounds, such
as barium-nickel alloys are used for
spark-plug electrodes and in
vacuum tubes as a drying and
oxygen-removing agent; barium
sulfide is used in fluorescent lamps;
barium sulfate is used in diagnostic
medicine; barium nitrate and
chlorate give fireworks a green
color. Barium compounds are also
used in drilling muds, paint, bricks,
ceramics, glass, and rubber.
Health effects
Barium is not known to cause

cancer.
Short term exposure can cause

vomiting, abdominal cramps,
diarrhea, difficulties in
breathing, increased or
decreased blood pressure,
numbness around the face, and
muscle weakness.
Large amounts of barium intake

can cause, high blood pressure,
changes in heart rhythm or
paralysis and possibly death.
Regulatory limits
EPA - 2.0 parts per million

(ppm) in drinking water.
OSHA - 0.5 milligrams of

soluble barium compounds per
cubic meter of workplace air for
8 hour shifts and 40 hour work
week.
Cadmium
Cadmium is a very toxic
metal. All soils and rocks,
including coal and mineral
fertilizers, contain some
cadmium. Cadmium has many
uses, including batteries,
pigments, metal coatings, and
plastics. It is used extensively
in electroplating.
Health effects
Cadmium and cadmium compounds

are known human carcinogens.
Smokers get exposed to significantly
higher cadmium levels than nonsmokers. Severe damage to the lungs
may occur through breathing high
levels of cadmium.
Ingesting very high levels severely

irritates the stomach, leading to
vomiting and diarrhea.
Long-term exposure to lower levels

leads to a buildup in the kidneys and
possible kidney disease, lung damage,
and fragile bones.
Regulatory limits
EPA 5 parts per billion (ppb)

or 0.005 parts per million (ppm)
of cadmium in drinking water
Food and Drug Administration

(FDA) concentration in bottled
drinking water should not exceed
0.005 ppm (5 ppb).
OSHA an average of 5
micrograms per cubic meter of
workplace air for an 8-hour
workday, 40-hour work week.
Chromium
Chromium is found in rocks, animals,
plants, and soil and can be a liquid,
solid, or gas. Chromium compounds
bind to soil and are not likely to
migrate to ground water but, they are
very persistent in sediments in water.
Chromium is used in metal alloys such
as stainless steel; protective coatings
on metal (electroplating); magnetic
tapes; and pigments for paints,
cement, paper, rubber, composition
floor covering and other materials. Its
soluble forms are used in wood
preservatives.
Health effects
Chromium (VI) compounds are toxins

and known human carcinogens,
whereas Chromium (III) is an essential
nutrient.
Breathing high levels can cause

irritation to the lining of the nose; nose
ulcers; runny nose; and breathing
problems, such as asthma, cough,
shortness of breath, or wheezing.
Skin contact can cause skin ulcers.

Allergic reactions consisting of severe
redness and swelling of the skin have
been noted.
Long term exposure can cause

damage to liver, kidney circulatory and
nerve tissues, as well as skin irritation.
Regulatory limits
EPA 0.1 ppm (parts per

million) in drinking water.
FDA should not exceed 1

milligram per liter (1 ppm) in
bottled water.
OSHA an average of
between 0.0005 and 1.0
milligram per cubic meter of
workplace air for an 8-hour
workday, 40-hour workweek,
depending on the compound.
Lead
As a result of human activities, such as fossil fuel

burning, mining, and manufacturing, lead and
lead compounds can be found in all parts of our
environment. This includes air, soil, and water.
Lead is used in many different ways. It is used

to produce batteries, ammunition, metal
products like solder and pipes, and X-ray
shielding devices. Lead is a highly toxic metal
and, as a result of related health concerns , its
use in several products like gasoline, paints, and
pipe solder, has been drastically reduced in
recent years. Today, the most common sources
of lead exposure in the United States are leadbased paint and possibly water pipes in older
homes, contaminated soil, household dust,
drinking water, lead crystal, lead in certain
cosmetics and toys, and lead-glazed pottery.
Health effects
EPA has determined that lead is a probable human

carcinogen. Lead can affect every organ and
system in the body. Long-term exposure of adults
can result in decreased performance in some tests
that measure functions of the nervous system;
weakness in fingers, wrists, or ankles; small
increases in blood pressure; and anemia.
Exposure to high lead levels can severely

damage the brain and kidneys and ultimately
cause death.
In pregnant women, high levels of exposure to

lead may cause miscarriage.
High level exposure in men can damage the

organs responsible for sperm production.
Regulatory limits
EPA 15 parts per billion

(ppb) in drinking water,0.15
micrograms per cubic meter
in air.
Mercury
Mercury combines with other elements

to form organic and inorganic mercury
compounds. Metallic mercury is used to
produce chlorine gas and caustic soda,
and is also used in thermometers, dental
fillings, switches, light bulbs, and
batteries.
Coal-burning power plants are the

largest human-caused source of mercury
emissions to the air in the United States.
Mercury in soil and water is converted by
microorganisms to methyl mercury, a bio
accumulating toxin.
Health effects
The EPA has determined that mercuric

chloride and methyl mercury are possible
human carcinogens.
The nervous system is very sensitive

to all forms of mercury.
Exposure to high levels can

permanently damage the brain, kidneys,
and developing fetuses. Effects on brain
functioning may result in irritability,
shyness, tremors, changes in vision or
hearing, and memory problems.
Short-term exposure to high levels of

metallic mercury vapors may cause lung
damage, nausea, vomiting, diarrhea,
increases in blood pressure or heart rate,
skin rashes, and eye irritation.
Mercury Toxicity
Regulatory limits
EPA 2 parts per billion parts

(ppb) in drinking water
FDA 1 part of methyl mercury

in a million parts of seafood.
OSHA 0.1 milligram of organic

mercury per cubic meter of
workplace air and 0.05 milligrams
per cubic meter of metallic
mercury vapor for 8-hour shifts
and 40-hour work week.

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HEAVY METALS IN

WHAT IS HEAVY METAL?

Heavy metals are individual metals and metal

These are all naturally occurring substances

Eight common heavy

Aside from occurring naturally in the

The wood preserving industry uses about

Arsenic is also found in paints, dyes,

Animal feeding operations and certain

Arsenic is odorless and

Lower level exposure can

Long-term low level

Occupational Safety and

Barium is not known to cause

Short term exposure can cause

Large amounts of barium intake

EPA - 2.0 parts per million

OSHA - 0.5 milligrams of

Cadmium and cadmium compounds

Ingesting very high levels severely

Long-term exposure to lower levels

EPA 5 parts per billion (ppb)

Food and Drug Administration

Chromium (VI) compounds are toxins

Breathing high levels can cause

Skin contact can cause skin ulcers.

Long term exposure can cause

EPA 0.1 ppm (parts per

FDA should not exceed 1

As a result of human activities, such as fossil fuel

Lead is used in many different ways. It is used

EPA has determined that lead is a probable human

Exposure to high lead levels can severely

In pregnant women, high levels of exposure to

High level exposure in men can damage the

EPA 15 parts per billion

Mercury combines with other elements

Coal-burning power plants are the

The EPA has determined that mercuric

The nervous system is very sensitive

Exposure to high levels can

Short-term exposure to high levels of

EPA 2 parts per billion parts

FDA 1 part of methyl mercury

OSHA 0.1 milligram of organic

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