Human ROBO1 is cleaved by metalloproteinases and gamma-secretase and migrates to the nucleus in cancer cells (Q43062776)

13 November 2017

title

Human ROBO1 is cleaved by metalloproteinases and gamma-secretase and migrates to the nucleus in cancer cells (English)

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13 November 2017

8

Hiroyuki Aburatani

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13 November 2017

Motoaki Seki

1

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13 November 2017

Akira Watanabe

2

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13 November 2017

Satoshi Enomoto

3

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13 November 2017

Takeshi Kawamura

4

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13 November 2017

Hirotaka Ito

5

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13 November 2017

Tatsuhiko Kodama

6

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13 November 2017

Takao Hamakubo

7

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13 November 2017

language of work or name

English

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publication date

13 May 2010

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13 November 2017

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13 November 2017

volume

584

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13 November 2017

issue

13

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13 November 2017

page(s)

2909-2915

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Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors

13 November 2017

cites work

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https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Activation of the repulsive receptor Roundabout inhibits N-cadherin-mediated cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Cables links Robo-bound Abl kinase to N-cadherin-bound beta-catenin to mediate Slit-induced modulation of adhesion and transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Chimeric axon guidance receptors: the cytoplasmic domains of slit and netrin receptors specify attraction versus repulsion

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Axonal growth regulation of fetal and embryonic stem cell-derived dopaminergic neurons by Netrin-1 and Slits

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Inadequate lung development and bronchial hyperplasia in mice with a targeted deletion in the Dutt1/Robo1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Targeted disruption of the 3p12 gene, Dutt1/Robo1, predisposes mice to lung adenocarcinomas and lymphomas with methylation of the gene promoter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

The neuronal repellent Slit inhibits leukocyte chemotaxis induced by chemotactic factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Human homolog of NOTUM, overexpressed in hepatocellular carcinoma, is regulated transcriptionally by beta-catenin/TCF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

The ADAMs family of metalloproteases: multidomain proteins with multiple functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Intramembrane proteolysis by presenilins

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Repulsive axon guidance: Abelson and Enabled play opposing roles downstream of the roundabout receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

L1 is sequentially processed by two differently activated metalloproteases and presenilin/gamma-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Mechanism and biological significance of CD44 cleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Got RIP? Presenilin-dependent intramembrane proteolysis in growth factor receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

CD74 is a member of the regulated intramembrane proteolysis-processed protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

Gamma-secretase-mediated proteolysis in cell-surface-receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2010.05.009

10.1016/J.FEBSLET.2010.05.009

21 January 2018

Identifiers

DOI

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13 November 2017

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