Mechanisms of cyclin-dependent kinase inactivation by progestins (Q33993962)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9528753%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

title

Mechanisms of cyclin-dependent kinase inactivation by progestins (English)

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10 November 2019

2

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10 November 2019

author name string

E A Musgrove

1

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10 November 2019

C S Lee

3

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10 November 2019

A L Cornish

4

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10 November 2019

R L Sutherland

5

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10 November 2019

language of work or name

English

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publication date

1 April 1998

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Molecular and Cellular Biology

10 November 2019

published in

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10 November 2019

volume

18

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10 November 2019

issue

4

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10 November 2019

page(s)

1812-1825

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Breast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52,705 women with breast cancer and 108,411 women without breast cancer. Collaborative Group on Hormonal Factors in Breast Cancer

10 November 2019

cites work

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p21CIP1 and Cdc25A: competition between an inhibitor and an activator of cyclin-dependent kinases

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Repression of the CDK activator Cdc25A and cell-cycle arrest by cytokine TGF-beta in cells lacking the CDK inhibitor p15

5 July 2018

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New functional activities for the p21 family of CDK inhibitors

5 July 2018

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Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2.

5 July 2018

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The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2

5 July 2018

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5 July 2018

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The consensus motif for phosphorylation by cyclin D1-Cdk4 is different from that for phosphorylation by cyclin A/E-Cdk2

5 July 2018

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Antiprogestin inhibition of cell cycle progression in T-47D breast cancer cells is accompanied by induction of the cyclin-dependent kinase inhibitor p21.

5 July 2018

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Growth arrest by the cyclin-dependent kinase inhibitor p27Kip1 is abrogated by c-Myc

5 July 2018

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The dynamics of cyclin dependent kinase structure

5 July 2018

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Cdc25 cell-cycle phosphatase as a target of c-myc

5 July 2018

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Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

5 July 2018

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Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest

5 July 2018

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Breast cancer and hormonal contraceptives: collaborative reanalysis of individual data on 53 297 women with breast cancer and 100 239 women without breast cancer from 54 epidemiological studies

5 July 2018

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Redistribution of the CDK inhibitor p27 between different cyclin.CDK complexes in the mouse fibroblast cell cycle and in cells arrested with lovastatin or ultraviolet irradiation

5 July 2018

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Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression

5 July 2018

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Cdc25A is a novel phosphatase functioning early in the cell cycle

5 July 2018

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Effects of c-myc expression on cell cycle progression.

5 July 2018

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Cyclin D1 induction in breast cancer cells shortens G1 and is sufficient for cells arrested in G1 to complete the cell cycle

5 July 2018

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p21-containing cyclin kinases exist in both active and inactive states

5 July 2018

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Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

5 July 2018

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G1 phase progression: cycling on cue

5 July 2018

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Principles of CDK regulation

5 July 2018

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Cell cycle control by steroid hormones

5 July 2018

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5 July 2018

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Novel INK4 proteins, p19 and p18, are specific inhibitors of the cyclin D-dependent kinases CDK4 and CDK6

5 July 2018

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The role of TGF-beta production in growth inhibition of breast-tumor cells by progestins.

5 July 2018

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5 July 2018

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Both p16 and p21 families of cyclin-dependent kinase (CDK) inhibitors block the phosphorylation of cyclin-dependent kinases by the CDK-activating kinase

5 July 2018

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5 July 2018

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5 July 2018

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Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition

5 July 2018

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Abrogation of p53-induced cell cycle arrest by c-Myc: evidence for an inhibitor of p21WAF1/CIP1/SDI1.

5 July 2018

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Growth inhibition and increase of insulin receptors in antiestrogen-resistant T47DCO human breast cancer cells by progestins: implications for endocrine therapies

5 July 2018

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Effect of medroxyprogesterone acetate on proliferation and cell cycle kinetics of human mammary carcinoma cells

5 July 2018

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Endocrine treatment of breast cancer in women

5 July 2018

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Progestin regulation of cellular proliferation

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121411

p55CDC25 is a nuclear protein required for the initiation of mitosis in human cells.

5 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121411

Progestins both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor alpha, epidermal growth factor receptor, c-fos, and c-myc genes

5 July 2018

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Differential regulation of c-myc by progestins and antiestrogens in T-47D human breast cancer cells

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=121411

Cell type and differentiation dependent heterogeneity in retinoblastoma protein expression in SCID mouse fetuses

5 July 2018

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Cell cycle regulation of CDK2 activity by phosphorylation of Thr160 and Tyr15

5 July 2018

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p21 contains independent binding sites for cyclin and cdk2: both sites are required to inhibit cdk2 kinase activity.

5 July 2018

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Regulated expression of the retinoblastoma gene in differentiating embryonal carcinoma cells.

29 October 2018

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Antiestrogenic effect of R5020, a synthetic progestin in human breast cancer cells in culture.

29 October 2018

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Antiestrogen inhibition of cell cycle progression in breast cancer cells in associated with inhibition of cyclin-dependent kinase activity and decreased retinoblastoma protein phosphorylation

29 October 2018

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The Use of Estrogens and Progestins and the Risk of Breast Cancer in Postmenopausal Women

29 October 2018

1 reference

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Increased retinoblastoma gene expression is associated with late stages of differentiation in many different cell types

29 October 2018

1 reference

12 December 2020

Stimulation of c-myc oncogene expression associated with estrogen-induced proliferation of human breast cancer cells

1 reference

12 December 2020

Collaboration of G1 cyclins in the functional inactivation of the retinoblastoma protein

1 reference

12 December 2020

Expression and amplification of cyclin genes in human breast cancer

1 reference

12 December 2020

17beta-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer cells

1 reference

12 December 2020

Endometrial carcinoma

1 reference

12 December 2020

Estrogen regulates activity of cyclin-dependent kinases and retinoblastoma protein phosphorylation in breast cancer cells

1 reference

12 December 2020

Cytoplasmic accumulation of cdc25B phosphatase in mitosis triggers centrosomal microtubule nucleation in HeLa cells

1 reference

12 December 2020

Formation of p27-CDK complexes during the human mitotic cell cycle

1 reference

12 December 2020

Inducible expression of cyclin D1 in T-47D human breast cancer cells is sufficient for Cdk2 activation and pRB hyperphosphorylation

1 reference

12 December 2020

Myc activation of cyclin E/Cdk2 kinase involves induction of cyclin E gene transcription and inhibition of p27(Kip1) binding to newly formed complexes

1 reference

12 December 2020

Cdk2-dependent phosphorylation of p27 facilitates its Myc-induced release from cyclin E/cdk2 complexes

1 reference

12 December 2020

c-Myc or cyclin D1 mimics estrogen effects on cyclin E-Cdk2 activation and cell cycle reentry

1 reference

12 December 2020

Identifiers

DOI

10.1128/MCB.18.4.1812

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9528753%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9528753%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PubMed publication ID

9528753

1 reference