Bornyl diphosphate synthase
| geranyl-diphosphate cyclase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 5.5.1.8 | ||||||||
| CAS number | Template:CAS | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / EGO | ||||||||
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In enzymology, a bornyl diphosphate synthase (EC 5.5.1.8) is an enzyme that catalyzes the chemical reaction
- geranyl diphosphate
(+)-bornyl diphosphate
Hence, this enzyme has one substrate, geranyl diphosphate, and one product, (+)-bornyl diphosphate.
This enzyme belongs to the family of isomerases, specifically the class of intramolecular lyases. The systematic name of this enzyme class is (+)-bornyl-diphosphate lyase (decyclizing). Other names in common use include bornyl pyrophosphate synthase, bornyl pyrophosphate synthetase, (+)-bornylpyrophosphate cyclase, and geranyl-diphosphate cyclase (ambiguous). This enzyme participates in monoterpenoid biosynthesis.
Structural studies
As of late 2007, 7 structures have been solved for this class of enzymes, with PDB accession codes 1N1B, 1N1Z, 1N20, 1N21, 1N22, 1N23, and 1N24.
References
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