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    Introduction To Biochemistry

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    Hazel Lou
    This document provides information about a biochemistry course including: - It is worth 5 credit units consisting of 3 hours of lecture and 6 hours of laboratory per week. - Grades are based 50% on lecture and 50% on laboratory work, each assessed through quizzes and exams. - Topic outlines cover micromolecules, cellular components, proteins, enzymes and metabolism in the first half and lipids, nucleic acids and vitamins in the second half. - Biochemistry studies the chemistry of living organisms and physiological and pathological chemical processes underlying biological functions.

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    © All Rights Reserved
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    Introduction To Biochemistry

    Uploaded by

    Hazel Lou
    839 views32 pages
    This document provides information about a biochemistry course including: - It is worth 5 credit units consisting of 3 hours of lecture and 6 hours of laboratory per week. - Grades are based 50% on lecture and 50% on laboratory work, each assessed through quizzes and exams. - Topic outlines cover micromolecules, cellular components, proteins, enzymes and metabolism in the first half and lipids, nucleic acids and vitamins in the second half. - Biochemistry studies the chemistry of living organisms and physiological and pathological chemical processes underlying biological functions.

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    Biochem

    Original Title

    01. Introduction to Biochemistry

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    This document provides information about a biochemistry course including: - It is worth 5 credit units consisting of 3 hours of lecture and 6 hours of laboratory per week. - Grades are based 50% on lecture and 50% on laboratory work, each assessed through quizzes and exams. - Topic outlines cover micromolecules, cellular components, proteins, enzymes and metabolism in the first half and lipids, nucleic acids and vitamins in the second half. - Biochemistry studies the chemistry of living organisms and physiological and pathological chemical processes underlying biological functions.

    Copyright:

    © All Rights Reserved
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    Download as pptx, pdf, or txt
    839 views32 pages

    Introduction To Biochemistry

    Uploaded by

    Hazel Lou
    This document provides information about a biochemistry course including: - It is worth 5 credit units consisting of 3 hours of lecture and 6 hours of laboratory per week. - Grades are based 50% on lecture and 50% on laboratory work, each assessed through quizzes and exams. - Topic outlines cover micromolecules, cellular components, proteins, enzymes and metabolism in the first half and lipids, nucleic acids and vitamins in the second half. - Biochemistry studies the chemistry of living organisms and physiological and pathological chemical processes underlying biological functions.

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    You are on page 1of 32

    BIOCHEMISTRY

    Geromil J. Lara, RMT,MSMT


    BIOCHEMISTRY
    • CREDIT: 5 units (3-2)
    – 3 Hours Lecture
    – 6 Hours Laboratory

    • Grading System
    – Lecture = 50%
    – Laboratory = 50%
    BIOCHEMISTRY
    • Grading System
    – Lecture = 50%
    • Quizzes = 50%
    • Long Exam = 50%

    – Laboratory = 50%
    • Quizzes = 50%
    • Written Exam = 50%
    BIOCHEMISTRY
    • Topic Outline
    – Midterm
    • Review of Micromolecules
    • The Living Cell
    • Amino Acids and Proteins
    • Enzymes
    • Carbohydrates
    BIOCHEMISTRY
    • Topic Outline
    – Finals
    • Lipids
    • Nucleic Acids
    • Metabolisms
    • Vitamins and Minerals
    BIOCHEMISTRY
    • Deals with the study of the chemistry of living
    organisms
    • Application of the principles and methods of
    chemistry to the field of biology and
    physiology
    • Concerned with the physico-chemical
    processes underlying
    – Digestion, absorption, circulation, respiration,
    metabolism, growth, and reproduction
    BIOCHEMISTRY

    Why study Biochemistry?


    BIOCHEMISTRY
    • To describe and explain in molecular terms all
    chemical processes of living cells.

    • Knowledge in biochemistry is essential to all


    life sciences.

    • A reciprocal relationship between


    biochemistry and medicine has stimulated
    mutual advances.
    BIOCHEMISTRY
    • Normal biochemical processes are the basis of
    health.

    • Biochemical research has impact on nutrition


    and preventive medicine.

    • Most and perhaps all disease has biochemical


    basis.
    BIOCHEMISTRY
    • is both a life science and a chemical
    science

    • it explores the chemistry of living


    organisms and the molecular basis for
    the changes occurring in living cells
    BIOCHEMISTRY
    • has become the foundation for
    understanding all biological
    processes

    • it has provided explanations for the


    causes of many diseases in humans,
    animals and plants
    BIOCHEMISTRY

    Biochemistry
    and
    Medicine
    BIOCHEMISTRY
    • Clinical Biochemistry

    – Physiological Chemistry
    • Normal processes

    – Pathological Chemistry
    • Abnormal processes
    Major Causes of Disease

    • Physical Agents: mechanical trauma,


    temperature extremes, radiation, electric
    shock
    • Chemical Agents: toxic compounds, drugs
    • Biologic Agents: viruses, bacteria, fungi,
    parasites, biochemistry professors
    • Genetic Disease
    • Oxygen Lack: loss of blood, decreased
    oxygen-carrying capacity of blood,
    mitochondrial poisoning
    Disease Causes (cont.)

    • Immunologic Reactions:
    anaphylaxis, autoimmune disorders
    • Nutritional Imbalances:
    deficiencies, excesses
    • Endocrine Imbalances: hormonal
    deficiencies/excesses
    REVIEW OF BIOMOLECULES
    ORGANIC COMPOUNDS
    • 2 General Classifications
    1. HYDROCARBONS
    • Contain only carbon and hydrogen

    • ALIPATHIC HYDROCARBONS
    – No benzene rings or a derivative of the
    benzene ring
    – ALKANES, ALKENES, AND ALKYNES
    • AROMATIC HYDROCARBONS
    – Contain a benzene ring or a derivative of
    the benzene ring
    HYDROCARBONS

    ALIPATHIC AROMATIC

    Saturated – Unsaturated –
    contain single contain 2 or
    C-H bond more C-H bond

    Alkanes – Alkenes – Alkynes –


    contain only contain at least contain at least
    single bond one double one triple bond
    (ethane) bond (ethene) (ethyne)
    ORGANIC COMPOUNDS
    • General Classifications
    2. Substituted Hydrocarbons
    • Which one or more hydrogen atoms is
    replaced by another atom or group of
    atoms
    • Functional group
    – Is an atom or group of atoms arranged
    in a particular way that is primarily
    responsible for the chemical and
    physical properties of the molecule in
    which it is found
    HYDROPHOBICITY vs. HYDROPHILICITY

    • HYDROPHOBIC • HYDROPHILIC
    • Refers to the • Refers to a physical
    physical property of property of a
    a molecule that is molecule that can
    repelled from a mass transiently bond with
    of water water (H2O) through
    hydrogen bonding

    • Alkanes, oils, and


    fats
    CHEMICAL BONDS
    • 2 Principal
    Classes
    1. Ionic Bonding
    • Involves a
    transfer of one
    or more
    electrons from
    one atom to
    another,
    leading to the
    formation of an
    ionic bond
    CHEMICAL BONDS
    • 2 Principal
    Classes
    2. Covalent
    Bonding

    – Involves a
    sharing pairs
    of electrons
    between
    atoms
    CHEMICAL BONDS

    • H yd r o g e n
    Bonding
    – H yd r o g e n a t o m
    is bonded to a
    small, highly
    electronegative
    atom
    NEXT MEETING: THE CELL

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