Genetic effects of deoxyribonucleotide pool imbalances (Q40252182)

18 September 2017

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title

Genetic effects of deoxyribonucleotide pool imbalances (English)

1 reference

18 September 2017

Kunz BA

1

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18 September 2017

publication date

1 January 1982

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Environmental Mutagenesis

18 September 2017

published in

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18 September 2017

volume

4

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18 September 2017

issue

6

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18 September 2017

page(s)

695-725

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DNA synthesis with methylated poly(dC-dG) templates. Evidence for a competitive nature to miscoding by

18 September 2017

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Effect of mutagens, chemotherapeutic agents and defects in DNA repair genes on recombination in F′ part6ial diploid Escherichia coli

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Facilitation by pyrimidine deoxyribonucleosides and hypoxanthine of mutagenic and cytotoxic effects of monofunctional alkylating agents in Chinese hamster cells

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Deoxyribonucleoside triphosphate pools and differential thymidine sensitivities of cultured mouse lymphoma and myeloma cells

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Cellular and mitochondrial effects of folate antagonism by pyrimethamine in Saccharomyces cerevisiae.

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Influence of the nuclear gene tmp3 on the loss of mitochondrial genes in Saccharomyces cerevisiae

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The selection and induction of 5-IODO-2-deoxyuridine and thymidine variants of P388 mouse lymphoma cells with agents which are used for selection

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7 January 2021

The genotoxic potential of bases and nucleosides

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7 January 2021

Human disorders showing increased sensitivity to the induction of genetic damage

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7 January 2021

Bromodeoxyuridine mutagenesis, ribonucleotide reductase activity, and deoxyribonucleotide pools in hydroxyurea-resistant mutants.

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7 January 2021

Selection of mammalian thymidine auxotrophic cell mutants defective in thymidylate synthase by their reduced sensitivity to methotrexate

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7 January 2021

Cytogenetic activities of 3 sulphonamides

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7 January 2021

The U.V.-x-ray synergism in Escherichia coli B-r. I. Inhibition by the incorporation of 5-bromouracil and by purine starvation

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7 January 2021

Genetic and biochemical consequences of thymidylate stress.

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7 January 2021

Intracellular thymidine triphosphate concentrations in wild type and in thymine requiring mutants of Escherichia coli 15 and K12.

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7 January 2021

STUDIES ON THE MECHANISM OF THE EFFECT OF FLUORODEOXYURIDINE ON CHROMOSOMES

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7 January 2021

A Reduced Oxygen Enhancement Ratio for X-ray Survival of HeLa Cells in vitro, after Treatment with ‘Methotrexate’

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7 January 2021

STUDIES ON SYNCHRONOUS DIVISION OF TISSUE CULTURE CELLS INITIATED BY EXCESS THYMIDINE

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7 January 2021

An evaluation of the double thymidine block for synchronizing mammalian cells at the G1-S border*1

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7 January 2021

Gene amplification in methotrexate-resistant mouse cells. II. Rearrangement and amplification of non-dihydrofolate reductase gene sequences accompany chromosomal changes

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Mutagenicity of thymidine to cultured Chinese hamster cells

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Loss of deoxyribonucleic acid-thymine during thymine starvation of Escherichia coli.

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7 January 2021

"Thymineless death" in a strain of Saccharomyces cerevisiae auxotrophic for deoxythymidine-5'-monophosphate

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7 January 2021

Excess thymidine is not mutagenic in Chinese hamster V79 fibroblasts.

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7 January 2021

Effects of metabolic inhibitors on cel lethality and mutation induction in Chinese hamster cells. II. The effect of posttreatment with non-toxic concentrations of thymidine

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7 January 2021

Complete Mutagenesis in a Bacterial Population induced by Thymine Starvation on Solid Media

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7 January 2021

Mutations as possible replication errors in bacteria growing under conditions of thymine deficiency

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7 January 2021

Mutagenesis in Escherichia coli. II. Evidence for a common pathway for mutagenesis by ultraviolet light, ionizing radiation and thymine deprivation

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7 January 2021

The metabolism of purines in Aerobacter aerogenes: a study of purineless mutants

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7 January 2021

The role of gene dosage and genetic transpositions in carcinogenesis

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7 January 2021

Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: Possible role of nucleoside kinase(s)

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7 January 2021

Deoxyguanosine Triphosphate as a Possible Toxic Metabolite in the Immunodeficiency Associated with Purine Nucleoside Phosphorylase Deficiency

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7 January 2021

Deoxyadenosine triphosphate as a potentially toxic metabolite in adenosine deaminase deficiency

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

STUDIES ON UNBALANCED GROWTH IN ESCHERICHIA COLI

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Studies on the induction of thymine deficiency and on the effects of thymine and thymidine analogues in Escherichia coli.

