Recent advances in obesity: genetics and beyond (Q35855592)

10 August 2017

Recent advances in obesity: genetics and beyond (English)

1 reference

10 August 2017

0 references

Wai W Cheung

1

1 reference

10 August 2017

Peizhong Mao

series ordinal

2

1 reference

10 August 2017

language of work or name

1 reference

5 March 2012

1 reference

10 August 2017

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10 August 2017

2012

1 reference

10 August 2017

536905

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Creative Commons Attribution 3.0 Unported

10 August 2017

start time

5 March 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

cites work

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Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: implications for early intervention and therapeutics

11 July 2018

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Potential Antidepressant Role of Neurotransmitter CART: Implications for Mental Disorders

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Genomics, type 2 diabetes, and obesity

11 July 2018

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11 July 2018

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Perinatal exposure to high-fat diet programs energy balance, metabolism and behavior in adulthood

11 July 2018

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Overexpression of Fto leads to increased food intake and results in obesity

11 July 2018

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Chronobiological aspects of nutrition, metabolic syndrome and obesity.

11 July 2018

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Chromosome 16p11.2 deletions: another piece in the genetic puzzle of childhood obesity

11 July 2018

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A new missense mutation in the leptin gene causes mild obesity and hypogonadism without affecting T cell responsiveness

11 July 2018

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The genetics of obesity: FTO leads the way.

11 July 2018

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Chronic consumption of a high-fat diet during pregnancy causes perturbations in the serotonergic system and increased anxiety-like behavior in nonhuman primate offspring

11 July 2018

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Progress in the genetics of common obesity and type 2 diabetes

11 July 2018

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A new highly penetrant form of obesity due to deletions on chromosome 16p11.2.

11 July 2018

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DNA microarrays to define and search for genes associated with obesity

11 July 2018

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Recent progress in the genetics of common obesity

11 July 2018

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Large, rare chromosomal deletions associated with severe early-onset obesity

11 July 2018

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An integrative view of obesity

11 July 2018

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Metabolism and circadian rhythms--implications for obesity

11 July 2018

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Circadian biology and sleep: missing links in obesity and metabolism?

11 July 2018

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Role of exercise-induced brain-derived neurotrophic factor production in the regulation of energy homeostasis in mammals

11 July 2018

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The genetic contribution to non-syndromic human obesity

11 July 2018

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Circadian rhythm of clock genes in human adipose explants

11 July 2018

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Admixture mapping of 15,280 African Americans identifies obesity susceptibility loci on chromosomes 5 and X.

11 July 2018

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Six new loci associated with body mass index highlight a neuronal influence on body weight regulation

11 July 2018

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Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity

11 July 2018

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Adipose tissue: the new endocrine organ? A review article

11 July 2018

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Recent advances and future research directions in neurogastroenterology and endocrinology recommendations of the National Commission on Digestive Diseases

11 July 2018

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Overweight is associated with decreased cognitive functioning among school-age children and adolescents

11 July 2018

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Common variants near MC4R are associated with fat mass, weight and risk of obesity

11 July 2018

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Regulation of Fto/Ftm gene expression in mice and humans

11 July 2018

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The obesity gene, FTO, is of ancient origin, up-regulated during food deprivation and expressed in neurons of feeding-related nuclei of the brain

11 July 2018

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Ghrelin, obesity and diabetes

11 July 2018

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Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits

11 July 2018

1 reference

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Copy number variants and genetic traits: closer to the resolution of phenotypic to genotypic variability

11 July 2018

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Mitochondrial mechanism of neuroprotection by CART

11 July 2018

1 reference

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Variation in FTO contributes to childhood obesity and severe adult obesity

11 July 2018

1 reference

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A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Circadian rhythms and the regulation of metabolic tissue function and energy homeostasis.

11 July 2018

1 reference

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Health risks associated with overweight and obesity

11 July 2018

1 reference

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Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, hypogonadism, pes cavus, and tremor

11 July 2018

1 reference

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SH2B1 (SH2-B) and JAK2: a multifunctional adaptor protein and kinase made for each other

11 July 2018

1 reference

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Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

11 July 2018

1 reference

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Central nervous system control of food intake and body weight

11 July 2018

1 reference

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Protective effect of brain-derived neurotrophic factor on pancreatic islets in obese diabetic mice

11 July 2018

1 reference

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Thrifty genes for obesity and the metabolic syndrome--time to call off the search?

