LW C100plus User's Manual - A4

LW C100plus
Auto Chemistry Analyzer

Operation Manual
Copyright
Shenzhen Landwind Industry Co., Ltd..All rights reserved.This manual and the information
contained herein are confidential information of Shenzhen Landwind Industry Co., Ltd.No
individual or organization is allowed to reprint,copy,modify,distribute or transmitted the
information contained in this manual without the prior wiitten permission of Shenzhen Landwind
Industry Co., Ltd.The manual is intended for users who are authorized to use such manual as a
part of the product purchased from Shenzhen Landwind Industry Co., Ltd.Use of this manual by
unauthorized personnel is strictly forbidden.
Shenzhen Landwind Industry Co., Ltd.makes no representation or warranties of any kind
concerning the document,express or implied,including but no limited to,warranties of
merchantability and fitness for for a particular purpose.Although every effort has been made to
ensure the accuracy of the information contained in this manual, Shenzhen Landwind Industry
Co., Ltd.assumes no liabilities for any errors or omissions and reserves the right to modify the
product to improve its reliablity,function or desigh without further notice. Shenzhen Landwind
Industry Co., Ltd.may modify or improve the product or program described herein at any time.
Statement
The version of this manual is A/4,the issued date is 2011-03.
Shenzhen Landwind Industry Co., Ltd. has the right to explain the manual.
Authorized EC Representative
Name: Shanghai International Trading Corp. GmbH (Hamburg)
Address: Eiffestrasse 80, 20537 Hamburg, Germany
Foreword
Foreword
Thank you for purchasing Landwinds auto chemistry analyzer.
In order to use the product correctly,please read this manual carefully. After
reading,please keep it properly for future use.
About this manual

This manual is written to help you understand the LW C100plus thoroughly about its
safety, installation,structure & functions, analysis principles, operation procedures,etc. Please
operate the system strictly as instructed by this manual.
Safty Symbols
The following table explains the safety symbols used in this manual.
Symbols
Description
This symbol means to note. What the symbol indicates may damage
your analyzer or lead to unreliable test results.
This symbol means biohazard. What the symbol indicates may cause
biological contamination.
This symbol means electric shock. What this symbol indicates may get
you electrically shocked.
This symbol means corrosion. What this symbol indicates may cause
corrosive damage.
This symbol means high temperature. What the symbol indicates may
cause personal injury.
This symbol means strong light. What the symbol indicates may hurt
your eyes.
This symbol means personal injury. What this symbol indicates may
cause personal injury.
This symbol means flammability. What this symbol indicates it is
flammable materials, which may cause fire.
Foreword
Labels
The following table explains the safety symbols used in this manual.
Labels
Description
Serial number of the product
Protective earth conductor
Manufacture date of the product

In Vitro diagnostic equipment
Alternating current
Power on
Power off
Graphics
All graphics in this manual are for illustration only and must not be used for any other
purposes.
II
Contents
Foreword .................................................................................................................................. I
Contents................................................................................................................................. III
Chapter 1 Precautions on Safety and Use ................................................................................. 1
1.1
Safety Precautions ................................................................................................. 1
1.2
Precautions on Use ................................................................................................ 2
Chapter 2 Installation ..................................................................................................................... 6
2.1
Installer ..................................................................................................................... 6
2.2
Installation Requirements ...................................................................................... 6
2.3
Connecting Purified Water Bucket ....................................................................... 7
2.4
Connecting Waste Bucket ..................................................................................... 7
2.5
Installing or Removing Reagent/Sample Disk .................................................... 7
2.6
Installing or Removing Sample Tubes ................................................................. 8
2.7
Installing or Removing Reagent Bottles .............................................................. 8
2.8
Installing or Removing Cuvettes........................................................................... 9
2.9
Installing Software .................................................................................................. 9
Chapter 3 System Structure and Functions ............................................................................. 13
3.1
Analyzing Unit ....................................................................................................... 13
3.1.1
Overall Structure ........................................................................................... 13
3.1.2
Top View......................................................................................................... 13
3.1.3
Rear View ...................................................................................................... 14
3.1.4
Left View ........................................................................................................ 14
3.1.5
Right View ...................................................................................................... 15
3.2
Functional Modules .............................................................................................. 15
3.2.1
Reagent/Sample Dispenser Assembly ...................................................... 15
3.2.2
Mixer Assembly ............................................................................................. 16
3.2.3
Auto washing System .................................................................................. 17
3.2.4
Reaction Disk ................................................................................................ 17
3.2.5
Reaction Compartment ................................................................................ 18
3.2.6
Reagent/Sample Disk .................................................................................. 18
3.2.7
Reagent Refrigerator.................................................................................... 19
3.2.8
Acid/Alkaline Wash Position........................................................................ 19
3.2.9
Optical System .............................................................................................. 20
Chapter 4 Interface and Operations .......................................................................................... 21
4.1
Screen Structure ................................................................................................... 21
4.1.1
Menu Hierarchy............................................................................................. 21
4.1.2
Shortcut Buttons ........................................................................................... 28
4.1.3
Status Buttons ............................................................................................... 29
4.1.4
Status Area .................................................................................................... 30
4.2
Software Operations ............................................................................................ 31
4.2.1
General Setting ............................................................................................. 31
4.2.2
Test Setup ...................................................................................................... 38
III
4.2.3
Statistics and Inquiry .................................................................................... 50
4.2.4
Maintenance .................................................................................................. 56
4.2.5
System Help .................................................................................................. 57
4.2.6
Calibration Request ...................................................................................... 58
4.2.7
Testing Request ............................................................................................ 59
4.2.8
Fast Mode Request ...................................................................................... 61
4.2.9
Starting Analysis............................................................................................ 62
4.2.10 Pausing Analysis........................................................................................... 63
4.2.11 Stopping Analysis ......................................................................................... 64
4.2.12 Viewing Test Results .................................................................................... 64
4.2.13 System Status ............................................................................................... 68
4.2.14 Exiting the System ........................................................................................ 68
4.2.15 Emergency Exit ............................................................................................. 68
4.2.16 Hiding/Displaying Menus ............................................................................. 69
4.2.17 Viewing Temperature Curve ........................................................................ 69
4.2.18 Sample Disk .................................................................................................. 70
4.2.19 Reagent Disk ................................................................................................. 70
4.2.20 Reaction Disk ................................................................................................ 72
4.2.21 Early Warning and Warning Messages ..................................................... 72
Chapter 5 General Operation Procedures ...................................................................................... 74
5.1
Basic Operations .................................................................................................. 74
5.2
Operation Procedure of New Item Analysis ...................................................... 77
5.3
Routine Operation Procedure ............................................................................. 78
Chapter 6 Analysis Principles and Calculation Methods ........................................................ 83
6.1
Analysis Principles ............................................................................................... 83
6.2
Analysis Procedure .............................................................................................. 83
6.2.1
Actions............................................................................................................ 83
6.2.2
Action Positions ............................................................................................ 84
6.2.3
Testing Flow................................................................................................... 84
6.2.4
Measuring Point ............................................................................................ 84
6.3
Analytical Methods ............................................................................................... 85
6.3.1
Endpoint ......................................................................................................... 85
6.3.2
Two-point ....................................................................................................... 86
6.3.3
Kinetic ............................................................................................................. 86
6.4
Absorbance and Response ................................................................................. 87
6.4.1
Absorbance ................................................................................................... 87
6.4.2
Response ....................................................................................................... 87
6.5
Calibration.............................................................................................................. 89
6.5.1
Calibration Methods ..................................................................................... 89
6.5.2
Calibration Parameters ................................................................................ 89
6.6
Concentration ........................................................................................................ 90
6.7
QC........................................................................................................................... 90
6.7.1
QC Rules ....................................................................................................... 90
6.7.2
QC Types ....................................................................................................... 91
IV
6.7.3
QC Plot ........................................................................................................... 91
6.8
Other Calculations ................................................................................................ 93
6.8.1
Calibration Curve .......................................................................................... 93
6.8.2
Substrate Depletion ...................................................................................... 94
6.8.3
Linearity Check ............................................................................................. 94
6.8.4
Prozone Check ............................................................................................. 95
6.8.5
Reaction Equilibrium Check ........................................................................ 97
6.8.6
Lamp Status Check ...................................................................................... 97
6.8.7
Cuvette Status Check .................................................................................. 97
Chapter 7 Maintenance ............................................................................................................... 98
7.1
Preparation of Tools ............................................................................................. 98
7.2
Daily Maintenance ................................................................................................ 98
7.2.1
Cleaning Panels of Analyzing Unit ............................................................. 98
7.2.2
Cleaning Sample Probe and Mixer ............................................................ 98
7.2.3
Cleaning Wash Probes and Nozzle ........................................................... 99
7.2.4
Checking Reagent/ Sample Syringe........................................................ 100
7.2.5
Checking Purified Water Tank .................................................................. 101
7.2.6
Checking Waste Tank and Tubing............................................................ 101
7.3
Weekly Maintenance .......................................................................................... 103
7.3.1
Cleaning Primary Filter of Purified Water ................................................ 103
7.3.2
Cleaning Waste Tank ................................................................................. 103
7.3.3
Cleaning Reagent/Sample Disk Refrigerator ......................................... 104
7.4
Monthly Maintenance ......................................................................................... 104
7.4.1
Cleaning Wash Pools ................................................................................. 104
7.4.2
Cleaning Reaction Compartment ............................................................. 105
7.4.3
Cleaning Rotors .......................................................................................... 106
7.5
As-Needed Maintenance ................................................................................... 106
7.5.1
Unclogging Sample Probe and Reagent Probe ..................................... 106
7.5.2
Replacing Sample Probe ........................................................................... 107
7.5.3
Replacing Mixer .......................................................................................... 108
7.5.4
Replacing Lamp .......................................................................................... 108
7.5.5
Replacing Syringe ...................................................................................... 110
7.5.6
Replacing Secondary Filter of Purified Water ........................................ 111
7.6
List of Replacement Apparatus ........................................................................ 112
7.6.1
List of replacement apparatus for User ................................................... 112
7.6.2
List of replacement apparatus for Servicing engineer........................... 112
7.7
Maintenance Log Sheets................................................................................... 112
Chapter 8 Appendices ............................................................................................................... 115
8.1
Terminology ......................................................................................................... 115
8.1.1
AD Value ...................................................................................................... 115
8.1.2
Dark Current ................................................................................................ 115
8.1.3
Water Blank ................................................................................................. 115
8.1.4
Measuring Point .......................................................................................... 115
8.1.5
Absorbance ................................................................................................. 115
8.1.6
Reaction Curve ........................................................................................... 116
8.1.7
Response ..................................................................................................... 116
8.1.8
Calibration .................................................................................................... 116
8.1.9
Calibration Curve ........................................................................................ 116
8.1.10 Calibration Parameter ................................................................................ 116
8.2
Technical Parameters ........................................................................................ 116
8.3
Transport and Storage ....................................................................................... 117
VI
Chapter 1 Precautions on Safety and Use

The following sections introduce the warning symbols used on the LW C100plus.
Ignorance of these symbols may get you into the risks of death or injury. The symbols are
listed in a random order and have the same importance.
1.1 Safety Precautions

STRONG LIGHT
1
The light transmitted by the bar code reader may hurt your eyes.
2 The light transmitted by the lamp may hurt your eyes. Do not stare at the lamp
when the system is in operation.
FLAMABILITY
1 Do not use flammable substances around the system, such as alcohol and ether.
EXPLOSION
1 Do not use explosive substances around the system.
HIGH TEMPERATURE
1
Before replacing the lamp, please switch off the Main Power and then wait at
least 30 minutes till the lamp cooling down.
Do not touch the print head or the metal part near it; otherwise you may get
burned.
ELECTRIC SHOCK
1
When the Main Power is ON, the panels, side cover or rear cover of the analyzer
are not allowed to be opened unless by qualified personnel.
Please make sure that no liquid spillage spatters on the panels. In case liquid
goes inside analyzer, just turn off the power supply and contact Landwind as soon
as possible.
PERSONAL INJURY
1
The sharp components of the analyzer can cause puncture wounds. To prevent
injury, please exercise caution when working around the reagent probe, sample
probe, mixer and steel pipe of the wash unit.
When the analyzer is in operation, do not touch such moving parts as sample
probe, reagent probe, mixer, wash unit, fan, and etc.
LW C100plus Operation Manual
BIOHAZARD
1
All test samples, such as calibrator and control, are infectious. If necessary,
please wear gloves when working with these samples.
All waste liquids should be considered infectious. Please wear gloves when
working with waste liquids.
Those components that have been attached with the reagent probe, sample
probe, mixer, wash unit, waste tubing and waste tank are infectious. Please wear
gloves when working with them.
CORROSION
1
The wash solution and certain reagents are strongly acid or alkaline. While using
them, exercise caution and prevent direct contact with your hands or clothes. In
case your hands or clothes contact the wash solution or reagents, wash them off
immediately with soap and clean water.
In case they spill into your eyes, rinse them with much water and consult an
oculist.
1.2 Precautions on Use

INTENDED USE
1
The LW C100plus is a fully-automated and computer-controlled chemistry analyzer

designed for in vitro quantitative determination of clinical chemistry parameters in
serum, plasma, urine in medical institutions.
To draw a clinical conclusion, please also refer to the patients clinical symptoms
and other test results.
OPERATOR
1
The LW C100plus is to be operated only by personnel trained and authorized by

Landwind or Landwind-authorized distributors.
ENVIRONMENT
1
Please install and operate the system in an environment specified by this manual.
Installing and operating the system in other environment may lead to unreliable
results and even equipment damage.
To relocate the system, please contact Landwind or your local distributor.
ELECTROMAGNETIC NOISE
1
Electromagnetic noise may interfere with operations of the system, or even lead to
unreliable test results and misoperation. Do not use such devices as electric drill,
mobile phones or radio transmitters near the system.
The system may generate electromagnetic wave during operation. Do not install or
use electrosensitive equipment near the system.
GROUNDING
1
Make sure the power socket is grounded correctly. Improper grounding may lead to
electric shock.
The grounding resistance must be lower than 10. Improper grounding may lead to
unreliable test results and risk o f enclosure leakage and even electric shock.
LABEL PEELS OFF

1
If any of the labels becomes blurred or peels off, please contact Landwind for
replacement.
LIQUID LEAKAGE
1
Please check the tubing connectors carefully before starting tests. Leakage may
cause inaccurate aspiration or dispensing.
Do not place reagents or samples on the panels of the analyzer; otherwise liquid
spray or leakage may occur.
PROBE BLOCKAGE
1
Check the reagents and samples carefully for insoluble matters, such as fibrin and
protein; otherwise the reagent probe or sample probe may be blocked.
WATER
1
The water used should meet the requirements of the CAP Type II water.
SYSTEM USE
1
Operate the system strictly as instructed by this manual. Inappropriate use of the
system may lead to unreliable test results or even equipment damage or personal
injury.
Before using the system for the first time, run the calibration program and QC
program to make sure the analyzer is in proper state.
Be sure to run the QC program every time you use the system, otherwise the result
may be unreliable.
Do not open the cover of the reaction disk when the analyzer is in operation
Please install the reaction disk cover,reagent/sample disk cover before start the
analyzing.
Be sure that there is no obstacle in the moving paths of the probe and mixer during
analyzing
For safety,please dont touch the reaction disk or reagent/sample disk When it is in
operation.
The operating software installed on the operation unit is specified by

Landwind.Please do not install any other software or hardware,otherwise it may
affect the system..Do not run other software when the system is in operation.
Do not use this computer for other purposes. Inappropriate use of it will probably
introduce computer virus, which may spread through floppy disks, software or
network, into the system.
SYSTEM MAINTENANCE
1
Maintain the system strictly as instructed by this manual. Inappropriate

maintenance may lead to unreliable results or equipment damage or personal
injury.
Replacement of such major parts as photometer, probe, mixing bar and syringe
plunger assembly must be followed by a calibration.
In the case that the analyzer discontinue use because of error or other reason and
needs repair or disposal,please contact Landwind,meanwhile
Please take other measures to avoid delay in results,for example,use other

machines or other methods to continue to finish the test.
Please dispose of the used cuvette in compliance with the local

regulations.Wear gloves while disposing of the used cuvette to avoid
biohazard.
Take out the reagent bottle in the analyzer and store it in accordance with the
reagent kit. for example,put the reagent back in the refrigeratory to keep it
from spoilage.
SAMPLES
1
Use serum samples that are completely separated from blood clots or urine
samples that are free from suspended matter. If fibrin exists in the serum samples
or suspended matter exists in the urine samples, the probe may be blocked.
Medicines, anticoagulants or preservative in the samples may lead to unreliable

results.
Hemolysis, jaundice or chylomicron in the samples may lead to unreliable test

results. Sample blank analysis is recommended.
Store the samples properly. Improper storage may change the compositions of the
samples and lead to unreliable results.
Sample volatilization may lead to unreliable results. Do not leave the sample open
for a long period.
The system has a specific requirement on the sample volume. Refer to this manual
for proper sample volume.
Load the sample to proper tube position on the sample disk before the analysis
begins; otherwise you will not obtain correct results.
REAGENTSCALIBRATORS and CONTROLS

1
Use proper reagents, calibrators and controls in the system.
Select appropriate reagents according to performance characteristics of the

system. Consult the reagent suppliers, Landwind or Landwind-authorized
distributor for details, if you are not sure about your reagent choice.
Store and use the reagents, calibrators and controls strictly as instructed by the
suppliers. Otherwise, you may not obtain reliable results or best performance of the
system.
If the storage of the reagents, calibrators and controls is inmproper,it may lead to
unreliable test results even if it is within the validity period.
Perform calibration after changing the reagents. Otherwise, you may not obtain
reliable results.
Contamination among reagents by carryover may lead to unreliable test results.

