Chlorphenoxamine

Chlorphenoxamine
Systematic (IUPAC) name
	{2-[1-(4-chlorophenyl)-1-phenylethoxy]ethyl}dimethylamine
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral, topical
Pharmacokinetic data
Bioavailability	Well absorbed
Metabolism	Likely hepatic
Excretion	Renal
Identifiers
CAS Number	77-38-3 Template:CAS
ATC code	D04AA34 (WHO) R06AA06
PubChem	CID: 6475
DrugBank	DB09007
ChemSpider	6230
UNII	3UVD77BP8R
KEGG	D07198
ChEMBL	CHEMBL2110774
Chemical data
Formula	C18H22ClNO
Molecular mass	303.826 g/mol
	SMILES Clc1ccc(cc1)C(OCCN(C)C)(c2ccccc2)C ;
	InChI InChI=1S/C18H22ClNO/c1-18(21-14-13-20(2)3,15-7-5-4-6-8-15)16-9-11-17(19)12-10-16/h4-12H,13-14H2,1-3H3 ; Key:KKHPNPMTPORSQE-UHFFFAOYSA-N ;
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Chlorphenoxamine (Phenoxene) is an antihistamine and anticholinergic used as an antipruritic^[1] and antiparkinsonian^[2] agent. It is an analog of diphenhydramine.^[3]

References

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↑ H. Arnold, N. Brock, E. Kuhas, and D. Lorenz, Arzneimittel Forsch., 4, 189 (1954).

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v t e Antipruritics (D04)
Antihistamines for topical use	Thonzylamine Mepyramine Thenalidine Tripelennamine Chloropyramine Promethazine Tolpropamine Dimetindene Clemastine Bamipine Isothipendyl Diphenhydramine Chlorphenoxamine
Anesthetics for topical use	Lidocaine Dibucaine Oxybuprocaine Benzocaine Quinisocaine Tetracaine Pramocaine
Others	Corticosteroids (e.g., hydrocortisone) Counterirritants (e.g., mint oil, menthol, camphor) Nalfurafine