Pinned
The last several months have been financially tight and I'm still trying to claw my way out of the hole I'm in. By time all my bills finish posting on the 20th, I'll be -$40 in the hole, and that doesn't even count the fact that I still need to pick up $20 in prescriptions and buy groceries and toilet paper. $120 would cover everything.
not furniture but love this 1930s radiator with bread warming addition
I don’t care if you make fun of Catholicism as long as it’s accurate! The best humour has its roots in the truth.
“You can be mean to me but there are RULES about it” is the most Catholic thing I’ve ever seen.
I walked into that one
awow. awow. awow. Awow. awowAwowawowAwow awow awow awow. bup bup bupbup bup bup bup bup bup. if you even care
btw. if you even care btw. btw
Love them sm
okay but if you ever see a male creative who had a string of great work and then everything else he did was dogshit, go to the "personal life" part of his wikipedia and look at his relationships. you'll either find a major tragedy he didn't recover from (completely understandable) or, more likely, there was a woman in his life doing uncredited shit editing his stuff or contributing generally and she's not there anymore.
I told a friend about this phenomenon in literature and he called me weeks later like, I remembered what you said about women doing uncredited work when tim burton came up. he made a string of bangers then everything else just was nowhere near as good. the timeline matches perfectly to when he was with this german visual artist (lena gieseke). he's done some good work in collaboration, but if things were dug into I suspect we would find she did a lot more than people realise.
so yeah whenever you look around like wow women didn't work in history, or, women aren't auteurs, or, there just aren't as many great female writers - societal reasons for that aside, half the time they absolutely did.
Hell yeah
Yellowstone Wildflowers, Regeneration after a forest fire.
worlds slowest fanfic author tries really really hard
everyone in the notes we are all holding hands. everyone who hasnt worked on a wip in weeks or months or years, its okay. we are going slow but we are going
ao3 tumblr added these tags and they are perfect
Among the latest discoveries in Pompeii:
A house with a private bathhouse , complete with hot, warm and cold rooms, and a plunge pool.
In a room were found the skeletons of a woman of about 40 years and a man of about 20 as well a pair of gold and natural pearl earrings.
The wonderful Pompeian red on the walls
Frescoes, various valuable objects, and gold coins.
Pompeii Parco Archeologico
…Can I still say “good for her”?
Bonus: If I buy a book I get to keep it! The publisher can't turn up at my house at random and confiscate all the books I bought.
"Two researchers in the US and Australia have discovered important mechanisms that prevent B cells from attacking the body’s own tissues in autoimmune diseases like arthritis, lupus, and multiple sclerosis—and in the process have won a prestigious prize.
Normally, the body’s immune system protects us from viruses, bacteria, and foreign substances. However, in autoimmune diseases, the immune system starts attacking tissues in the body instead.
Researchers had long tried to discover the cause of autoimmune diseases. But, Christopher Goodnow and David Nemazee, independently of each other, adopted a new approach.
They asked why we do not all develop these diseases. Their focus was on B cells which, together with white blood cells and T cells, are the building blocks of our complex immune system.
“They have given us a new and detailed understanding of the mechanisms that normally prevent faulty B cells from attacking tissues in the body, explaining why most of us are not affected by autoimmune diseases,” says Olle Kämpe, member of the Royal Swedish Academy of Sciences and chair of the Crafoord Prize committee that awarded the pair 6 million Swedish kronor ($600,000).
In recent years, physicians have started to experiment by using existing drugs to neutralize B cells for patients with severe autoimmune diseases, including lupus, rheumatoid arthritis, and multiple sclerosis, which has proven to be very effective at improving their quality of life.
Thanks to this year’s Crafoord Prize Laureates, we have gained fundamental new knowledge about what is happening in the immune system during autoimmune disease attacks.
“This also paves the way for development of new forms of therapies that eventually can cure these diseases—or might prevent them in the future,” said one professor of clinical immunology at the Royal Swedish Academy of Sciences...
More details from the video, since the article glosses over the particulars:
"The laureates discovered what is now called B cell tolerance.
When B cells develop in the bone marrow, not all of them are perfect. To remove the faulty ones, a mechanism starts, in which defective cells are programmed to destroy themself through apoptosis.
The laureates discovered two new mechanisms that are used if some of the bad cells are left. Re-editing, where the immune system alters the combination of receptors, and anergy, that silences B cells with self-reactive receptors.
The laureates were able to demonstrate that these mechanisms sometimes fail. This means that faulty B cells can cause an attack on the body's own tissues – leading to autoimmune diseases.
Thanks to the laureate’s discoveries, doctors like Anders Bengtsson soon felt able to start treating patients with lupus, arthritis, multiple sclerosis, and many other autoimmune diseases, with medicines that eradicated B cells.
Anders Bengtsson: "I'm very happy that B cells has gotten so much attention because of the laureates. I have seen my patients getting so much better and getting a better life."
Autoimmune patient: "Today, I feel very good. I really have hope in the research that it will revolutionise things and perhaps even cure it all. That’s what I want, hope for, and believe in.""
-Article via Good News Network, April 6, 2025. Video via The Royal Swedish Academy of Sciences, January 29, 2025.
No way out
idiot jail for ignorant beasts
Sisyphus
one must imagine sisyphus ouppy
I feel like pirating media that isn’t sold or offered anywhere legally anymore shouldn’t be called piracy. Girl thats archaeology