Consult the reagent suppliers for details.
CUVETTE USE LIFE

1
The replacement cycle for the semi-permanent cuvette is 3 months.Please replace

the cuvette accoridng to Chapter 2.9 when the cuvette is used for over 3 months.
Please use only the wash solution supplied by Landwind to wash cuvettes,
Otherwise, you may not obtain expected results.The wash solution supplied by
Landwind is WASH WI.
PARAMETERS
1
Incorrect analysis parameters may cause erroneous test results. Please consult
Landwind or your reagent supplier for correct parameters.
DATA BACKUP
1
The system can store data to the hard disk of the PC automatically. However, data
loss is still possible due to deletion or physical damage of the hard disk. We
recommends you to back up the data to portable storage device regularly.
DISPOSING OF ANALYZER
1
Some materials of the analyzer are subject to contamination regulations. Dispose

of the analyzer in accordance with your local or national guidelines for waste
disposal.
Chapter 3 System Structure and Functions
Chapter 2 Installation
2.1 Installer
The LW C100plus should be installed by Landwind or its authorized agent only. Proper
environment and proper room is needed for installation. If the analyzer needs to be
relocated, please contact Landwind or your local agent.
2.2 Installation Requirements

Item
Requirements
Installation site
The bearing ground should be level with gradient less than 1/200. It should
be hard enough to bear weight.
The installation site should be free of dust, corrosive and flammable gas, no
heat and wind source, neither mechanical vibration.
It shall not be exposed in direct sun light and should be well ventilated.
Space
Environment
Temperature
10-30
Relative
humidity
30%~85%
Atmospheric
pressure
86.0 kPa-106.0kPa
Ventilation
Well-ventilated to the outside with the analyzer not exposed directly to the
wind source.
Computer
Meeting relevant safety requirements.

CPU: above 2.0G.
Memory: above 1G.
Operating system: WIN XP/vista/win 7
Power supply
AC 100V~240V, 50Hz/60Hz, The power socket should be grounded

properly with grounding resistance below 10m.
Otherwise, please connect a copper wire with resistance below 10m to the
protective earth conductor on the rear cover of the analyzing unit and bury
the other end of the copper wire into the earth.
Electromagnetic
wave
Away from brush-type motors and electrical-contacts equipments which are

powered on and off frequently.
Water
Diameter of the particle in water shall be less than microns.

Resistivity of water shall be greater than 0.5Mcm.
The colony count shall be less than 10cfu/ml.
The dissolved silicon shall be less than 0.1mg/L.
Waste liquid
Waste liquid shall be disposed of compliantly with local regulations.
2.3 Connecting Purified Water Bucket

Operation Method:
1Put the two purified water tube that comes with the analyzer in the purified water
bucket.
2Put the Purified Water Detector Assembly in the purified water bucket and screw the
cap,and then connect the connector of the Purified Water Detector Assembly to the
connector of the purified water detector which is on the left board of the analyzer.
BIOHAZARDWear gloves and lab coat and, if necessary, goggles.

NOTEThe purified water bucket must be placed around the analyzer to ensure that
the purified water inlet tube absorb the water in the bucket.
2.4 Connecting Waste Bucket
Operation Method:
1Put the Waste Detector in the waste bucket and screw the cap,and then connect the
connecto of the Waste Liquid Outlet Tube Assembly to the waste detector which is on the
left board of the analyzer.
BIOHAZARD Wear gloves and lab coat and, if necessary, goggles.
NOTE The waste bucket should be lower than the analyzer waste liquid connector.
2.5 Installing or Removing Reagent/Sample Disk
Operation Methods
1. install reagent/sample disk,hold the handle in the center of reagent/sample disk,align

the hole below the handle to the position pin of the reagent/sample refrigerator,gently
lower the reagent/sample disk all the way down.
2. To remove reagent/sample disk,hold the handle and pull the disk upward to remove it.
Partial
Enlarged
Drawing
Position Pin
Reagent/Sample Disk
Handle
Figure 2-1 Structure of the Reagent/Sample Disk
WARNING
1
Before installing/removing reagent/sample disk,make sure that all moving parts

have been stoped,such as probe mixerreaction disk and reagent/sample disk.
BIOHAZARD
1
Wear gloves and lab coat and, if necessary, goggles.
CAUTION
1
Make sure that the cover of the reagent/sample disk is closed,otherwise cooling
effect of the refrigerator will be degraded and the sample/reagent probe may be
demaged.
The reagent/sample disk and the reagent/sample compartment may be

contaminated when being used.If samples or reagents spill on the
reagent/sampled disk or in the reagent/sample comparement,wipe them with cloth
soaked with water or disinfector after placing the Power to OFF.
2.6 Installing or Removing Sample Tubes

Operation Methods
1.To install the sample tubes,insert the sample tube into the tube holder in the
ouside-track of the reagent/sample dsik until the tube contacts the groove on the tube
rack.
2.To remove sample tubes,grab the tube and pull it upward to remove it from the tube
holder.
WARNING
1
Before installing/removing sample tubes,make sure the probe and

reagent/sample disk have been stopped. Do not use sample tubes which is
beyond the specific specification.
BIOHAZARD
1
2.7 Installing or Removing Reagent Bottles
Operation Methods
1.To install reagent bottles,insert the bottle into the bottle holder until the bottle contacts
the groove of the holder.

2.To remove the reagent bottles,grab the bottle and pull it upward to remove it from the
bottle holder.
WARNING
1
Before installing/removing reagent bottles,make sure the probe and

reagent/sample disk have been stopped. Do not use reagent bottles which is
beyond the specific specification.
BIOHAZARD
1
2.8 Installing or Removing Cuvettes
Operation Methods
1.To install cuvettes,open the reaction disk cover,grab the cuvette segment by the middle
of its buckle,slowly lower it into the cuvette holder and gently press the upper level of the
cuvette until the underneath of it completely contacts the upper level of the cuvette holder.
2.To remove cuvettes, open the reaction disk cover, grab the cuvette segment by the
middle of its buckle,pull it upward to remove it form the cuvette holder.
WARNING
1
Before installing/removing reagent bottles,make sure the probe mixer and

reagent/sample disk have been stopped.
BIOHAZARD
1
NOTE
1
Do not touch the optical surface at the lower part of the cuvette when installing
the cuvette ,otherwise it may affect the cuvettes color comparison and the
accuracy of the test result.
The optical surface should not contact the cuvette holder when installing the
cuvette,otherwise it may scratch the covette and affect the accuracy of the test
result.
2.9 Installing Software
Operation Methods
Open the software disk and click

operation software.Then the following screens appear.
to install the
If the software is installed for the first time,it needs to configure .NET Framework
4.0,see the screen below.It may take some time,please wait patiently.
Then comes out the following screen.
And then:
In the above screen,click Next.And the following screen is displayed.
10
In the above screen,you can choose the detination folder by using

buttonBrowse.And then click Next, the following screens are displayed.
the
11
And at last,shows the following screen.At this time, the software has already been
successfully installed.Click the icon in the desktop and you can start the software.
Note
1
The
v.x.x.x
shows
the
version
information
of
the
. The version is usually expressed with

numbers.
2 When installing the software,
tools folder should be in the same directory path
and
12
Chapter 3System Structure and Functions

The LW C100plus auto chemistry analyzer consists of two parts, which are the
analyzing unit and the operation unit (installed with operating software). The analyzing unit
performs automatically all the operations of tests, which include dispensing reagent 1,
dispensing sample, mixing sample, dispensing reagent 2, mixing reagent 2, measuring
absorbance, etc. The operating software drives and controls the analyzing unit to perform
all the operations.
3.1 Analyzing Unit

3.1.1 Overall Structure
Figure 3-1 Overall structure of the analyzing unit
TopTop cover
FrontFront cover
3.1.2 Top View

1
2
4
Figure 3-2Top view of the analyzing unit
1:Top cover
2Reagent/Sample dispenser assembly
3Auto cleaning system
4Mixer assembly
13
3.1.3 Rear View
Figure 3-3Rear view of the analyzing unit
1Main power protection switch 2:Main Power Input

3Fan
4. Communication Port
3.1.4 Left View
Figure 3-4Left view of the analyzing unit
1. Syringe watch window 2. Purified water detector 3.waste liquid detector

4. Purified water
5. Waste liquid
6. Waste liquid 7.Purified water
14
3.1.5 Right View
Figure 3-5Right view of the analyzing unit

1. Analyzing unit power switch
3.2 Functional Modules

3.2.1 Reagent/Sample Dispenser Assembly
Reagen/sample Probe
Figure 3-6Probe dispenser assembly
a. Functions
Specified amount of reagent/sample is aspirated from the sample tube/reagent
bottle and then dispensed into a reaction cuvette.
b. Specifications
Reagent: 10450L, with increment of 1L
Sample: 2-45L, with increment of o.1L
c. Actions
The probe moves up and down at the following positions in the order presented
15
below.
Reagent bottle
Cuvette
Wash pool
Sample tube
Cuvette
Wash pool
d. Fluid path diagram
3.2.2 Mixer Assembly
Mixer
Figure 3-7Mixer assembly
a. Functions
The mixer assembly stirs the reaction mixture in the cuvettes.
b. Actions
The mixer moves up and down, rotates at the following positions in the order presented
below.
16
3.2.3 Auto washing System
Wash Probe
Figure 3-8Auto Washing System
a. Functions
Wash cuvettes automatically.
b. Actions
The wash probe moves up and down,finishes the actions of draining the reaction liquid
and filling in the water.
3.2.4 Reaction Disk
Figure 3-9Structure of the reaction disk
a. Functions
The reaction disk holds cuvettes, in which the sample and reagent react at a constant
temperature of 37 and then measured directly by colorimetry.
b. Specifications
Cuvettes: 81
Light path: 5mm
Cuvette material: Special semi-permanent plastic
c. Actions
17
The reaction disk always rotates clockwise.
3.2.5 Reaction Compartment
Figure 3-10Structure of the reaction compartment
a. Functions
The reaction compartment provides an environment of constant temperature 37 for
the reaction mixture.
b. Specifications
Set temperature: 37
Fluctuation: 0.1
3.2.6 Reagent/Sample Disk
Figure 3-11Structure of the reagent/sample disk
a. Functions
The sample disk holds reagent bottles/sample tubes, and rotates to carry each of
them to the specified position for reagent/sample aspirating.
b. Specifications
Round disk, with three circles, hold 40 sample positions, and 40 reagent positions.
The sample disk holds different kinds of sample tubes as below:
Minimal sample tube 1237mm1425mm
Blood collection tube1268.5 mm1299 mm12.775 mm12.7100 mm,
13 X 75 mm13 X 95 mm13 X 100 mm;
Plastic tube
1268.5 mm1299 mm12.775 mm12.7100 mm,
13X 75 mm13 X 95 mm13 X 100 mm.
Reagent bottles:40ml for the inside-track of the reagent disk and 20ml for the
outside-track. They are compatible with reagent bottles of Hitachi 7170.
18
NOTE
(1) The No.39 reagent position is specified for the wash solution only. Please use only
the wash solution supplied by Landwind to wash cuvettes, Otherwise, you may not
obtain expected results.
(2) The wash solution supplied by Landwind is WASH WI.
c. Actions
The reagent/sample disk rotates clockwise or anticlockwise.
3.2.7 Reagent Refrigerator
Figure 3-12: Structure of the reagent refrigerator
a. Functions
The reagent refrigerator holds the reagent disk and the sample disk and provides a
refrigerated environment for the reagents.
b. Specifications
The reagent refrigerator keeps all reagents at the temperature of 4-12.
3.2.8 Acid/Alkaline Wash Position
a. Functions
The acid/alkaline wash position is for acid/alkaline wash solution which is used to
wash probe and mixer.
19
b. Specifications
specified position, 60ml.
NOTE
Landwind recommends you to use the following acid/alkaline wash solution:
1acid wash solution0.1mol/L HCl
2alkaline wash solution: sodium hypochlorite solution containing 0.5% active
chlorine
NOTE
Landwind recommends you to use the acid/alkaline wash solution alternately,eg:use
the acid wash solution one day ,and use the alkaline wash solution the next day.
NOTE
Please use the acid/alkaline wash solution recommended by Landwind, Otherwise,
you may not obtain expected results.
3.2.9 Optical System

a. Functions
The photometer measures the absorbance of the reaction liquid in the cuvette while
the reaction disk is rotating.
b. Specifications
Wavelength: 340nm-670nm, 8 wavelengths in total.
Number of wavelengths used simultaneously: 1 or 2 wavelengths.
Accuracy of wavelength: 2nm.
Half-wave width: < 12nm.
Detector: Photodiode array.
Light source: Tungsten-halogen lamp, 12V 20W.
c. Photometric measurement flow
20
Chapter 4 Interface and Operations

4.1 Screen Structure
The user interface of the LW C100pluss operating software includes menus, shortcut buttons,
status area and status button.. See the figure below.
The main menu includes General Setting, Test Setting, Stat./Search, Maintenance and System
Help.
The shortcut buttons include Calibration Request, Testing Request, Fast Mode Request, Start,
Pause, Stop, Results, Exit, Emergency Exit, Hide/Display Menu, Temp. Curve, Sample Disk, Reagent
Disk, Reaction Disk and Warning Messages.
The status buttons include:temperature,lamp status, status of purified water, status of waste
liquid,running status(in testing,standby and test forbidden,indicated with different color and rotation
status),operator and system date & time.
4.1.1 Menu Hierarchy

The following tables show the hierarchical structure of the menus of the LW C100plus operating
21
software.
First-level
Menu
Second-level
Menus
Third-level
Menus
Hospital
Basic Info
Hospital
Setting
Department
Basic Info
General
Setting
Doctor Basic
Info
Function
Buttons
Modify
Click to edit the basic information of

the current hospital.
Save
Click to save your input or

modifications
to
the
hospital
information.
Cancel
Click to cancel your input or

modifications
to
the
hospital
information.
Return
Click to return to the main screen.
Add
Click to add a department record.
Delete
Click to delete
department.
the
selected
Modify
Click
to
edit
department.
the
selected
Save
Click to save your input or changes

to the current department.
Cancel

changes to the current department.
Return
Add
Click to add a doctor record.
Delete
Click to delete the selected doctor.
Modify
Click to edit the selected doctor.
Save

to the current doctor.
Cancel
Click to cancel your input

changes to the current doctor.
Return
>>
User Authority
Management
User
Management
User
Description
or
Click to move to the next user.
<<
Click to move to the previous user.
Search
Click to search certain user based

on the conditions you have set.
Add
Click to add a user.
Delete
Click to delete the current user.
Modify
Click to Edit the current user

information.
Save

to the current user.
Cancel

changes to the current user.
Return
>>
or
Click to move to the next user.