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

THE MODE OF ACTION OF 5-FLUOROURACIL AND ITS DERIVATIVES

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Studies in Mutagenesis: Bacterial Mutation induced by Thymine Starvation

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Requirement of GTP for pteridine synthesis in Salmonella typhimurium and its inhibition by AMP.

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Bromodeoxyuridine mutagenesis in mammalian cells is stimulated by thymidine and suppressed by deoxycytidine

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Induction of sister chromatid exchanges by BUdR is largely independent of the BUdR content of DNA

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Thymine-requiring mutants of the insect pathogen Bacillus thuringiensis

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Congenital malformation due to attempted abortion with aminopterin.

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

TRANSFORMABLE THYMINE-REQUIRING MUTANT OF BACILLUS SUBTILS.

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Purine mutants of mammalian cell lines. II. Identification of a phosphoribosylpyrophosphate amidotransferase-deficient mutant of Chinese hamster lung cells

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7 January 2021

Fidelity of replication of phage phi X174 DNA by DNA polymerase III holoenzyme: spontaneous mutation by misincorporation

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7 January 2021

DNA polymerase accuracy and spontaneous mutation rates: frequencies of purine.purine, purine.pyrimidine, and pyrimidine.pyrimidine mismatches during DNA replication

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7 January 2021

Induction of virus synthesis in polyoma-transformed cells by DNA antimetabolites and by irradiation after pretreatment with 5-bromodeoxyuridine

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7 January 2021

Mutagenicity of thymidine in Chinese hamster cells?

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Stimulation of nuclease activity by thymine starvation

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7 January 2021

MEASUREMENT OF THE STABILITY OF THE REPRESSOR OF ALKALINE PHOSPHATASE SYNTHESIS IN ESCHERICHIA COLI

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Relationship between thymineless death and ultraviolet inactivation in Escherichia coli

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7 January 2021

Enhanced mitotic recombination in a ligase-defective mutant of the yeast Saccharomyces cerevisiae

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Lack of SOS repair in Streptococcus pneumoniae

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7 January 2021

CYTOLOGICAL EVIDENCE FOR CROSSING-OVER IN VITRO IN HUMAN LYMPHOID CELLS.

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7 January 2021

Methotrexate-induced misincorporation of uracil into DNA.

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7 January 2021

Pyrimidine starvation induced by adenosine in fibroblasts and lymphoid cells: role of adenosine deaminase.

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7 January 2021

Neurospora prototroph selection system for studying aneuploid production

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7 January 2021

Deoxyguanosine toxicity in a mouse T lymphoma: Relationship to purine nucleoside phosphorylase-associated immune dysfunction

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7 January 2021

Diphtheria toxin resistance in human fibroblast cell strains from normal and cancer-prone individuals

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7 January 2021

An in vitro transversion by a mutationally altered T4-induced DNA polymerase

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7 January 2021

DNA Repair in Bacteria and Mammalian Cells

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7 January 2021

Chromosome aberrations in metaphase II-oocytes. Stage sensitivity in the mouse oogenesis to amethopterin and cyclophosphamide.

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7 January 2021

Recombination of uracil-containing lambda bacteriophages

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7 January 2021

Growth inhibition of Candida albicans by folate pathway inhibitors. Their potential in the selection of auxotrophs

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7 January 2021

Induction of point mutations by different chemical mechanisms in the liver microsomal assay

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7 January 2021

Fidelity of DNA replication catalysed in vitro on a natural DNA template by the T4 bacteriophage multi-enzyme complex

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7 January 2021

Single-strand breaks in deoxyribonucleic acid and viability loss during deoxyribonucleic acid synthesis inhibition in Escherichia coli

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7 January 2021

Deoxyribonucleotide pools, base pairing, and sequence configuration affecting bromodeoxyuridine- and 2-aminopurine-induced mutagenesis

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7 January 2021

Growth rate and cell kill

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7 January 2021

PERSISTENT NUCLEOLI IN ANIMAL CELLS FOLLOWING TREATMENTS WITH FLUORODEOXYURIDINE AND THYMIDINE

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7 January 2021

Chromosome Studies in Patients Treated With Azathioprine and Amethopterin

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7 January 2021

Cytogenetic effects of methotrexate on human cells in vivo: comparison between results obtained by chromosome studies on bone-marrow cells and blood lymphocytes and by the micronucleus test

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7 January 2021

The apparent mutagenicity of thymine deficiency

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7 January 2021

SENSITIZATION OF PURINE-STARVED BACTERIA TO X-RAYS

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7 January 2021

Bromodeoxyuridine mutagenesis in mammalian cells: mutagenesis is independent of the amount of bromouracil in DNA

