estrogen receptor 1 (Q5401858)

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mammalian protein found in Homo sapiens
  • estrogen receptor
  • E2 receptor alpha
  • ESR1
  • estrogen nuclear receptor alpha
  • nuclear receptor subfamily 3 group A member 1
  • ER-alpha
  • oestrogen receptor alpha
  • estrogen receptor alpha E1-N2-E2-1-2
  • estrogen receptor alpha E1-E2-1-2
  • estradiol receptor
  • Estrogen Receptor alpha
edit
Language Label Description Also known as
English
estrogen receptor 1
mammalian protein found in Homo sapiens
  • estrogen receptor
  • E2 receptor alpha
  • ESR1
  • estrogen nuclear receptor alpha
  • nuclear receptor subfamily 3 group A member 1
  • ER-alpha
  • oestrogen receptor alpha
  • estrogen receptor alpha E1-N2-E2-1-2
  • estrogen receptor alpha E1-E2-1-2
  • estradiol receptor
  • Estrogen Receptor alpha

Statements

molecular function
protein binding
determination method or standard
IPI
85 references
retrieved
8 April 2019
stated in
ERRF is essential for Estrogen-Estrogen Receptor alpha signaling pathway in ER positive breast cancer cells
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Dosage-sensitive sex reversal adrenal hypoplasia congenita critical region on the X chromosome, gene 1 (DAX1) (NR0B1) and small heterodimer partner (SHP) (NR0B2) form homodimers individually, as well as DAX1-SHP heterodimers
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Functional regulation of oestrogen receptor pathway by the dynein light chain 1.
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Interaction of the tumor metastasis suppressor nonmetastatic protein 23 homologue H1 and estrogen receptor alpha alters estrogen-responsive gene expression
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
The human homologue of the yeast DNA repair and TFIIH regulator MMS19 is an AF-1-specific coactivator of estrogen receptor
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Repression of estrogen receptor beta function by putative tumor suppressor DBC1
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Cooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancer
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
The TRAP220 component of a thyroid hormone receptor- associated protein (TRAP) coactivator complex interacts directly with nuclear receptors in a ligand-dependent fashion
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Functional interaction of DYX1C1 with estrogen receptors suggests involvement of hormonal pathways in dyslexia
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II)
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Mammalian MST2 kinase and human Salvador activate and reduce estrogen receptor alpha in the absence of ligand
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Suppression of estrogen receptor-mediated transcription and cell growth by interaction with TR2 orphan receptor
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Human ADA3 regulates RARalpha transcriptional activity through direct contact between LxxLL motifs and the receptor coactivator pocket
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alpha
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Modification of ASC1 by UFM1 is crucial for ERα transactivation and breast cancer development
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
MS-KIF18A, a kinesin, is associated with estrogen receptor
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Modulation of ER alpha transcriptional activity by the orphan nuclear receptor ERR beta and evidence for differential effects of long- and short-form splice variants.
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
WW domain binding protein-2, an E6-associated protein interacting protein, acts as a coactivator of estrogen and progesterone receptors
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
ERAP75 functions as a coactivator to enhance estrogen receptor alpha transactivation in prostate stromal cells
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
H3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic gene BCL2 determines ERα ligand dependency
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
TRIM24 links a non-canonical histone signature to breast cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Variant estrogen receptor-c-Src molecular interdependence and c-Src structural requirements for endothelial NO synthase activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Characterization of Brx, a novel Dbl family member that modulates estrogen receptor action
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Suppression of estrogen receptor transcriptional activity by connective tissue growth factor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Functional Synergy between the Transcription Factor Sp1 and the Estrogen Receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Proteomic identification of Profilin1 as a corepressor of estrogen receptor alpha in MCF7 breast cancer cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
RAC3 is a pro-migratory co-activator of ERα
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
SAFB2, a new scaffold attachment factor homolog and estrogen receptor corepressor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
The catalytic subunit of the proteasome is engaged in the entire process of estrogen receptor-regulated transcription
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
CUE domain containing 2 regulates degradation of progesterone receptor by ubiquitin-proteasome
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
NF-kappaB and estrogen receptor alpha interactions: Differential function in estrogen receptor-negative and -positive hormone-independent breast cancer cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERalpha, is required for coregulator occupancy and chromatin modification
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification of the MLL2 complex as a coactivator for estrogen receptor alpha
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Modulator recognition factor 1, an AT-rich interaction domain family member, is a novel corepressor for estrogen receptor alpha
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Interaction between transcription factor, basal transcription factor 3, and the NH2-terminal domain of human estrogen receptor alpha
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Repression of the Interleukin-6 Promoter by Estrogen Receptor Is Mediated by NF-κB and C/EBPβ
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Progesterone receptor modulates ERα action in breast cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Negative regulation of ERα by a novel protein CAC1 through association with histone demethylase LSD1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
GAS, a new glutamate-rich protein, interacts differentially with SRCs and is involved in oestrogen receptor function
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Forkhead homologue in rhabdomyosarcoma functions as a bifunctional nuclear receptor-interacting protein with both coactivator and corepressor functions
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
An inherent role of microtubule network in the action of nuclear receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Characterization of the physical interaction between estrogen receptor alpha and JUN proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Synergism between ERalpha transactivation function 1 (AF-1) and AF-2 mediated by steroid receptor coactivator protein-1: requirement for the AF-1 alpha-helical core and for a direct interaction between the N- and C-terminal domains