22
Authority
Setting
Change
Password
Login
Another
Account
by
Item Printing
Order
Item Unit
First-level
Menu
Test Setting
Second-level
Menus
Item
Parameter
Third-level
Menus
<<
Click to move to the previous user.
Search
Click to search certain user based

on the conditions you have set.
Save
Click to save your changes.
Cancel
Click to cancel your changes.
Return
OK
Click to save your changes to the

password.
Return
OK
Click to log in the system by another

user account.
Return
Move
Forward
Click to move the selected item to

the previous position.
Move
Backward
Click to move the selected item to

the next position.
OK
Click to save your changes to the

printing order.
Cancel
Click to cancel your changes.
Add
Click to add an item unit.
Delete
Click to delete the selected item

unit.
Modify
Click to Edit the current item unit.
Save

to the current item unit.
Cancel

changes to the current item unit.
Return
Function
Buttons
Description
Add
Click to add an item.
Delete
Click to delete the selected item.
Modify
Click to Edit the current item.
Save

to the current item.
Cancel

changes to the current item.
Template
Click to set up printing template.
Preview
Click to preview the test report.
Print
Click to print the test report.
Return
or
23
Calibration
Setting
Add
Click to add a calibrator and set its

position on the calibrator disk and its
concentration for each item.
Delete
Click to delete
calibrator
and
information.
Modify
Click to change various information

of the current calibrator, such as
name, position, concentration for
each item, etc.
Save

to the current calibrator.
Cancel

changes to the current calibrator.
Return
Add
Click to add a control, and set up its

name, target value for each item,
standard deviation (SD), cumulative
sum check rule, etc.
Delete
Click to delete the selected control

and its affiliated information.
Modify
Click to change various information

of the current control, such as name,
target value for each item, SD,
cumulative sum check rule, etc.
Save

to the current control.
Cancel

changes to the current control.
Return
Add
Click to add a calculation test, and

set the abbreviation of Item name,
full name, result unit, number of
decimals,
reference
range,
calculation formula, etc.
Delete
Click to delete the selected

calculation test and its affiliated
information.
Modify
Click to Edit the relevant information

of the current calculation test,
including the abbreviation of Item
name, full name, result unit, number
of decimals, reference range and
calculation formula.
QC Setting
Test Setting
Calculation
Test
the
its
selected
affiliated
or
24
Save

to the current calculation test.
Cancel

changes to the current calculation
test.
Return
Add
Click to add a profile, and set the

abbreviation of Item name, full name
and items of the profile.
Delete
Click to delete the selected profile

and its affiliated information.
Modify
Click to Edit the relevant information

of the current profile, including the
abbreviation of Item name, full name
and items of the profile.
Save

to the current profile.
Cancel

changes to the current profile.
Return
Setting
Click to set up or Edit the carryover

properties of the reagent probe for
different reagents.
Save
Click to save your settings or

modifications.
Cancel
Click to cancel your settings or

modifications.
Delete
Click to delete your settings.
Return
Modify
Click to edit Multiple or Original

Volume for different automatic
dilution conditions.
Save
Click to save your settings or

modifications.
Cancel
Click to cancel your settings or

modifications.
Return
Profile
Carryover
Probe
Carryover
Dilution
Parameter
First-level
Menu
Stat./Search
Second-level
Menus
History Result
Search
Third-level
Menus
Function
Buttons
or
Description
Search
Click to search for desired data

according to the set conditions.
Reaction
Curve
Click to view the reaction curve of

the selected test.
25
QC
Result
Search
Calibration
Search
Modify
Click to modify the relevant

information of the current history
data, including patient name,
gender, age, register No., admission
No., sending department, bed No.,
etc.
Template
Click to select a printing template for

the history data.
Preview
Click to preview the current history

data.
Print
Click to print the current history

data.
Distributing
Chart
Click to view the distribution of the

sample results for certain test,
including the maximum, minimum,
mean value and SD.
Return
Search
Click to search for desired QC data

according to the set conditions.
QC Result
Detailed
Click to view the detailed QC results

of the selected control.
Return
Search
Click to search for desired

calibration data according to the set
conditions.
Set It as
Current
Click to set the selected calibration

result as the current standard.
Details
Click to view the detailed information

of the current calibration result,
including calibrator name, reaction
curve, etc.
Return
Search
Click to search for desired reagent

blank data according to the set
conditions.
Return
Search
Click to search for desired cuvette

blank data according to the set
conditions.
Return
Search
Click to view the

workload according
conditions.
Reagent
Blank Search
Cuvette Blank
Search
Workload
Stat.
statistics of
to the set
26
First-level
Menu
Second-level
Menus
Template
Click to set up a printing template for

statistical workload data.
Preview
Click to preview the statistical report.
Print
Click to print the statistical report.
Return
Third-level
Menus
Function
Buttons
Send
Click to execute the selected

instruction.
Return
Send

instruction.
Return
Send

instruction.
Return
Send

instruction.
Return
Send

instruction.
Return
Send

instruction.
Return
OK
Click to start to wash the cuvette
Cancel
Yes
Click to execute the instruction of

clearing uncompleted requests.
No
Click to return to the main screen

without executing the instruction.
Yes
Click to execute the instruction of

saving the analysis data to the
history database.
No

without executing the instruction.
Search
Click to search for desired error

logs according to the set
conditions.
Delete
Current
Error Info
Click to delete the current error

log.
Clear All
Errors Info
Click to delete all errors logs.
Main Unit
Sample Unit
Mixer Unit
Maintenance
Reaction
Disk
Photometric Unit
Sample/Reagent
Disk Unit
Temperature
Unit
Maintenance
Wash Cuvette
Clear
Uncompleted
Request
Save
Analyzing
Data
History
to
Analyzer
Running Error
Log
Description
27
Lamp
changing
Initialization
First-level
Menu
Second-level
Menus
Third-level
Menus
Return
Yes
Click to initialize after replacing

the lamp.
No
Function
Buttons
Description
Help File
System Help
Click to view the help manual.
Version
Information
OK
4.1.2 Shortcut Buttons

Buttons
Calibration
Testing
Second-level
Menus
Function
Buttons
Request
Click to save the calibration requests.
Calibration
Request List
Click to view the list of requested

items.
Calibrator Setting
Click to add, Edit or delete a

calibrator.
Return
Request
Click to save the testing requests.
Return
Request
Click to
requests.
Return
OK
Click to start the analysis.
Cancel

without starting the analysis.
Continue
Click to pause the current test that

has not been adding R1.
Cancel

without pausing the test.
OK
Click to stop the current testing.
Cancel

without stopping the analysis.
Reaction Curve
Click to view the reaction curve of the

selected test.
Template
Click to set up the printing template.
Preview
Click to preview the test report.
Print
Click to print the test report.
Return
OK
Click to exit the system following the

standard procedure.
Fast
Start
Pause
Stop
Results
Exit
Description
save
the
fast
testing
28
Emergently
Cancel
Click to cancel exiting and return to

the main screen.
OK
Click to exit the system following the

emergency exiting procedure.
Cancel
Click to cancel exiting and return to

the main screen.
Hide Menu
Temperature
Curve
Click to hide or show the main menu.

Return
Details
Click to the view the details of

temperature.
Reaction Curve

selected test.
Return
Reagent Volume
Check
Click to check the residual reagent of

the selected item.
Refresh Reagent
Volume
New reagent volume will be displayed

only after the residual check is
performed.
Cancel Reagent
Position
Click to release the reagent position

of the selected item.
Template
Click to set up the printing template.
Preview
Click to preview the reagent report.
Print
Click to print the list of reagent

position.
Return
Reaction Curve

selected test.
Return
Delete
the
Current Warning
Click to delete the selected prevent

warning message.
Delete
Warning
Click to delete all prevent warning

messages.
Sample Disk
Reagent Disk
Reaction Disk
Early warning
Warning
Messages
All
Return
Delete
the
Current Warning
Click to delete the selected warning

message.
Delete
Warning
Click to delete all warning messages.
Return
All
4.1.3 Status Buttons

Status Buttons
Description
Indicates that the system is in standby mode.
29
Indicates that the system is performing routine tests. The icon is

rotating.
Indicates that the system is performing fast tests. The icon is
rotating.
Indicates that testing is complete.
Indicates that communication with the main unit fails and testing is
forbidden.
Indicates that the lamp intensity is heavily weak.
Indicates that the lamp intensity is weak.
Indicates that the lamp intensity is normal.
Indicates that the distilled water tank has run out of water. The icon is
dynamic.
Indicates that the level of distilled water is normal.
4.1.4 Status Area

Status Area
Description
Indicates the current temperature of the reaction disk.
Indicates the current operator.
Indicates the current system date and time.
30
4.2 Software Operations

4.2.1 General Setting
General settings cover hospital information setup, user authority management, password
maintenance, log-in with another account, item printing order setup, item unit setup, etc. The following
sections introduce the settings in detail.
4.2.1.1 Hospital Setting

In the Hospital Setting window you can set up the basic information of hospital, departments and
doctors.
Setting up hospital information
1. Explanation of fields
Field
Description
Operation
hospital name
Name of the hospital
Enter it in the edit box.
hospital principal
Contact
hospital.
hospital address
Area of the hospital.
Tel
Telephone number of the

hospital.
Website
Website of the hospital.
Population
Population of the hospital.
Total Dept. number
Number of departments in the

hospital.
Remark
Comments and notes about

the hospital.
Enter them in the edit

box.
person
of
the
2. General operation procedure

Editing hospital information
1
Click the Edit button.
31
Enter the hospital information in corresponding edit boxes.
To save the information you have entered, click Save; otherwise, click
Cancel.
Setting up department information
Field
Description
Operation
Serial No
Sequence number
department.
of
Name
Name of the department.
Principal
Contact person
department.
the
Population
Population of the department.
Tel

department.
Remark

the department.
of
the


Adding a department
1
Click the Add button.
Enter the department information in corresponding edit boxes.
Click Save to save your settings.
Editing department information

1
Select a department you want to Edit from the Department Details List.
Enter the department information in corresponding edit boxes.
32
Cancel.
Deleting a department
Select a department you want to delete from the Department Details

List.
Click the Delete button.
To delete the department, click Yes; otherwise, click No.
Setting up doctor information
Field
Description
Operation
Department
Select a department of which

you want to edit the doctor
information.
Select it from the

pull-down list box.
Number
Sequence
doctor.
Name
Name of the doctor.
Position
Position of the doctor.
Tel

doctor.
Email
Email address of the doctor.
Add.
Address of the doctor.
Remark

the doctor.
Enter them in the edit

box.
number
of
the

Adding a doctor
33
Select a department from the pull-down list box for which you want to
add a doctor.
Enter the doctor information in corresponding edit boxes.
Editing doctor information

1
Select a department from the pull-down list box.
Select a doctor you want to Edit from the Doctor Details List.
Enter the doctor information in corresponding edit boxes.
Cancel.
Deleting a doctor
1
Select a department from the pull-down list box.
Select a doctor you want to delete from the Doctor Details List.
To delete the doctor, click Yes; otherwise, click No.
4.2.1.2 User Authority Management

In the User Management window, you can manage all users and assign necessary authority to
them.
User management
Field
Description
Operation
Login Name
User name used to log in the

system.
Name
Name of the user.
Company
Name of the company to

which the user is dedicated.
Tel

user.
34
Field
Description
Operation
Password
Password used to log in the

system.
Confirm Password
Password entered to confirm

the previous one.
Remark

the user.

Adding a user
1
Enter the user information in corresponding edit boxes.
Editing user information

1
Select a user you want to Edit by using the >> or << button.
Enter the user information in corresponding edit boxes.
Cancel.
Deleting a user
Select a user you want to delete by using the >> or << button.
To delete the user, click Yes; otherwise, click No.
User authority setting
35
Field
Description
Operation
Login
Name
User name used to

log in the system.
Click >> or << to select the desired user

name.
Name
Name of the user.
Click >> or << to select the desired user

name.

Setting up user authority
1
Select a user you want to set authority by using the >> or << button.
Set up operation authority for the selected user on the General Setting
Group tab page.
Proceed to other tabs and set corresponding operation authority.
To save your settings, click Save; otherwise, click Cancel.
4.2.1.3 Password Maintenance
Field
Description
Operation
User Name
User name used to log in the

system.
Select a user name from the

pull-down list box.
Original
password
Old password used to log in

the system.
New
password
New password of the user to

log in the system.
Confirm New
password
Password entered to confirm

the previous new one.

Changing password
1
Select a user name you want to change password from the pull-down
list box.
Enter the old password in the Original Password field.
Enter your new password in the New Password field.
Enter your new password again in the Confirm New Password field.
To save your new password, click Save; otherwise, click Cancel.
36
4.2.1.4 Login by Another Account
General operation procedure

Logging in with another account
1
Select a user name from the pull-down list box.
Enter the password.
Click OK to log in the system, or click Cancel to abort.
4.2.1.5 Test result printing order adjusting
Field
Description
Serial
number
item number.
Item
Abbreviation of the item.

Adjusting the print order of Item
1
Choose the item being moved in Item field.
Click the move forward button to move the Item ahead, Click the move
backward button to move the Item back.
37
Click OK to save your adjusting, and the print order of results will follow
the adjusted order.
Click cancel to abandon your adjusting.
4.2.1.6 Item Unit Setup
Field
Description
Operation
Unit Name
Name of item unit.
Remark
Comments or notes about the

unit.
Enter them in the edit box.

