Camille H Raynes-Greenow

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Jean-Christophe Plantin

London School of Economics and Political Science

David Seamon

Kansas State University

Theodore Arabatzis

National & Kapodistrian University of Athens

Katherine Mason

Miami University

Catherine Mills

Monash University

Tomasz Komendzinski

Nicolaus Copernicus University

Deborah Lupton

The University of New South Wales

Sergio Rego

Fundação Oswaldo Cruz

Anna C. Zielinska

Université de Lorraine

Ngan Dong

Ho Chi Minh City University of technology

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Papers by Camille H Raynes-Greenow

Poor sleep during the periconceptional period increases risk for neural tube defects in offspring

Birth defects research. Part A, Clinical and molecular teratology, Jan 16, 2015

Poor sleep has been studied in relation to various diseases. Few studies have investigated the ef... more Poor sleep has been studied in relation to various diseases. Few studies have investigated the effect of poor sleep on birth defects. We examined the association of maternal poor sleep during periconceptional period and the risk of neural tube defects (NTDs) in offspring based on a large case-control study in northern China. The subjects included 629 NTD cases and 858 normal controls investigated between 2002 and 2007. Maternal sleep status was collected by health workers within first week after delivery. Logistic regression was used to estimate the odds ratio (OR) and 95% confidence interval (CI) of NTDs in association with poor sleep. The proportion of mothers with frequent poor sleep (≥4 days/week on average) was markedly higher in NTDs group (5.9%) than in control group (1.2%). In the multivariate analysis, frequent poor sleep was significantly associated with an increased risk of total NTDs (adjusted OR, 4.1; 95% CI, 1.9-8.8) and spina bifida subtype (adjusted OR, 6.4; 95% CI, ...

Prevalence and Predictors of Iron Deficiency Anemia in Children under Five Years of Age in Pakistan, A Secondary Analysis of National Nutrition Survey Data 2011–2012

PLOS ONE, 2016

Iron deficiency Anemia (IDA) in children is a recognized public health problem that impacts adver... more Iron deficiency Anemia (IDA) in children is a recognized public health problem that impacts adversely on child morbidity, mortality and impairs cognitive development. In Pakistan information on the true prevalence and predictors of IDA is limited. This study sought to investigate IDA in children under five years of age using data from a nationally representative stratified cross-sectional survey. Secondary analysis was performed on the National Nutrition Survey in Pakistan 2011-2012. We used a pre-structured instrument to collect socio demographic and nutritional data on mothers and children. We also collected Anthropometric measurements and blood samples for micronutrient deficiencies. IDA was defined as having both haemoglobin levels of &lt;110 g/L and ferritin levels of &lt; 12 μg/L. Data analysis was performed by applying univariate and multivariate techniques using logistic regression through SPSS. A total of 7138 children aged between 6-59 months were included in the analysis. The prevalence of IDA was 33.2%. In multivariate regression analysis adjusted odds ratios (AOR) were calculated. Age &lt; 24 months (AOR 1.40, 95% CI 1.18-1.55 p &lt;0.05), stunting (AOR 1.42 CI 1.23-1.63 p&lt;0.05), presence of clinical anemia (AOR 5.69 CI 4.93-6.56 p&lt;0.05), having a mother with IDA (AOR 1.72 CI 1.47-2.01 p&lt;0.05) and household food insecurity (AOR 1.20 CI 1.10-1.40 P&lt;0.05) were associated with IDA. Living in a rural area (AOR 0.77 CI 0.65-0.90 p&lt;0.05) and being a female child (AOR 0.87 CI 0.76-0.98 p&lt;0.05) were associated with reduced odds of IDA. The prevalence of IDA amongst Pakistani children represents a moderate burden that disproportionately affects the youngest, growth retarded children, affected children are more likely to have mothers with IDA and live in areas where food security is lacking. National efforts to alleviate the burden of IDA should involve both short term vertical programs such as iron supplementation and long term horizontal programs including wheat flour fortification.

