Cyclic-guanylate-specific phosphodiesterase

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Cyclic-guanylate-specific phosphodiesterase
Identifiers
EC number 3.1.4.52
CAS number Template:CAS
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Cyclic-guanylate-specific phosphodiesterase (EC 3.1.4.52, cyclic bis(3->5')diguanylate phosphodiesterase, c-di-GMP-specific phosphodiesterase, c-di-GMP phosphodiesterase, phosphodiesterase, phosphodiesterase A1, PDEA1, VieA) is an enzyme with systematic name cyclic bis(3->5')diguanylate 3-guanylylhydrolase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

cyclic di-3',5'-guanylate + H2O \rightleftharpoons 5'-phosphoguanylyl(3'->5')guanosine

This enzyme requires Mg2+ or Mn2+ for activity. It is inhibited by Ca2+ and Zn2+.

References

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External links

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