Adding a unit
1
Enter the unit information in corresponding edit boxes.
Editing a unit
1
Select a unit you want to Edit from the Item Unit List.
Enter the unit information in corresponding edit boxes.
Deleting a unit
1
Select a unit you want to delete from the Item Unit List.
To delete the unit, click Yes; otherwise, click No.
4.2.2 Test Setup

By using testing setting, you are allowed to set up item parameters, calibration, quality control,
calculation items, profiles and carryover.
38
4.2.2.1 Item Parameter Setup
Field
Description
Item Number
Sequence number of the item
Operation
Generated by the system automatically and
cannot be changed.
Abbreviation
Abbreviation of the item.
Full Name
Full name of the item.
Decimal Digits
Number of decimals in the test

result.
Select 0, 1, 2 or 3 from the pull-down list box.
Result Unit
Unit of the result.
Select it from the pull-down list box.
Test
Setting
Online setup of item units.
Click to enter the test unit setting window.
Price
Cost price for a single test of

the current item.The default
value is 0.
Testing
Method
Testing method of the current

item.
Select it from the pull-down list box. The options

include endpoint, two-point and Kinetic.
Direction
Changing direction of the

absorbance during the reaction
process.

include ascending and descending.
Pri. Wave.
Primary wavelength used for

testing.

include 340, 405, 450, 510, 546, 578, 630 and
670.
Secon. Wave.
Secondary wavelength used

for testing.
Select it from the remaining wavelength in the

pull-down list box.
Sample
Volume
Amount of sample dispensed

for normal analysis. The unit is
l.
Enter it in the edit box. It should be within 2 to 48

at the increment of 0.1.
Unit
39
Field
Description
Amount
of
reagent
1
dispensed for testing. The unit
is l.
Operation
Enter it in the edit box. It should be within 150 to
480ul at the increment of 1ul.
R2
Amount
of
reagent
2
dispensed for testing. The unit
is l.
Enter it in the edit box. It should be within 10 to

300ul at the increment of 1ul.
Reac. begin
end segment
The
Start/end
measuring
points for result calculation.
Enter them in the edit boxes. Enter L in the left

edit box and enter M in the right one.
R1
The L and M you have entered should meet the

following requirements:
1. Single-reagent endpoint analysis:
1L10M49
2. Double-reagent endpoint analysis:
10L19M49
3. Single-reagent two-point and Kinetic analysis:
10LM49
4. Double-reagent
analysis:
two-point
and
Kinetic
19LM49
Samp. Blank
segment
The
Start/end
measuring
points for Blank Response.
This is only applied to double-reagent two-point

and Kinetic analysis.
Enter them in the edit boxes. Enter X in the left
edit box and enter Y in the right one.
The X and Y you have entered should meet the
following requirements:
1. Double-reagent two-point
analysis: 10XY18
of
and
Kinetic
Calibration
Method
Calibration method
current item.
the

include
Linear,
Logit-4P,
Logit-5P,
Exponentional-5P, Polynominal-5P, Spline and
Factor. When selecting Factor, you need to
enter a specific value in the edit box next to this
field. For more detail,please refer to chaper 6.5.
Set
Calibration
Curve
Parameter
This button will appear when a

calibration method rather than
Factor is selected. Click this
button to set up various
parameters
of
calibration
curve.
Click this button. The following window is

displayed.
40
Field
Description
Operation
Enter specific values in corresponding edit
boxes. For more detail,please refer to chapter
6.8.1.
The test result can be

calibrated with the equation of
y=ax+b. Where, x is the actual
result; y is the calibrated result;
a is the slope; and b is the
intercept.
Enter a number in the edit box. The default is 1.
Reac Curve
Linearity Limit
Used to judge the linearity of

the reaction curve.
Enter an integer within 0~100. For more

detail,please refer to chapter 6.8.3.
Substrate
Limit
Used to judge whether the

substrate is exhausted during
reaction. It is an absorbance
value multiplied by 10000.
Enter an integer within 0~40000. For more

detail,please refer to chapter 6.8.2.
Prozone
Check
Used
to
enable/disable
prozone check, and set up the
start/end points and limit for
prozone check.
Select the radio box to enable prozone check.
Slope a
Intercept b
Prozone
check
is
only
available for endpoint analysis.
Enter a number in the edit box. The default is 0.
The following boxes are activated. The first one

is the start point N; the second one is the end
point P; and the third one is the check limit PC
(prozone check). The start/end points N, P and
the reaction time L, M should meet the following
requirements.
Single-reagent endpoint analysis: 1L10N
PM49
Double-reagent endpoint analysis:
10L19NPM49
PC should be an integer within 0-100.
For more detail,please refer to chapter 6.8.4
Reference
Range
Enter the default reference

range of test result.
Enter the upper and lower limits in the two edit

boxes.
Details
Click this button to set up

reference ranges for patients
of different genders and ages
and for different sample types.

displayed.
41
Field
Description
Operation
Adding a reference range
1. Select gender and sample type from the
corresponding pull-down list boxes.
2. Click Add. Enter the upper/lower limits of age
and reference range.
3. Click Save to save your settings.
Editing reference range
1. Select a reference range you want to Edit
from the Reference Range Details List
Area.
2. Click Edit. Enter the new upper/lower limits of
age and reference range.
Deleting a reference range
1. Select a reference range you want to delete
from the Reference Range Details List
Area.
2. Click the Delete button.
3. Click Yes.
Linearity
Range
Please refer to the reagent kit

instruction for the input items
linearity range.

boxes.
Response
Range
The
response
range
corresponding to the linearity
range of the input item. It is an
absorbance value multiplied by
10000.

boxes. The values should be within
-40000~40000.
R1
Absorbance
Range
Normal range of absorbance

for reagent 1. It is an
10000.

-40000~40000.
Working
Liquid
Absorbance
Range
Normal range of absorbance

for the reaction mixture. It is an
10000.

-40000~40000.

Adding an item
1
Enter the item information in corresponding edit boxes.
Editing item parameters

1
Select an item you want to Edit in the item list.

42
Enter the item information in corresponding edit boxes.

To save your changes, click Save; otherwise, click Cancel.
Deleting an item
1
Select an item you want to delete in the item list.
To delete the item, click Yes; otherwise, click No.
4.2.2.2 Calibration Setup
Field
Description
Calibrator
Name of the calibrator.
Name
Operation
Calibration
Disk Pos
Position of the calibrator on the

calibrator disk.
Set it by clicking a position on the calibrator

disk on the left of the window.
Item
Conc.
Setting
Display Area
Concentration of the calibrator

for various items.
Enter them in the edit boxes.

Adding a calibrator
1
Enter the calibrator information in corresponding edit boxes.
Editing calibrator information

1
Select a calibrator you want to Edit in the Calibrator Display Area.
43
Enter new calibrator information in corresponding edit boxes. If you want to relocate the
calibrator, click a new position on the sample disk graph, and then click Save. Please
note the new position you should be empty.
Deleting a calibrator
1
Select a calibrator you want to delete in the Calibrator Display Area.
Click Yes to delete the selected calibrator; or click No to abort.
4.2.2.3 QC Setup
Field
Control Name
Description
Name of the control.
Operation
Target Value
Target value of the control

for various items.
SD
Standard deviation of the

control for various items.
Cumulative sum check rule

of the control for various
items.
Cum.
Check
Sum
For more detail about QC rule,please refer to chapter 6.7.1

Adding a control
1
Enter the control information in corresponding edit boxes or select an option from the
pull-down list boxes.
44
Editing control information

1
Select a control you want to Edit in the Control Display Area.
Enter the control information in corresponding edit boxes or select an option from the
pull-down list boxes.
Deleting a control
1
Select a control you want to delete in the Control Display Area.
Click Yes to delete the selected control; or click No to abort.
4.2.2.4 Calculation Test Setup
Field
Description
Abbr.
Abbreviation of the calculation
test.
Operation
Full Name
Full name of the calculation

test.
Result Unit
Unit of the calculation test

result.
Select it from the pull-down list box. It can

also be left blank.
Decimal Digits
Number of decimals in the

calculation test result.
Select 0, 1, 2 or 3 from the pull-down list

box.
Reference
Range
Enter the default reference

range of test result.
Enter the upper and lower limits in the two

edit boxes.
Details
Click this button to set up

reference ranges for patients

displayed.
45
Field
Description
of different genders and ages
and for different sample types.
Operation
Adding a reference range

1. Select gender and sample type from the
corresponding pull-down list boxes.
2. Click Add. Enter the upper/lower limits of
age and reference range.
Editing reference range
1. Select a reference range you want to Edit
from the Reference Range Details List Area.
2. Click Edit. Enter the new upper/lower
limits of age and reference range.
Deleting a reference range
1. Select a reference range you want to
delete from the Reference Range Details
List Area.
2. Click the Delete button.
3. Click Yes to delete the selected reference
range; or click No to abort.

Adding a calculation test
1
Enter the calculation test information in corresponding edit boxes or select an option
from the pull-down list boxes.
Enter the calculation formula by selecting items in the Item Display Area and selecting
values and operators in the Boolean Calculation Button Display Area.

46
Editing calculation test information

1
Select a calculation test you want to Edit in the Calculation Test Parameter block.
Enter the calculation test information in corresponding edit boxes or select an option
from the pull-down list boxes.
To Edit the calculation formula, click the Rebuild Formula button and set the formula
again.
Deleting a calculation test

1
Select a calculation test you want to delete in the Calculation Test Parameter block.
To delete the calculation test, click Yes; otherwise, click No.
4.2.2.5 Profile Setup
Field
Description
Profile No.
Sequence number of
profile
the
Operation
Generated by the system automatically and
cannot be changed.
Abbr.
Abbreviation of the profile.
Full Name
Full name of the Profile.

Adding a profile
1
Enter the profile information in corresponding edit boxes and select items in the item
display area. Clicking once means to select the item, and clicking again means to
deselect it.
47
Editing profile information

1
Select a profile you want to Edit in the Profile List Area.
Enter new profile information in corresponding edit boxes and select or deselect items
in the item display area.
Deleting a profile
1
Select a profile you want to delete in the Profile List Area.
To delete the profile, click Yes; otherwise, click No.
4.2.2.6 Carryover Setup

The reagent probe may get contaminated after aspirating or dispensing different reagents. The LW
C100plus provides a function that enables you to minimize the carryover effect by separating the items
whose reagents may contaminate each other.

Setting up carryover between adjacent reagents
1
Click the Setting button.
Select a reagent in the Current Reagents List Display Area. It may be R1 or R2 for a
double-reagent item. Clicking once means to select the item, and clicking again means
to deselect it.
Select one or more reagents in the Reagents That May be Affected List Display Area. It
may be R1 or R2 for a double-reagent item. Clicking once means to select the item,
and clicking again means to deselect it.

48
Editing carryover settings

1
Click the Setting button.
Select a reagent you want to Edit in the Current Reagents List Display Area. It may be
R1 or R2 for a double-reagent item. Clicking once means to select the item, and
clicking again means to deselect it.
Select one or more reagents in the Reagents That May be Affected List Display Area. It
may be R1 or R2 for a double-reagent item. Clicking once means to select the item,
and clicking again means to deselect it.
Deleting carryover settings

1
Select a carryover setting you want to delete in the Carryover Reagents Info List
Display Area.
Click Yes to delete the selected carryover setting; or click No to abort.
4.2.2.7 Dilution Parameter
Field
Description
Automatic
The conditions for
dilution
automatic dilution
conditions
Operation
Select it from the pull-down list box.Including
substrate depletion,above linear range upper limit and
antigen excess.
Multiple
Dilution ratio
Follow the software instruction.It ranges from 2.5 to

100.
Original
Volume
The original sample

volume
Follow the software instruction.It ranges from 2 to

100ul.
2General operation procedure

Modify
1
In the auto-dilution list area,select the one you want to modify;
Click the button modify
Enter auto-dilution information in corresponding edit boxes

49
4.2.3 Statistics and Inquiry

In the Routine Sample Test Result History Search window, you can search for desired history
results, QC data, calibration data, reagent blank data and cuvette blank data, and view statistics of
workload.
4.2.3.1 History Result Inquiry

Searching for history data
Select History Result Search in the Stat./Search menu.
Set up the conditions and click Search. The qualified results are displayed in the Search
Result Display list.
Click Export to export the search result.
50
4.2.3.2 QC Result Inquiry
Perform the following steps to search for the QC records of an item.

1
Select a QC type in the Select QC Type block. There are three QC types in total, which
include Real Time QC, Daily QC and Day-to-Day QC.
2
Set the start date and end date and an item for inquiry.
3
Click the Search button. The Control Display Area shows all the controls used by the
item, and the QC Status Display Area shows the QC status of the item.
Click QC Result Detailed. All controls of the item and the QC results during the set period
are displayed.
Click Multi-rule Plot, Cumulative Sum Check and Twin Plot successively. The
corresponding QC plot of the item during the set period is displayed.
Click Print to print the QC plot and QC test results.
Click Print Curve to Printer to print corresponding QC plot.
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4.2.3.3 Calibration Inquiry

Inquiring calibration records of an item
1
Set the start and end date for inquiry in the Calibration Date block.
Select an item in the Search Item Selection Area. Clicking once means to select the
item, and clicking again means to deselect it.
Click the Search button. All qualified calibration records are displayed in the Search
Result Display Area in the right part of the window.
If you want to view the details of a calibration record, select it in the Search Result
Display Area.
Click Details. A new window pops up, displaying the detailed data of the selected
calibration record.
To print a calibration record, select it and then click Print.
If you want to set a calibration record as the current one, select it and then click Set It
as Current. The record will be used for calculating concentration of the following
samples of the item.
52
4.2.3.4 Reagent Blank Inquiry

Inquiring reagent blank records of an item
1
Set the start and end date for inquiry in the Search Time Phase block.
Select an item in the Search Item Selection Area. Clicking once means to select the
Click the Search button. All qualified reagent blank records are displayed in the Search
Result Display Area in the upper-right part of the window. In the Reagent Blank Search
Distributing Chart Display Area, the trend of reagent blank is illustrated with each dot
indicating a reagent blank test.
If you want to view the details of a reagent blank record, select it in the Search Result
Display Area.
53
Click Reaction Curve. The following window pops up, displaying the reaction curve of
the reagent blank test.
Click Data Details >> to view the absorbance of each measuring point.
6
To print the details of the selected reagent blank record, click Plot Print.
4.2.3.5 Cuvette Blank Inquiry

Inquiring cuvette blank records
1
Set the start and end date for inquiry in the Search Time Phase block.
Select a cuvette No. by clicking a cuvette position on the reaction disk graph.
54
Click the Search button. All qualified cuvette blank records are displayed in the Search
Result Display Area in the upper-right part of the window. In the Cuvette Blank Search
Distributing Chart Display Area, the trend of cuvette blank is illustrated with each dot
indicating a cuvette blank test.
4.2.3.6 Workload Statistics
Field
Description
Operator
The operator who is
summarize the workload.
going
to
Operation
Sample Type
Sample type for workload statistics.
Time
Start and end date for statistics.
Select it from the pull-down list box

or enter it with the keyboard.
All Tests
Selecting it means to summarize the

tests of all items.
Clicking once means to select the

item, and clicking again means to
deselect it.

Workload statistics
1
Select an operator and sample type from the pull-down list box.
Select or enter the start and end date for statistics.
If you want to include all items, click the All Tests radio box; otherwise, select an item in
the Search Item Selection Area.
Click Search.
All qualified results are displayed in the Display Search Result area.
55
4.2.4 Maintenance
The LW C100plus provides you with a maintenance function, which enables you to wash
cuvettes,clear unfinished requests, save sample results in the history database, perform cuvette blank
and inquire error logs The following sections introduce the maintenance operations in detail.
4.2.4.1 Wash Cuvette

When the analyzer is used for a period of time,you need to take the initiative to wash the
cuvettes.At this time,you can perform the function.Click on the menu,a pop- up menu will be displayed
as shown in the figure below
Click Ok to start to wash cuvettes automatically.,or click Cancel to return to the main screen.
Note
1 The replacement cycle of the semi-permanent cuvette is 3 months.After
using the cuvtte for over 3 months,please replace the cuvettes according
to chapter 2.8
2 When the cuvettes is replaced,exit the program,re-login and select to test
water blank.
4.2.4.2 Clearing Uncompleted Requests

The current sample records may include some samples that have been requested but have no test
results. You can delete them according to your special needs. Select Maintenance>Clear Uncompleted
Request. The following prompt appears.
Click Yes to delete the uncompleted sample requests; or click No to abort and return to the main
screen.
4.2.4.3 Saving Sample Results to History Database

On the LW C100plus, you are allowed to transfer manually the sample test results to the history
database. Select Maintenance> Save Analyzing Data to History. The following prompt appears.
56
Click Yes to transfer the sample results to the history database; or click No to abort and return to
the main screen.
4.2.4.4 Inquiring Error Logs

By selecting Maintenance>Analyzer Running Error Log, you can search for history error logs of the
system occurring during certain period.
After setting up the inquiry conditions, click Search to search for desired error logs. To delete the
selected error log, click Delete Current Error Info; to delete all the error logs, click Clear All Errors Info.
To return to the main screen, click Return.
4.2.5 System Help

You can view the help manual and version information of the system software.
4.2.5.1 Help Manual

Select System Help>Help File. The help manual of the LW C100plus is displayed. It contains
terminology explanation, operation procedures, screen operations, calculation methods, etc. To close
the help manual, click the close button on the upper-right corner.
4.2.5.2 Version Information

To view the version of the system software, select System Help>Version Information. The
following window is displayed.
57
Click OK to close the window and return to the main screen.
4.2.6 Calibration Request

Requesting calibration tests
1
Select an item in the Calibration Item Selection Area. Clicking once means to select the
Select one or more calibrators in the Item Calibrator Request Selection Area according to
the calibration type indication on the lower-right corner.
If you need to run calibration tests for multiple items simultaneously, repeat steps 1 and 2
to select desired items and calibrators.
Click Request to request calibration tests for the selected items.
To view the list of calibration requests, click Calibration Request List.
58
To set up calibrators, click Calibrator Setting.
4.2.7 Testing Request

To request tests of routine and QC samples, select the Testing Request icon in the shortcut
buttons area. The following screen is displayed.
Field
Description
Sample ID Sequence number of
the sample.
Operation
Batch
Request
Number of samples
requested for the
same test items.
Enter the number of samples requested for the same test

items.
Sample
Disk
Sequence number of
the
sample
disk.
There are 4 virtual
sample disks in total.
Sample
Position
Position of the sample

on
the
selected
sample disk. There
are 40 positions on
each sample disk.
Enter it in the edit box; or click the Position Remained View

button and select one from the remaining positions.
Position
Remained
View
Used to view the

empty positions on
the current sample
disk.
Click this button. The following window appears, displaying

all remaining positions on the current disk. To select a
position, click the number button and click OK.
59
Field
Description
Operation
Dilution
test
Select method
dilution test.
Mutiple
Dilution ratio
.It ranges from 2.5 to 100.If the dilution test is manual

dilution or auto-dilution,follow the software instruction to
input Mutiple.if the dilution test is auto retest,no input is
needed.
Original
volume
The original sample

volume
It ranges from 2 to 100ul,If the dilution test is auto dilution,

follow the software instruction to input Volume.If the the
dilution test is manual dilution or auto rest,no input is
need.The total volume after dilution ranges from 150 to
500ul.And the original volume of reaction liquid(without
dilution) is between 150 and 450ul.
Sample
Type
Type of the sample.
STAT
Used to set
sample as STAT.
When selected, the sample is STAT and should be

analyzed immediately.
Sample
Blank
Select to test sample

Blank.
for
the
Select from the pull down list.It includes manual

dilution,auto-dilution and auto retest. When calculating
results,the system will multiply the set dilution ratio
automatically.
When selected,the sample will be used to test sample

blank.Sample blank is the test using H20 as reagent and
sample applied to be tested as sample.