11 July 2018

1 reference

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The human obesity gene map: the 2005 update

11 July 2018

1 reference

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CART peptide diurnal variations in blood and brain

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

The promise of ghrelin antagonism in obesity treatment

11 July 2018

1 reference

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Circadian clocks are resounding in peripheral tissues

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Role of leptin and melanocortin signaling in uremia-associated cachexia

11 July 2018

1 reference

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CART knock out mice have impaired insulin secretion and glucose intolerance, altered beta cell morphology and increased body weight

11 July 2018

1 reference

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Back to the future: genetic correlations, adaptation and speciation

11 July 2018

1 reference

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Obesity and metabolic syndrome in circadian Clock mutant mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Analysis of sequence variability in the CART gene in relation to obesity in a Caucasian population

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

The genetics of human obesity

11 July 2018

1 reference

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Orexigenic and anorexigenic mechanisms in the control of nutrition in chronic kidney disease

11 July 2018

1 reference

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Congenital leptin deficiency due to homozygosity for the Delta133G mutation: report of another case and evaluation of response to four years of leptin therapy

11 July 2018

1 reference

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Alterations in the dynamics of circulating ghrelin, adiponectin, and leptin in human obesity

11 July 2018

1 reference

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Physical activity interventions in the prevention and treatment of paediatric obesity: systematic review and critical appraisal

11 July 2018

1 reference

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The SLC6A14 gene shows evidence of association with obesity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Overweight, Obesity, and Mortality from Cancer in a Prospectively Studied Cohort of U.S. Adults

11 July 2018

1 reference

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Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27,485 people

11 July 2018

1 reference

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Role of the central melanocortin system in cachexia.

11 July 2018

1 reference

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Obesity and the regulation of energy balance

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Genome-wide scan of obesity in Finnish sibpairs reveals linkage to chromosome Xq24

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Leptin-specific patterns of gene expression in white adipose tissue

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Hypothalamic serotonin in control of eating behavior, meal size, and body weight

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

CART peptides in the central control of feeding and interactions with neuropeptide Y.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Hypothalamic CART is a new anorectic peptide regulated by leptin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

A mutation in the human leptin receptor gene causes obesity and pituitary dysfunction

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Congenital leptin deficiency is associated with severe early-onset obesity in humans

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Functional identification of the mouse circadian Clock gene by transgenic BAC rescue

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Positional cloning of the mouse circadian clock gene

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Crystal structure of the obese protein leptin-E100

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Targeted disruption of the melanocortin-4 receptor results in obesity in mice

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Genomewide search for genes influencing percent body fat in Pima Indians: suggestive linkage at chromosome 11q21-q22. Pima Diabetes Gene Group

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

An Adoption Study of Human Obesity

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Body weight in the Finnish Twin Cohort

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Genetic influences on growth traits of BMI: a longitudinal study of adult twins.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

The common rs9939609 gene variant of the fat mass- and obesity-associated gene FTO is related to fat cell lipolysis

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Peripheral administration of the melanocortin-4 receptor antagonist NBI-12i ameliorates uremia-associated cachexia in mice.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Adolescents carrying a missense mutation in the CART gene exhibit increased anxiety and depression

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Rhythmic messenger ribonucleic acid expression of clock genes and adipocytokines in mouse visceral adipose tissue

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10.

24 September 2018

1 reference

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Melatonin effect on rat body weight regulation in response to high-fat diet at middle age.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Is the energy homeostasis system inherently biased toward weight gain?

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Leptin: a review of its peripheral actions and interactions

24 September 2018

1 reference

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Candidate-gene approaches for studying complex genetic traits: practical considerations

24 September 2018

1 reference

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Mutational screening of the CART gene in obese children: identifying a mutation (Leu34Phe) associated with reduced resting energy expenditure and cosegregating with obesity phenotype in a large family

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

The disease burden associated with overweight and obesity

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

A leptin missense mutation associated with hypogonadism and morbid obesity.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

A twin study of human obesity.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3313574

Meta-Analysis of Genome-wide Linkage Studies in BMI and Obesity*

24 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.5402%2F2012%2F536905

Prevalence of Mutations and Functional Analyses of Melanocortin 4 Receptor Variants Identified among 750 Men with Juvenile-Onset Obesity

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.5402%2F2012%2F536905

Effect of obesity on estradiol level, and its relationship to leptin, bone maturation, and bone mineral density in children

21 January 2018

1 reference

12 December 2020

The biological predisposition to obesity: beyond the thrifty genotype scenario

1 reference

12 December 2020

A genome-wide scan for human obesity genes reveals a major susceptibility locus on chromosome 10

1 reference

12 December 2020

Cocaine- and amphetamine-regulated transcript (CART) is colocalized with the orexigenic neuropeptide Y and agouti-related protein and absent from the anorexigenic alpha-melanocyte-stimulating hormone neurons in the infundibular nucleus of the human

1 reference

12 December 2020

Sequencing of the putative promoter region of the cocaine- and amphetamine-regulated-transcript gene and identification of polymorphic sites associated with obesity

1 reference

12 December 2020

Identifiers

DOI

10.5402/2012/536905

1 reference

10 August 2017

1 reference

10 August 2017

PubMed publication ID

22474595

1 reference