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SEPT11

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SEPT11
Identifikatori
AliasiSEPTIN11
Vanjski ID-jeviOMIM: 612887 MGI: 1277214 HomoloGene: 56800 GeneCards: SEPTIN11
Lokacija gena (čovjek)
Hromosom 4 (čovjek)
Hrom.Hromosom 4 (čovjek)[1]
Hromosom 4 (čovjek)
Genomska lokacija za SEPT11
Genomska lokacija za SEPT11
Bend4q21.1Početak76,949,751 bp[1]
Kraj77,040,384 bp[1]
Lokacija gena (miš)
Hromosom 5 (miš)
Hrom.Hromosom 5 (miš)[2]
Hromosom 5 (miš)
Genomska lokacija za SEPT11
Genomska lokacija za SEPT11
Bend5 E2|5 47.29 cMPočetak93,241,296 bp[2]
Kraj93,324,306 bp[2]
Ontologija gena
Molekularna funkcija nucleotide binding
GTP binding
GO:0001948, GO:0016582 vezivanje za proteine
GO:0006184 GTPase activity
GO:0032947 molecular adaptor activity
Ćelijska komponenta citoplazma
Akson
međućelijske veze
dendritična kičma
projekcija ćelije
sinapsa
citoskelet
stress fiber
postsynapse
glutamatergic synapse
GABA-ergic synapse
postsynaptic specialization of symmetric synapse
septin ring
microtubule cytoskeleton
septin complex
septin filament array
Biološki proces ćelijski ciklus
protein heterooligomerization
Ćelijska dioba
GO:1904739 regulation of synapse organization
mitotic cytokinesis
septin ring assembly
cilium assembly
cytoskeleton-dependent cytokinesis
Izvori:Amigo / QuickGO
Ortolozi
VrsteČovjekMiš
Entrez
Ensembl
UniProt
RefSeq (mRNK)

NM_001306147
NM_018243

NM_001009818
NM_001310669
NM_001310671
NM_001347377

RefSeq (bjelančevina)

NP_001293076
NP_060713

NP_001009818
NP_001297598
NP_001297600
NP_001334306

Lokacija (UCSC)Chr 4: 76.95 – 77.04 MbChr 5: 93.24 – 93.32 Mb
PubMed pretraga[3][4]
Wikipodaci
Pogledaj/uredi – čovjekPogledaj/uredi – miš

Septin-11 jest protein koji je kod ljudi kodiran genom SEPT11 sa hromosoma 4.[5][6][7]

Aminokiselinska sekvenca

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Dužina polipeptidnog lanca je 429 aminokiselina, а molekulska težina 49.398 Da.[8]

1020304050
MAVAVGRPSNEELRNLSLSGHVGFDSLPDQLVNKSTSQGFCFNILCVGET
GIGKSTLMDTLFNTKFESDPATHNEPGVRLKARSYELQESNVRLKLTIVD
TVGFGDQINKDDSYKPIVEYIDAQFEAYLQEELKIKRSLFNYHDTRIHAC
LYFIAPTGHSLKSLDLVTMKKLDSKVNIIPIIAKADTIAKNELHKFKSKI
MSELVSNGVQIYQFPTDEETVAEINATMSVHLPFAVVGSTEEVKIGNKMA
KARQYPWGVVQVENENHCDFVKLREMLIRVNMEDLREQTHTRHYELYRRC
KLEEMGFKDTDPDSKPFSLQETYEAKRNEFLGELQKKEEEMRQMFVMRVK
EKEAELKEAEKELHEKFDLLKRTHQEEKKKVEDKKKELEEEVNNFQKKKA
AAQLLQSQAQQSGAQQTKKDKDKKNASFT

Reference

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000138758 - Ensembl, maj 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000058013 - Ensembl, maj 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Kojima K, Sakai I, Hasegawa A, Niiya H, Azuma T, Matsuo Y, Fujii N, Tanimoto M, Fujita S (maj 2004). "FLJ10849, a septin family gene, fuses MLL in a novel leukemia cell line CNLBC1 derived from chronic neutrophilic leukemia in transformation with t(4;11)(q21;q23)". Leukemia. 18 (5): 998–1005. doi:10.1038/sj.leu.2403334. PMID 14999297.
  6. ^ Kim DS, Hubbard SL, Peraud A, Salhia B, Sakai K, Rutka JT (maj 2004). "Analysis of mammalian septin expression in human malignant brain tumors". Neoplasia. 6 (2): 168–78. doi:10.1593/neo.03310. PMC 1502092. PMID 15140406.
  7. ^ "Entrez Gene: SEPT11 septin 11".
  8. ^ "UniProt, Q9NVA2" (jezik: engleski). Pristupljeno 30. 10. 2021.

Dopunska literatura

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