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Synergy between estrogen receptor alpha activation functions AF1 and AF2 mediated by transcription intermediary factor TIF2.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Keratin 18 attenuates estrogen receptor alpha-mediated signaling by sequestering LRP16 in cytoplasm
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
MDM2 enhances the function of estrogen receptor alpha in human breast cancer cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Epidermal growth factor directs sex-specific steroid signaling through Src activation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Characterization of the interactions of estrogen receptor and MNAR in the activation of cSrc
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Protein phosphatase 5 is a negative regulator of estrogen receptor-mediated transcription
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Estrogenically regulated LRP16 interacts with estrogen receptor alpha and enhances the receptor's transcriptional activity
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
UXT Is a LOX-PP Interacting Protein That Modulates Estrogen Receptor Alpha Activity in Breast Cancer Cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Activation of rapid oestrogen signalling in aggressive human breast cancers
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Estrogen and Estrogen Receptor-α-Mediated Transrepression of Bile Salt Export Pump
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
T:G mismatch-specific thymine-DNA glycosylase (TDG) as a coregulator of transcription interacts with SRC1 family members through a novel tyrosine repeat motif
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Inhibition of vascular endothelial growth factor expression in HEC1A endometrial cancer cells through interactions of estrogen receptor alpha and Sp3 proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
A new family of nuclear receptor coregulators that integrate nuclear receptor signaling through CREB-binding protein
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Systematic identification of molecular links between core and candidate genes in breast cancer
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Kinome screening for regulators of the estrogen receptor identifies LMTK3 as a new therapeutic target in breast cancer.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
An alternative splicing variant of the selenoprotein thioredoxin reductase is a modulator of estrogen signaling
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Additional sex comb-like 1 (ASXL1), in cooperation with SRC-1, acts as a ligand-dependent coactivator for retinoic acid receptor
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Two domains of the progesterone receptor interact with the estrogen receptor and are required for progesterone activation of the c-Src/Erk pathway in mammalian cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Identification and characterization of novel spliced variants of PRMT2 in breast carcinoma
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
A large set of estrogen receptor β‐interacting proteins identified by tandem affinity purification in hormone‐responsive human breast cancer cell nuclei
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
PKA-induced resistance to tamoxifen is associated with an altered orientation of ERalpha towards co-activator SRC-1
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
ZNF366 is an estrogen receptor corepressor that acts through CtBP and histone deacetylases
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Structural determinants of the BRCA1 : estrogen receptor interaction
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
A negative coregulator for the human ER
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
JMJD6 regulates ERα methylation on arginine
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Estrogen receptor alpha mediates progestin-induced mammary tumor growth by interacting with progesterone receptors at the cyclin D1/MYC promoters
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
An estrogen receptor-selective coregulator that potentiates the effectiveness of antiestrogens and represses the activity of estrogens
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
Metabolism, cytoskeleton and cellular signalling in the grip of protein Nepsilon - and O-acetylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
ERbeta Binds N-CoR in the Presence of Estrogens via an LXXLL-like Motif in the N-CoR C-terminus
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
retrieved
8 April 2019
stated in
The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IPI
cell component
nucleus
determination method or standard
IDA
IEA
8 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IEA
retrieved
8 April 2019
stated in
Estrogen induces expression of BCAS3, a novel estrogen receptor-alpha coactivator, through proline-, glutamic acid-, and leucine-rich protein-1 (PELP1)
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IDA
retrieved
8 April 2019
stated in
Repression of estrogen receptor beta function by putative tumor suppressor DBC1
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IDA
retrieved
8 April 2019
stated in
Cooperative interaction between retinoic acid receptor-alpha and estrogen receptor in breast cancer
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IDA
retrieved
8 April 2019
stated in
Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alpha
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IDA
retrieved
8 April 2019
stated in
Oestrogen receptor facilitates the formation of preinitiation complex assembly: involvement of the general transcription factor TFIIB
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IDA
biological process
positive regulation of transcription by RNA polymerase II
determination method or standard
IDA
IEA
6 references
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IEA
retrieved
8 April 2019
stated in
Estrogen receptor (ER)-mediated transcriptional regulation of the human corticotropin-releasing hormone-binding protein promoter: differential effects of ERalpha and ERbeta
GOA
curator
UniProt
UniProt protein ID
P03372
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IDA
retrieved
8 April 2019
stated in
ERAP75 functions as a coactivator to enhance estrogen receptor alpha transactivation in prostate stromal cells
GOA
curator
Parkinsons Disease Gene Ontology Initiative
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IDA
retrieved
8 April 2019
stated in
The affinity and activity of the multiple hormone response element in the proximal promoter of the human oxytocin gene
GOA
curator
Norwegian University of Science and Technology, Systems Biology team
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IDA
retrieved
8 April 2019
stated in
Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily
GOA
curator
Mouse Genome Informatics
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IDA
retrieved
8 April 2019
stated in
Functional genomics identifies a mechanism for estrogen activation of the retinoic acid receptor alpha1 gene in breast cancer cells
GOA
curator
British Heart Foundation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P03372
determination method or standard
IDA
physically interacts with

Identifiers

MeSH descriptor ID
D047628
subject named as
Estrogen Receptor alpha
0 references
RefSeq protein ID
PDB structure ID
 
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