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    International System of Units: Pharmaceutical Calculation

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    Daniel Pendon
    The document discusses the International System of Units (SI) used for measurements in pharmacy. It provides guidelines and examples for correctly using SI units and converting between units. The objectives are to demonstrate understanding of SI units, convert between units, state equivalent measures, and apply SI units in calculations. Examples are provided for reducing units, addition, subtraction, multiplication, and division using SI units. Practice problems at the end test the reader's ability to perform calculations involving common unit conversions in pharmacy.

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    International System of Units: Pharmaceutical Calculation

    Uploaded by

    Daniel Pendon
    356 views22 pages
    The document discusses the International System of Units (SI) used for measurements in pharmacy. It provides guidelines and examples for correctly using SI units and converting between units. The objectives are to demonstrate understanding of SI units, convert between units, state equivalent measures, and apply SI units in calculations. Examples are provided for reducing units, addition, subtraction, multiplication, and division using SI units. Practice problems at the end test the reader's ability to perform calculations involving common unit conversions in pharmacy.

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    International System of Units

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    The document discusses the International System of Units (SI) used for measurements in pharmacy. It provides guidelines and examples for correctly using SI units and converting between units. The objectives are to demonstrate understanding of SI units, convert between units, state equivalent measures, and apply SI units in calculations. Examples are provided for reducing units, addition, subtraction, multiplication, and division using SI units. Practice problems at the end test the reader's ability to perform calculations involving common unit conversions in pharmacy.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Download as pptx, pdf, or txt
    356 views22 pages

    International System of Units: Pharmaceutical Calculation

    Uploaded by

    Daniel Pendon
    The document discusses the International System of Units (SI) used for measurements in pharmacy. It provides guidelines and examples for correctly using SI units and converting between units. The objectives are to demonstrate understanding of SI units, convert between units, state equivalent measures, and apply SI units in calculations. Examples are provided for reducing units, addition, subtraction, multiplication, and division using SI units. Practice problems at the end test the reader's ability to perform calculations involving common unit conversions in pharmacy.

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    International System of Units

    Pharmaceutical Calculation
    Objectives

    • Demonstrate an understanding of the International System of Units

    • Convert measures within the International System of Units

    • State equivalent measures and complete conversions between the International


    System of Units and other systems of measure used in pharmacy

    • Apply the International System of Units correctly in calculations


    Introduction International System of Units (SI)

    • Formerly called metric system

    • Base units:
    • Length = Meter
    • Weight = Kilogram
    • Volume =Liter
    Guidelines for Correct Use

    • Two symbols for microgram • Leading zero should be used before all
    − mcg decimals
    − μg − 0.5 mg
    − NOT .5 mg
    • Decimals are used, not fractions • Trailing zeros should not be placed after
    whole numbers
    - 5.25 mg − 5 mg
    - NOT 5 ¼ mg − NOT 5.0 mg
    Common Conversions

    • Length
    − 1 m = 100 cm • Weight
    − 100 cm = 1000 mm − 1 g = 1000 mg
    − 1 g = kg
    • Volume − 1 mg = 1000 mcg
    − 1 L = 1000 mL
    Useful Equivalents

    Ansel, H. C. (2009) Phamaceutical Calculations (13th Ed.). Philadelphia:Lippincott


    Williams & Wilkins, and Wolters Kluwer Publishers
    SI Prefixes

    Ansel, H. C. (2009) Phamaceutical Calculations (13th Ed.). Philadelphia:Lippincott


    Williams & Wilkins, and Wolters Kluwer Publishers
    Practice Problem 1: Reducing SI Units

    • By decimal shift
    − Reduce 9876 milligrams to grams
    • To convert from smaller to larger number shift the decimal to the LEFT
    • 9876 mg =9.876 g

    − Reduce liters to microliters


    • To convert from larger to smaller number shift the decimal to the RIGHT
    • 2.525 L = 2525 mL = 2,525,000 mcL
    Practice Problem 2: Reducing SI Units