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7 January 2021

Bromodeoxyuridine mutagenesis in mammalian cells is stimulated by purine deoxyribonucleosides

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes

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7 January 2021

Effect of Chemotherapeutic Agents on Chromosomes of Patients with Lung Cancer

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7 January 2021

Cell viability and nucleic acid metabolism after exposure of HeLa cells to excess thymidine and deoxyadenosine

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7 January 2021

REPLICATIVE FRAGMENTATION IN T4 BACTERIOPHAGE DNA. II. BIPARENTAL MOLECULAR RECOMBINATION

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7 January 2021

Single-strand binding protein enhances fidelity of DNA synthesis in vitro

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7 January 2021

Induction of mitotic recombination in yeast by starvation for thymine nucleotides

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7 January 2021

A simple, rapid plate assay for mitotic recombination

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7 January 2021

Phenomenology and genetic control of mitotic recombination in yeast

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7 January 2021

The effect of some purine deoxyribosides on the incorporation of [14C] formate and [32P] orthophosphate into DNA of ascites tumor cells in vitro

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7 January 2021

Nucleic acid metabolism in yeast. I. Inhibition of RNA and DNA synthesis by high concentrations of exogenous deoxythymidine 5'-monophosphate in 5'-dTMP low requiring strains

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7 January 2021

Mechanism of adenine toxicity in Escherichia coli

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

The effect of 5-bromouracil on recombination of phage lambda

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Isolation and characterization of yeast mutants auxotrophic for 2′-deoxythymidine 5′-monophosphate

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7 January 2021

Isolation and Properties of a Thymidylate-less Mutant in Saccharomyces cerevisiae

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7 January 2021

Ten model mutagens evaluated by the micronucleus test

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7 January 2021

On the nature of a sparing effect by thymidine on the utilization of deoxycytidine

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7 January 2021

Comparison of the Relative Mutagenic Activity for Eight Antineoplastic Drugs in the Ames Salmonella/Microsome and TK+/− Mouse Lymphoma Assays

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7 January 2021

Multienzyme complexes in DNA precursor biosynthesis

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7 January 2021

Thymineless death of Staphylococcus aureus and formation of its alpha toxin

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7 January 2021

Isolation and biochemical characterization of folate deficient mutants of chinese hamster cells

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7 January 2021

Characterization of a chinese hamster cell with a temperature-sensitive mutation in folate metabolism

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7 January 2021

Congenital anomalies due to attempted abortion with 4-aminopteroglutamic acid

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Role of deoxynucleoside triphosphate pools in the cytotoxic and mutagenic effects of DNA alkylating agents

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Deoxyribonucleotide Pools in Mouse-Fibroblast Cell Lines with Altered Ribonucleotide Reductase

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Induction of a deoxycytidineless state in cultured mammalian cells by bromodeoxyuridine

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Alterations leading to increased ribonucleotide reductase in cells selected for resistance to deoxynucleosides.

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Characterization of a mutator gene in Chinese hamster ovary cells

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Modification of Mitosis by Chemicals

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Methotrexate-induced congenital malformations

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Nuclear morphology of yeast under thymidylate starvation

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Cytological aberrations produced by methotrexate in mouse ascites tumours

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Studies on the acid-soluble nucleotide pool in thymine-requiring mutants of Escherichia coli during thymine starvation. II. Changes in the amounts of deoxycytidine triphosphate and deoxyadenosine triphosphate in Escherichia coli 15 T-A-U

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Mutagenicity of carcinogenic methylating agents is associated with a specific DNA modification

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Yeast transformation: a model system for the study of recombination

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7 January 2021

Gene-amplification model of carcinogenesis

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7 January 2021

Thymidine teratogenesis and mutagenesis inDrosophila melanogaster

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7 January 2021

On the teratogenic effect of thymidine and its suppression by deoxycytidine inDrosophila melanogaster

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7 January 2021

Detection of mitotic and meiotic aneuploidy in the yeast Saccharomyces cerevisiae

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7 January 2021

ATAXIA TELANGIECTASIA: An Inherited Human Disorder Involving Hypersensitivity to Ionizing Radiation and Related DNA-Damaging Chemicals

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7 January 2021

Nonconservative DNA replication in bacteria after thymine starvation

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7 January 2021

Asymmetric Okazaki piece synthesis during replication of simian virus 40 DNA in vivo

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7 January 2021

Mutagenesis of Chinese hamster cells is facilitated by thymidine and deoxycytidine

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7 January 2021

Unequal meiotic recombination within tandem arrays of yeast ribosomal DNA genes

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7 January 2021

Dislodgement and thymineless elimination of N-group plasmids

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7 January 2021

INDUCTION OF REPLICATION BY THYMINE STARVATION AT THE CHROMOSOME ORIGIN IN ESCHERICHIA COLI

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https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

On the mechanism of mitotic recombination in Aspergillus nidulans. I. Intragenic recombination and DNA replication

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Sequential loss of loci in thymine-starved Bacillus subtilis 168 cells. Evidence for a circular chromosome

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

The thymineless death and deoxyribosideless death in lactobacillus acidophilus R-26

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

The effect of thymine starvation on chromosomal structure of Escherichia coli JG-151.

