A Bothrops atrox (common lancehead) in a riverine community of the Western Brazilian Amazon, highlighting the importance of prevention and rapid response to snakebite envenoming (SBE). Santos et al, 2025.
Image Credit: Felipe Murta
Viewpoints
The growing challenge of arboviruses in Latin America: Dengue and Oropouche in focus
PLOS Neglected Tropical Diseases: published January 7, 2025 | https://doi.org/10.1371/journal.pntd.0012789
Target product profiles for pan-Africa recombinant antivenoms against neurotoxic or hemotoxic and cytotoxic snakebite envenoming
PLOS Neglected Tropical Diseases: published January 24, 2025 | https://doi.org/10.1371/journal.pntd.0012833
Policy Platform
Leptospirosis, melioidosis, and rickettsioses in the vicious circle of neglect
PLOS Neglected Tropical Diseases: published January 23, 2025 | https://doi.org/10.1371/journal.pntd.0012796
Reviews
Progress in antileishmanial drugs: Mechanisms, challenges, and prospects
PLOS Neglected Tropical Diseases: published January 3, 2025 | https://doi.org/10.1371/journal.pntd.0012735
A comprehensive review of biological and genetic control approaches for leishmaniasis vector sand flies; emphasis towards promoting tools for integrated vector management
PLOS Neglected Tropical Diseases: published January 27, 2025 | https://doi.org/10.1371/journal.pntd.0012795
Research Articles
Molecular xenomonitoring of Schistosoma mansoni infections in Biomphalaria choanomphala at Lake Victoria, East Africa: Assessing roles of abiotic and biotic factors
PLOS Neglected Tropical Diseases: published January 2, 2025 | https://doi.org/10.1371/journal.pntd.0012771
The first direct detection of spotted fever group Rickettsia spp. diversity in ticks from Ningxia, northwestern China
PLOS Neglected Tropical Diseases: published January 2, 2025 | https://doi.org/10.1371/journal.pntd.0012729
Human and entomological determinants of malaria transmission in the Lihir Islands of Papua New Guinea: A cross-sectional study
PLOS Neglected Tropical Diseases: published January 3, 2025 | https://doi.org/10.1371/journal.pntd.0012277
Malian field isolates provide insight into Plasmodium malariae intra-erythrocytic development and invasion
PLOS Neglected Tropical Diseases: published January 6, 2025 | https://doi.org/10.1371/journal.pntd.0012790
Toxoplasma gondii from Gabonese forest, Central Africa: First report of an African wild strain
PLOS Neglected Tropical Diseases: published January 6, 2025 | https://doi.org/10.1371/journal.pntd.0012214
First detection of the S989P+V1016G+D1763Y haplotype and expansion of voltage-gated sodium channel mutations in Aedes aegypti in Taiwan in 2016–2023
PLOS Neglected Tropical Diseases: published January 6, 2025 | https://doi.org/10.1371/journal.pntd.0012768
Effectiveness of carbon dioxide cryotherapy for the treatment of cutaneous leishmaniasis: Systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published January 6, 2025 | https://doi.org/10.1371/journal.pntd.0012741
Prevalence, intensity and risk factors of soil-transmitted helminthiasis after five effective rounds of preventive chemotherapy across three implementation units in Ondo State, Nigeria
PLOS Neglected Tropical Diseases: published January 6, 2025 | https://doi.org/10.1371/journal.pntd.0012533
A low pre-existing anti-NS1 humoral immunity to DENV is associated with microcephaly development after gestational ZIKV exposure
PLOS Neglected Tropical Diseases: published January 6, 2025 | https://doi.org/10.1371/journal.pntd.0012193
Human mobility and malaria risk in peri-urban and rural communities in the Peruvian Amazon
PLOS Neglected Tropical Diseases: published January 6, 2025 | https://doi.org/10.1371/journal.pntd.0012058
Genetic variation of hemolysin co-regulated protein 1 affects the immunogenicity and pathogenicity of Burkholderia pseudomallei
PLOS Neglected Tropical Diseases: published January 6, 2025 | https://doi.org/10.1371/journal.pntd.0012758
Pharmacological inhibition of key metabolic pathways attenuates Leishmania spp infection in macrophages
PLOS Neglected Tropical Diseases: published January 7, 2025 | https://doi.org/10.1371/journal.pntd.0012763
