Achieving antigen-specific tolerance in diabetes: regulating specifically (Q36327351)

13 August 2017

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title

Achieving antigen-specific tolerance in diabetes: regulating specifically (English)

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13 August 2017

3

Kevan C Herold

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13 August 2017

2

Jeffrey A Bluestone

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13 August 2017

Wei Chen

1

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13 August 2017

publication date

1 September 2005

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International Reviews of Immunology

13 August 2017

published in

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13 August 2017

volume

24

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13 August 2017

issue

5-6

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13 August 2017

page(s)

287-305

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Autoimmunity versus horror autotoxicus: the struggle for recognition

13 August 2017

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Back to central tolerance

21 January 2018

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The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes.

21 January 2018

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Evidence for a primary islet autoantigen (preproinsulin 1) for insulitis and diabetes in the nonobese diabetic mouse

21 January 2018

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Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice

21 January 2018

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Prevention of diabetes in BB/Wor rats by intrathymic islet injection

21 January 2018

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Induction of tolerance to autoimmune diabetes with islet antigens

21 January 2018

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The cellular mechanism of Aire control of T cell tolerance.

21 January 2018

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Projection of an immunological self shadow within the thymus by the aire protein

21 January 2018

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Positional cloning of the APECED gene

21 January 2018

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Immunochemical characterization of a novel mitochondrially located protein encoded by a nuclear gene within the DFNB8/10 critical region on 21q22.3

21 January 2018

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Regulatory T cells under scrutiny

21 January 2018

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Suppressor T cells--they're back and critical for regulation of autoimmunity!

21 January 2018

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"Infectious" transplantation tolerance.

21 January 2018

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Autoimmune diabetes and the circle of tolerance

21 January 2018

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Effects of insulin in relatives of patients with type 1 diabetes mellitus

21 January 2018

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Use of inhaled insulin in a basal/bolus insulin regimen in type 1 diabetic subjects: a 6-month, randomized, comparative trial

21 January 2018

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Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice

21 January 2018

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CD3-specific antibody-induced active tolerance: from bench to bedside

21 January 2018

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In vitro characterization of five humanized OKT3 effector function variant antibodies.

21 January 2018

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A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes

21 January 2018

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Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus

21 January 2018

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Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

21 January 2018

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TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes

21 January 2018

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Transplantation of cultured islets from two-layer preserved pancreases in type 1 diabetes with anti-CD3 antibody

21 January 2018

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Activation of human T cells by FcR nonbinding anti-CD3 mAb, hOKT3gamma1(Ala-Ala).

21 January 2018

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

21 January 2018

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Foxp3 and natural regulatory T cells: key to a cell lineage?

21 January 2018

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The origin of FOXP3-expressing CD4+ regulatory T cells: thymus or periphery

21 January 2018

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Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25– T cells

21 January 2018

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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

21 January 2018

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

21 January 2018

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

21 January 2018

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Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells

21 January 2018

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CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

21 January 2018

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A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3.

21 January 2018

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CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.

21 January 2018

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Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells

21 January 2018

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Antigen-bearing immature dendritic cells induce peptide-specific CD8(+) regulatory T cells in vivo in humans

21 January 2018

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An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection.

21 January 2018

1 reference

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T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection.

21 January 2018

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T cell inactivation and cytokine deviation promoted by anti-CD3 mAbs

21 January 2018

1 reference

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The specific regulation of immune responses by CD8+ T cells restricted by the MHC class Ib molecule, Qa-1.

21 January 2018

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Definition of target antigens for naturally occurring CD4(+) CD25(+) regulatory T cells

21 January 2018

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In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes

21 January 2018

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In vivo instruction of suppressor commitment in naive T cells

21 January 2018

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Natural versus adaptive regulatory T cells

21 January 2018

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Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

21 January 2018

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Type 1 T regulatory cells.

21 January 2018

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Distinct roles of CTLA-4 and TGF-beta in CD4+CD25+ regulatory T cell function

21 January 2018

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Role of LAG-3 in regulatory T cells.

21 January 2018

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Tolerization of dendritic cells by T(S) cells: the crucial role of inhibitory receptors ILT3 and ILT4

21 January 2018

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Generation and function of antigen-specific suppressor and regulatory T cells

21 January 2018

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Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

21 January 2018

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Achieving antigen-specific immune regulation

21 January 2018

1 reference

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Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes

21 January 2018

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Aerosol insulin induces regulatory CD8 gamma delta T cells that prevent murine insulin-dependent diabetes

21 January 2018

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Suppression of diabetes in nonobese diabetic mice by oral administration of porcine insulin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500379671

Coupling of peripheral tolerance to endogenous interleukin 10 promotes effective modulation of myelin-activated T cells and ameliorates experimental allergic encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500379671

Regulatory T cells and tolerogenic dendritic cells: from basic biology to clinical applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500379671

Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500379671

Macrophages and the regulation of self-reactive T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500379671

Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500379671

In vitro-expanded human CD4(+)CD25(+) T-regulatory cells can markedly inhibit allogeneic dendritic cell-stimulated MLR cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500379671

TCR stimulation with modified anti-CD3 mAb expands CD8+ T cell population and induces CD8+CD25+ Tregs

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500379671

Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08830180500379671

10.1080/08830180500379671

21 January 2018

Identifiers

DOI

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release_lwx2p2wakrf3vnanstpl64ivmy

13 August 2017

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24 November 2022

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