Requesting a sample
1
Enter the sample No. in the Sample Number field.
Set the sample disk, tube position and sample type.
If the sample needs to be analyzed upon emergent needs, select the STAT check
box.
Select desired items in the Item Test Selection Area, and select desired profiles in
the Profile Selection Area. Clicking once means to select, and clicking again means to
deselect it. If you want to set up profiles, click the Profile Setting button and then operate
in the displayed window.
Click Request.
Requesting samples in batch

1
Enter the start sample No., and then enter the number of samples you want to
request.
60
2
3
Set the sample disk, tube position and sample type.

Select desired items in the Item Test Selection Area, and select desired profiles in
the Profile Selection Area. Clicking once means to select, and clicking again means to
deselect it. If you want to set up profiles, click the Profile Setting button and then operate
in the displayed window.
Click Request.
NOTE
1. In case of requesting samples in batch, the sequence No. and tube position on
the sample
disk are determined increasingly from the start sample No. and position.
2. Batch request and single-sample request can be performed simultaneously.
Viewing requested samples

1
Click
or
to view the first or last sample request; click
to view the previous or next sample request.
or
Editing sample request

1
Go to the desired sample No. by using the

buttons.
and
If you want to delete an item from a requested sample that has not been analyzed,
move the cursor to the item and right click the mouse. A new window appears. Click
Delete in the new window.
If you want to add an item, select the desired item in the Item Test Selection Area and
click Request. Please note that the samples that are being analyzed cannot be modified.
4.2.8 Fast Mode Request

To request tests of routine and QC samples quickly, select the Fast Mode Request icon in the
shortcut buttons area. The following screen is displayed.
61
The operation procedures of fast mode request are the same as those of routine sample request. See
section 4.2.7 for details.
NOTE
Fast mode request is applicable to single-reagent items only.
4.2.9 Starting Analysis

Click the Start icon in the shortcut buttons area. The following window is displayed. Select the
test type and sample range, and then click OK to start analysis.
62
If you want to analyze the samples quickly, mark the checkbox in front of Fast Mode.
If not, proceed to the next step.
Select a reagent disk (No.1-No.5) and sample disk (No.1-No.4) to run the tests.
To run a reagent blank automatically for each item, mark the checkbox in front of
Auto Reagent Blank Test. Then proceed to the next step.
If you want to run a reagent blank for certain items, click the Reagent Blank Test
button, select desired reagents in the pop-up window, and then click OK. Please note
clicking once means to select the item, and clicking again means to deselect it.
If QC tests are included in the current batch, click the QC Test button. Clicking once
means to select it, and clicking again means to deselect it.
Click the Routine Test button; then enter the start and end sample No. in the
following edit boxes. Void means to run all routine tests.
Click OK to start the analysis.
NOTE
The LW C100plus can run the reagent blanks, QC tests and routine samples
simultaneously, which are given with the following priority.
1. Reagent blank tests
2. QC tests
3. Routine samples
NOTE
1. Once the Reagent Blank Test, Calibration Test and QC Test buttons are selected,
all such
tests currently requested will be run.
2. As for routine samples, you can specify the sample number and analyze desired
samples.
If you only enter the start sample number, all samples following it will be
analyzed; if
you only enter the end sample number, all samples before it will be analyzed; if
you
enter neither of them, all the requested samples will be analyzed.
4.2.10 Pausing Analysis

This function is used to stop test that has not been adding R1 for a short time.For test that has
already been added R1,S(sample) and R2 will be continued to be added.After click the button
Pause,a prompt screen pops up.See the figure below:
Click continue to start pause function and the analyzer will be in a status of pause.See the
figure below.Click cancel if you dont want to start pause function.
63
After the wait time of the pause is finished,a prompt screen pops up as below.At this time,the
reaction disk is the only moving part that continues moving.Probe and reagent/sample disk are both
stopped and you can add sample and reagents.Click start to return to normal test,click cancel to stay
in pause status.
Note
When in the status of pause,the probe and reagent/sample disk are still in
operation.For safety,please add sample and reagents only when the pause is
finished.
4.2.11 Stopping Analysis

If you need to stop the analysis, click the Stop icon in the shortcut buttons area to display the
following prompt. You are recommended not to use this function unless it is necessary.
Click OK to stop the analysis; click Return to cancel.
4.2.12 Viewing Test Results

If needed, you are allowed to view the status and test results of all routine samples and QC
tests. Click the Result Check icon in the shortcut buttons area. The following screen is displayed.
64
Field
Description
Patient
Name of the
patient.
Operation
Sex
Gender of the
patient.
Age
Age of the
patient.
Enter the age in the first edit box and select a unit from the
pull-down list box.
Register
No.
Medical record
number of the
patient.
Admiss.
No.
Admission
number of the
patient.
Sent
From
The department
where the
patient is
treated.
Enter the code or name of the department.
Bed No.
Bed number of
the patient.
Diagnosi
s
Clinical
diagnosis of the
patient.
Select it from the pull-down list box or enter it with your keyboard.
Sender
The doctor who

issues the
inspection sheet
for the patient.
Enter the code or name of the doctor.
Send
Time
The time when

the sample is
Select it from the pull-down list box or enter it with your keyboard.
65
Field
Description
sent for
analysis.
Sample
Type
Type of the
sample.
Add
Add the sample

type
Status of the
sample.
Sample
Status
Add
Add the Sample

Status
Operation

Click to add sample type.
Click to add Sample Status.
Auditor
The person who

reviews the test
report.
Remark
Special notes or
other comments
for the sample.
Enter them with your keyboard.
Used to delete a
routine sample
that is not
analyzed and
associated
items.
Click Delete One. The following prompt pops up. Click OK to

delete the selected sample.
Delete
One
Delete All
Used to delete
all routine
samples that are
not analyzed
and associated
items, as well as
those finished
samples.
Click Delete All. The following prompt pops up. Click OK to delete
all the samples.
66
Field
Description
Used to search
for desired
samples that are
analyzed on the
current day.
Operation
Search
Sample
Used to delete
single test result
of current
sample
Delete

Viewing current test results
1
Select desired sample in the Routine Sample List.
The result list in the middle right of the screen shows all test results of the selected
sample. If an item is not finished, no result will be displayed.
Select an item that has a test result, and then click Reaction Curve to view its
reaction curve and reaction data.
Entering patient information
In the Routine Sample List, select a sample for which you want to enter the patient
information.
Enter the patient information in the upper-right part of the screen, and then click
Save.
Go to the next sample and repeat steps 1 and 2.

Setting up printing template
Click the Template button. A new window is displayed.
Select an existing template, or create a new one and set it as the default.
Printing test results
To print all the test results, select the All Samples radio button and then click Print.
67
To print the test results of the selected sample, select The Current Selected Sample
radio button and then click Print.
To print the specified test results, select the Select Sample radio button, enter the
sample number in the following edit box and then click Print.
4.2.13
System Status
In the upper-right part of the main screen shows various statuses for you to monitor the system
conveniently. The statuses include lamp intensity, remaining purified water, waste liquid,system running
status and temperature.
4.2.14
Exiting the System
When the system is in standby status, you can exit it by selecting the Exit icon in the shortcut
buttons area.
If it is a normal shutdown,click OK to exit the system software.

If the analyzer is not to be used in a long period (several days),click to select Long-leave mode
first,and then click OK to exit the system software.
NOTE
1If it is shut down in normal mode,the cuvettes will be filled in with purified water.
2If it is shut down in Long-leave mode,the water in the cuvette will be drained
out.
4.2.15 Emergency Exit

When the system experiences a failure during analysis and cannot be shut down normally, you
can use the emergency exit function. As for emergency exit, the system will quit directly without
performing any shutdown procedures.
68
After selecting the Exit Emergently icon in the shortcut buttons area, the above prompt pops
up. Click OK.
4.2.16 Hiding/Displaying Menus

If you want to hide the menu bar, click the Hide Menu icon. The menu bar disappears and the
Hide Menu icon changes to Show Menu. Click it again. The menu bar appears and the Show Menu
icon changes to Hide Menu.
Before clicking Show Menu:
After clicking Show Menu:
After clicking Hide Menu again:
4.2.17 Viewing Temperature Curve

Click the temperature curve icon in the shortcut buttons area. The following window is
displayed, showing the dynamic changes of reaction temperature via a curve.
To increase or decrease the Y-coordinate, move the scroll bar upwards or downwards in
;
69
To increase or decrease the X-coordinate, move the slider rightwards or leftwards in

;
Click Return to close the temperature curve window and return to the main screen.
4.2.18 Sample Disk

Select Sample Disk in the shortcut buttons area. The Sample Disk Status View screen is
displayed. You are allowed to view the testing status of all requested samples on the sample disk and of
all requested calibrators on the calibrator disk.
Viewing sample disk status

1
Select desired sample disk tab on the Sample Disk Status View screen.
The sample disk graph shows the test types and test status with different graphics and
colors.
Select a sample on the sample disk graph. The Selected Sample Info Display Area
shows the number and type of the sample; the Selected Sample Test Result Display Area
shows all requested items and test status of the sample; the Display Selected Sample All
Tests Estimated Left Time block shows the time needed to finish the sample runs.
Select a finished item in the Selected Sample Test Result Display Area, and then click
Reaction Curve to view its reaction curve and data.
Click Return to close the window and return to the main screen.
4.2.19
Reagent Disk
Select Reagent Disk in the shortcut buttons area. The Reagent Disk Position Setting screen is
displayed. You are allowed to view and set up reagent positions and volumes, and to check the
reagent inventory when the system is in standby status.
70
Viewing reagent disk status

1
Select desired reagent disk tab on the Reagent Disk Position Setting screen.
The reagent disk graph shows the status of each reagent position with occupied
and idle.
In the Item Display Area, grey means the reagent of the item has been positioned,
and yellow means the opposite.
3
4
In the Reagent Set Display Area, you are allowed to view the positions and
inventory of the reagents.
Setting up reagent positions

1
In the Item Display Area, click an item box indicated by yellow. In case of a
double-reagent item, you need to select a R1 or R2. Then double click an empty
position on the reagent disk graph. The selected reagent is positioned.
Changing reagent position
1
On the reagent disk graph, select a reagent that you want to relocate, and then
double click an empty position to hold it.
Releasing a reagent position
1
On the reagent disk graph, select a reagent position that you want to release, and
then click Cancel Reagent Position.
Checking reagent inventory
1
2
Click Reagent Volume Check to display a new window. Select a reagent that you
want to check the inventory, and then click OK.
71
NOTE
1. In case of a double-reagent item, you are required to position both R1 and R2
on the same reagent disk.
2. You are allowed to check reagent inventory only when the system is in standby
status.
4.2.20
Reaction Disk
Select Reaction Disk in the shortcut buttons area. The View Reaction Disk Status screen is
displayed. You are allowed to view the item and test status of each reaction cuvette.
Viewing reaction disk status

1
The reaction disk graph shows the test status of each cuvette with different colors.
Click a cuvette position. The Select Cuvette Test Items in the Current Day area lists all
items of the cuvette that have been finished or are being analyzed.
Select a test record. The sample number and type are displayed in the Selected Test Item
Details block.
3
4
To view the reaction curve and data of an item, select a finished test and then click
Reaction Curve.
4.2.21 Early Warning and Warning Messages

Select Early Warning or Warning Messages in the shortcut buttons area. The Error Info screen
is displayed. You can view all the current alarm messages, including the error description, probable
causes and corrective actions. When a new early warning occurs and is not viewed, the Warning
Messages button appears in bright yellow and restores when the a Early Warning is observed.
When a new warning occurs and is not viewed, the Warning Messages button appears in bright red
and restores when the alarm message is observed. The Error Info screen is as follows.
72
To view the history alarm messages, see Inquiring Error Logs in section 4.2.4.5 Inquiring Error
Logs.
73
Chapter 5 General Operation Procedures
Chapter 5General Operation Procedures

5.1 Basic Operations
1.
Adding
item
an
2.
3.
4.
1.
Modifying
item
parameters
2.
3.
4.
1.
Deleting an
item
2.
3.
4.
1.
Adding
control
2.
3.
4.
1.
Modifying
control
information
2.
3.
4.
1.
Deleting
control
a
2.
Click the Show Menu shortcut button on the main screen to show the menu
bar.
Select Test Setting and then select Item Parameter in the pull-down menu.
The Set Tested Item Parameter screen is displayed.
Click add, and then enter the item parameters properly according to your
reagent package insert.
Click Save.
bar.
Select an item you want to modify, click Modify, and then change the item
parameters properly according to your reagent package insert.
Click Save.
bar.
Select an item you want to delete and click Delete to display a prompt.
Click Yes.
bar.
Select Test Setting and then select QC Setting in the pull-down menu. The
QC Setting Management screen is displayed.
Click Add, and then set the control parameters properly, including control
name, target value and SD for each item, and cumulative sum check rule.
Click Save.
bar.
Select a control you want to modify, click Modify, and then change the
control parameters properly, including control name, target value and SD for
each item, and cumulative sum check rule.
Click Save.
bar.
74
Adding
a
calibrator
3.
4.
Select an control you want to delete and click Delete to display a prompt.
Click Yes.
1.
bar.
Select Test Setting and then select Calibration Setting in the pull-down
menu. The Calibration Setting Management screen is displayed.
Click Add, and then set the calibrator parameters properly, including
calibrator name, SD for each item, and position on the calibrator disk.
Click Save.
2.
3.
4.
1.
Modifying
calibrator
information
2.
3.
4.
1.
Deleting a
calibrator
2.
3.
4.
1.
Setting up
reagent
positions
2.
3.
4.
1.
Changing
reagent
position
2.
3.
4.
1.
Releasing a
reagent
position
2.
3.
4.
5.
bar.
Select a calibrator you want to modify, click Modify, and then change the
calibrator parameters properly, including calibrator name, SD for each item,
and position on the calibrator disk.
Click Save.
bar.
Select an calibrator you want to delete and click Delete to display a prompt.
Click Yes.
Click the Reagent Disk shortcut button on the main screen. The Reagent
Disk Position Setting screen is displayed.
Select desired reagent disk tab.
Select a reagent you want to locate. Note that you need to select both R1
and R2 for a double-reagent item.
Double-click an empty position on the reagent disk graph. The selected
reagent is positioned.
Select a reagent you want to relocate on the reagent disk graph.
Double-click an empty position on the reagent disk graph. The selected
reagent is relocated.
Select a reagent position that you want to release.
Click the Delete button to display a prompt.
Click Yes.
75
Running
reagent
blanks
1.
2.
3.
4.
5.
6.
Check the reagents and ensure all bottles are uncapped.