Identification of Environmental Determinants Involved in the Distribution of Burkholderia pseudomallei in Southeast Asia using MaxEnt software
PLOS Neglected Tropical Diseases: published January 7, 2025 | https://doi.org/10.1371/journal.pntd.0012684
Insecticide resistance mutations of Anopheles species in the Republic of Korea
PLOS Neglected Tropical Diseases: published January 7, 2025 | https://doi.org/10.1371/journal.pntd.0012748
Continuous detection of Chikungunya Virus in a passive surveillance system in southern Thailand, 2012–2019
PLOS Neglected Tropical Diseases: published January 7, 2025 | https://doi.org/10.1371/journal.pntd.0012776
Understanding reasons for delay in diagnosis of leprosy in Pakistan: A qualitative study
PLOS Neglected Tropical Diseases: published January 7, 2025 | https://doi.org/10.1371/journal.pntd.0012764
Chronic pulmonary aspergillosis in tea population of Assam
PLOS Neglected Tropical Diseases: published January 8, 2025 | https://doi.org/10.1371/journal.pntd.0012756
Developing and applying a training needs analysis tool for healthcare workers managing snakebite envenoming: A cross-sectional study in Eswatini
PLOS Neglected Tropical Diseases: published January 8, 2025 | https://doi.org/10.1371/journal.pntd.0012778
A new guide for basic psychological support for persons affected by neglected tropical diseases: A peer support tool suitable for persons with a diagnosis of leprosy and lymphatic filariasis
PLOS Neglected Tropical Diseases: published January 9, 2025 | https://doi.org/10.1371/journal.pntd.0011945
Using ESPEN data for evidence-based control of neglected tropical diseases in sub-Saharan Africa: A comprehensive model-based geostatistical analysis of soil-transmitted helminths
PLOS Neglected Tropical Diseases: published January 9, 2025 | https://doi.org/10.1371/journal.pntd.0012782
Effect of health education in the control of schistosomiasis in Dass Emirate Council of Bauchi State, Nigeria: An intervention study
PLOS Neglected Tropical Diseases: published January 9, 2025 | https://doi.org/10.1371/journal.pntd.0012358
Exploring barriers to accessing treatment for Lymphatic Filariasis through a socio-ecological lens in Buvuma and Napak districts, Uganda
PLOS Neglected Tropical Diseases: published January 9, 2025 | https://doi.org/10.1371/journal.pntd.0012747
Development and validation of a high-throughput qPCR platform for the detection of soil-transmitted helminth infections
PLOS Neglected Tropical Diseases: published January 10, 2025 | https://doi.org/10.1371/journal.pntd.0012760
Altering the intracellular trafficking of Necator americanus GST-1 antigen yields novel hookworm mRNA vaccine candidates
PLOS Neglected Tropical Diseases: published January 10, 2025 | https://doi.org/10.1371/journal.pntd.0012809
Congenital Chagas disease: A cohort study to assess molecular diagnostic methods at the Chagas disease national reference center of Argentina
PLOS Neglected Tropical Diseases: published January 10, 2025 | https://doi.org/10.1371/journal.pntd.0012785
Insect-specific RNA viruses detection in Field-Caught Aedes aegypti mosquitoes from Argentina using NGS technology
PLOS Neglected Tropical Diseases: published January 10, 2025 | https://doi.org/10.1371/journal.pntd.0012792
Associations of resuscitation fluid load, colloid-to-crystalloid infusion ratio and clinical outcomes in children with dengue shock syndrome
PLOS Neglected Tropical Diseases: published January 10, 2025 | https://doi.org/10.1371/journal.pntd.0012786
Dengue severity by serotype and immune status in 19 years of pediatric clinical studies in Nicaragua
PLOS Neglected Tropical Diseases: published January 10, 2025 | https://doi.org/10.1371/journal.pntd.0012811
Baseline infection prevalence, risk factors and treatment outcomes of visceral leishmaniasis in Northeastern Uganda: A cross-sectional study
PLOS Neglected Tropical Diseases: published January 13, 2025 | https://doi.org/10.1371/journal.pntd.0012783
Distribution and viability of ocular and non-ocular Chlamydia trachomatis in households in a trachoma-endemic community in Oromia, Ethiopia
