Multisite phosphorylation by Cdk2 and GSK3 controls cyclin E degradation (Q28208407)

2

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Keith R Loeb

3

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Jonathan Grim

4

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Andrew Bloecher

5

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Mark Gurien-West

6

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Bruce E Clurman

7

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James M Roberts

Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation

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language of work or name

English

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publication date

August 2003

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published in

Molecular Cell

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volume

12

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issue

2

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page(s)

381-92

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cites work

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Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

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The renaissance of GSK3

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Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition

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Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization

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Cyclin E in human cancers.

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Association of human cyclin E with a periodic G1-S phase protein kinase

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Developmental control of the G1 to S transition in Drosophila: cyclin Eis a limiting downstream target of E2F

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The transcription factor E2F is required for S phase during Drosophila embryogenesis

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Accumulation of cyclin E is not a prerequisite for passage through the restriction point

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A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p

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A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation

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Phosphorylation-dependent and -independent functions of p130 cooperate to evoke a sustained G1 block.

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Cdk phosphorylation triggers sequential intramolecular interactions that progressively block Rb functions as cells move through G1

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The role of cyclin E in cell proliferation, development and cancer

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A molecular mechanism for the effect of lithium on development

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Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

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Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle

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D-type cyclin-dependent kinase activity in mammalian cells

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Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

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Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

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Regulation of the cyclin E gene by transcription factor E2F1

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Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

14536078

1 reference

Consolidated OpenCitations Corpus – April 2017