    •  Reduce 85 microgram to centigram


    • By ratio and proportion: (KNOW 1 cg = 10000mcg)

    .
    x = 0.00085 cg
    Practice Problem 2: Reducing SI Units

    •  Reduce 85 micrograms to centigrams


    − By dimensional analysis: (KNOW 1 cg = mcg)

    85 mcg x = 0.00085 cg
    Practice Problem 3: Addition

    • Reduce to common denomination then add or subtract


    • Add 1 kg, 250 mg, and 7.5 g
    − 1 kg = 1000 g
    − 250 mg = 0.25 g

    1000 g
    0.25 g
    + 7.5 g
    1007.75 g
    Practice Problem 4: Subtraction

    • Reduce to common denomination then add or subtract


    • Subtract 2.5 mg from 4.85 g
    − 2.5 mg = 0.0025 g

    4.85 g
    - 0.0025 g
    4.8475 g
    Practice Problem 4: Multiplication

    •  Multiply 820 mL by 12.5 and express the result in liters

    820 mL x 12.5 = 10250 mL

    10250 mL x = 10.25 L
    Practice Problem 4: Division

    •  Divide 0.465 g by 15 and express the result in milligrams

    = 0.031 g

    0.031 g x = 31 mg
    QUESTIONS?
    Problem 1

    A liquid contains 0.25 mg of a substance per milliliter. How many grams of the substance
    will 3.5 L contain?

    Ansel, H. C. (2009) Phamaceutical Calculations (13th Ed.). Philadelphia:Lippincott


    Williams & Wilkins, and Wolters Kluwer Publishers
    Problem 2

    Aspirin tablets generally contain 325 mg of aspirin. How many such tablets may be
    prepared from the 5 kg of aspirin?

    Ansel, H. C. (2009) Phamaceutical Calculations (13th Ed.). Philadelphia:Lippincott


    Williams & Wilkins, and Wolters Kluwer Publishers
    Problem 3

    Norgestrel and ethinyl estradiol tablets are available containing 0.5 mg of norgestrel and
    50 mcg of ethinyl estradiol. How many grams of each ingredient would be used in
    making 10,000 tablets?

    Ansel, H. C. (2009) Phamaceutical Calculations (13th Ed.). Philadelphia:Lippincott


    Williams & Wilkins, and Wolters Kluwer Publishers
    Problem 4

    A patient is instructed to take three 50 mcg tablets of pergolide mesylate (PERMAX)


    daily. How many mg of the drug would the patient receive weekly?

    Ansel, H. C. (2009) Phamaceutical Calculations (13th Ed.). Philadelphia:Lippincott


    Williams & Wilkins, and Wolters Kluwer Publishers
    Problem 5

    A prefilled syringe contains 20 mg of a drug in 2 mL of solution. How many micrograms


    of drug would be administered by an injection of 0.5 mL of the solution?

    Ansel, H. C. (2009) Phamaceutical Calculations (13th Ed.). Philadelphia:Lippincott


    Williams & Wilkins, and Wolters Kluwer Publishers
    Problem 6

    If an albuterol inhaler contains 18 mg of albuterol, how many inhalation doses can be


    delivered if each inhalation dose contains 90 mcg?

    Ansel, H. C. (2009) Phamaceutical Calculations (13th Ed.). Philadelphia:Lippincott


    Williams & Wilkins, and Wolters Kluwer Publishers
    Problem 7

    The product of biotechnology, filgrastim (NEUPOGEN), is available in vials containing 0.3


    mg of drug in each milliliter. Which choice is equivalent in concentration?
    (a) 0.03 mg/0.1 dL
    (b) 300 mcg/0.01 dL
    (c) 3 mcg/0.01 cL
    (d) 300 mcg/10 cL
    (e) 300 mcg/0.01 dL

    Ansel, H. C. (2009) Phamaceutical Calculations (13th Ed.). Philadelphia:Lippincott


    Williams & Wilkins, and Wolters Kluwer Publishers

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