Long-term survival for infants born with orofacial clefts in Western Australia

Birth Defects Research Part A: Clinical and Molecular Teratology, 2015

Only two population-based studies have reported survival beyond 15 years for individuals with oro... more Only two population-based studies have reported survival beyond 15 years for individuals with orofacial clefts (OFC), and only for individuals with isolated OFC. Compared with the general population, long-term survival was similar for individuals with cleft lip only, and lower for individuals with cleft palate only. Results for those born with isolated cleft lip and cleft palate were inconsistent. Using linked population-based health data, including a congenital anomaly register with active surveillance and diagnoses up to 6 years, we compared survival at 1, 5, and 20 years for infants born 1980 to 2010 with, and without OFC. Of the 8112 live born infants in the cohort, 186 died before 20 years; most (81%) died during infancy. Compared with infants without OFC, infants born with all types of isolated OFC ± additional minor anomalies had similar infant survival (around 99%), but we found lower survival for infants with all cleft types and an additional major anomaly (66-84%). From 1 to 5 years, only infants with cleft palate only and an additional major anomaly had lower survival (97%) compared with children without OFC (99.9%). From 5 to 20 years, children with all cleft types, with or without additional major anomalies had similar survival to children without OFC (98-100%). Parents with a child diagnosed with an OFC ± additional minor anomalies only can be reassured that the OFC does not influence survival rates in infancy, or long-term. Infant survival was lower only for children with OFC and additional major anomalies. Birth Defects Research (Part A), 2015. © 2015 Wiley Periodicals, Inc.

Hospitalisations up to adulthood for children born with orofacial clefts

Journal of Paediatrics and Child Health, 2015

The aim of this study was to compare hospital admissions from infancy to adulthood, between child... more The aim of this study was to compare hospital admissions from infancy to adulthood, between children born with orofacial clefts (OFC) and those without OFC. The method used was a cohort study using record-linked administrative datasets. Participants included all children liveborn in Western Australia (WA) between 1980 and 2010 diagnosed with OFC, who were frequency matched by year of birth to randomly selected liveborn children without OFC. We calculated rate ratios (RR) of hospital admission, number and reason of admissions, cumulative length of stay, for each cleft type (cleft lip only (CLO), cleft lip and palate (CL+P), cleft palate only (CPO), no OFC) and by age period (infancy, pre-school, primary and high school ages, and early adulthood). Overall, 1396 children were diagnosed with an OFC and compared with 6566 children without OFC. Individuals born with OFC were up to three times more likely to be admitted to hospital, had more admissions and longer cumulative length of stay in all age periods. Children with OFC were also more likely to be admitted for ear and digestive system conditions (RR up to 30 and six times higher, respectively). Children with CL+P and CPO were more likely to be admitted for respiratory conditions (RR 1.3-2.0) and children with CPO were six times more likely to be admitted for care for other congenital anomalies. Throughout childhood, individuals born with OFC were more likely to be admitted, and had more hospitalisations than those without OFC. Children born with CL+P or CPO had a higher hospitalisation burden than children born with CLO.

Knowledge and decision making for labour pain management of Australian women pregnant with their first baby

Midwifery

Zhang 2013 Invited Commentary the incremental value of customization in defining abnormal fetal growth status

Reference tools based on birth weight percentiles at a given gestational week have long been used... more Reference tools based on birth weight percentiles at a given gestational week have long been used to define fetuses or infants that are small or large for their gestational ages. However, important deficiencies of the birth weight reference are being increasingly recognized. Overwhelming evidence indicates that an ultrasonographybased fetal weight reference should be used to classify fetal and newborn sizes during pregnancy and at birth, respectively. Questions have been raised as to whether further adjustments for race/ethnicity, parity, sex, and maternal height and weight are helpful to improve the accuracy of the classification. In this issue of the Journal, Carberry et al. (Am J Epidemiol. 2013;178(XX):XXXX-XXXX) show that adjustment for race/ethnicity is useful, but that additional fine tuning for other factors (i.e., full customization) in the classification may not further improve the ability to predict infant morbidity, mortality, and other fetal growth indicators. Thus, the theoretical advantage of full customization may have limited incremental value for pediatric outcomes, particularly in term births. Literature on the prediction of short-term maternal outcomes and very long-term outcomes (adult diseases) is too scarce to draw any conclusions. Given that each additional variable being incorporated in the classification scheme increases complexity and costs in practice, the clinical utility of full customization in obstetric practice requires further testing. birth weight; customization; fetal growth; large for gestational age; small for gestational age Abbreviations: LGA, large for gestational age; SGA, small for gestational age.

Camille H Raynes-Greenow

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