MDM2 regulates dihydrofolate reductase activity through monoubiquitination (Q24634031)

1

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Paul C Nield

2

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Timothy Devling

3

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Rosalind E Jenkins

4

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B Kevin Park

5

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Radoslaw Polański

6

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Nikolina Vlatković

7

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Mark T Boyd

Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53

8

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language of work or name

English

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publication date

1 May 2008

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published in

Cancer Research

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volume

68

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issue

9

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page(s)

3232-42

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cites work

1 reference

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A novel cellular protein (MTBP) binds to MDM2 and induces a G1 arrest that is suppressed by MDM2

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Protein regulation by monoubiquitin

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Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

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Chemopreventive effects of dietary folate on intestinal polyps in Apc+/-Msh2-/- mice

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Impact of alterations affecting the p53 pathway in bladder cancer on clinical outcome, assessed by conventional and array-based methods

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Expression of the murine double minute gene 2 oncoprotein in esophageal squamous cell carcinoma as a novel marker for lack of response to chemoradiotreatment

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Inactivation of the p53 pathway in prostate cancer: impact on tumor progression

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DNA methylation and cancer

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Dietary folate is associated withp16INK4A methylation in head and neck squamous cell carcinoma

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Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity

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Properties of an altered dihydrofolate reductase encoded by amplified genes in cultured mouse fibroblasts

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12 December 2020

10.1158/0008-5472.CAN-07-5271

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DOI

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release_wjtn6gjic5dqnlecnsjcutigjy

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24 November 2022

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PubMed publication ID

18451149

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