Pages that link to "Q34293264"

The following pages link to Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/beta and for signal transduction. (Q34293264):

Displaying 50 items.

• Mutant U5A cells are complemented by an interferon-alpha beta receptor subunit generated by alternative processing of a new member of a cytokine receptor gene cluster (Q24313936) (← links)
• The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals (Q24323741) (← links)
• Cloning and Expression of a Long Form of the β Subunit of the Interferon αβ Receptor That Is Required for Signaling (Q24337125) (← links)
• Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway (Q24531184) (← links)
• Kinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral state (Q24562872) (← links)
• The amino-terminal region of Tyk2 sustains the level of interferon alpha receptor 1, a component of the interferon alpha/beta receptor (Q24649983) (← links)
• Modulation of Activation-Loop Phosphorylation by JAK Inhibitors Is Binding Mode Dependent (Q27681086) (← links)
• The crystal structure of human interferon beta at 2.2-A resolution (Q27746372) (← links)
• Signaling through the JAK/STAT pathway, recent advances and future challenges (Q28201804) (← links)
• The Type I Interferon Receptor Mediates Tyrosine Phosphorylation of the CrkL Adaptor Protein (Q28255013) (← links)
• Human TYK2 deficiency: Mycobacterial and viral infections without hyper-IgE syndrome (Q28266613) (← links)
• Characterization of beta-R1, a gene that is selectively induced by interferon beta (IFN-beta) compared with IFN-alpha (Q28289207) (← links)
• Janus kinases in interleukin-2-mediated signaling: JAK1 and JAK3 are differentially regulated by tyrosine phosphorylation (Q28637960) (← links)
• Catalytically active TYK2 is essential for interferon-beta-mediated phosphorylation of STAT3 and interferon-alpha receptor-1 (IFNAR-1) but not for activation of phosphoinositol 3-kinase (Q28646398) (← links)
• Interferon-alpha-dependent activation of Tyk2 requires phosphorylation of positive regulatory tyrosines by another kinase (Q28646526) (← links)
• TYK2 kinase activity is required for functional type I interferon responses in vivo (Q28728338) (← links)
• A dual role for the kinase-like domain of the tyrosine kinase Tyk2 in interferon-alpha signaling (Q31794325) (← links)
• Advances in cytokine signaling: the role of Jaks and STATs (Q33636594) (← links)
• Janus kinases and their role in growth and disease (Q33664276) (← links)
• Cytokines and STAT signaling (Q33784715) (← links)
• The Jak-STAT pathway (Q33899139) (← links)
• Complex effects of naturally occurring mutations in the JAK3 pseudokinase domain: evidence for interactions between the kinase and pseudokinase domains (Q33961743) (← links)
• Homodimerization and intermolecular tyrosine phosphorylation of the Tyk‐2 tyrosine kinase (Q34058092) (← links)
• Specific contribution of Tyk2 JH regions to the binding and the expression of the interferon alpha/beta receptor component IFNAR1. (Q34067425) (← links)
• Janus kinases: components of multiple signaling pathways (Q34103659) (← links)
• Jak3-independent trafficking of the common gamma chain receptor subunit: chaperone function of Jaks revisited (Q34181570) (← links)
• A single nucleotide polymorphism in Tyk2 controls susceptibility to experimental allergic encephalomyelitis (Q34433877) (← links)
• The tyrosine kinase Tyk2 controls IFNAR1 cell surface expression. (Q34463632) (← links)
• The JAK/STAT pathway and Drosophila development (Q34464680) (← links)
• Jak2-Stat5 interactions analyzed in yeast (Q34467000) (← links)
• Regulation of the Jak2 tyrosine kinase by its pseudokinase domain (Q34508384) (← links)
• The pseudokinase domain is required for suppression of basal activity of Jak2 and Jak3 tyrosine kinases and for cytokine-inducible activation of signal transduction (Q34527668) (← links)
• Jaks, STATs, Cytokines, and Sepsis (Q34987949) (← links)
• JAK/STAT, Raf/MEK/ERK, PI3K/Akt and BCR-ABL in cell cycle progression and leukemogenesis (Q35635353) (← links)
• Janus kinase 3: the controller and the controlled (Q35770946) (← links)
• Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2). (Q36283829) (← links)
• Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways (Q36566064) (← links)
• Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia. (Q37109227) (← links)
• Ligand-independent interaction of the type I interferon receptor complex is necessary to observe its biological activity (Q37164886) (← links)
• Tyrosine kinase 2 is not limiting human antiviral type III interferon responses (Q38733510) (← links)
• Phosphorylation of STAT2 on serine-734 negatively regulates the IFN-α-induced antiviral response (Q38734547) (← links)
• The Janus Kinase (JAK) FERM and SH2 Domains: Bringing Specificity to JAK-Receptor Interactions (Q39274304) (← links)
• Autoinhibition of Jak2 tyrosine kinase is dependent on specific regions in its pseudokinase domain (Q39745564) (← links)
• Regulation of Jak2 function by phosphorylation of Tyr317 and Tyr637 during cytokine signaling (Q39861252) (← links)
• The Stat3-activating Tyk2 V678F mutant does not up-regulate signaling through the type I interferon receptor but confers ligand hypersensitivity to a homodimeric receptor (Q39985388) (← links)
• Inhibition of alpha interferon but not gamma interferon signal transduction by phorbol esters is mediated by a tyrosine phosphatase (Q40018479) (← links)
• JAK kinases promote invasiveness in VHL-mediated renal cell carcinoma by a suppressor of cytokine signaling-regulated, HIF-independent mechanism (Q40075798) (← links)
• JAK1 and Tyk2 activation by the homologous polycythemia vera JAK2 V617F mutation: cross-talk with IGF1 receptor. (Q40359732) (← links)
• Vanadate facilitates interferon alpha-mediated apoptosis that is dependent on the Jak/Stat pathway (Q40817313) (← links)
• Tyrosine phosphorylation of Jak2 in the JH2 domain inhibits cytokine signaling (Q40886434) (← links)