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October 2024

Cover

Ticks often infect the common bent-wing bat (Miniopterus schreibersii). Szentiványi et al highlight that the role of bat ticks as disease vectors should be urgently re-evaluated in more diverse host systems, as they may contribute to pathogen transmission between bats and non-chiropteran hosts.

Image Credit: Attila D. Sándor

Viewpoints

Electroencephalography in emerging viral infections: Lessons learned from implementing an EEG unit in a Lassa fever isolation ward in Nigeria

Hannah Caroline Sophie Mueller, Cyril Oshomah Erameh, Mathias Gelderblom, Osahogie Isaac Edeawe, Osetohamen Grace Akpasubi, Ekpen Uwayeme Ekoyata, Ujiagbe Moses Aiterebhe, Joseph Okoeguale, Stephan Guenther, Lisa Oestereich, Michael Ramharter, Sylvanus Okogbenin, Till Omansen

Need for a paradigm shift in soil-transmitted helminthiasis control: Targeting the right people, in the right place, and with the right drug(s)

Paul M. Emerson, Darin Evans, Matthew C. Freeman, Christy Hanson, Khumbo Kalua, Jennifer Keiser, Alejandro Krolewiecki, Lynn Leonard, Bruno Levecke, Sultani Matendechero, Arianna Rubin Means, Antonio Montresor, Denise Mupfasoni, Rachel L. Pullan, Lisa A. Rotondo, Mariana Stephens, Kristin M. Sullivan, Judd L. Walson, Tijana Williams, Jürg Utzinger

Policy Platform

A global chromoblastomycosis strategy and development of the global chromoblastomycosis working group

Dallas J. Smith, Flávio Queiroz-Telles, Fahafahantsoa Rapelanoro Rabenja, Roderick Hay, Alexandro Bonifaz, Marlous L. Grijsen, Romain Blaizot, Fernando Messina, Yinggai Song, Shawn R. Lockhart, Alexander Jordan, Alyson M. Cavanaugh, Anastasia P. Litvintseva, Tom Chiller, Marco Schito, Sybren de Hoog, Vania Aparecida Vicente, Muriel Cornet, Daniel Argaw Dagne, Lala S. Ramarozatovo, Conceição de Maria Pedrozo e Silva de Azevedo, Daniel Wagner C. L. Santos

Reviews

Diversity of Chagas disease diagnostic antigens: Successes and limitations

Tapan Bhattacharyya, Niamh Murphy, Michael A. Miles

Development and longevity of naturally acquired antibody and memory B cell responses against Plasmodium vivax infection

Pongsakorn Thawornpan, Piyawan Kochayoo, Zulfa Zahra Salsabila, Patchanee Chootong

Research Articles

A murine experimental model of the pulmonary thrombotic effect induced by the venom of the snake Bothrops lanceolatus

Alexandra Rucavado, Erika Camacho, Teresa Escalante, Bruno Lomonte, Julián Fernández, Daniela Solano, Isabel Quirós-Gutiérrez, Gabriel Ramírez-Vargas, Karol Vargas, Ivette Argüello, Alejandro Navarro, Carlos Abarca, Álvaro Segura, Jonathan Florentin, Hatem Kallel, Dabor Resiere, Remi Neviere, José María Gutiérrez

Using Acanthamoeba spp. as a cell model to evaluate Leishmania infections

Helena Lúcia Carneiro Santos, Gabriela Linhares Pereira, Rhagner Bonono do Reis, Igor Cardoso Rodrigues, Claudia Masini d’Avila, Vitor Ennes Vidal

Involvement of INS15 in the development and pathogenicity of the zoonotic pathogen Cryptosporidium parvum

Wei He, Hao Cui, Na Li, Yaqiong Guo, Songrong Zeng, Yaoyu Feng, Lihua Xiao, Rui Xu

Evaluation of Aedes aegypti control intervention with pyriproxyfen by lcWGS in Manacapuru, Amazonas, Brazil

Lorena Ferreira de Oliveira Leles, Marcus Vinicius Niz Alvarez, Jose Joaquin Carvajal Cortés, Diego Peres Alonso, Paulo Eduardo Martins Ribolla, Sérgio Luiz Bessa Luz