PLOS Neglected Tropical Diseases: published January 13, 2025 | https://doi.org/10.1371/journal.pntd.0012759
Stage-specific expression and divergent functions of two insulinase-like proteases associated with host infectivity in Cryptosporidium
PLOS Neglected Tropical Diseases: published January 13, 2025 | https://doi.org/10.1371/journal.pntd.0012777
Early therapy contributes to the normalization of platelet in patients with severe fever with thrombocytopenia syndrome during the convalescent phase
PLOS Neglected Tropical Diseases: published January 13, 2025 | https://doi.org/10.1371/journal.pntd.0012793
Contribution of epidermal growth factor (EGF) in the treatment of cutaneous leishmaniasis caused by Leishmania major in BALB/c mice
PLOS Neglected Tropical Diseases: published January 14, 2025 | https://doi.org/10.1371/journal.pntd.0012765
Determinants of viral haemorrhagic fever risk in Africa’s tropical moist forests: A scoping review of spatial, socio-economic, and environmental factors
PLOS Neglected Tropical Diseases: published January 16, 2025 | https://doi.org/10.1371/journal.pntd.0012817
Machine learning and spatio-temporal analysis of meteorological factors on waterborne diseases in Bangladesh
PLOS Neglected Tropical Diseases: published January 16, 2025 | https://doi.org/10.1371/journal.pntd.0012800
Spatio-temporal risk prediction of leptospirosis: A machine-learning-based approach
PLOS Neglected Tropical Diseases: published January 16, 2025 | https://doi.org/10.1371/journal.pntd.0012755
Nb-FAR-1: A key developmental protein affects lipid droplet accumulation and cuticle formation in Nippostrongylus brasiliensis
PLOS Neglected Tropical Diseases: published January 17, 2025 | https://doi.org/10.1371/journal.pntd.0012769
Proteomic characterization and comparison of the infective and adult life stage secretomes from Necator americanus and Ancylostoma ceylanicum
PLOS Neglected Tropical Diseases: published January 20, 2025 | https://doi.org/10.1371/journal.pntd.0012780
Scrub typhus in pregnancy: A 10-year multicenter study in resource-limited settings in China
PLOS Neglected Tropical Diseases: published January 21, 2025 | https://doi.org/10.1371/journal.pntd.0012829
Longitudinal observational (single cohort) study on the causes of trypanocide failure in cases of African animal trypanosomosis in cattle near wildlife protected areas of Northern Tanzania
PLOS Neglected Tropical Diseases: published January 21, 2025 | https://doi.org/10.1371/journal.pntd.0012541
Incompatible Aedes aegypti male releases as an intervention to reduce mosquito population—A field trial in Puerto Rico
PLOS Neglected Tropical Diseases: published January 21, 2025 | https://doi.org/10.1371/journal.pntd.0012839
Heterogeneous zonal impacts of climate change on a wide hyperendemic area of human and animal fascioliasis assessed within a One Health action for prevention and control
PLOS Neglected Tropical Diseases: published January 21, 2025 | https://doi.org/10.1371/journal.pntd.0012820
A CRISPR-Cas12a-based universal rapid scrub typhus diagnostic method targeting 16S rRNA of Orientia tsutsugamushi
PLOS Neglected Tropical Diseases: published January 22, 2025 | https://doi.org/10.1371/journal.pntd.0012826
Development of a novel multi-epitope mRNA vaccine candidate to combat SFTSV pandemic
PLOS Neglected Tropical Diseases: published January 22, 2025 | https://doi.org/10.1371/journal.pntd.0012815
Vaccination of mice with Trichinella spiralis C-type lectin elicited the protective immunity and enhanced gut epithelial barrier function
PLOS Neglected Tropical Diseases: published January 22, 2025 | https://doi.org/10.1371/journal.pntd.0012825
Participatory research towards the control of snakebite envenoming and other illnesses in a riverine community of the Western Brazilian Amazon
PLOS Neglected Tropical Diseases: published January 23, 2025 | https://doi.org/10.1371/journal.pntd.0012840
Trichinella spiralis excretory/secretory proteins mediated larval invasion via inducing gut epithelial apoptosis and barrier disruption
PLOS Neglected Tropical Diseases: published January 23, 2025 | https://doi.org/10.1371/journal.pntd.0012842
