GW Pharmaceuticals

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GW Pharmaceuticals PLC
Public Limited Company
Traded as NASDAQ: GWPH
LSE: GWP
Industry Pharmaceutical
Founded 1998
Founder Geoffrey Guy and Brian Whittle
Headquarters Porton Down Science Park, United Kingdom[1]
Key people
 Justin Gover[2]
Products Sativex®
Revenue $33.8 million (2001)[3]
Divisions Biotechnology
Website www.gwpharm.com

GW Pharmaceuticals is a British biopharmaceutical company known for its multiple sclerosis treatment product Sativex, nabiximols (brand name, Sativex). Sativex is the first natural cannabis plant derivative to gain market approval in any country.[4] Another cannabis-based product, Epidiolex, for treatment of epilepsy, underwent phase 3 clinical trials in 2015.[5][6]

History

Background

Doctors Geoffrey Guy and Brian Whittle founded GW Pharmaceuticals in 1998. That year they obtained a cultivation license from the United Kingdom Home Office and the MHRA, allowing GW Pharmaceuticals to cultivate cannabis from seeds and clones to conduct scientific research concerning the medicinal uses of the plant.[7][8]

HortaPharm

In July 1998, GW Pharmaceuticals collaborated with HortaPharm B.V., a cannabis research and development business based in the Netherlands,[9] founded by two expert horticulturists from California,[10] Robert Connell Clarke[11] and David Paul Watson, also known as 'Sam the Skunkman'. [12] HortaPharm grew medicinal strains for the Dutch government.[13][14] [15] [16]

Marketed products

Sativex

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Main article: Nabiximols

Nabiximols (trade name Sativex) is a botanical drug that is a cannabis extract, administered as a mouth spray; it was approved in the UK in 2010 as a treatment for multiple sclerosis (MS) patients to alleviate neuropathic pain, spasticity, overactive bladder, and other symptoms.[17]

Nabiximols is made with two unknown Cannabis strains, and is extracted with ethanol and carbon dioxide.[18][19]

In 2011, GW Pharmaceuticals concluded a partnership with Bayer for the distribution of Sativex in the UK,[20] and have an estimated annual production of 100 tons of medicinal cannabis since 2012.[21]

Products in development

Epidiolex

In 2015 GW Pharmaceutical initiated Phase 3 clinical trials of an investigational cannabidiol, Epidiolex, for treatment of two orphan conditions in children – Dravet and Lennox-Gastaut syndromes.[22] GW also received fast track designation from the US FDA for use of the drug candidate to treat newborns with epilepsy.[23]

See also

References

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External links

  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ http://www.guardian.co.uk/business/2011/apr/17/gw-pharmaceuticals-justin-gover-cannabis-sativex-multiple-sclerosis?INTCMP=SRCH The Observer, Sunday 17 April 2011)
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  8. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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  15. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  16. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  17. ↑ UK Medicines Online Nabiximols Page accessed Feb 3, 2016
  18. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  19. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  20. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  21. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  22. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  23. ↑ Tony Quested for Business Weekly. August 6, 2015 FDA backs cannabis-based medicine for in-danger newborns
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