Trends in antimicrobial resistance amongst Salmonella Typhi in Bangladesh: A 24-year retrospective observational study (1999–2022)

Arif Mohammad Tanmoy, Yogesh Hooda, Mohammad Saiful Islam Sajib, Hafizur Rahman, Anik Sarkar, Dipu Das, Nazrul Islam, Naito Kanon, Md. Asadur Rahman, Denise O. Garrett, Hubert P. Endtz, Stephen P. Luby, Mohammod Shahidullah, Md. Ruhul Amin, Jahangir Alam, Mohammed Hanif, Samir K. Saha, Senjuti Saha

A scoping review of evidence of naturally occurring Japanese encephalitis infection in vertebrate animals other than humans, ardeid birds and pigs

Zoë A. Levesque, Michael G. Walsh, Cameron E. Webb, Ruth N. Zadoks, Victoria J. Brookes

Navigating cross-reactivity and host species effects in a serological assay: A case study of the microscopic agglutination test for Leptospira serology

Riley O. Mummah, Ana C. R. Gomez, Angela H. Guglielmino, Benny Borremans, Renee L. Galloway, Katherine C. Prager, James O. Lloyd-Smith

An integrated active case detection and management of skin NTDs in yaws endemic health districts in Cameroon, Côte d’Ivoire and Ghana

Serges Tchatchouang, Laud A. Basing, Hugues Kouadio-Aboh, Becca L. Handley, Camila G-Beiras, Ivy Amanor, Philippe Ndzomo, Mohammed Bakheit, Lisa Becherer, Sascha Knauf, Claudia Müller, Earnest Njih-Tabah, Theophilus Njamnshi, Tania Crucitti, Nadine Borst, Simone Lüert, Sieghard Frischmann, Helena Gmoser, Emelie Landmann, Aboubacar Sylla, Mireille S. Kouamé-Sina, Daniel Arhinful, Patrick Awondo, Gely Menguena, Emma-Michèle Harding-Esch, Adingra Tano, Mamadou Kaloga, Paul Koffi-Aboa, Nana Konama-Kotey, Oriol Mitjà, Sara Eyangoh, Kennedy Kwasi-Addo, Solange Ngazoa-Kakou, Michael Marks

Use of an inertial sensor and a force platform to assess static balance in participants affected by multibacillary leprosy

Aymee Lobato Brito, Amelia Pasqual Marques, Yuzo Igarashi, Luana Karine Resende Oliveira, Luciane Lobato Sobral, Marília Brasil Xavier, Givago Silva Souza, Bianca Callegari

Molecular epidemiology and population genetics of Schistosoma mansoni infecting school-aged children situated along the southern shoreline of Lake Malawi, Malawi

John Archer, Lucas J. Cunningham, Alexandra Juhász, Sam Jones, Angus M. O’Ferrall, Sarah Rollason, Bright Mainga, Priscilla Chammudzi, Donales R. Kapira, David Lally, Gladys Namacha, Peter Makaula, James E. LaCourse, Sekeleghe A. Kayuni, Bonnie L. Webster, Janelisa Musaya, J. Russell Stothard

Auranofin is active against Histoplasma capsulatum and reduces the expression of virulence-related genes

Marcos de Abreu Almeida, Lilian Cristiane Baeza, Leandro B. R. Silva, Andréa Reis Bernardes-Engemann, Fernando Almeida-Silva, Rowena Alves Coelho, Iara Bastos de Andrade, Dario Corrêa-Junior, Susana Frases, Rosely Maria Zancopé-Oliveira, Alexandre Alanio, Carlos Pelleschi Taborda, Rodrigo Almeida-Paes

Community-Based Mycetoma Surveillance in Uganda: Identifying Knowledge Gaps and Training of Community Health Workers to Improve Case Detection

Winnie Kibone, Andrew Weil Semulimi, Richard Kwizera, Felix Bongomin

Evaluating alternative compounds for strongyloidiasis therapy: Novel insights from larval migration inhibition test