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Loss of DNA behind the growing point of thymine-starved Bacillus subtilis 168

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

The effect of chemicals on induction of recombination in an F' histidine merozygote of Escherichia coli

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Transversion mutagenesis in bacteriophage T4

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Effect of 5-fluorouracil and 5-fluorouridine on metaphase chromosome structure in human lymphoid cells

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Chromosomal abnormalities produced by folic acid antagonists

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Repair of O6-methylguanine in adapted Escherichia coli

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Antifolate-induced misincorporation of deoxyuridine monophosphate into DNA: inhibition of high molecular weight DNA synthesis in human lymphoblastoid cells

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Repair deficient human disorders and cancer

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Effects of Radiation on Polynucleotides

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

The effect of 5-bromouracil treatment on diploid yeast cells

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Macromolecular Synthesis and Thymineless Death in Mycoplasma laidlawii B

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Cytogenetic studies in patients treated with trimethoprim—sulfamethoxazole

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Growth of Lactobacillus acidophilus in the Absence of Folic Acid

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Thymidine as a synchronizing agent. I. Nucleic acid and protein formation in synchronous HeLa cultures treated with excess thymidine

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Unequal crossing over in the ribosomal DNA of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Uracil incorporation into nascent DNA of thymine-requiring mutant of Bacillus subtilis 168

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

EFFECTS OF FLUORODEOXYURIDINE ON DNA REPLICATION, CHROMOSOME BREAKAGE, AND REUNION.

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Folate-dependent enzymes in cultured Chinese hamster cells: Folylpolyglutamate synthetase and its absence in mutants auxotrophic for glycine + adenosine + thymidine

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Therapeutic abortions with a folic acid antagonist, 4-aminopteroylglutamic acid (4-amino P.G.A) administered by the oral route

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Nucleic acid metabolism in yeast II. Metabolism of thymidylate during thymidylate excess death

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Characterization of a guanine-sensitive mutant defective in adenylo-succinate synthetase activity

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Gene amplification in methotrexate-resistant mouse cells. I. DNA rearrangement accompanies dihydrofolate reductase gene amplification in a T-cell lymphoma

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Gene amplification in methotrexate-resistant mouse cells. III. Interrelationships between chromosome changes and DNA sequence amplification or loss

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Characterization of a cell culture model for the study of adenosine deaminase- and purine nucleoside phosphorylase-deficient immunologic disease

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Isolation and characterization of purine-nucleoside phosphorylase-deficient T-lymphoma cells and secondary mutants with altered ribonucleotide reductase: Genetic model for immunodeficiency disease

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Deoxyadenosine metabolism and cytotoxicity in cultured mouse T lymphoma cells: a model for immunodeficiency disease

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Cytogenetic Evaluation of Methotrexate-Treated Psoriatic Patients

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Thymineless death in Bacillus megaterium.

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Attempted abortion with aminopterin (4-amino-pteroylglutamic acid); malformations of the child

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Elevated spontaneous mutation rate in Bloom syndrome fibroblasts

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Apparent mutagenic effect of thymine deficiency for a thymine-requiring strain of Escherichia coli.

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Mutator phenotypes in mammalian cell mutants with distinct biochemical defects and abnormal deoxyribonucleoside triphosphate pools

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Mutagenesis during in vitro DNA synthesis

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Induction of cytoplasmic respiratory deficient mutants in yeast by the folic acid analogue, methotrexate. I. Studies on the mechanism of petite induction.

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

A specific increase in chloroplast gene mutations following growth of Chlamydomonas in 5-fluorodeoxyuridine

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Deoxyriboside Control and Synchronization of Mitosis

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Chromosome aberrations induced by thymidine

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Thymine starvation by inhibition of uptake and synthesis of thymine-compounds in Tetrahymena

1 reference

https://api.crossref.org/works/10.1002%2FEM.2860040609

7 January 2021

Identifiers

DOI

10.1002/EM.2860040609

1 reference

18 September 2017

1 reference