Soluble Urokinase Receptor Is Released Selectively by Glioblastoma Cells That Express Epidermal Growth Factor Receptor Variant III and Promotes Tumor Cell Migration and Invasion (Q35721585)

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scientific article published on 2 April 2015

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English	Soluble Urokinase Receptor Is Released Selectively by Glioblastoma Cells That Express Epidermal Growth Factor Receptor Variant III and Promotes Tumor Cell Migration and Invasion	scientific article published on 2 April 2015

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Soluble Urokinase Receptor Is Released Selectively by Glioblastoma Cells That Express Epidermal Growth Factor Receptor Variant III and Promotes Tumor Cell Migration and Invasion (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

1 reference

based on heuristic

inferred from title

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based on heuristic

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Andrew S. Gilder

object named as

Andrew S Gilder

1

0 references

object named as

Karra A Jones

2

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author name string

Jingjing Hu

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Lei Wang

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Clark C Chen

5

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Bob S Carter

6

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Europe PubMed Central

PubMed publication ID

9 August 2017

Steven L Gonias

7

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Europe PubMed Central

PubMed publication ID

9 August 2017

language of work or name

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publication date

2 April 2015

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Europe PubMed Central

PubMed publication ID

9 August 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

9 August 2017

290

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Europe PubMed Central

PubMed publication ID

9 August 2017

24

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Europe PubMed Central

PubMed publication ID

9 August 2017

14798-14809

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4463428/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

A urokinase receptor-Bim signaling axis emerges during EGFR inhibitor resistance in mutant EGFR glioblastoma

1 reference

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Neutralizing the EGF receptor in glioblastoma cells stimulates cell migration by activating uPAR-initiated cell signaling.

1 reference

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12 July 2018

MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma

1 reference

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12 July 2018

EGFR variant heterogeneity in glioblastoma resolved through single-nucleus sequencing

1 reference

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12 July 2018

Phospholipase D2 mediates survival signaling through direct regulation of Akt in glioblastoma cells

1 reference

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12 July 2018

The somatic genomic landscape of glioblastoma

1 reference

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12 July 2018

Tumor-associated soluble uPAR-directed endothelial cell motility and tumor angiogenesis

1 reference

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Soluble urokinase plasminogen activator receptor is associated with inflammation in the vulnerable human atherosclerotic plaque

1 reference

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12 July 2018

Crosstalk between the urokinase-type plasminogen activator receptor and EGF receptor variant III supports survival and growth of glioblastoma cells

1 reference

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Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis

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12 July 2018

Regulation of the urokinase receptor (uPAR) by LDL receptor-related protein-1 (LRP1).

1 reference

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12 July 2018

Heterogeneity maintenance in glioblastoma: a social network

1 reference

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12 July 2018

Analysis of phosphotyrosine signaling in glioblastoma identifies STAT5 as a novel downstream target of ΔEGFR.

1 reference

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12 July 2018

Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma

1 reference

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12 July 2018

Mutant EGFR is required for maintenance of glioma growth in vivo, and its ablation leads to escape from receptor dependence

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12 July 2018

Regulation of cell signalling by uPAR.

1 reference

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12 July 2018

Multiple activities of a multifaceted receptor: roles of cleaved and soluble uPAR.

1 reference

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Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness

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Association of the circulating levels of the urokinase system of plasminogen activation with the presence of prostate cancer and invasion, progression, and metastasis.

1 reference

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An uncleavable uPAR mutant allows dissection of signaling pathways in uPA-dependent cell migration.

1 reference

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Neural stem cells and the origin of gliomas

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12 July 2018

Domain 2 of the urokinase receptor contains an integrin-interacting epitope with intrinsic signaling activity: generation of a new integrin inhibitor

1 reference

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12 July 2018

Dynamic assembly of the urokinase-type plasminogen activator signaling receptor complex determines the mitogenic activity of urokinase-type plasminogen activator.

1 reference

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12 July 2018

Prognostic value of epidermal growth factor receptor in patients with glioblastoma multiforme

1 reference

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12 July 2018

Soluble urokinase-type plasminogen activator receptor inhibits cancer cell growth and invasion by direct urokinase-independent effects on cell signaling

1 reference

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12 July 2018

uPAR: a versatile signalling orchestrator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463428

12 July 2018

The cleavage of the urokinase receptor regulates its multiple functions

1 reference

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The fibrinolytic receptor for urokinase activates the G protein-coupled chemotactic receptor FPRL1/LXA4R.