María Cambra-Pellejà, Elora Valderas-García, Rafael Balaña-Fouce, Jennifer de la Vega, Esther del Olmo, Jennifer Antwi-Ekwuruke, Lara Linnemann, Lennart Heepmann, Minka Breloer, María Martínez-Valladares

Estimating the force of infection of four dengue serotypes from serological studies in two regions of Vietnam

Huynh Thi Phuong, Nguyen Ha Thao Vy, Nguyen Thi Le Thanh, Maxine Tan, Erwin de Bruin, Marion Koopmans, Maciej F. Boni, Hannah E. Clapham

Validation of the performance of a point of care molecular test for leprosy: From a simplified DNA extraction protocol to a portable qPCR

Amanda Bertão-Santos, Larisse da Silva Dias, Marcelo Ribeiro-Alves, Roberta Olmo Pinheiro, Milton Ozório Moraes, Fernanda Saloum de Neves Manta, Alexandre Dias Tavares Costa

A multi-pathogen behavioral exposure model for young children playing in public spaces in developing communities

Stephanie A. Houser, Daniel K. Sewell, Danielle N. Medgyesi, John M. Brogan, Jean Philippe Creve-Coeur, Kelly K. Baker

Incidence and persistence of asymptomatic Leishmania infection among HIV-infected patients in Trang province, Southern Thailand: A cohort study

Lertwut Bualert, Toon Ruang-areerate, Mathirut Mungthin, Saovanee Leelayoova, Suradej Siripattanapipong, Tawee Naaglor, Nattapong Hongsimakul, Supicha Sroythong, Phakhajee Rattanalertpaiboon, Preeyaporn Tulpeng, Phunlerd Piyaraj

Orthohantavirus diversity in Central-East Argentina: Insights from complete genomic sequencing on phylogenetics, Geographic patterns and transmission scenarios

Daniel Oscar Alonso, Sebastián Dario Kehl, Rocío María Coelho, Natalia Periolo, Tomás Poklépovich Caride, Julián Sanchez Loria, Facundo Gabriel Cuba, Unai Pérez-Sautu, Mariano Sanchez-Lockhart, Gustavo Palacios, Carla Maria Bellomo, Valeria Paula Martinez

A systematic review and meta-analysis of the prevalence of tick-borne SFGR in China from 2000 to 2022

Yanchao Hu, Ting Yin, Wei Ma, Jiangwei Qiu, Jiaxing Zhang, Qingan Wang

Household expenditure on control of urban mosquitoes Aedes albopictus and Culex pipiens in Emilia-Romagna, Northern Italy

Massimo Canali, Laura Vici, Stefano Rivas Morales, Luciano Donati, Carmela Matrangolo, Claudio Venturelli, Paola Angelini, Michele Dottori, Romeo Bellini, Marco Carrieri

Usefulness of next-generation sequencing for laboratory diagnosis of rickettsiosis

Fanfan Xing, Chaowen Deng, Jinyue Huang, Yanfei Yuan, Zhendong Luo, Simon K. F. Lo, Susanna K. P. Lau, Patrick C. Y. Woo

Branched-chain amino acids modulate the proteomic profile of Trypanosoma cruzi metacyclogenesis induced by proline

Janaina de Freitas Nascimento, Flávia Silva Damasceno, Sabrina Marsiccobetre, Francisca Natália de Luna Vitorino, Renan Weege Achjian, Julia Pinheiro Chagas da Cunha, Ariel Mariano Silber

Evaluation of a novel biplex rapid diagnostic test for antibody responses to Loa loa and Onchocerca volvulus infections

Jérémy T. Campillo, Marco A. Biamonte, Marlhand C. Hemilembolo, François Missamou, Michel Boussinesq, Sébastien D. S. Pion, Cédric B. Chesnais

Age, period, and cohort effects of Clonorchis sinensis infection prevalence in the Republic of Korea: Insights and projections

Sung-mok Jung, Heewon Kang, Bong-Kwang Jung, Sejin Ju, Jung-Won Ju, Myoung-Ro Lee, Jong-hun Kim, Sung Hye Kim

