Hopantenic acid

From Infogalactic: the planetary knowledge core
Jump to: navigation, search
Hopantenic acid
Stereo, skeletal formula of hopantenic acid
Hopantenic acid ball-and-stick.png
Names
IUPAC name
4-{[(2R)-2,4-Dihydroxy-3,3-dimethylbutanoyl]amino}butanoic acid[citation needed]
Identifiers
18679-90-8 YesY
17097-76-6 (Calcium salt) YesY
ChEMBL ChEMBL2110783
ChemSpider 26309 YesY
Jmol 3D model Interactive image
Interactive image
KEGG D08042 YesY
PubChem 28281
  • InChI=1S/C10H19NO5/c1-10(2,6-12)8(15)9(16)11-5-3-4-7(13)14/h8,12,15H,3-6H2,1-2H3,(H,11,16)(H,13,14)/t8-/m0/s1 YesY
    Key: SBBDHANTMHIRGW-QMMMGPOBSA-N YesY
  • CC(C)(CO)[C@@H](O)c(:[o]):[nH]CCCc(:[o]):[oH]
  • CC(C)(CO)[C@@H](O)C(=O)NCCCC(O)=O
Properties
C10H19NO5
Molar mass 233.26 g·mol−1
Related compounds
Related alkanoic acids
Related compounds
Panthenol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Hopantenic acid (homopantothenic acid), also known as N-pantoyl-GABA, is a central nervous system depressant. Formulated as the calcium salt, it is used as a pharmaceutical drug in the Russian Federation for a variety of neurological, psychological and psychiatric conditions and sold as Pantogam (Russian: Пантогам).[1] It is not approved for use in Europe or the United States.

Chemistry

Hopantenic acid is a homologue of pantothenic acid. While pantothenic acid is the amide of D-pantoate and β-alanine, hopantenic acid is the amide of D-pantoate and γ-aminobutyric acid (GABA). This change leads to an additional CH2 in the molecule.[2]

See also

References

  1. Pantogam, drugs.com
  2. Lua error in package.lua at line 80: module 'strict' not found.

External links