var wb = new XLWorkbook();
var ws = wb.Worksheets.Add("Hyperlinks");
wb.Worksheets.Add("Second Sheet");

Int32 ro = 0;

// You can create a link with pretty much anything you can put on a
// browser: http, ftp, mailto, gopher, news, nntp, etc.

ws.Cell(++ro, 1).Value = "Link to a web page, no tooltip - Yahoo!";
ws.Cell(ro, 1).Hyperlink = new XLHyperlink(@"http://www.yahoo.com");

ws.Cell(++ro, 1).Value = "Link to a web page, with a tooltip - Yahoo!";
ws.Cell(ro, 1).Hyperlink = new XLHyperlink(@"http://www.yahoo.com", "Click to go to Yahoo!");

ws.Cell(++ro, 1).Value = "Link to a file - same folder";
ws.Cell(ro, 1).Hyperlink = new XLHyperlink("Test.xlsx");

ws.Cell(++ro, 1).Value = "Link to a file - relative address";
ws.Cell(ro, 1).Hyperlink = new XLHyperlink(@"../Test.xlsx");

ws.Cell(++ro, 1).Value = "Link to an address in this worksheet";
ws.Cell(ro, 1).Hyperlink = new XLHyperlink("B1");

ws.Cell(++ro, 1).Value = "Link to an address in another worksheet";
ws.Cell(ro, 1).Hyperlink = new XLHyperlink("'Second Sheet'!A1");

// You can also set the properties of a hyperlink directly:

ws.Cell(++ro, 1).Value = "Link to a range in this worksheet";
ws.Cell(ro, 1).Hyperlink.InternalAddress = "B1:C2";
ws.Cell(ro, 1).Hyperlink.Tooltip = "SquareBox";

ws.Cell(++ro, 1).Value = "Link to an email message";
ws.Cell(ro, 1).Hyperlink.ExternalAddress = new Uri(@"mailto:SantaClaus@NorthPole.com?subject=Presents");

// Deleting a hyperlink
ws.Cell(++ro, 1).Value = "This is no longer a link";
ws.Cell(ro, 1).Hyperlink.InternalAddress = "A1";
ws.Cell(ro, 1).Hyperlink.Delete();

// Setting a hyperlink preserves previous formatting:
ws.Cell(++ro, 1).Value = "Odd looking link";
ws.Cell(ro, 1).Style.Font.FontColor = XLColor.Red;
ws.Cell(ro, 1).Style.Font.Underline = XLFontUnderlineValues.Double;
ws.Cell(ro, 1).Hyperlink = new XLHyperlink(ws.Range("B1:C2"));

// List all hyperlinks in a worksheet:
var hyperlinksInWorksheet = ws.Hyperlinks;

// List all hyperlinks in a range:
var hyperlinksInRange = ws.Range("A1:A3").Hyperlinks;

ws.Columns().AdjustToContents();

wb.SaveAs("Hyperlinks.xlsx");