Diagnostic serology test comparison for Q fever and Rift Valley fever in humans and livestock from pastoral communities

Valerie Hungerbühler, Ranya Özcelik, Mahamat Fayiz Abakar, Fatima Abdelrazak Zakaria, Martin Eiden, Sonja Hartnack, Pidou Kimala, Sonja Kittl, Janine Michel, Franziska Suter-Riniker, Salome Dürr

Risk factors of thromboembolic events in patients with scrub typhus

Young Jae Ki, Sung Soo Kim, Jun-Won Seo, Da Young Kim, Na Ra Yun, Choon-Mee Kim, Dong-Min Kim

General public knowledge, attitudes, and practices about rabies and associated factors in Gomma district of Jimma zone, southwestern Ethiopia

Shimelis Kebede, Gashaw Beyene, Biruk Akalu, Elias AbaJebel, Isayas Asefa Kebede

The economic burden of visceral leishmaniasis and barriers to accessing healthcare in Tigray, North Ethiopia: A field based study

Shewaye Belay Tessema, Tadyos Hagos, Genet Kehasy, Lucy Paintain, Cherinet Adera, Merce Herrero, Margriet den Boer, Haftom Temesgen, Helen Price, Afework Mulugeta

Gut-microbiome profiles among Soil-transmitted helminths (STHs) infected Ethiopian children enrolled in the school-based mass deworming program

Bineyam Taye, Zeleke Mekonnen, Kenneth D. Belanger, Emily R. Davenport

Video-observed therapy (VOT) vs directly observed therapy (DOT) for tuberculosis treatment: A systematic review on adherence, cost of treatment observation, time spent observing treatment and patient satisfaction

Thiago Areas Lisboa Netto, Bruna Dellatorre Diniz, Peter Odutola, Clara Rocha Dantas, Maria Carolina Fonseca Loureiro Caldeira de Freitas, Philip Michael Hefford, Taniela Marli Bes

Short-term associations of diarrhoeal diseases in children with temperature and precipitation in seven low- and middle-income countries from Sub-Saharan Africa and South Asia in the Global Enteric Multicenter Study

Nasif Hossain, Lina Madaniyazi, Chris Fook Sheng Ng, Dilruba Nasrin, Xerxes Tesoro Seposo, Paul L. C. Chua, Rui Pan, Abu Syed Golam Faruque, Masahiro Hashizume

Role of the type 6 secretion system on apoptosis and macrophage polarization during Burkholderia pseudomallei infection

Jacob L. Stockton, Nittaya Khakhum, Alfredo G. Torres

Crimean-Congo hemorrhagic fever cases diagnosed during an outbreak of Sudan virus disease in Uganda, 2022–23

Stephen Balinandi, Sophia Mulei, Shannon Whitmer, Luke Nyakarahuka, Caitlin M. Cossaboom, Elizabeth Shedroff, Maria Morales-Betoulle, Inna Krapiunaya, Alex Tumusiime, Jackson Kyondo, Jimmy Baluku, Dianah Namanya, Calvin R. Torach, Joanita Mutesi, Jocelyn Kiconco, Godfrey Pimundu, Tonny Muyigi, Jessica Rowland, Andrew Nsawotebba, Isaac Ssewanyana, David Muwanguzi, Daniel Kadobera, Julie R. Harris, Alex R. Ario, Kagirita Atek, Henry B. Kyobe, Susan Nabadda, Pontiano Kaleebu, Henry G. Mwebesa, Joel M. Montgomery, Trevor R. Shoemaker, Julius J. Lutwama, John D. Klena

Metatranscriptomic insights into the dengue patient blood microbiome: Enhanced microbial diversity and metabolic activity in severe patients

Aanchal Yadav, Priti Devi, Pallawi Kumari, Uzma Shamim, Bansidhar Tarai, Sandeep Budhiraja, Rajesh Pandey

Zika virus T-cell based 704/DNA vaccine promotes protection from Zika virus infection in the absence of neutralizing antibodies

