This document discusses the formation of tissues and organ systems during the first and second trimesters of pregnancy. It explains that the three germ layers (ectoderm, endoderm, and mesoderm) differentiate into the four basic tissues (epithelial, connective, muscular, and nervous) through a process called organogenesis. During the second trimester, rapid growth and differentiation occurs as organ systems fully form. Certain birth defects can result if the embryo is exposed to teratogens like alcohol during critical periods of development in the early weeks.
This document discusses the formation of tissues and organ systems during the first and second trimesters of pregnancy. It explains that the three germ layers (ectoderm, endoderm, and mesoderm) differentiate into the four basic tissues (epithelial, connective, muscular, and nervous) through a process called organogenesis. During the second trimester, rapid growth and differentiation occurs as organ systems fully form. Certain birth defects can result if the embryo is exposed to teratogens like alcohol during critical periods of development in the early weeks.
This document discusses the formation of tissues and organ systems during the first and second trimesters of pregnancy. It explains that the three germ layers (ectoderm, endoderm, and mesoderm) differentiate into the four basic tissues (epithelial, connective, muscular, and nervous) through a process called organogenesis. During the second trimester, rapid growth and differentiation occurs as organ systems fully form. Certain birth defects can result if the embryo is exposed to teratogens like alcohol during critical periods of development in the early weeks.
This document discusses the formation of tissues and organ systems during the first and second trimesters of pregnancy. It explains that the three germ layers (ectoderm, endoderm, and mesoderm) differentiate into the four basic tissues (epithelial, connective, muscular, and nervous) through a process called organogenesis. During the second trimester, rapid growth and differentiation occurs as organ systems fully form. Certain birth defects can result if the embryo is exposed to teratogens like alcohol during critical periods of development in the early weeks.
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First and Second Trimester
Dep. Anatomi FK USU 2020
Formation of Tissues of the Body • Functional differentiation of cells of germ layers and organogenesis takes place during the embryonic period. • Germ layers are: The ectoderm differentiates into surface ectoderm, neuroectoderm and neural crest cells. The endoderm contributes for the formation of digestive and respiratory systems. The intraembryonic mesoderm is divided into three parts, i.e. paraxial, intermediate and lateral plate mesoderm. The musculoskeletal, blood vascular and parts of urinary and genital systems develop from them. The four basic tissues of the human body are derivatives of germ layers. 1) Epithelial tissue: Epithelium consists of cells arranged in the form of continuous sheets. Epithelia line the external and internal surfaces of the body and of body cavities. 2) Connective tissue: Connective tissue proper includes loose connective tissue, dense connective tissue and adipose tissue. Blood, cartilage and bone are special connective tissues. 3) Muscular tissue: three types: (1) skeletal, (2) cardiac and (3) smooth. 4) Nervous tissue: consists of neurons (nerve cells), nerve cell processes (axons and dendrites) and cells of neuroglia • At the beginning of the fetal period (9th week to 3rd month), the embryo has developed into a recognizable human being and the primordia of all organ system have formed. • Fetal period → t h e rapid growth in body size and toward differentiation of tissues, organs and organ systems. the growth of the head is slow as compared to that of the rest of body. At the beginning of 3rd month, the head is half the CRL (Crown-rump length), while at birth it is about one-fourth of CRL. Fetal weight gain is very rapid in the last month of pregnancy. Clinical correlation The embryo is highly sensitive to teratogens during 15th to 18th day (3rd week/ gastrulation period) of development as the primitive streak and its derivatives will be affected. Holoprosencephaly; the forebrain is small and the two lateral ventricles fuse into a single cavity,the eyes are closely placed (hypertelorism). High doses of alcohol in the mother can cause this condition. Caudal dysgenesis (Sirenomelia); Deficiency of mesoderm in the caudal part of the embryo that normally contributes for the formation of lower limbs, urogenital system and lumbosacral vertebrae. → T h e child is born with fused lower limbs and presents renal, genital and vertebral anomalies including imperforate anus. → T h i s condition is more common in mother with diabetes Sacrococcygeal teratoma; Persistence of pluripotent cells of primitive streak at the caudal end of embryonic disc after 4th week of gestation gives rise to a large tumor called sacrococcygeal teratoma. → c a u s e obstruction during labor and is usually malignant. It has to be removed within 6 months after birth. EMBRIOLOGY TIME LINE Second Trimester