The role of oxygen availability in embryonic development and stem cell function (Q33876311)

29 July 2017

1 reference

title

The role of oxygen availability in embryonic development and stem cell function (English)

1 reference

29 July 2017

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M Celeste Simon

1

1 reference

29 July 2017

Brian Keith

series ordinal

2

1 reference

29 July 2017

publication date

20 February 2008

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Nature Reviews Molecular Cell Biology

29 July 2017

published in

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29 July 2017

volume

9

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29 July 2017

issue

4

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29 July 2017

page(s)

285-296

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Directly reprogrammed fibroblasts show global epigenetic remodeling and widespread tissue contribution

29 July 2017

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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5 July 2018

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HIF-dependent hematopoietic factors regulate the development of the embryonic vasculature

5 July 2018

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Regulation of angiogenesis by hypoxia-inducible factor 1.

5 July 2018

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5 July 2018

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5 July 2018

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Lasting longer without oxygen: The influence of hypoxia on Notch signaling

5 July 2018

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Hypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation

5 July 2018

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Hypoxia requires notch signaling to maintain the undifferentiated cell state

5 July 2018

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An expanding role for mTOR in cancer

5 July 2018

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SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells

5 July 2018

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The mammalian unfolded protein response

5 July 2018

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Proline hydroxylation and gene expression

5 July 2018

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Control of the hypoxic response through regulation of mRNA translation.

5 July 2018

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5 July 2018

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Low O2 tensions and the prevention of differentiation of hES cells

5 July 2018

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

5 July 2018

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Deficiency in the p110alpha subunit of PI3K results in diminished Tie2 expression and Tie2(-/-)-like vascular defects in mice

5 July 2018

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5 July 2018

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Oct4 is required for primordial germ cell survival

5 July 2018

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Disruption of the mouse mTOR gene leads to early postimplantation lethality and prohibits embryonic stem cell development

5 July 2018

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EPAS1 promotes adipose differentiation in 3T3-L1 cells

5 July 2018

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Regulation of transcription and translation by hypoxia

5 July 2018

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mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells

5 July 2018

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Oxygen sensing by HIF hydroxylases

5 July 2018

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HIF-1alpha induces cell cycle arrest by functionally counteracting Myc.

5 July 2018

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Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

5 July 2018

1 reference

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Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice

5 July 2018

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Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor

5 July 2018

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Functional Notch signaling is required for BMP4-induced inhibition of myogenic differentiation.

5 July 2018

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Expansion of human SCID-repopulating cells under hypoxic conditions

5 July 2018

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The biology of VEGF and its receptors

5 July 2018

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A novel hypoxia-inducible factor-independent hypoxic response regulating mammalian target of rapamycin and its targets.

5 July 2018

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Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

5 July 2018

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Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

5 July 2018

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Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.

5 July 2018

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FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

5 July 2018

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Pluripotency of mesenchymal stem cells derived from adult marrow

5 July 2018

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Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice

5 July 2018

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Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

5 July 2018

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Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype

5 July 2018

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Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

5 July 2018

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Inhibitory PAS domain protein is a negative regulator of hypoxia-inducible gene expression

5 July 2018

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Hypoxia in cartilage: HIF-1alpha is essential for chondrocyte growth arrest and survival

5 July 2018

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Stem cells find their niche

5 July 2018

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FIH-1: a novel protein that interacts with HIF-1alpha and VHL to mediate repression of HIF-1 transcriptional activity

5 July 2018

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A conserved family of prolyl-4-hydroxylases that modify HIF

5 July 2018

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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

5 July 2018

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Independent function of two destruction domains in hypoxia-inducible factor-alpha chains activated by prolyl hydroxylation

5 July 2018

1 reference

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Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology

5 July 2018

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HIF-1alpha binding to VHL is regulated by stimulus-sensitive proline hydroxylation

5 July 2018

1 reference

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Translational control is required for the unfolded protein response and in vivo glucose homeostasis

5 July 2018

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Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

5 July 2018

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Targeted mutation of the murine arylhydrocarbon receptor nuclear translocator 2 (Arnt2) gene reveals partial redundancy with Arnt

5 July 2018

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Cultivation of rat marrow-derived mesenchymal stem cells in reduced oxygen tension: effects on in vitro and in vivo osteochondrogenesis

5 July 2018

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HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

5 July 2018

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Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