Claude Roth, Bruno Pitard, Laurine Levillayer, Sokchea Lay, Hoa Thi My Vo, Tineke Cantaert, Anavaj Sakuntabhai

Intraspecific venom variation in the medically important puff adder (Bitis arietans): Comparative venom gland transcriptomics, in vitro venom activity and immunological recognition by antivenom

Charlotte A. Dawson, Keirah E. Bartlett, Mark C. Wilkinson, Stuart Ainsworth, Laura-Oana Albulescu, Taline Kazandijan, Steven R. Hall, Adam Westhorpe, Rachel Clare, Simon Wagstaff, Cassandra M. Modahl, Robert A. Harrison, Nicholas R. Casewell

Clinical characteristics and prognosis of Talaromycosis marneffei associated immune reconstitution inflammatory syndrome in AIDS patients

Qinzhi Zhang, Huihua Zhang, Pengle Guo, Weiyin Lin, Feilong Xu, Xiaoping Tang, Linghua Li

Serological evidence of tick-borne Crimean-Congo haemorrhagic fever and Dugbe orthonairovirus infections in cattle in Kwara State in northern Nigeria indicate independent endemics

Oluwafemi Babatunde Daodu, Julia Hartlaub, James Olukayode Olopade, Daniel Oladimeji Oluwayelu, Martin H. Groschup

Little disease but lots of bites: social, urbanistic, and entomological risk factors of human exposure to Aedes aegypti in South Texas, U.S.

Nicole A. Scavo, Jose G. Juarez, Luis Fernando Chaves, Nadia A. Fernández-Santos, Ester Carbajal, Joshuah Perkin, Berlin Londono-Renteria, Gabriel L. Hamer

Hybrid Machine Learning Approach to Zero-Inflated Data Improves Accuracy of Dengue Prediction

Micanaldo Ernesto Francisco, Thaddeus M. Carvajal, Kozo Watanabe

Uncovering intersecting stigmas experienced by people affected by podoconiosis in Nyamasheke district, Rwanda

Jean Paul Bikorimana, Gail Davey, Josephine Mukabera, Zaman Shahaduz, Peter J. Mugume, Papreen Nahar

REIV-TOXO Project: Results from a Spanish cohort of congenital toxoplasmosis (2015–2022). The beneficial effects of prenatal treatment on clinical outcomes of infected newborns

Borja Guarch-Ibáñez, Clara Carreras-Abad, Marie Antoinette Frick, Daniel Blázquez-Gamero, Fernando Baquero-Artigao, Isabel Fuentes, the Spanish Research Network of Congenital Toxoplasmosis (REIV-TOXO) group, Pere Soler-Palacin

Ghrelin is involved in regulating the progression of Echinococcus Granulosus-infected liver lesions through suppression of immunoinflammation and fibrosis

Jiang Zhu, Hongqiong Zhao, Aili Aierken, Tanfang Zhou, Meng Menggen, Huijing Gao, Rongdong He, Kalibixiati Aimulajiang, Hao Wen

The characteristics and clinical course of patients with melioidosis and cancer

Tej Shukla, Simon Smith, Kristoffer Johnstone, Patrick Donald, Josh Hanson

Bat-associated ticks as a potential link for vector-borne pathogen transmission between bats and other animals

Tamara Szentiványi, Nóra Takács, Attila D. Sándor, Áron Péter, Sándor A. Boldogh, Dávid Kováts, Jeffrey T. Foster, Péter Estók, Sándor Hornok

High prevalence of porcine cysticercosis in slaughtered pigs in Rwanda: An abattoir survey

Anselme Shyaka, Nadine Rujeni, Eric I. Kanyamibwa, Geofrey Kagabo, Eric M. Fèvre, Rupert J. Quinnell

Bacillus thuringiensis Cry14A family proteins as novel anthelmintics against gastrointestinal nematode parasites

Duy Hoang, Kelly Flanagan, Qian Ding, Nicholas R. Cazeault, Hanchen Li, Stefani Díaz-Valerio, Florentina Rus, Esther A. Darfour, Elizabeth Kass, Katherine H. Petersson, Martin K. Nielsen, Heiko Liesegang, Gary R. Ostroff, Raffi V. Aroian

