Interleukin 1 alpha (Q14878193)

interleukin-1 family

2 references

Transporter Classification Database ID

1.A.109.1.1

hierarchical database ID heuristic

2 October 2019

based on heuristic

interleukin-1 alpha

1 reference

Interleukin-1 propeptide family

1 reference

based on heuristic

inferred from protein domain or family

Interleukin-1 conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

Rebound from nitric oxide inhibition triggers enhanced monocyte activation and chemotaxis

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

8 April 2019

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

protein binding

6 references

8 April 2019

S100A13 mediates the copper-dependent stress-induced release of IL-1α from both human U937 and murine NIH 3T3 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

8 April 2019

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

8 April 2019

Active caspase-1 is a regulator of unconventional protein secretion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

8 April 2019

A proteome-scale map of the human interactome network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

8 April 2019

Widespread macromolecular interaction perturbations in human genetic disorders

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

8 April 2019

Intracellular IL-1alpha-binding proteins contribute to biological functions of endogenous IL-1alpha in systemic sclerosis fibroblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

copper ion binding

1 reference

8 April 2019

S100A13 mediates the copper-dependent stress-induced release of IL-1α from both human U937 and murine NIH 3T3 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

interleukin-1 receptor binding

IBA

interleukin-1 receptor binding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

1 reference

8 April 2019

cell component

cytosol

1 reference

8 April 2019

S100A13 mediates the copper-dependent stress-induced release of IL-1α from both human U937 and murine NIH 3T3 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

extracellular region

cytoplasm

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01583&geneProductId=UniProtKB:P01583

extracellular space

Interleukin 1 is processed and released during apoptosis

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

8 April 2019

cDNA cloning of IL-1 alpha and IL-1 beta from mRNA of U937 cell line

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

8 April 2019

S100A13 mediates the copper-dependent stress-induced release of IL-1α from both human U937 and murine NIH 3T3 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

cellular response to heat

biological process

1 reference

8 April 2019

S100A13 mediates the copper-dependent stress-induced release of IL-1α from both human U937 and murine NIH 3T3 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

response to copper ion

1 reference

8 April 2019

S100A13 mediates the copper-dependent stress-induced release of IL-1α from both human U937 and murine NIH 3T3 cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

positive regulation of gene expression

1 reference

8 April 2019

Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

immune response

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

1 reference

8 April 2019

connective tissue replacement involved in inflammatory response wound healing

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

positive regulation of protein secretion

1 reference

8 April 2019

Regulation of insulin-like growth factor-binding protein-5 by insulin-like growth factor I and interleukin-1alpha in ovine articular chondrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

extrinsic apoptotic signaling pathway in absence of ligand

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

ectopic germ cell programmed cell death

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

cell population proliferation

1 reference

1 January 2018

Cloning and expression of murine interleukin-1 cDNA in Escherichia coli

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

inflammatory response

negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

3 references

1 reference

8 April 2019

A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

positive regulation of mitotic nuclear division

1 reference

8 April 2019

Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

positive regulation of cell division

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

1 reference

8 April 2019

positive regulation of transcription by RNA polymerase II

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

negative regulation of cell population proliferation

1 reference

8 April 2019

cDNA cloning of IL-1 alpha and IL-1 beta from mRNA of U937 cell line

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

apoptotic process

1 reference

8 April 2019

Interleukin 1 is processed and released during apoptosis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

positive regulation of interleukin-6 production

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01583&geneProductId=UniProtKB:P01583

positive regulation of neutrophil extravasation

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01583&geneProductId=UniProtKB:P01583

fever generation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

1 reference

8 April 2019

positive regulation of monocyte chemotactic protein-1 production

1 reference

31 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P01583&geneProductId=UniProtKB:P01583

regulation of signaling receptor activity

1 reference

8 April 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

interleukin-1-mediated signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P01583

1 reference

8 April 2019

Interleukin-1 conserved site

Gene Atlas image

PBB GE IL1A 210118 s at fs.png
732 × 530; 10 KB

0 references

has part(s)

1 reference

Interleukin-1 propeptide

1 reference

Transporter Classification Database ID

Identifiers

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

13 November 2019

1 reference

1 reference

9 August 2016

language of work or name

1 reference

9 August 2016

language of work or name

1 reference

9 August 2016

language of work or name

English

1.A.109.1.1

2 references

Transporter Classification database

13 March 2020

Transporter Classification database