Put the distilled water in 40 sample Position.
Click the Start shortcut button on the main screen. The Start Test window is
displayed. Set the test conditions.
Select a reagent disk (No.1-No.5) from the pull-down list box.
Click the Reagent Blank Test button; then select desired reagents in the
displayed window and click OK.
Click OK.
1.
Running
calibration
tests
Click the Calibration Request shortcut button on the main screen. The
Calibration Request screen is displayed. Select a desired item, calibrators
and calibration rules.
2. Repeat step 1 until all desired items are requested for calibrating.
3. Click Request.
4. Place the correct calibrators in assigned positions of the sample disk.
5. Check the reagents again and ensure all bottles are uncapped.
6. Click the Start shortcut button on the main screen. The Start Test window is
i. Select a reagent disk (No.1-No.5) from the pull-down list box.
ii. To run a reagent blank automatically for each item, mark the checkbox in
front of Auto Reagent Blank Test. Then proceed to the next step.
iii. Click the Calibration Test button. Clicking once means to select it, and
clicking again means to deselect it.
iv. Click OK to start running the calibration tests.
1.
Running
QC tests
Click the Testing Request or Fast Mode Request shortcut button on the main
screen. The Sample Test Request screen is displayed.
2. Click the QC Test radio button in the Test Type Request block; select desired
control, sample disk (No.1-No.4) and position (1-59), and items or profiles;
then click Request.
3. Repeat step 2 until all desired controls are requested. Click Return to exit
and return to the main screen.
4. Select Sample Disk in the shortcut buttons area. The Sample Disk Status
View screen is displayed. Click the controls on the sample disk graph and
check if all of them are requested correctly.
5. Place the correct controls in assigned positions of the sample disk.
i. If you want to analyze the controls quickly, mark the checkbox in front of
Fast Mode. If not, proceed to the next step.
ii. Select a reagent disk (No.1-No.5) and sample disk (No.1-No.4) to run the
tests.
iii. Click the QC Test button. Clicking once means to select it, and clicking
again means to deselect it.
iv. If routine samples are included in this batch, click the Routine Test button;
then enter the start and end sample No. in the following edit boxes. Void means
76
to run all routine tests.

v. Click OK to start running the tests.
1.
Running
routine
samples
Click the Testing Request or Fast Mode Request shortcut button on the main
screen. The Sample Test Request screen is displayed.
2. Enter the sample number; select a sample disk (No.1-No.4) and position
(1-39), and items or profiles; then click Request.
3. Repeat step 2 until all desired samples are requested. Click Return to exit
and return to the main screen.
4. Select Sample Disk in the shortcut buttons area. The Sample Disk Status
View screen is displayed. Click the samples on the sample disk graph and
check if all of them are requested correctly against the inspection sheet.
5. Place the correct samples in assigned positions of the sample disk.
i. If you want to analyze the controls quickly, mark the checkbox in front of
Fast Mode. If not, proceed to the next step.
ii. Select a reagent disk (No.1-No.5) and sample disk (No.1-No.4) to run the
tests.
ii. To run a reagent blank automatically for each item, mark the checkbox in
front of Auto Reagent Blank Test. Then proceed to the next step.
iv. If you want to run a reagent blank for certain items, click the Reagent Blank
Test button, select desired reagents in the pop-up window, and then click OK.
Please note clicking once means to select the item, and clicking again means to
deselect it.
v. If QC tests are included in the current batch, click the QC Test button.
Clicking once means to select it, and clicking again means to deselect it.
vi. Click the Routine Test button; then enter the start and end sample No. in
the following edit boxes. Void means to run all routine tests.
vii. Click OK to start running the tests.
5.2 Operation Procedure of New Item Analysis

1
Add an item and set up its various parameters properly.
Set up reagent position for the item.
Add calibrators for the item or set up the concentrations of existing calibrators for it.
Add controls for the item or set up the target values and SDs of existing controls for it.
Request calibration tests for the item.
Start running the calibration tests.
When calibration tests are finished successfully, request QC tests and start running them.
If the system is surely under control after the QC analysis, start running routine samples.
77
Note
Reagen blank test is a must for the first calibration of a new item.
5.3 Routine Operation Procedure

1
Checking before powering on

a)
Check and make sure sufficient printing paper is prepared. If not, add more paper.
b) Check if proper power supply is provided and if the power cord is connected to the
outlet correctly.
c) Check the connections among the printer, operation unit and analyzing unit. Make sure
the cables are connected correctly and reliably.
d)
Place 5ml distilled water in No.60 position of the sample disk.
e) Open the front doors of the analyzing unit and check if enough purified water is
prepared. If not, add more water.
f)
Check if enough acid/alikla wash solution is prepared,.If not,add more wash solution.
g)
Empty the waste tank and check if waste liquids can be discharged easily.
h) Check the sample probe and mixer, and make sure they are not bent, contaminated or
do not drip.
i)
Check the sample syringe for bubbles and leakage.
j)
Uncap the reagent bottles.
NOTE: Biohazard
1. All waste liquids are infectious. Please dispose them compliantly with international
standards or local regulation..Please wear gloves when working with waste liquids.
2. All system parts are with risk of biohazard. Please wear gloves when working with
those parts.
2
Powering on
Switch on the power in the sequence as presented below:
a) Switch the main power to ON, which is at the right side of the rear panel of the
analyzing unit
b) Press the power switch on the right panel of the analyzing unit. The indicator is on.
c) Turn on the monitor of the computer.
d) Turn on the computer.
e Turn on the printer.
3
Starting the operating procedure

Double-click the shortcut icon of the operating software on the desktop. Then the system
performs the startup procedure in the following order: about 18min.
a) Reset all moving parts.
b) Turn on temperature control and heat the reaction disk.
c) Trun on the lamp.
d) Measure the background of every wavelength.
78
e) Wash cuvettes.
f) Measure the water blank
g) Check the lamp status.
NOTE: Alarm and Dirty Cuvettes

1. When an alarm occurs during the startup process, click the Warning Messages button
on the main screen to view the alarm message and corresponding corrective actions.
2. When the analyzer starts up,it will monitor the lamp status automatically.If it indicates
that the lamp intensity is weak,please replace the lamp immediately.
General setting
a)
Set up the information of hospital, departments and doctors.
b)
Set up user name, initial password and operation privileges.
c) Set up information of item printing order and result unit.

Item parameters setting
Set up the item parameters properly according to the reagent package insert.
NOTE: Parameters
Incorrect analysis parameters may cause erroneous test results. Please consult
Landwind or your reagent supplier for correct parameters.
6
Set up reagent positions

Set up the reagent position for each item.
NOTE
1. In case of a double-reagent item, you are required to position both R1 and R2
on the same reagent disk.
7
Calibration setup
a)
Add one or more calibrators.
b)
Set up positions of the calibrators on the calibrator disk.
c)
Set up the concentration of the calibrators for each item.
QC Setup
a)
Adding one or more controls.
b)
Set up the target value and standard deviation of the controls for each item.
c)
Set up the cumulative sum check rule of the controls for each item.
Testing request
1
Request reagent blank tests.
Request calibration tests.
Request QC tests.
Request routine samples.
10 Preparation for analysis

a)
Place the reagents in their assigned positions. If the inventory is low, add more
79
reagent.
b)
Place the correct calibrators in their assigned positions on the sample disk.
c)
Place the correct controls in their assigned positions of the sample disk.
d)
Place the correct samples in their assigned positions of the sample disk.
NOTE: Probe Blockage

1. Check the reagents and samples carefully for insoluble matters, such as
fibrin and protein; otherwise the reagent probe or sample probe may be
blocked.
2. If the samples include insoluble matters, extract the supernatant and transfer
it to a clean tube.
11 Starting analysis
a)
Click the Start shortcut button on the main screen.
b)
Select desired test type.
c)
Set the sample range for analysis.
d)
Click OK to start analysis.
NOTE
The LW C100plus can run the reagent blanks, QC tests and routine samples
simultaneously, which are given with the following priority.
1. Reagent blank tests.
2. QC tests.
3. Routine samples.
12 Viewing test results
1.
Viewing calibration curve
a)
Click the Show Menu shortcut button on the main screen to show the menu bar.
b)
Select Stat./Search and then select Calibration Search in the pull-down menu. The
Calibration Result Search screen is displayed.
c)
Set the start and end date for inquiry, select an item in the Search Item Selection Area, and
then click Search. All qualified calibration records are displayed in the Search Result
Display Area in the right part of the window.
d)
To view the detailed information of a calibration record, select a test result in the Search
Result Display Area and then click Details.
2.
Viewing QC status
a)
Click the Result Check button on the main screen.
b)
Click a control name in the lower-left part of the screen. All requested items of the control
are displayed. To view the reaction curve and data of an item, select a finished item and
80
then click Reaction Curve.

3.
Viewing sample results
a)
Click the Result Check button on the main screen.
b)
Click a sample number in the left part of the screen. All requested items of the sample are
displayed. To view the reaction curve and data of an item, select a finished item and then
click Reaction Curve.
c)
To set up the patient information of a sample, select the sample number, enter the patient
information in the upper part of the screen, and then click Save.
d)
If you want to rerun an item, mark the Rerun checkbox to the right of the test result, and
then click the Rerun button.
13 Adding tests
a)
Add routine samples
b)
Add STAT samples
c)
Add QC tests
NOTE
1. The LW C100plus allows you to add as many routine samples and QC tests as
you need during the analyzing process.
14 Shutdown
Click the Exit button on the main screen. The system performs the shutdown procedure as
follows, which may take about 55 min.
a)
Wash all cuvettes.
b)
Fill the cuvettes with purified water.
c)
If it is Long-leave modeit will drain out the water of all cuvettes.
d)
Exit the operating system
15 Power-off
Switch off the power in the sequence as presented below:
a)
Place the Power of the analyzing unit to OFF.
b)
Turn off the computer.
c)
Turn off the monitor.
d)
Turn off the printer.
NOTE
1. The main power of the LW C100plus is located in the lower part of the rear panel
and shall not be turned off if not specially required.
2. To turn off the main power, place the power switch to OFF.
16 Checking after powering off
81
a)
Take out samples, calibrators and controls from the sample disk.
b)
Cap the reagent bottles.
c)
Wipe the front panels of the analyzing unit.
d)
Remove the stains and water on the sample probe and mixer.
Check the sample syringe for bubbles and leakage.
82
Chapter 6 Analysis Principles and Calculation Methods
6.1 Analysis Principles

Based on the theory of liquids absorbance of light or light transmission in suspension, the LW
C100plus measures the absorbance of the reaction liquid at each measuring point during the
reaction process, and calculates the concentration or activity of the analytes with corresponding
calibration parameters or calculation factors according to the absorbance change before and
after the reaction or the change rate of absorbance during reaction.
6.2 Analysis Procedure

This section introduces the analysis procedure of the LW C100plus by actions, action
positions, testing flow and measuring points.
6.2.1 Actions
The LW C100plus finishes all the tests by performing the following steps repeatedly:
The reaction disk rotates to carry the cuvettes to the first set of wash probes and wash them
automatically.
The reaction disk rotates 87 cuvettes positions (during rotating the absorbance of the reaction
liquid is measured) and then pauses; rotates to R1 dispensing position, pauses; rotates 90
cuvettes positions,then pauses.This whole process is called one period.
During the 1st and the 81st period, R1, sample and R2 are dispensed and the reaction is
monitored. Absorbance measurement is performed once in each period.
In the 81st period, the cuvettes are carried to the first set of wash probes and then washed.
After that, the next cycle begins.
83
6.2.2 Action Positions
6.2.3 Testing Flow

The LW C100plus performs tests following the given work flow. Each reaction includes 49 test periods,
each of which takes 24 seconds in fast mode and 36 seconds in routine mode. See the figure below.
6.2.4 Measuring Point

Absorbance measurement is performed once in every period of the same reaction. There are
49 measuring points during the whole reaction process, and the interval between two is 24s in fast
mode and 36s in routine mode. See the figure below.
84
6.3 Analytical Methods

According to the reaction speed of the mixture, the LW C100plus provides three types of
analytical methods: endpoint, two-point and Kinetic. The following sections introduce these three
methods in detail.
6.3.1 Endpoint
With the analytical method of endpoint, the sample & reagent mixture reacts completely; all
analytes are changed to products under monitoring; the absorbance of the reaction liquid does not
change any more; the absorbance change before or after the reaction is directly proportional to
the initial concentration of the analytes.
The figure below shows a typical endpoint reaction curve.
85
6.3.2 Two-point
With the analytical method of two-point, the reaction velocity is directly proportional to the
concentration of the analytes within a specific period. Since the analytes are consumed
continuously, the reaction velocity decreases, and so does the change rate of the absorbance.
During this period, the absorbance change is directly proportional to the initial concentration of the
analytes.
The figure below shows a typical two-point reaction curve.
6.3.3 Kinetic
With the analytical method of Kinetic, the reaction velocity reaches the maximum and keeps
unchanged within a specific period; the reaction liquid are changed to products evenly at the
maximum speed; the absorbance of the analytes decreases or increases evenly and the change
rate ( A/min) is directly proportional to the concentration or activity of the analytes. This method
is mainly used to measure enzyme activity.
The figure below shows a typical Kinetic reaction curve.
86
6.4 Absorbance and Response

6.4.1 Absorbance
On the LW C100plus, the calculation formula of absorbance is as follows:
Absorbance = Log(ADwater - ADdark) / (ADliquid - ADdark)
Where,
1. Log stands for logarithm with the base number of 10.
2. AD is the value obtained through photoelectrical and analog-digital conversion of the
transmitted light.
3. ADdark is the AD value when the lamp is off;;ADwater is the AD value when the cuvette is
filled
with purified water.; ADliquid is the AD value when the reaction cuvette is filled with reaction
mixture.
4.The absorbance data on the reaction curve is 20000 times of the data calculated by using
the above
formula.
6.4.2 Response
On the LW C100plus, response refers to the absorbance change or change rate within the
start and end reaction points. It is a crucial intermediate factor and indispensible for calculating
calibration parameters and concentration. The calculation method of response varies with
different analytical methods, which are described as follows:
1. Endpoint analysis
Response = Absorbance at end point (Absorbance at start point Volume correction
87
factor)
Where,
The start and end points can be defined on the Test Setting> Item Parameter screen.
The absorbance, in case of single-wavelength, is that measured at the primary wavelength; in

case of double-wavelength, it is the difference between the absorbance measured at the
primary and secondary wavelengths.
Volume correction factor = (Volume at start point)/(Volume at end point)
To correct the response with sample blank, you should request sample blank test separately,
whose response R Sb is same as the above. The response after being corrected by sample
blank is
R' R RSb
2. Two-point analysis
Response =Absorbance at end point Absorbance at start point/(T2-T1)
Where,
The start and end points can be defined on the Test Setting> Item Parameter screen.
Absorbance at end point is the absorbance of the reaction end periodAbsorbance at

start point is the absorbance of the reaction start period.
T2 is the time of the reaction end pointT1 is the time of the reaction start point.

3. Kinetic analysis
Response = Absorbance change rate per minute within the start and end points
Where,
The start and end points can be defined on the Set Tested Item Parameter screen.