Economic cost of a case of diarrhoea in Uvira, Democratic Republic of the Congo: A cost of illness study

Patrick V. Katana, Espoir Bwenge Malembaka, Patrick Musole Bugeme, Jaime Mufitini Saidi, Oliver Cumming, Karin Gallandat, Ian Ross

Intracranial inoculation rapidly induces Nipah virus encephalitis in Syrian hamsters

Manmeet Singh, Kerry Goldin, Meaghan Flagg, Brandi N. Williamson, Tessa Lutterman, Brian Smith, Emmie de Wit

Intra-specific variations in Schistosoma mansoni and their possible contribution to inconsistent virulence and diverse clinical outcomes

Tim A. Dannenhaus, Franziska Winkelmann, Cindy Reinholdt, Miriam Bischofsberger, Jan Dvořák, Christoph G. Grevelding, Micha Löbermann, Emil C. Reisinger, Martina Sombetzki

Extracellular vesicles of Clonorchis sinensis promote the malignant phenotypes of cholangiocarcinoma via NF-κB/EMT axis

Xiaowen Pan, Qing He, Yingxuan Yin, Anyuan Xu, Aoxun Wu, Xueqing Yi, Zifeng Zhong, Yinjuan Wu, Xuerong Li

Polarization toward Tfh2 cell involved in development of MBC and antibody responses against Plasmodium vivax infection

Pongsakorn Thawornpan, Zulfa Zahra Salsabila, Piyawan Kochayoo, Tipanan Khunsri, Chayapat Malee, Kittikorn Wangriatisak, Chaniya Leepiyasakulchai, Francis Babila Ntumngia, John H. Adams, Patchanee Chootong

Insights into trypanosomiasis transmission: Age, infection rates, and bloodmeal analysis of Glossina fuscipes fuscipes in N.W. Uganda

Lucas J. Cunningham, Johan Esterhuizen, John W. Hargrove, Mike Lehane, Jennifer Lord, Jessica Lingley, T. N. Clement Mangwiro, Mercy Opiyo, Iñaki Tirados, Steve J. Torr

Recurrence patterns and evolution of submicroscopic and asymptomatic Plasmodium vivax infections in malaria-endemic areas of the Peruvian Amazon

Stefano S. Garcia Castillo, Caroline Abanto Alvarez, Ángel Rosas-Aguirre, Carlos Acosta, Rodrigo M. Corder, Joaquín Gómez, Mitchel Guzmán, Niko Speybroeck, Alejandro Llanos-Cuentas, Marcia C. Castro, Anna Rosanas-Urgell, Marcelo U. Ferreira, Joseph M. Vinetz, Dionicia Gamboa, Katherine Torres

Temperature and photoperiod differentially impact maternal phenotypes in diapause egg-laying Aedes albopictus mosquitoes

In Hae Lee, Anthony S. Lee, Helen V. Kogan, Linhan Dong, Laura B. Duvall

Spatiotemporal Distribution of Human Rabies and Identification of Predominant Risk Factors in China from 2004 to 2020

Weiwei Meng, Tianren Shen, Okugbe Ebiotubo Ohore, Susan Christina Welburn, Guojing Yang

Detection and evolutionary characterization of arboviruses in mosquitoes and biting midges on Hainan Island, China, 2019–2023

Qun Wu, Dingwei Sun, Wahid Zaman, Fei Wang, Doudou Huang, Haixia Ma, Shunlong Wang, Ying Liu, Puyu Liu, Xuexia Zeng, Zhiming Yuan, Han Xia

A change in circulating chikungunya virus variant impacts Aedes aegypti vector competence and spatiotemporal distribution of disease in Malaysia

Izzati Kausar Azman, Yoke Fun Chan, Chong Long Chua, Zainal Abidin Abd Mutalib, Sarat Chandra Dass, Balvinder Singh Gill, Nor Hayati Ismail, Jenarun Jelip, Ming Keong Wan, Wenn-Chyau Lee, Indra Vythilingam, Luke Alphey, I-Ching Sam

Corrections