Detection and analysis of Serpin and RP26 specific antibodies for monitoring Schistosoma haematobium transmission
PLOS Neglected Tropical Diseases: published January 24, 2025 | https://doi.org/10.1371/journal.pntd.0012813
Natural exposure to Chikungunya virus in golden-headed lion tamarin (Leontopithecus chrysomelas, Kuhl, 1820) from non-protected areas in southern Bahia, Brazil: Implications and significance
PLOS Neglected Tropical Diseases: published January 24, 2025 | https://doi.org/10.1371/journal.pntd.0012695
Development and characterization of a reverse genetics system for the lineage II Chicava strain of Machupo virus in a guinea pig model
PLOS Neglected Tropical Diseases: published January 24, 2025 | https://doi.org/10.1371/journal.pntd.0012834
Meta-analyses of Culex blood-meals indicates strong regional effect on feeding patterns
PLOS Neglected Tropical Diseases: published January 24, 2025 | https://doi.org/10.1371/journal.pntd.0012245
Triatoma venosa and Panstrongylus geniculatus challenge the certification of interruption of vectorial Trypanosoma cruzi transmission by Rhodnius prolixus in eastern Colombia
PLOS Neglected Tropical Diseases: published January 27, 2025 | https://doi.org/10.1371/journal.pntd.0012822
The Japanese encephalitis virus NS1′ protein facilitates virus infection in mosquitoes
PLOS Neglected Tropical Diseases: published January 27, 2025 | https://doi.org/10.1371/journal.pntd.0012823
Case-area targeted interventions and free chlorine residual in household drinking water: An observational cohort study during a cholera outbreak in Northeast Nigeria
PLOS Neglected Tropical Diseases: published January 27, 2025 | https://doi.org/10.1371/journal.pntd.0012731
Alternative approaches for monitoring and evaluation of lymphatic filariasis following mass drug treatment with ivermectin, diethylcarbamazine and albendazole in East New Britain Province, Papua New Guinea
PLOS Neglected Tropical Diseases: published January 27, 2025 | https://doi.org/10.1371/journal.pntd.0012128
Potential links between human bloodstream infection by Salmonella enterica serovar Typhimurium and international transmission to Colombia
PLOS Neglected Tropical Diseases: published January 28, 2025 | https://doi.org/10.1371/journal.pntd.0012801
Prognostic factors in severe dengue patients: A multi-center retrospective cohort study
PLOS Neglected Tropical Diseases: published January 28, 2025 | https://doi.org/10.1371/journal.pntd.0012846
Near-infrared spectroscopy discriminates mass-reared sterile and wild tsetse flies
PLOS Neglected Tropical Diseases: published January 29, 2025 | https://doi.org/10.1371/journal.pntd.0012857
Scrub typhus association with autoimmune biomarkers and clinical implications
PLOS Neglected Tropical Diseases: published January 29, 2025 | https://doi.org/10.1371/journal.pntd.0012766
Sensitivity of anti-filarial antibodies for lymphatic filariasis surveillance: Insights from a serological survey in Samoa in 2018
PLOS Neglected Tropical Diseases: published January 30, 2025 | https://doi.org/10.1371/journal.pntd.0012835
Concurrent transmission of Zika virus during the 2023 dengue outbreak in Dhaka, Bangladesh
PLOS Neglected Tropical Diseases: published January 30, 2025 | https://doi.org/10.1371/journal.pntd.0012866
Genomic characterization of antimicrobial-resistance and virulence factors in Salmonella isolates obtained from pig farms in Antioquia, Colombia
PLOS Neglected Tropical Diseases: published January 31, 2025 | https://doi.org/10.1371/journal.pntd.0012830
Rabies seropositive individuals, dogs, and healthcare professionals without prior vaccination in four Brazilian Indigenous communities
PLOS Neglected Tropical Diseases: published January 31, 2025 | https://doi.org/10.1371/journal.pntd.0012850
Correction
Correction: Design and expression of a chimeric recombinant antigen (SsIR-Ss1a) for the serodiagnosis of human strongyloidiasis: Evaluation of performance, sensitivity, and specificity
PLOS Neglected Tropical Diseases: published January 29, 2025 | https://doi.org/10.1371/journal.pntd.0012838