Giron-Pina, "Acute non-specific
splenitis as indicator of systemic infection.
General autopsy findings were significant for candidal bronchopneumonia and
splenitis, hepatic granulomas consistent with chronic transfusion therapy, and bilateral renal glomerulosclerosis.
(7,8) Clinical signs and lesions can include pericarditis, hepatitis,
splenitis, peritonitis, conjunctivitis, air sacculitis, rhinitis, sinusitis, anorexia, weight loss, and urate discoloration.
The remaining 17 animals showed [greater than or equal to] 1 of the following pathologic conditions: hemorrhages consistent with trauma (12/17), mild to severe intestinal coccidiosis (12/17), pneumonia (3/17),
splenitis (1/17), Taenia martis cysticerci (1/17), and external parasites (8/17).
Acute
splenitis has traditionally been thought to be suggestive of sepsis, and major pathology texts advocate this belief.
In 2 of the 6 birds (33%), a necrotic
splenitis was found, and 1 bird (17%) showed signs of immunosuppression.
The 3 remaining ducks were euthanized, and postmortem examination showed severe necrotising fibrinous enteritis, multifocal piecemeal hepatitis, and severe fibrinous multifocal
splenitis. Salmonella enterica serovar Typhimurium (phage type 9) was isolated from the ducks and was detected in at least 2 of the following from each animal: feces, spleen, bone marrow, and liver.
Histologic examination revealed a lymphohistiocytic and heterophilic
splenitis with multifocal thrombosis and necrosis, multifocal necrotizing hepatitis, and multifocal exocrine pancreas necrosis.
(5) reported outbreaks of aHEV infection and increased deaths of chickens caused by hepatitis and
splenitis and reduced egg production in chicken flocks in Hungary.
The lesions most commonly described were hepatitis (63/77),
splenitis (49/77), pneumonia (30/77), nephritis (16/77), and enteritis (12/77).
Microscopic examination showed multifocal severe necrotizing hepatitis and
splenitis associated with numerous intralesional gram-negative coccobacilli and a moderate to marked interstitial pneumonia.
