Rhodopsin kinase

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G protein-coupled receptor kinase 1
Identifiers
Symbol GRK1
Alt. symbols RHOK
Entrez 6011
HUGO 10013
OMIM 180381
RefSeq NM_002929
UniProt Q15835
Other data
EC number 2.7.11.14
Locus Chr. 13 q34

Rhodopsin kinase (EC 2.7.11.14, cone opsin kinase, G-protein-coupled receptor kinase 1, GPCR kinase 1, GRK1, GRK7, opsin kinase, opsin kinase (phosphorylating), rhodopsin kinase (phosphorylating), RK, STK14) is a serine/threonine-specific protein kinase involved in phototransduction.[1][2][3][4][5][6][7][8] This enzyme catalyses the following chemical reaction

ATP + rhodopsin \rightleftharpoons ADP + phosphorhodopsin

Mutations in rhodopsin kinase are associated with a form of night blindness called Oguchi disease.[9]

See also

References

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External links

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