Targeted Drug Delivery
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Recent papers in Targeted Drug Delivery
A system is described here that can noninvasively control the navigation of freely behaving rat via ultrasonic, epidermal and LED photic stimulators on the back. The system receives commands from a remote host computer to deliver... more
Nanomedicine: History and origin; Applications of nanomedicine ; Medical nanomaterials and nanodevices; Advantages and Disadvantages; Nanotixicity; Future prospects; Conclusion
A series of novel nanogels (NGs) with both pH and thermoresponsive properties were synthesised by free radical emulsion polymerisation of N-vinyl caprolactam (VCL) and acrylamidoglycolic acid (AGA). 5-Flurouracil, an anti cancer drug, was... more
The combination of an efficient encapsulation method of small water-soluble substances with a stimuli-responsive release of defined quantity remains a challenging task. A novel drug delivery system (DDS) representing a free-standing PLLA... more
Reactive oxygen species (ROS) (H2O2, OCl−, •OH, O2−) are a family of reactive molecules that are generated intracellularly and are engaged in many biological processes. In physiological concentrations, ROS act as signaling molecules to a... more
A primary object of using mucoadhesive formulations orally would achieve a substantial increase in the length of stay of the drug in GI tract stability problem in the intestinal fluid can be improved. Mucoadhesive microsphere... more
Microwave-initiated synthesis of polyacrylamide-grafted sodium alginate, a graft copolymer with wide variety of applications has been reported in this study. The effect of reaction parameters (i.e., irradiation time and monomer... more
In the present investigation, an attempt was made to formulate floating tablets of Levofloxacin hemihydrates using with gum kondagogu, xanthum gum and HPMC K100M as release modifier. Eight batches of floating tablets of Levofloxacin... more
This study was performed to asses and establishes the prevalence of Polypharmacy in geriatric population in the Medicine ward of Rajah Muthaiya Medical College and Hospital, Annamalai University, during one year from January 2013 to... more
tSolid lipid nanoparticles (SLN) composed of long-chain fatty acids (palmitic acid, stearic acid or arachidicacid), Epikuron 200 (purified phosphatidylcholine), and bile salts (cholate, taurocholate or taurodeoxy-cholate) have been... more
Skin is most liable to have microbial or fungal infections. Emulsions are gellified emulsion in which emulsion is incorporated into gel base. Skin is having different layers like dermis, epidermis and stratum corneum and different sub... more
Bioequivalence is a word used to describe the biological equivalency of two proprietary medication preparations. When two medications are bioequivalent, it indicates they are expected to be the same. Pharmacokinetic studies are used to... more
A complete overview with focus on drug delivery
The present research was aimed to develop the meclizine hydrochloride-polyethylene glycol 20000 solid dispersions to enhance the solubility and dissolution rate. They were prepared using solvent evaporation method and... more
The present investigation concerns with the development, optimization and evaluation of an enteric coated tablets of Erythromycin stearate. Tablets were prepared by wet granulation method. Enteric coating of... more
We have not had a War on Drugs, nor has the use of drugs for pleasure been prohibited. The 1961 UN Single Convention on Narcotic Drugs imposed strict controls and punishments on particular substances while other dangerous drugs (alcohol... more
OBJECTIVES: To perform qualitative analysis of phytochemical and in-vitro antioxidant test in leaf extracts of Tradescantia spathacea. To study the in-vitro anti-cancer properties of Tradescantia spathacea extracts by MTT cell line such... more
The most emerging branch in pharmaceutical sciences known as “Pharmaceutical nanotechnology” presents new tools, opportunities and scope, which are expected to have significant applications in disease diagnostics and therapeutics.... more
This article discuses the racial disparities in the criminal justice system acknowledging the history leading to the above. The article goes over; criminalization of non-whites, 3 strikes rule, crack/cocaine sentencing, war on gangs... more
ETHICS AND EPISTEMOLOGY OF NANOTECHNOLOGY I – Critically Mapping Current Approaches From an early stage, nanoscience and nanotechnology (NST) have been associated with a political will to integrate upstream the question of their... more
Capsules are solid dosage forms in which one or more medicinal and inert ingredients are enclosed in a small shell or container usually made of gelatin. The raw materials used in the manufacture of both hard and soft gelatin capsules are... more
Introduction: Cosmeceuticals are cosmetic products with biologically active ingredients purporting to have medical or drug-like benefits. Some cosmeceuticals can act effectively when reaching their target sites in the deeper layers of the... more
This article reviews the applications of nanotechnology in the fields of medical and life sciences. Nanoparticles have shown promising applications from diagnosis to treatment of various types of diseases including cancer. In this review,... more
Rapid innovations in nanomedicine have increased the likelihood that engineered nanomaterials will eventually come in contact with humans and the environment. The advent of nanotechnology has created strong interest in many fields such as... more
Psychedelic drugs are some of the most powerful tools in the world for personal healing and psychological growth. Research at major medical centers over the past few years have shown remarkable results in the treatment of conditions such... more
The drugs of biological origins have attracted the attention of many pharmaceutical companies where it is essential to protect the heterogeneous nature and the optimal three dimensional structures of the different macromolecules. These... more