88
6.5 Calibration
6.5.1 Calibration Methods
The LW C100plus provides two calibration methods: linear and nonlinear. Linear calibration
includes one-point, two-point and multi-point, which are mainly used for items determined by
colorimetry. Nonlinear calibration includes Logit-4P, Logit-5P, Exponential-5P, Polynomial-5P and
Spline, which are mainly used for items determined by turbidimetry.
6.5.2 Calibration Parameters

Each calibration method has certain parameters and calculation methods and is introduced in
detail.
1. One-point linear calibration
Formula: C=R/k, with 1 calibration parameter, e.g. k.
K=Rstd/Cstd
Where, Cstd is the concentration of calibrator, and Rstd is the response of calibrator.
2. Two-point linear calibration

Formula: C=(R-b)/k, with 2 calibration parameters, e.g. k and b.
k= (R2-R1) /(C2-C1)
b= R1- C1(R2-R1) / (C2-C1)
Where, C1 and C2 are the concentration of calibrators 1 and 2; R1 and R2 are the response
of calibrators 1 and 2.
3. Multi-point linear calibration

Formula: C=(R-b)/k, with 2 calibration parameters, e.g. k and b.
The calibration parameters are calculated with multi-point linear regression.
4. Logit-4P
Formula: R=R0+K/[1+e
-(a+blnC)
], with 4 parameters, e.g. R0, K, a and b. This method
requires at least 4 calibrators. The concentration (or activity) of calibrator 1 is 0, and the
corresponding R is equal to R0. Other parameters are calculated with iterative method.
5. Logit-5P
89
Formula: R=R0+K/[1+e
-(a+blnC+c*C)
], with 5 parameters, e.g. R0, K, a, b and c. This method
requires at least 5 calibrators. The concentration (or activity) of calibrator 1 is 0, and the
6. Exponential-5P
[alnC+b(lnC)2+c(lnC)3]
Formula: R=R0+Ke
, with 5 parameters, e.g. R0, K, a, b and c.
This
method requires at least 5 calibrators. The concentration (or activity) of calibrator 1 is 0, and the
7. Polynomial-5P
Formula: LnC=a+b(R-R0)+c(R-R0)2+d(R-R0)3, with 5 parameters, e.g. R0, a, b, c and d. This
method requires at least 5 calibrators. The concentration (or activity) of calibrator 1 is 0, and the
8. Spline
Formula: C-Ci=R0i+ai(C-Ci)+bi(C-Ci)2+ci(C-Ci)3-R, with 4i parameters, e.g. R0i, ai, bi and ci.
This method requires at least 2 calibrators. The calibration parameters are calculated with
iterative method.
6.6 Concentration
1. With the analytical method of Kinetic, calibration can be neglected. You should enter the
calculation factor F. The concentration is the product of response R and F. For other types of
items, you should run calibration tests first. The concentration will be calculated with the
obtained calibration parameters.
2. For the calibration methods of linear, Logit-4P or Polynomial-5P, the concentration can be
calculated with the calibration parameters and response R.
3. For the calibration methods of Logit-5P, Exponential-5P or Spline, the concentration can be
calculated with the dichotomy method based on the response R and calibration parameters.
6.7 QC
6.7.1 QC Rules
The LW C100plus takes Westgard multi-rule as the default.
The Westgard multi-rule includes 6 sub-rules, which are listed in the table below:
Symbol
Explanation
QC Conclusion
90
Symbol
Explanation
QC Conclusion
12S
One control value exceeds 2 standard

deviations.
Warning
13S
One control value exceeds 3 standard

deviations.
Out of control (random error

or system error)
22S
Two consecutive control values for one level

exceed 2 standard deviations.
Out of
error)
control
(system
R4S
The difference between two consecutive

control values exceeds 4 standard
deviations.
Out of
error)
control
(random
41S
Four consecutive control values for one level

exceed 1 standard deviation.
Out of
error)
control
(system
10X
Ten consecutive control values for one level

lie on one side of the mean.
Out of
error)
control
(system
The QC judgment flow of the LW C100plus is illustrated in the figure below:
6.7.2 QC Types
The LW C100plus provides three QC types, which are real-time, daily and day-to-day. QC
judgment is made according to the set QC rule.
Real-time QC: 10 consecutive QC data are collected on the same day for judgment.
Daily QC: All QC data are collected on the same day for judgment.
Day-to-day QC: All QC data are collected on different days for judgment.
6.7.3 QC Plot
The LW C100plus provides three types of QC plots: Levey-Jennings (L-J), cumulative sum
check and Twin Plot.
1. L-J plot
The measured QC values are the Y-coordinates. A horizontal line is leaded from the target
91
value, with +1SD, +2SD and +3SD marked above it, and -1SD, -2SD and -3SD marked below it.
Based on the six values, six straight lines are drawn in parallel with the target value line and
marked with 1SD, 2SD and 3SD. The L-J plot is formed by connecting the adjacent points of
measured QC values in the coordinate system.
2. Cumulative sum check plot
The cumulative sum of a control is calculated and taken as the Y-coordinate, and the test time
is the X-coordinate. A horizontal line is leaded from 0 and another two straight lines are drawn in
parallel with it at the control limit h above and below it. The control limit is calculated automatically
according to the QC rule you have set up. The cumulative sum plot is formed by connecting the
adjacent points of cumulative sums marked in the coordinate system. Any point beyond the two
limit lines is deemed out of control.
3. Twin Plot
A Twin Plot can be generated if an item is run with two controls of different concentration.
According to the set target value and SD of each control, the measured value of the
low-concentration control is the X-coordinate and that of the high-concentration control is the
Y-coordinate. The average of the two values is used to draw the center line. The 1SD, 2SD and
3SD are adopted to draw lines parallel to the X-/Y-axis. The measured results of the two controls
at each time constitute a point, which is marked in the coordinate system. An example of Twin-Plot
is shown below.
3SD
2SD
1SD
-1SD
-2SD
-3SD
-3SD -2SD -1SD
1SD
2SD 3SD
The figure above can reflect system and random errors. The data within the blue frame
(2SD) means in control; the data between the red and blue frames in the first or third quadrant
means system error; the data between the red and blue frames in the second or fourth quadrant
92
means random error.
6.8 Other Calculations

6.8.1 Calibration Curve
1. Calibration sensitivity
If the difference between the responses of highest-/lowest-concentration calibrators is lower
than the set value, the calibration is failed.
2. Response of blank calibrator
If the response of a zero-concentration calibrator is greater than the set value, the calibration
is failed.
3. Calibration repeatability
If the difference between the maximum and minimum response of the three of each calibrator
is greater than the set value, the calibration is failed.
4. SD of calibration curve
Standard deviation is applied to multi-point linear and nonlinear calibration curves only. The
standard deviation (SD) is the square root of the quotient between the square of response
difference (response R and calculated response Ri) and the degree of freedom. The calculation
formulas are introduced as follows.
Multi-point linear calibration
Rij Ri
N
SD=
' 2
i 1 j 1
Nn 2
Where, Rij is certain response of calibrator i; Ri is the response calculated based on the
calibration curve; N is the number of calibrators; n is the number of valid tests.
Logit-4P
Rij Ri
N
SD=
' 2
i 1 j 1
Nn 4
Logit-5P
Rij Ri
N
SD=
' 2
i 1 j 1
Nn 5
Exponential-5P and polynomial-5P
Rij Ri
N
SD=
' 2
i 1 j 1
Nn 5
93
Spline
Rij Ri
N
' 2
i 1 j 1
SD=
Nn 4
5. Correlation coefficient of calibration curve
Correlation coefficient is applied to multi-point linear and nonlinear calibration curves only.
See the formula below:
Cij C Rij R
N
R2
i 1 j 1
Cij C Rij R
N
i 1 j 1
i 1
Where, C is the concentration of a calibrator; R is the response; N is the number of calibrators;

n is the number of valid tests.
NOTE
On the LW C100plus, each calibrator is tested for 3 times. The
concentration is the average of the two values rather than the most
deviated one. Therefore, n is constantly 2.
6.8.2 Substrate Depletion

Substrate
depletion
is
applied
to
Kinetic
and
two-point
analysis
only.
Some
high-concentration (activity) samples cause the substrate to deplete quickly, and the reaction
velocity is deviated from the expected one (zero-order or first-order reaction). To ensure reliable
test results, judgment of substrate depletion is required. See the introduction below.
1. Ascending reaction
If the absorbance at any one or more points is greater than the set value within the start and
end reaction points, substrate is depleted.
2. Descending reaction
If the absorbance at any one or more points is lower than the set value within the start and
end reaction points, substrate is depleted.
6.8.3 Linearity Check

Linearity check is applied to Kinetic analysis only. Within the start and end reaction point, the
94
linearity of the reaction curve is checked against the set value according to the measured value at
each measuring point. The calculation of linearity limit is introduced as follows:
1. If there are more than 9 measuring points within the start and end reaction points,
Linearity limit=(Absorbance change rate at first 6 measuring points - Absorbance change
rate at last 6 measuring points)/Absorbance change rate at all measuring points
2. If 4 Number of measuring points within the start and end reaction points 8
Linearity limit=(Absorbance change rate at first 3 measuring points - Absorbance change
rate at last 3 measuring points)/Absorbance change rate at all measuring points
3. The linearity will not be calculated in the following conditions:
Number of measuring points 3.
The absorbance change rate is lower than 0.006/min, or the difference of absorbance
change rate is lower than 0.006/min.
Reagent blank tests, sample blank tests or blank calibrators are run.
6.8.4 Prozone Check

During the reaction of antigen and antibody, the amount of generated insoluble compound is
closely related to the proportion between antigen and antibody. When antigen and antibody is
proportioned properly, maximum amount of insoluble compound is generated, that is, least light is
passed and absorbance is the highest. Otherwise, amount of insoluble compound is reduced,
more light is passed, and absorbance is decreased. See the figure below. Without prozone check,
very high-concentration samples may produce same amount of insoluble compound as
low-concentration samples and thus an incorrect result may be reported.
Ag/Ab
compound
Equilibrium
zone
Ag surplus
Ab surplus
Ag
The LW C100plus performs prozone check with the following methods.
1. Double-reagent endpoint analysis
See the figure below. L is the start reaction point, M is the end reaction point, N and P are
95
prozone check points. The four points should meet the following equation:
10L19NPM49
Calculation formula of prozone check value (PC):
AM A P
PC M P 100%
AP AN
PN
If PC is larger than the set prozone check value, prozone occurs.
2. Single-reagent endpoint analysis
See the figure below. L is the start reaction point, M is the end reaction point, N and P are
prozone check points. The four points should meet the following equation:
1L10NPM49
Calculation formula of prozone check value (PC):
AM A P
PC M P 100%
AP AN
PN
96
If PC is larger than the set prozone check value, prozone occurs.
6.8.5 Reaction Equilibrium Check

Reaction equilibrium is applied to endpoint analysis only. The LW C100plus checks if the
reaction reaches equilibrium at the end point according to the absorbance measured at each
measuring point.
1. The difference between the absorbance measured at three consecutive measuring points at
and after the end reaction points is calculated.
2. If all the differences are less than 0.01, the reaction has reached equilibrium, and vice versa.
3. If the end reaction point exceeds 47, the system will not perform the equilibrium check.
6.8.6 Lamp Status Check

1. The light intensity will be detected each time when startting up the system.
2. When the light intensity at 340nm is less that 50% of the initial value, the warning information
will comes out to remind you that the light intensity is insufficient and please replace the
lamp in time. At this time,you are allowed to continue the test, but the warning information
will comes out each time before you start the test to remind you that the insufficient light
intensity may affect the test result. ; when the light intensity at 340nm is less than 30% of the
initial value. it will remind you the light intensity is so insufficient that you have to replace the
lamp immediately.At this time,you are not allowed to continue the test and you have to
measure the water blank after you replace the lamp and run the software again.
6.8.7 Cuvette Status Check

The initial value of the ADwater at all wavelengths is set to 50000.The value has to be adjusted
to around 50000 before delivery of the analyzer. and it should not be less than 45000.The 40% of
the initial value is used as the limit value for determining dirty cuvette.If it is lower than the limit
value,the system will warn that the cuvette is dirty.Judgements of dirty cuvette will be made each
time when testing the ADwater.And the judgement is based on the ratio of minimum ADwater to
initial ADwater.
97
Chapter 7 Maintenace
Chapter 7 Maintenance
In order to achieve the best performance, reliability and service life of the system, please
service and maintain the system strictly as instructed by this chapter.
7.1 Preparation of Tools

1. M1.5M2.0M2.5 and M3.0hex wrenches.
2. Cross-headed screwdrivers (large, medium and small).
3. Stainless steel wires with internal diameter of 0.3mm and 0.5mm.
4. Plastic syringe without needle, about 10ml.
5. Clean gauze.
6. Clean cotton swabs.
7. Brush (used to wash the tanks).
8. Non-ion surface active detergent.
9. Absolute ethyl alcohol.
10. 84 disinfectant.
11. Medical gloves.
7.2 Daily Maintenance

7.2.1 Cleaning Panels of Analyzing Unit
The panels of the analyzing unit may be stained by reagents, reaction liquid and serum,
which should be wiped off immediately. Perform the following steps after shutting down the
system everyday:
1
Wipe the panels with a wet towel dipped with wash solution until all stains are
removed.
Wipe the panels again with a wet towel dipped with disinfectant.
After a quarter, dry the wet towel and use it to wipe off the disinfectant from the
panels.
NOTE: Corrosion
Wash solution is chemically corrosive. Please wear gloves when
working with wash solution.
NOTE: Biohazard
The panels should be considered infectious. Please wear gloves when
working around the panels.
7.2.2 Cleaning Sample Probe and Mixer

The probe and mixer may have serum, reagent and water remained on their exterior and tip
and the mixing part. Check the probe and mixer carefully everyday after powering off the system.
If any, perform the following steps to clean them.
98
Figure 7-1: Cleaning sample probe
Move the sample probe to a position convenient for cleaning.
Use a clean cotton swab dipped with absolute ethyl alcohol to gently wipe the
sample probe tip until no attachment is found.
Figure 7-2: Cleaning mixer
Move the mixer to a position convenient for cleaning.
flat part of the mixer until no attachment is found.
NOTE: Flammability
Ethanol is flammable and may be fired. While doing the cleaning,
please ensure the analyzer has been powered off and no more than
10ml ethanol is used near it.
NOTE: Biohazard
All parts should be considered infectious. If necessary, please wear
7.2.3 Cleaning Wash Probes and Nozzle

The wash probes, if not cleaned, may have reaction liquid and water remained on them.
Check the wash probes carefully everyday after powering off the system. If any, perform the
following steps to clean them.
99
Figure 7-3: Cleaning wash probes
1
2
dispense probes and tips until no attachment is found.
aspirate probes and tips until no attachment is found.
Figure 7-4: Cleaning wash probe nozzle
1
2
Use a clean cotton swab dipped with purified water to gently wipe the four
sides and upper/lower part of the probe nozzle until no attachment is found.
four sides and upper/lower part of the probe nozzle until no attachment is
found.
NOTE
Cotton fibrin may stay between the dispense probe and aspirate probe.
Exercise caution while cleaning the probes and remove the remained
cotton fibrin if any.
NOTE: Flammability
Ethanol is flammable and may be fired. While doing the cleaning,
please ensure the analyzer has been powered off and no more than
10ml ethanol is used near it.
NOTE: Biohazard
All parts should be considered infectious. If necessary, please wear
7.2.4 Checking Reagent/ Sample Syringe

Open the window which is on the left part of the analyzing unit and you can see the syringe
100
located in the upper-right part. See the figure below.
Figure 7-5: Sample syringe and reagent syringe
Check the syringe for leakage by following the procedure below:

1
Check the T-piece for leakage. If yes, please contact Landwind.
Check the lower plunger guide cap for leakage. If yes, please contact
Landwind.
Close the window on the left door of the analyzing unit
7.2.5 Checking Purified Water Tank

The purified water tank is located at the left of the analyzing unit .as shown in the figure
below.
Figure7-6: Purified water tank
Perform the following steps to check the purified water tank:

1
Check if the bottom of the purified water tank is clean. If not, take it out and
wash it thoroughly and then put it back.
7.2.6 Checking Waste Tank and Tubing

