Apoptosis antagonizing transcription factor (Q21116290)

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mammalian protein found in Homo sapiens
  • rb-binding protein Che-1
  • protein AATF
  • AATF
  • Apoptosis-antagonizing transcription factor
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Language Label Description Also known as
English
Apoptosis antagonizing transcription factor
mammalian protein found in Homo sapiens
  • rb-binding protein Che-1
  • protein AATF
  • AATF
  • Apoptosis-antagonizing transcription factor

Statements

molecular function
protein binding
determination method or standard
IPI
7 references
retrieved
8 April 2019
stated in
Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb
GOA
curator
UniProt
UniProt protein ID
Q9NY61
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NY61
determination method or standard
IPI
retrieved
8 April 2019
stated in
Che-1 phosphorylation by ATM/ATR and Chk2 kinases activates p53 transcription and the G2/M checkpoint
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NY61
determination method or standard
IPI
retrieved
8 April 2019
stated in
AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NY61
determination method or standard
IPI
retrieved
8 April 2019
stated in
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NY61
determination method or standard
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NY61
determination method or standard
IPI
retrieved
8 April 2019
stated in
Che-1 arrests human colon carcinoma cell proliferation by displacing HDAC1 from the p21WAF1/CIP1 promoter
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NY61
determination method or standard
IPI
retrieved
8 April 2019
stated in
Che1/AATF interacts with subunits of the histone acetyltransferase core module of SAGA complexes
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NY61
determination method or standard
IPI
cell component
nucleus
determination method or standard
IDA
IEA
7 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
Q9NY61
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NY61
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NY61
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NY61
determination method or standard
IEA
retrieved
8 April 2019
stated in
AATF protects neural cells against oxidative damage induced by amyloid beta-peptide
GOA
curator
UniProt
UniProt protein ID
Q9NY61
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NY61
determination method or standard
IDA
retrieved
8 April 2019
stated in
Functional proteomic analysis of human nucleolus
GOA
curator
UniProt
UniProt protein ID
Q9NY61
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NY61
determination method or standard
IDA
retrieved
8 April 2019
stated in
AATF, a novel transcription factor that interacts with Dlk/ZIP kinase and interferes with apoptosis
GOA
curator
UniProt
UniProt protein ID
Q9NY61
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NY61
determination method or standard
IDA
retrieved
8 April 2019
stated in
AATF inhibits aberrant production of amyloid beta peptide 1-42 by interacting directly with Par-4
GOA
curator
UniProt
UniProt protein ID
Q9NY61
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9NY61
determination method or standard
IDA
biological process

Identifiers

 
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