cytochrome P450 family 2 subfamily A member 6 (Q5014953)

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mammalian protein found in Homo sapiens

CYP2A6
cytochrome P450 IIA3
flavoprotein-linked monooxygenase
1,4-cineole 2-exo-monooxygenase
cytochrome P450(I)
cytochrome P450 2A6
xenobiotic monooxygenase
CYPIIA6
cytochrome P450, family 2, subfamily A, polypeptide 6
coumarin 7-hydroxylase
cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6
Cytochrome P-450 CYP2A6

Language	Label	Description	Also known as
English	cytochrome P450 family 2 subfamily A member 6	mammalian protein found in Homo sapiens	CYP2A6 cytochrome P450 IIA3 flavoprotein-linked monooxygenase 1,4-cineole 2-exo-monooxygenase cytochrome P450(I) cytochrome P450 2A6 xenobiotic monooxygenase CYPIIA6 cytochrome P450, family 2, subfamily A, polypeptide 6 coumarin 7-hydroxylase cytochrome P450, subfamily IIA (phenobarbital-inducible), polypeptide 6 Cytochrome P-450 CYP2A6

Statements

1 reference

13 November 2019

UniProt protein ID

cytochrome P450 superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P11509

cytochrome P450, E-class, group I, CYP2A-like

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P11509

cytochrome P450, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

iron ion binding

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

arachidonic acid epoxygenase activity

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

determination method or standard

1 reference

27 March 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11509&geneProductId=UniProtKB:P11509

determination method or standard

metal ion binding

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

monooxygenase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

determination method or standard

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

determination method or standard

1 reference

8 April 2019

Interactions of mammalian cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b(5) enzymes

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

oxidoreductase activity

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

coumarin 7-hydroxylase activity

determination method or standard

4 references

10 September 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11509&geneProductId=UniProtKB:P11509

determination method or standard

10 September 2018

Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11509&geneProductId=UniProtKB:P11509

determination method or standard

10 September 2018

Comprehensive in vitro analysis of voriconazole inhibition of eight cytochrome P450 (CYP) enzymes: major effect on CYPs 2B6, 2C9, 2C19, and 3A

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11509&geneProductId=UniProtKB:P11509

determination method or standard

10 September 2018

Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11509&geneProductId=UniProtKB:P11509

determination method or standard

steroid hydroxylase activity

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

determination method or standard

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

determination method or standard

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

8 April 2019

Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

coumarin 7-hydroxylase activity

determination method or standard

3 references

8 April 2019

Structures of human microsomal cytochrome P450 2A6 complexed with coumarin and methoxsalen

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

8 April 2019

Comprehensive in vitro analysis of voriconazole inhibition of eight cytochrome P450 (CYP) enzymes: major effect on CYPs 2B6, 2C9, 2C19, and 3A

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

8 April 2019

Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

organelle membrane

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

intracellular membrane-bounded organelle

determination method or standard

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P11509&geneProductId=UniProtKB:P11509

determination method or standard

endoplasmic reticulum

determination method or standard

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

cytoplasmic microtubule

determination method or standard

1 reference

8 April 2019

MTR120/KIAA1383, a novel microtubule-associated protein, promotes microtubule stability and ensures cytokinesis

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

biological process

steroid metabolic process

determination method or standard

1 reference

8 April 2019

Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

epoxygenase P450 pathway

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

coumarin catabolic process

determination method or standard

1 reference

8 April 2019

Comprehensive in vitro analysis of voriconazole inhibition of eight cytochrome P450 (CYP) enzymes: major effect on CYPs 2B6, 2C9, 2C19, and 3A

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

organic acid metabolic process

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

xenobiotic metabolic process

determination method or standard

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

coumarin metabolic process

determination method or standard

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

8 April 2019

Hepatic cytochrome P450 enzyme alterations in humans with progressive stages of nonalcoholic fatty liver disease

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P11509

determination method or standard

http://purl.uniprot.org/uniprot/P11509

1 reference

Identifiers.org

cytochrome P450, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P11509

Identifiers

MeSH descriptor ID

subject named as

Cytochrome P-450 CYP2A6

0 references

D08.244.453.491.250

0 references

D08.811.682.690.708.170.450.250

0 references

D12.776.422.220.453.491.250

0 references

RefSeq protein ID

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000301141

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000301141

ENSP00000472905

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000472905

PDB structure ID

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

UniProt protein ID

5 August 2016

language of work or name

1 reference

based on heuristic

inferred by common MeSH mappings on source and on Wikidata

25 May 2023

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

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