Doublecortin domain containing 2 (Q5204485)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UHG0

Doublecortin domain-containing protein 2

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q9UHG0

Doublecortin domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

1 reference

13 November 2019

3 references

8 April 2019

DCDC2 mutations cause a renal-hepatic ciliopathy by disrupting Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

8 April 2019

A proteome-scale map of the human interactome network

GOA

curator

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

8 April 2019

Increased expression of the dyslexia candidate gene DCDC2 affects length and signaling of primary cilia in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

kinesin binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

cell component

cytoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

3 references

8 April 2019

8 April 2019

DCDC2 Mutations Cause Neonatal Sclerosing Cholangitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

8 April 2019

Increased expression of the dyslexia candidate gene DCDC2 affects length and signaling of primary cilia in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

cell projection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

1 reference

8 April 2019

kinocilium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHG0&geneProductId=UniProtKB:Q9UHG0

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHG0&geneProductId=UniProtKB:Q9UHG0

24 April 2018

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHG0&geneProductId=UniProtKB:Q9UHG0

cytosol

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

1 reference

8 April 2019

cilium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHG0&geneProductId=UniProtKB:Q9UHG0

6 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHG0&geneProductId=UniProtKB:Q9UHG0

24 April 2018

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHG0&geneProductId=UniProtKB:Q9UHG0

24 April 2018

A missense mutation in DCDC2 causes human recessive deafness DFNB66, likely by interfering with sensory hair cell and supporting cell cilia length regulation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHG0&geneProductId=UniProtKB:Q9UHG0

24 April 2018

DCDC2 Mutations Cause Neonatal Sclerosing Cholangitis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHG0&geneProductId=UniProtKB:Q9UHG0

24 April 2018

Increased expression of the dyslexia candidate gene DCDC2 affects length and signaling of primary cilia in neurons

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHG0&geneProductId=UniProtKB:Q9UHG0

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

1 reference

8 April 2019

microtubule organizing center

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHG0&geneProductId=UniProtKB:Q9UHG0

1 reference

24 April 2018

microtubule cytoskeleton

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

1 reference

8 April 2019

mitotic spindle

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

1 reference

8 April 2019

microtubule

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

cilium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

8 April 2019

A missense mutation in DCDC2 causes human recessive deafness DFNB66, likely by interfering with sensory hair cell and supporting cell cilia length regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

8 April 2019

DCDC2 Mutations Cause Neonatal Sclerosing Cholangitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

8 April 2019

Increased expression of the dyslexia candidate gene DCDC2 affects length and signaling of primary cilia in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

axoneme

DCDC2 mutations cause a renal-hepatic ciliopathy by disrupting Wnt signaling

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

8 April 2019

DCDC2 Mutations Cause Neonatal Sclerosing Cholangitis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

cortical actin cytoskeleton

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

kinocilium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

cellular defense response

biological process

TAS

1 reference

8 April 2019

A new antigen recognized by cytolytic T lymphocytes on a human kidney tumor results from reverse strand transcription

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

intracellular signal transduction

TAS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

1 reference

8 April 2019

neuron migration

DCDC2 is associated with reading disability and modulates neuronal development in the brain

3 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHG0&geneProductId=UniProtKB:Q9UHG0

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHG0&geneProductId=UniProtKB:Q9UHG0

24 April 2018

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHG0&geneProductId=UniProtKB:Q9UHG0

cell projection organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

1 reference

8 April 2019

positive regulation of smoothened signaling pathway

1 reference

8 April 2019

Increased expression of the dyslexia candidate gene DCDC2 affects length and signaling of primary cilia in neurons

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

nervous system development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

1 reference

8 April 2019

cilium assembly

1 reference

24 April 2018

DCDC2 Mutations Cause Neonatal Sclerosing Cholangitis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q9UHG0&geneProductId=UniProtKB:Q9UHG0

neuron migration

DCDC2 is associated with reading disability and modulates neuronal development in the brain

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

8 April 2019

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

dendrite morphogenesis

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

regulation of cilium assembly

A missense mutation in DCDC2 causes human recessive deafness DFNB66, likely by interfering with sensory hair cell and supporting cell cilia length regulation

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

8 April 2019

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9UHG0

1 reference

InterPro Release 71.0