Mestranol/noretynodrel

Mestranol/noretynodrel

File:EnovidBottle.png Enovid first came in a bottle.
Combination of
Mestranol	Estrogen
Norethynodrel	Progestogen
Clinical data
Trade names	Enavid, Enovid
Legal status	Discontinued
Routes of administration	Oral
Identifiers
ATC code	G03FA09 (WHO)
PubChem	CID: 66444

Mestranol/noretynodrel was the first combined oral contraceptive pill (COCP) being mestranol and noretynodrel (INNs). It sold as Enovid in the United States and as Enavid in the United Kingdom. Developed by Dr. Gregory Pincus at G. D. Searle & Company, it was first approved on June 10, 1957 by the U.S. Food and Drug Administration for treatment of menstrual disorders. The FDA approved an additional indication for use as a contraceptive on June 23, 1960. In 1961, it was approved as a contraceptive in the UK and in Canada.

Enovid was discontinued in the U.S. in 1988, along with other first-generation high-estrogen COCPs.

See also

• Oral contraceptive formulations