Furosemide Drug Study
Furosemide Drug Study
Furosemide Drug Study
B. V.
Age
20 y.o
Height
52
Diagnosis
Sex
Female
Weight
60 kg
Website
milkv.co.vu
A/N
youre welcome J
Author
DRUG DATA
Generic name:
Furosemide
CLASSIFICATION
Pharmacologic:
Loop diuretic
Trade name/s:
Lasix
Patients dose:
20mg qo 12 hrs
Maximum dose:
40mg (may
increase dose in
increments of
20mg in 2 hr)
Minimum dose:
1 mg/kg
Therapeutic:
Loop diuretic
Pregnancy Category
Risk: C
Availability:
Tablets 20, 40,
80mg; oral
solution
10mg/ml,
40mg/ml;
injection
10mg/ml
Inhibits reabsorption
of sodium and
chloride from the
proximal and distal
tubules and
ascending limb of the
loop of Henle, leading
to a sodium-rich
dieresis
Onset: 5 min
Peak: 30 min
Duration: 2 hr
Metabolism: hepatic;
30-60 min
INDICATIONS
General:
> Oral, IV: Edema
associated with
heart failure,
cirrhosis, renal
disease
> IV: acute
pulmonary edema
> oral:
hypertension
Patients actual
indication:
Furosemide is
given to patient to
treat acute
pulmonary
congestion and
hypertension
Distribution: crosses
placenta; enters
breast milk
Route:
IVTT
Source: 2011
Lippincotts NDG
MECHANISM OF
ACTION
Source: 2011
Lippincotts NDG
Source: 2011
Lippincotts NDG
Source: 2011
Lippincotts NDG
CONTRAINDICATI
ON
Contraindicated with
allergy to furosemide,
sulphonamides; allergy
to tartrazine; anuria,
severe renal failure;
hepatic coma;
pregnancy; lactation
Precaution:
Use cautiously with SLE,
gout, diabetes mellitus
Interactions:
> drug-drug: increased
risk of cardia arrhythmias
with cardiac glycosides;
increased risk of
ototoxicity with
aminoglycoside
antibiotics, cisplatin;
decreased absorption of
furosemide with
phenytoin; decreased GI
absorption with charcoal;
may reduce effect of
insulin or oral
antidiabetics because
blood glucose levels can
become elevated
Source: 2011
Lippincotts NDG
ADVERSE
EFFECTS
CNS: dizziness,
vertigo,
paresthesias,
xanthopsia,
weakness
CV: orthostatic
hypertension,
thrombophlebitis
Dermatologic:
photosensitivity,
pruritus, urticaria,
purpura
GI: nausea,
anorexia, vomiting,
oral and gastric
irritation
GU: nocturia,
glycosuria, urinary
bladder spasm
Hematologic:
leukopenia,
anemia,
thrombocytopenia,
Other: muscle
cramps and muscle
spasms
Source: 2011
Lippincotts NDG
NURSING
RESPONSIBILITIE
S
Before:
> check doctors order
> assess allergy to furosemide,
sulfonamides, tartrazine
> do not mix parenteral solution with
highly acidic solutions with ph below
3.5
> do not expose to light, which may
discolour tablets or solution
> educate the patient about the
purpose and importance of the drug
During:
> check the patency of the IV site and
IV line
> Give early in the day so that
increased urination will not disturb
sleep
> administer the right dose at the
right time
> measure and record weight to
monitor fluid changes
After:
> monitor blood glucose levels
> arrange to monitor serum
electrolytes, hydration, liver and renal
function
> arrange for potassium-rich diet or
supplemental potassium as needed
> report loss or gain of more than
1.5kg in 1 day, swelling in your ankles
or fingers, unusual bleeding or
bruising
> document and record.