5 July 2018

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Mop3 is an essential component of the master circadian pacemaker in mammals

5 July 2018

1 reference

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Placental cell fates are regulated in vivo by HIF-mediated hypoxia responses

5 July 2018

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Pluripotent, cytokine-dependent, hematopoietic stem cells are immortalized by constitutive Notch1 signaling

5 July 2018

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HIF-1 and human disease: one highly involved factor

5 July 2018

1 reference

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The transcription factor EPAS-1/hypoxia-inducible factor 2alpha plays an important role in vascular remodeling

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

The PAS superfamily: sensors of environmental and developmental signals

5 July 2018

1 reference

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Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Hypoxia-inducible factor-1 mediates the biological effects of oxygen on human trophoblast differentiation through TGFbeta(3)

5 July 2018

1 reference

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Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Multilineage embryonic hematopoiesis requires hypoxic ARNT activity

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Notch signaling: cell fate control and signal integration in development

5 July 2018

1 reference

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Molecular mechanisms of transcription activation by HLF and HIF1alpha in response to hypoxia: their stabilization and redox signal-induced interaction with CBP/p300.

5 July 2018

1 reference

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Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase

5 July 2018

1 reference

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Notch signaling imposes two distinct blocks in the differentiation of C2C12 myoblasts.

5 July 2018

1 reference

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Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha

5 July 2018

1 reference

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Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4

5 July 2018

1 reference

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The hypoxia-responsive transcription factor EPAS1 is essential for catecholamine homeostasis and protection against heart failure during embryonic development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Oxygen, genes, and development: an analysis of the role of hypoxic gene regulation during murine vascular development.

5 July 2018

1 reference

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HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

5 July 2018

1 reference

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Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1α

5 July 2018

1 reference

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ARNT-deficient mice and placental differentiation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Defective placental vasculogenesis causes embryonic lethality in VHL-deficient mice

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Mechanisms of angiogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Conservation of the Notch signalling pathway in mammalian neurogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

The hypoxic response: huffing and HIFing

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Adaptation of chondrocytes to low oxygen tension: relationship between hypoxia and cellular metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Development of the Drosophila tracheal system occurs by a series of morphologically distinct but genetically coupled branching events

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Toward a molecular understanding of skeletal development

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Purification and characterization of hypoxia-inducible factor 1

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

PPAR gamma 2 regulates adipose expression of the phosphoenolpyruvate carboxykinase gene

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

New type of POU domain in germ line-specific protein Oct-4

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

A vasculature-associated niche for undifferentiated spermatogonia in the mouse testis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Transcriptional regulation of APH-1A and increased gamma-secretase cleavage of APP and Notch by HIF-1 and hypoxia.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Notch signaling in development and disease.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Oxygen-regulated gene expression in bovine blastocysts

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Hypoxia, HIFs, and cardiovascular development.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Delta/Notch signaling promotes formation of zebrafish neural crest by repressing Neurogenin 1 function

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Inhibition of PPAR gamma 2 gene expression by the HIF-1-regulated gene DEC1/Stra13: a mechanism for regulation of adipogenesis by hypoxia

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Comparative analysis of human, bovine, and murine Oct-4 upstream promoter sequences

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Culture in reduced levels of oxygen promotes clonogenic sympathoadrenal differentiation by isolated neural crest stem cells.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Oxygen regulation of airway branching in Drosophila is mediated by branchless FGF.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Expression of ARNT, ARNT2, HIF1 alpha, HIF2 alpha and Ah receptor mRNAs in the developing mouse.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Regulation of Human Placental Development by Oxygen Tension

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

trachealess encodes a bHLH-PAS protein that is an inducer of tracheal cell fates in Drosophila

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Tubulogenesis in Drosophila: a requirement for the trachealess gene product

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD.

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2876333

Intrauterine Oxygen Tension During the Estrous Cycle in the Rat: Its Relation to Uterine Respiration and Vascular Activity

29 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNRM2354

Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNRM2354

Hypoxia affects mesoderm and enhances hemangioblast specification during early development

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNRM2354

Effect of oxygen concentration on morphogenesis of cranial neural folds and neural crest in cultured rat embryos

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18285802

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18285802

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of hypoxia in the maintenance of hematopoietic stem cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18285802

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NRM2354

1 reference

Dimensions Publication ID

29 July 2017

0 references

1 reference

29 July 2017

1 reference