Scribd Logo
Upload

Welcome to Scribd!

  • 2K views

    Histology, Lecture 5, Muscular Tissue (Slides)

    Uploaded by

    Ali Al-Qudsi
    Muscular tissue is composed of different cell types containing contractile fibers. There are three main types of muscle fibers - skeletal, cardiac, and smooth muscle. Skeletal muscle fibers are long, striated, and attached to bone. They contain structures like sarcomeres, T-tubules, and sarcoplasmic reticulum that allow for contraction. Cardiac muscle contains striations and structures like intercalated discs that allow synchronized contraction of the heart. Smooth muscle fibers are elongated and contain thin and thick filaments that slide past each other during contraction.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPTX, PDF, TXT or read online from Scribd

    Histology, Lecture 5, Muscular Tissue (Slides)

    Uploaded by

    Ali Al-Qudsi
    2K views17 pages
    Muscular tissue is composed of different cell types containing contractile fibers. There are three main types of muscle fibers - skeletal, cardiac, and smooth muscle. Skeletal muscle fibers are long, striated, and attached to bone. They contain structures like sarcomeres, T-tubules, and sarcoplasmic reticulum that allow for contraction. Cardiac muscle contains striations and structures like intercalated discs that allow synchronized contraction of the heart. Smooth muscle fibers are elongated and contain thin and thick filaments that slide past each other during contraction.

    Original Description:

    Histology, Lecture 5, Muscular Tissue (slides)

    Original Title

    Histology, Lecture 5, Muscular Tissue (slides)

    Copyright

    © Attribution Non-Commercial (BY-NC)

    Available Formats

    PPTX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Muscular tissue is composed of different cell types containing contractile fibers. There are three main types of muscle fibers - skeletal, cardiac, and smooth muscle. Skeletal muscle fibers are long, striated, and attached to bone. They contain structures like sarcomeres, T-tubules, and sarcoplasmic reticulum that allow for contraction. Cardiac muscle contains striations and structures like intercalated discs that allow synchronized contraction of the heart. Smooth muscle fibers are elongated and contain thin and thick filaments that slide past each other during contraction.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    2K views17 pages

    Histology, Lecture 5, Muscular Tissue (Slides)

    Uploaded by

    Ali Al-Qudsi
    Muscular tissue is composed of different cell types containing contractile fibers. There are three main types of muscle fibers - skeletal, cardiac, and smooth muscle. Skeletal muscle fibers are long, striated, and attached to bone. They contain structures like sarcomeres, T-tubules, and sarcoplasmic reticulum that allow for contraction. Cardiac muscle contains striations and structures like intercalated discs that allow synchronized contraction of the heart. Smooth muscle fibers are elongated and contain thin and thick filaments that slide past each other during contraction.

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    You are on page 1of 17

    Muscular Tissue

     Composed of different cells containing the contractile


    fibers
     Most of muscle cells are mesodermal in origin
     Three types of muscle fibers can be distinguished
    according to morphological and functional differences
    Skeletal Muscle
     Long thin multinucleated fibers
     10-100 µm in diameter and may reach 70 cm in length
     Peripheral flat nuclei
     Red in color due to myoglobin
     They are striated and attached to bone
     Sarcoplasmic reticulum,
    sarcolemma, sarcoplasm
     Hypertrophy and hyperplasia
    Organization of Skeletal Muscle
     Epimysium
     Perimysium
     Endomysium
     Connective tissue serves in:
    Transmits the force generated
    by individual fibers
    Blood and lymphatic vessels
    run in the connective tissue
    Organization of Skeletal Fiber
     In a sarcomere, identify the following
    A-band and myosin filamints
    I-band and actin filaments
    Z line and α actinin
    M line and creatine kinase
    H band
    Sarcoplasmic Reticulum
     Deplarization at myoneural junction leads to relaese of
    Ca+2
     Transverse (T) tubules: invagination of sarcolemma at
    the level of A-I bands
     Triade: T-tubule with dilatedcisternae
    of sarcoplasmic reticulum at the sides
    of T-Tubule
     Rigor Mortis
    Contraction of Skeletal Muscle
     A-band
     I-band
     Z lines
     H-band
     M-line
     Z-lines
    Innervation
    Myoneural Junction
    Structure
    Motor Unit
    Myasthenia gravis
    Types of Skeletal Fibers
    Type I: Red Oxidative or Slow
    Type IIa: Red, Fast, Intermediate Oxidative
    Type IIb: White, Fast, Glycolytic
    Cardiac Muscle Fiber
     Striated with central round nucleus They are 10x100µm
     Short branching fibers
     Endomysium surrounds
    each muscle fiber
     Intercalated discs
    Fascia adherens (Actin)
    Macula adheres
    Gap junction
    Characteristics of Cardiac Muscle
     More T-Tubules and form diads at Z-Line
     Sarcoplasmic reticulum is less
    profound and irregularly dispersed
     Contain numerous mitochondria
    (40% vz 2%)
     Fatty acids are stored in
    lipid droplets
     Lipofuscin pigments
     Membrane bound granules
    contain Atrial Natriuretic Factor
    act on kidney leads to
    Na and H2O loss
    Smooth Muscle Fiber
     Consists of elongated, non-striated muscle fibers
     It is surrounded by a basal lamina and reticular fibers
     It has a central ovoid nucleus and
    other cytoplasmic organelles
     Ill developed sarcoplasmic
    reticulum is not organized to
    tubules
     Contains thin filaments made
    of actin and tropomyosin and
    thick filaments made of myosin
     Intermediate filaments (Desmin and Vimentin)
     Dens bodies (Membranous and cytoplasmic)
    Types of Smooth Fibers
     Visceral: in the wall of viscera .They have gap
    junctions and poor nerve supply and contract in
    syncytial fashion (Bulk contraction)
     Multiunit: In the iris of the eye. They have rich
    innervation (Graded and precise action)
    Mechanism of contraction
     In skeletal and cardiac muscle fibers, calcium binds to
    troponin leading to change in the geometry of thin and
    thick filaments leading to contraction (sliding theory).
     In smooth muscle fiber, calcium binds to calmodulin
    which activate myosin light chian kinase leading to
    myosin phospholyration
     Factors leading to increase or decrease cAMP levels
    leads to contraction and relaxation, respectively
    Regeneration of Muscle Tissue
     Injured cardiac fibers after childhood are replaced
    by fibrous tissue
     Injured skeletal fibers have limited potential for
    regeneration. Satellite cells (Undifferentiated
    myoblasts) within the basal lamina of skeletal
    fibers become activated and proliferate and fuse
    together to give new muscle fibers
     Injured smooth fibers have active regenerative
    activity
    saffffsgd 

    You might also like