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Urokinase-type plasminogen activator receptor (CD87) is a ligand for integrins and mediates cell-cell interaction.

1 reference

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The plasminogen (fibrinolytic) system

1 reference

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Soluble urokinase receptor released from human carcinoma cells: a plasma parameter for xenograft tumour studies.

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12 July 2018

Intratumoral cytogenetic heterogeneity detected by comparative genomic hybridization and laser scanning cytometry in human gliomas

1 reference

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12 July 2018

A urokinase-sensitive region of the human urokinase receptor is responsible for its chemotactic activity.

1 reference

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The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling

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12 July 2018

Regulation of integrin function by the urokinase receptor

1 reference

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Differential expression of the urokinase receptor in fibroblasts from normal and fibrotic human lungs

1 reference

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Proteolytic cleavage of the urokinase receptor substitutes for the agonist-induced chemotactic effect

1 reference

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An alternatively spliced variant of mRNA for the human receptor for urokinase plasminogen activator

1 reference

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12 July 2018

A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

1 reference

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12 July 2018

Expression of the receptor for urokinase-type plasminogen activator in normal and neoplastic blood cells and hematopoietic tissue

1 reference

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12 July 2018

Expression of epidermal growth factor receptors in human brain tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463428

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Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

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Evaluating the value of uPAR of serum and tissue on patients with cervical cancer.

1 reference

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25 September 2018

Detection of EGFRvIII mutant DNA in the peripheral blood of brain tumor patients

1 reference

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25 September 2018

Increased plasma soluble uPAR level is a risk marker of respiratory cancer in initially cancer-free individuals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463428

25 September 2018

Urokinase receptor primes cells to proliferate in response to epidermal growth factor

1 reference

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25 September 2018

Soluble urokinase-type plasminogen activator receptor (suPAR) as an independent factor predicting worse prognosis and extra-bone marrow involvement in multiple myeloma patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463428

25 September 2018

EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463428

25 September 2018

Serum level of soluble urokinase-type plasminogen activator receptor is a strong and independent predictor of survival in human immunodeficiency virus infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4463428

25 September 2018

The murine receptor for urokinase-type plasminogen activator is primarily expressed in tissues actively undergoing remodeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/25837250

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Involvement of the urokinase-type plasminogen activator receptor in hematopoietic stem cell mobilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/25837250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Soluble urokinase plasminogen activator receptor (suPAR) for assessment of disease severity in ventilator-associated pneumonia and sepsis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25837250

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inferred from PubMed ID database lookup

Vascular endothelial growth factor increases urokinase receptor expression in vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25837250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Circulating soluble urokinase plasminogen activator is elevated in patients with chronic liver disease, discriminates stage and aetiology of cirrhosis and predicts prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/25837250

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based on heuristic

inferred from PubMed ID database lookup

Migration of arterial wall cells. Expression of plasminogen activators and inhibitors in injured rat arteries

1 reference

https://pubmed.ncbi.nlm.nih.gov/25837250

12 December 2020

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1 reference

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Soluble urokinase plasminogen activator receptor as a useful biomarker to predict the response to adalimumab in patients with rheumatoid arthritis in a Japanese population

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Shedding and cleavage of the urokinase receptor (uPAR): identification and characterisation of uPAR fragments in vitro and in vivo

1 reference

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12 December 2020

based on heuristic

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Prognostic significance of soluble urokinase plasminogen activator receptor in serum and cytosol of tumor tissue from patients with primary breast cancer

1 reference

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12 December 2020

based on heuristic

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Prognostic and predictive value of intact and cleaved forms of the urokinase plasminogen activator receptor in metastatic prostate cancer

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular glycosylphosphatidylinositol-specific phospholipase D regulates urokinase receptor shedding and cell surface expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/25837250

12 December 2020

based on heuristic

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Functional characterization of an EGF receptor with a truncated extracellular domain expressed in glioblastomas with EGFR gene amplification

1 reference

https://pubmed.ncbi.nlm.nih.gov/25837250

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleaved forms of the urokinase plasminogen activator receptor in plasma have diagnostic potential and predict postoperative survival in patients with ovarian cancer

1 reference

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based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M115.637488

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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