The waste tubing is located by the side of the purified water tank on the left part of the
analyzing unit. See the figure below.
101
Figure 7-7: Waste tubing connector
Perform the following steps to check the waste tubing:

1
Check the connections between the waste tubing and the counterpart on the
analyzing unit. If you see leaks, wipe off the liquid with clean gauze. Loosen the
connector by unscrewing it counterclockwise and check the waste tubing for
blockage. Remove the buildup and tighten the connector again. If leakage
remains, please contact Landwinds local office.
Check if the waste tubing is bent. If yes, tidy it up.
If you use a waste tank, check it for leakage and overflow. If you see leakage,
replace the waste tank; if you see overflow, empty the waste tank. If the waste
liquid is discharged directly to the drain hole, check the drain hole for overflow
and clean up the sewer if overflow occurs.
NOTE: Biohazard
All waste liquids should be considered infectious. If necessary, please
wear gloves when working with waste liquids.
Waste liquid shall be disposed of according to the regulations of your
local environment department.
102
7.3 Weekly Maintenance

7.3.1 Cleaning Primary Filter of Purified Water
Pull out the purified water tank, take out the water pipe and remove the primary filter.
See the figure below.
Check the primary filter is clean .if it is dirty:

1
Wash the primary filter thoroughly with tap water and wash it again with purified water.
2.
Connect the primary filter with the water pipe and then put them back in the purified
water tank.
NOTE
When putting back the primary filter, ensure it reaches the tank bottom;
otherwise, unreliable test results may be caused.
7.3.2 Cleaning Waste Tank

You are not required to perform the following steps if the waste liquid is discharged
directly to the sewer. If needed, clean the waste tank as follows:
103
Uncap the waste tank and remove the waste tubing.
Take out the waste tank, clean it thoroughly with a brush and then put it back.
NOTE: Biohazard
All waste liquids should be considered infectious. If necessary, please
wear gloves when working with waste liquids.
7.3.3 Cleaning Reagent/Sample Disk Refrigerator

1
Switch the Power of the analyzing unit OFF.
Remove the sample/reagent disk cover, take out the reagent bottles and reagent
disk, wipe the reagent disk with clean gauze dipped with wash solution until no
stain is found, then dry the reagent disk with clean gauze. See the figure below.
Install the reagent disk.
Install the sample/reagent disk cover.
NOTE: Biohazard
All stains should be considered infectious. If necessary, please wear
gloves during operation.
7.4 Monthly Maintenance

7.4.1 Cleaning Wash Pools
1
Remove the sample and reagent probes from the washing positions.
Use a cotton swab dipped with wash solution to wipe the interior and exterior of
the probe wash pool until no stain is found, and then dry them with clean gauze.
Remove the mixer from the washing position.
Use a cotton swab dipped with wash solution to wipe the interior and exterior of
the mixer wash pool until no stain is found, and then dry them with clean gauze.
Move the sample and reagent probes back to their wash pools.
104
NOTE: Biohazard
7.4.2 Cleaning Reaction Compartment

1
Remove the reaction disk cover .See the figure below.
Loosen the screws fixing the reaction disk.
Hold two sides of the reaction disk, and take it out to the upright direction, as the below
figure:
Wipe the inside of the reaction compartment with clean gauze or a wash solution-dipped
cotton swab until no stain is found, and then dry it with clean gauze. See the figure
below.
Install the reaction disk and tighten the screws.
install the reaction disk cover.
NOTE: Biohazard
105
7.4.3 Cleaning Rotors

1
Move the mixer to a position convenient for cleaning its rotor.
Wipe the rotor gently with clean gauze until no dust or stain is found, rub it with
lubricant and pull it upwards and downwards, ensuring the lubricant is evenly
applied.
Clean the rotors of the sample probe in the same way as the mixer rotor.
Move the sample and the mixer back to their wash pools.
7.5 As-Needed Maintenance

7.5.1 Unclogging Sample Probe and Reagent Probe
When the sample probe or reagent probe is blocked, you should unclog it by performing
the following steps:
1
2
Move the probe to a proper position and remove the arm cover as shown below.
Disconnect the Teflon tube from the probe. See the figure below.
106
Disconnect the cable from the liquid level detection board as shown below.
Loosen the retaining spring.
Pull out the probe upwards.
Use a 0.3mm stainless steel wire to unclog the probe from the tip upwards. Repeat your
operations for several times.
Connect a single-use syringe to the fluid connector with soft tubing and inject water to the
tubing. If you see water spray in line from the probe tip, the probe is clean.
Install the probe and the arm cover.
10
Move the sample probe back to their wash pools.
NOTE: Biohazard
The sample probe and reagent probe should be considered infectious.
If necessary, please wear gloves when working around it.
7.5.2 Replacing Sample Probe

If the sample probe is broken or bent or cannot be unclogged due to serious blockage,
follow the following steps and replace it:
1
107
Move the probe to a proper position, remove the arm cover, disconnect the
Teflon tube from the sample probe and then unplug the sensor cable from the
liquid level detector
Loosen the retaining spring and remove the probe.
Install the new probe and then the retaining spring, connect the tubing to the
fluid connector, insert the sensor cable to the level detection board, and then
install the arm cover.
Move the sample reagent probe back to their wash pools.
NOTE: Biohazard
The sample probe and reagent probe should be considered infectious.
If necessary, please wear gloves when working around it.
7.5.3 Replacing Mixer

1
If the mixer is broken, bent or hangs liquid, replace it with the following steps:
Move the mixer to a position convenient for removing.
Loosen the two retaining screws on the mixer rotor as shown below.
Remove the mixer.
Install the new mixer to the rotor properly.
Tighten the two retaining screws on the rotor.
NOTE: Biohazard
The mixer should be considered infectious. Please wear gloves when
working around it.
7.5.4 Replacing Lamp

If the lamp has been used for over half a year or the system reminds you to replace it,
108
replace the lamp with the following steps:

1
Place the Power of the analyzing unit to OFF and wait 30 minutes before
proceeding to the next step.
2
Remove the reaction disk cover.
Loosen the retaining screws on the reaction disk and remove the reaction disk
to expose the lamp housing as shown below.
Loosen the retaining screws on the lamp housing.
Disconnect the power cord of the lamp.
109
Remove the old lamp.
Install the new lamp, tighten the retaining screws and connect the power cord.
Install the reaction disk and tighten its retaining screws.
Install the wash probes and tighten the retaining knob.
Install the reaction disk cover.
NOTE: High Temperature, Burn

Before replacing the lamp, please switch off the Main Power and then
wait at least 30 minutes for the lamp to cool down before touching it.
NOTE: Strong Light

Before replacing the lamp, ensure the analyzing unit has been
powered off; otherwise the lamp light may hurt your eyes.
NOTE: Screw Off

Exercise caution when loosening or tightening the lamp screws.
Ensure the screws are loosened or tightened safety without falling off.
7.5.5 Replacing Syringe

1
open the window which is on the left door of the analyzing unit and you can see
the syringe
Loosen the three retaining screws on upper and lower part of the syringe.
110
Remove the syringe and T-piece by grabbing the metal part of the upper
syringe part and unscrewing it counterclockwise.
Install the new syringe with its thread part inserted into the T-piece and then
screw it clockwise to tighten it.
Tighten the retaining screws on upper and lower part of the syringe.
Close the window.
NOTE: Sealing Gasket

A white sealing gasket is applied inside the thread hole of the T-piece.
Exercise caution when working with the T-piece.
7.5.6 Replacing Secondary Filter of Purified Water

If the secondary filter of purified water gets dirty or the exterior/interior wash fluid becomes
less, replace the secondary filter with the following steps:
1 Place the Power of the analyzing unit to OFF.
2
Open the left door of the analyzing unit. You can see the secondary filter under the
syringe. See the figure below.
111
Remove the secondary filter.
Install a new one
Close the front doors.
7.6 List of Replacement Apparatus

7.6.1 List of replacement apparatus for User
The follow apparatus, user can replace them by himself.
1.
Sample Probe, Mixer.
2.
3.
Syringe.
Lamp.
7.6.2 List of replacement apparatus for Servicing engineer

The follow apparatus, must be replaced by servicing engineer.
1.
Main unit power of LW C100plus
2.
Analyzing unit power switch of LW C100plus
3.
Other parts of LW C100plus not including the replacement apparatus for User List.
7.7 Maintenance Log Sheets

The following tables list the parts to be maintained and the recommended maintenance
schedules. Please copy them every month and place a check mark in corresponding day column
after performing the maintenance item.
112
______Year____Month
Maintenance Records
Daily Maintenance
1
1
Cleaning Panels of
Analyzing Unit
Cleaning Sample Probe

and Mixer
Checking Sample Syringe

and Reagent Syringe
Checking Purified Water

Tank
Checking Waste Tank and

Tubing
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
19
20
21
22
23
24
25
26
27
28
29
30
31
Maintenance Records
Weekly Maintenance
1
1
Cleaning Primary Filter

of Purified Water
Cleaning Waste Tank
Cleaning Reagent Disk,

Sample Disk and
Refrigerator
10
11
12
13
14
15
16
17
18
113
______Year____Month
Maintenance Records
Monthly Maintenance
1
1
Cleaning Wash Pools
Cleaning Reaction
Compartment
Cleaning Rotors
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
19
20
21
22
23
24
25
26
27
28
29
30
31
Maintenance Records
As-Needed Maintenance
1
1
Unclogging Sample Probe

and Reagent Probe
Replacing Sample Probe

and Reagent Probe
Replacing Mixer
Replacing Lamp
Replacing Syringe
Replacing Secondary
Filter of Purified Water
10
11
12
13
14
15
16
17
18
114
Chapter 8 Appendices
8.1 Terminology
8.1.1 AD Value
The light that reaches the detector generates current, which is amplified and then transferred
to photovoltage (analog signals) after passing through the fixed resistor. The photovoltage is
converted to corresponding numeric value via the AD (analog-digital) converter. The obtained
numeric value is an AD value.
8.1.2 Dark Current

Dark current refers to the AD value obtained when the lamp is turned off, e.g. no signal light is
transmitted. It is equivalent to the circuit background and should be subtracted during absorbance
calculating.
8.1.3 Water Blank

Water blank refers to the absorbance of a cuvette filled with purified water..Absorbance is a
relative concept and based upon the standard absorbance value. In the LW C100plus,the
absorbance of the water blank is 0 and should be subtracted for calculating any other absorbance.
8.1.4 Measuring Point

The specific moment for photoelectric measuring is called a measuring point and indicated by
a numeric value. Each measuring point is strictly determined and closely related with one another.
In the LW C100plus, each reaction process is divided into 49 measuring points. The interval
between two is 24s in fast mode and 36s in normal mode.
8.1.5 Absorbance
Absorbance is the logarithm of minus quotient between the transmitted light intensity and the
input light intensity. In the LW C100plus, transmitted light intensity is the AD value of a reaction
cuvette filled with distilled water; the final absorbance is the product of the calculated value
20000.
115
8.1.6 Reaction Curve

Reaction curve consists of several points with measuring point as the X-coordinate and
absorbance as the Y-coordinate. The following figure shows a typical reaction curve of the
LW C100plus.
Absorbance
Measuring Point
8.1.7 Response
Response refers to the absorbance change before and after the reaction, or the absorbance
change rate during the reaction process.
8.1.8 Calibration
Calibration is a sample measurement, during which one or more samples (or calibrators) with
given concentration (or activity) are measured to get its response. According to the set calibration
method (linear or nonlinear), an optimal curve is fit based on the given concentration and the
calculated response and used to generate an equation. By using the curve, a sample can be
measured to get its response, which is then employed to calculate its concentration or activity.
8.1.9 Calibration Curve

Calibration curve is a curve fit by the optimal equation based on several points with
concentration (or activity) as the X-coordinate and response as the Y-coordinate.
8.1.10 Calibration Parameter

Calibration parameter refers to any other item rather than concentration and response in a
calibration formula.
8.2 Technical Parameters

Centre wavelength deviation
2nm
116
Half-wave width
12nm
Stray light
0.3%
Accuracy and Fluctuation of

Temperature
Deviation 0.2fluctuation0.1
Throughput
Up to 150 test/h without ISE
Sample Disk
40 sample positions
Sample Probe
With liquid level detection and

anti-collision, auto washing function
Sample Tube
Compatible with one-off blood collection tube, minimal

tube, plastic tube, and etc.
Reagent Disk
40 reagent positions
Reagent Probe
With
liquid
level
detection
and
function,,anti-collision, auto washing function
Reagent refrigeration
4-12,24 Hours refrigeration uninterrupted
Reaction cuvette
81
cuvettes
in
9
separated
section,special
semi-permanent plastic,automatic cleaning.
Constant Temperature
Solid substance heating system, temp. 370.1
Light Source
Tungsten-halogen lamp; 12V, 20W; current small and light

stable
Light Array
Full-sealed array of Interference Filters, away from mildew
Wavelength
8 wavelengths
Detector
Full-sealed photodiode array, no need to maintain in its

lifetime.
PowerVA
350
Dimension(lengthXwidthXheight
in mm)
855X620X545
Net Weight
85kg
tracking
function,
tracking
8.3 Transport and Storage

Temperature
040
Humidity
Relative Humidity should be within 30~85%.
117

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LW C100plus

Auto Chemistry Analyzer

About this manual

Manufacture date of the product

Chapter 1 Precautions on Safety and Use

Chapter 1 Precautions on Safety and Use

1.1 Safety Precautions

LW C100plus Operation Manual

Chapter 1 Precautions on Safety and Use

1.2 Precautions on Use

The LW C100plus is a fully-automated and computer-controlled chemistry analyzer

The LW C100plus is to be operated only by personnel trained and authorized by

To relocate the system, please contact Landwind or your local distributor.

LW C100plus Operation Manual

Chapter 1 Precautions on Safety and Use

LABEL PEELS OFF

The operating software installed on the operation unit is specified by

LW C100plus Operation Manual

Chapter 1 Precautions on Safety and Use

Maintain the system strictly as instructed by this manual. Inappropriate

Please take other measures to avoid delay in results,for example,use other

Please dispose of the used cuvette in compliance with the local

Medicines, anticoagulants or preservative in the samples may lead to unreliable

Hemolysis, jaundice or chylomicron in the samples may lead to unreliable test

LW C100plus Operation Manual

Chapter 1 Precautions on Safety and Use

REAGENTSCALIBRATORS and CONTROLS

Use proper reagents, calibrators and controls in the system.

Select appropriate reagents according to performance characteristics of the

Contamination among reagents by carryover may lead to unreliable test results.

CUVETTE USE LIFE

The replacement cycle for the semi-permanent cuvette is 3 months.Please replace

Some materials of the analyzer are subject to contamination regulations. Dispose

LW C100plus Operation Manual

Chapter 3 System Structure and Functions

2.2 Installation Requirements

Meeting relevant safety requirements.

AC 100V~240V, 50Hz/60Hz, The power socket should be grounded

Chapter 3 System Structure and Functions

the other end of the copper wire into the earth.

Away from brush-type motors and electrical-contacts equipments which are

Diameter of the particle in water shall be less than microns.

Waste liquid shall be disposed of compliantly with local regulations.

2.3 Connecting Purified Water Bucket

BIOHAZARDWear gloves and lab coat and, if necessary, goggles.

2.4 Connecting Waste Bucket

BIOHAZARD Wear gloves and lab coat and, if necessary, goggles.

2.5 Installing or Removing Reagent/Sample Disk

1. install reagent/sample disk,hold the handle in the center of reagent/sample disk,align

LW C100plus Operation Manual

Chapter 3 System Structure and Functions

Figure 2-1 Structure of the Reagent/Sample Disk

Before installing/removing reagent/sample disk,make sure that all moving parts

Wear gloves and lab coat and, if necessary, goggles.

The reagent/sample disk and the reagent/sample compartment may be

2.6 Installing or Removing Sample Tubes

Before installing/removing sample tubes,make sure the probe and

Wear gloves and lab coat and, if necessary, goggles.

2.7 Installing or Removing Reagent Bottles

Chapter 3 System Structure and Functions